DNA-binding properties and cytotoxicity of extended aromatic bisamidines in breast cancer MCF-7 cells

Polish Journal of Pharmacology

Volumn 53, Issue 2, 2001, Pages 143-147

  Bielawski, K ^a   Wolczynski S ^a   Bielawska, A ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

Bisamidines; Breast cancer; Cytotoxicity; DNA binding; MCF 7 cells

Indexed keywords

1,4 BIS[2 [5 [4 [(N CYCLOPENTYL)AMIDINOPHENYL]FURYL] 2 CARBOXAMIDO]]BUTANE DIHYDROCHLORIDE; 1,4 BIS[2 [5 [4 [(N CYCLOPROPYL)AMINIDOPHENYL]FURYL] 2 CARBOXAMIDO]]BUTANE DIHYDROCHLORIDE; 1,4 BIS[2 [5 [4 [(N ISOPROPYL)AMIDINOPHENYL]FURYL] 2 CARBOXAMIDO]]BUTANE DIHYDROCHLORIDE; 4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; AMIDINE; AROMATIC BISAMIDINE DERIVATIVE; DNA; ETHIDIUM; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; ASSAY; BINDING AFFINITY; BREAST CANCER; CANCER CELL CULTURE; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DRUG DNA BINDING; DRUG POTENCY; DRUG STRUCTURE; HUMAN; HUMAN CELL;

AMIDINES; ANIMALS; BINDING SITES; BISBENZIMIDE; BREAST NEOPLASMS; CATTLE; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLUORESCENT DYES; HUMANS; TUMOR CELLS, CULTURED;

EID: 0035001172     PISSN: 12306002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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