Nicotinic mechanisms in the autonomic control of organ systems

Journal of Neurobiology

Volumn 53, Issue 4, 2002, Pages 568-579

  De Biasi, Mariella ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Autonomic ganglia; Bladder innervation; Enteric nervous system; Heart innervation; Knockout mice; Nicotinic receptors; Nicotinic subunits

Indexed keywords

CHOLINERGIC RECEPTOR; NICOTINIC RECEPTOR; RECEPTOR SUBUNIT;

ARTICLE; AUTONOMIC GANGLION; AUTONOMIC NERVOUS SYSTEM; BLADDER; CENTRAL NERVOUS SYSTEM; HEART; HUMAN; INTESTINE; NONHUMAN; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION;

ANIMALS; GANGLIA, AUTONOMIC; HUMANS; MICE; MUTATION; PROTEIN SUBUNITS; RECEPTORS, NICOTINIC;

EID: 0036891194     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/neu.10145     Document Type: Article

References (157)

1. Alian M, Gabella G. 1996. Decrease and disappearance of intramural neurons in the rat bladder during post-natal development. Neurosci Lett 218:103-106.
2. Alm P, Elmer P. 1975. Adrenergic and cholinergic innervation of the rat urinary bladder. Acta Physiol Scand 94:36-45.
3. Ambache N, Freeman MA. 1968. Atropine-resistant longitudinal muscle spasms due to excitation of non-cholinergic neurones in Auerbach's plexus. J Physiol 199:705-727.
4. Anand R, Conroy WG, Schoepfer R, Whiting P, Lindstrom J. 1991. Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes have a pentameric quaternary structure. J Biol Chem 266:11192-11198.
5. Anderson CR. 1998. Identification of cardiovascular pathways in the sympathetic nervous system. Clin Exp Pharmacol Physiol 25:449-452.
6. Anneren G, Meurling S, Olsen L. 1991. Megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS), an autosomal recessive disorder: Clinical reports and review of the literature. Am J Med Genet 41:251-254.
7. Applebaum AE, Vance WH, Coggeshall RE. 1980. Segmental localization of sensory cells that innervate the bladder. J Comp Neurol 192:203-209.
8. Ardell JL, Randall WC. 1986. Selective vagal innervation of sinoatrial and atrioventricular nodes in canine heart. Am J Physiol 251:H764-H773.
9. Ardell JL, Randall WC, Cannon WJ, Schmacht DC, Tasdemiroglu E. 1988. Differential sympathetic regulation of automatic, conductile, and contractile tissue in dog heart. Am J Physiol 255:H1050-H1059.
10. Armour JA, Hopkins DA. 1990. Activity of canine in situ left atrial ganglion neurons. Am J Physiol 259:H1207-H1215.
11. Armour JA, Collier K, Kember G, Ardell JL. 1998. Differential selectivity of cardiac neurons in separate intrathoracic autonomic ganglia. Am J Physiol 274:R939-R949.
12. Bibevski S, Zhou Y, McIntosh JM, Zigmond RE, Dunlap ME. 2000. Functional nicotinic acetylcholine receptors that mediate ganglionic transmission in cardiac parasympathetic neurons. J Neurosci 20:5076-5082.
13. Blomquist TM, Priola DV, Romero AM. 1987. Source of intrinsic innervation of canine ventricles: A functional study. Am J Physiol 252:H638-H644.
14. Boorman JP, Groot-Kormelink PJ, Sivilotti LG. 2000. Stoichiometry of human recombinant neuronal nicotinic receptors containing the b3 subunit expressed in Xenopus oocytes. J Physiol 529(Pt 3):565-577.
15. Bornstein JC. 1994. Local neural control of intestinal motility: Nerve circuits deduced for the guinea-pig small intestine. Clin Exp Pharmacol Physiol 21:441-452.
16. Boulter J, Evans K, Goldman D, Martin G, Treco D, Heinemann S, Patrick J. 1986. Isolation of a cDNA clone coding for a possible neural nicotinic acetylcholine receptor alpha-subunit. Nature 319:368-374.
17. Briggs CA, Cooper JR. 1982. Cholinergic modulation of the release of [3H] acetylcholine from synaptosomes of the myenteric plexus. J Neurochem 38:501-508.
18. Brook RD, Julius S. 2000. Autonomic imbalance, hypertension, and cardiovascular risk. Am J Hypertens 13:112S-122S.
19. Burnstock G, Allen TGJ, Hassall CJS, Pittam BS. 1987. Properties of intramural neurones cultured from the heart and bladder. In: Heym C, editor. Histochemistry and Cell Biology of Autonomic Neurones and Paraganglia. Heidelberg: Springer Verlag, p 323-328.
20. Burnstock G, Campbell G, Rand MJ. 1966. The inhibitory innervation of the taenia of the guinea-pig caecum. J Physiol 182:504-526.
21. Carpenter FG, Rubin RM. 1967. The motor innervation of the rat urinary bladder. J Physiol (Lond) 192:609-617.
22. Carrive P, Bandler R, Dampney RA. 1989. Viscerotopic control of regional vascular beds by discrete groups of neurons within the midbrain periaqueductal gray. Brain Res 493:385-390.
23. Champtiaux N, Han ZY, Bessis A, Rossi FM, Zoli M, Marubio L, McIntosh JM, Changeux JP. 2002. Distribution and pharmacology of alpha 6-containing nicotinic acetylcholine receptors analyzed with mutant mice. J Neurosci 22:1208-1217.
24. Chang KT, Berg DK. 1999. Nicotinic acetylcholine receptors containing alpha7 subunits are required for reliable synaptic transmission in situ. J Neurosci 19:3701-3710.
25. Chesher GB. 1967. Acetylcholine in extracts and perfusates of urinary bladder. J Pharm Pharmacol 19:445-455.
26. Cho CH, Ogle CW, Wong SH, Lam SK. 1987. Effects of ethanol and nicotine on gastrin and somatostatin release in rats. Horm Res 25:113-119.
27. Chung MY, Huang CB, Chuang JH, Ko SF, Chen L. 1998. Megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS): A case report. Chang Keng I Hsueh 21:92-96.
28. Cimino M, Marini P, Fornasari D, Cattabeni F, Clementi F. 1992. Distribution of nicotinic receptors in cynomolgus monkey brain and ganglia: Localization of alpha 3 subunit mRNA, alpha-bungarotoxin and nicotine binding sites. Neuroscience 51:77-86.
29. Coggan JS, Paysan J, Conroy WG, Berg DK. 1997. Direct recording of nicotinic responses in presynaptic nerve terminals. J Neurosci 17:5798-5806.
30. Collier B, Katz HS. 1975. Studies upon the mechanism by which acetylcholine releases surplus acetylcholine in a sympathetic ganglion. Br J Pharmacol 55:189-197.
31. Colquhoun LM, Patrick JW. 1997. Alpha3, beta2, and beta4 form heterotrimeric neuronal nicotinic acetylcholine receptors in Xenopus oocytes. J Neurochem 69:2355-2362.
32. Conroy WG, Berg DK. 1995. Neurons can maintain multiple classes of nicotinic acetylcholine receptors distinguished by different subunit compositions. J Biol Chem 270:4424-4431.
33. Cooper E, Couturier S, Ballivet M. 1991. Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor. Nature 350:235-238.
34. Costa M, Brookes SJ. 1994. The enteric nervous system. Am J Gastroenterol 89:S129-S137.
35. Costa M, Brookes SJ, Steele PA, Gibbins I, Burcher E, Kandiah CJ. 1996. Neurochemical classification of myenteric neurons in the guinea-pig ileum. Neuroscience 75:949-967.
36. Couturier S, Bertrand D, Matter JM, Hernandez MC, Bertrand S, Millar N, Valera S, Barkas T, Ballivet M. 1990. A neuronal nicotinic acetylcholine receptor subunit (α 7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BgTx. Neuron 5:847-856.
37. Cuevas J, Adams DJ. 1996. Vasoactive intestinal polypeptide modulation of nicotinic ACh receptor channels in rat intracardiac neurones. J Physiol 493:503-515.
38. Cuevas J, Adams DJ. 2000. Substance P preferentially inhibits large conductance nicotinic ACh receptor channels in rat intracardiac ganglion neurons. J Neurophysiol 84:1961-1970.
39. Cuevas J, Berg DK. 1998. Mammalian nicotinic receptors with alpha7 subunits that slowly desensitize and rapidly recover from alpha-bungarotoxin blockade. J Neurosci 18:10335-10344.
40. Cuevas J, Roth AL, Berg DK. 2000. Two distinct classes of functional 7-containing nicotinic receptor on rat superior cervical ganglion neurons. J Physiol 525(Pt 3):735-746.
41. De Biasi M, Nigro F, Xu W. 2000. Nicotinic acetylcholine receptors in the autonomic control of bladder function. Eur J Pharmacol 393:137-140.
42. de Groat WC. 1998. Anatomy of the central neural pathways controlling the lower urinary tract. Eur Urol 34:2-5.
43. de Groat WC, Booth AM. 1980. Physiology of the urinary bladder and urethra. Ann Intern Med 92:312-315.
44. De Groat WC, Saum WR. 1976. Synaptic transmission in parasympathetic ganglia in the urinary bladder of the cat. J Physiol 256:137-158.
45. de Groat WC, Yoshimura N. 2001. Pharmacology of the lower urinary tract. Annu Rev Pharmacol Toxicol 41:691-721.
46. de Groat WC, Vizzard MA, Araki I, Roppolo J. 1996. Spinal interneurons and preganglionic neurons in sacral autonomic reflex pathways. Prog Brain Res 107:97-111.
47. Dickerson LW, Rodak DJ, Fleming TJ, Gatti PJ, Massari VJ, McKenzie JC, Gillis RA. 1998. Parasympathetic neurons in the cranial medial ventricular fat pad on the dog heart selectively decrease ventricular contractility. J Auton Nerv Syst 70:129-141.
48. Ekstrom J, Elmer M. 1980. Compensatory increase of responses to nerve stimulation of the partially denervated rat urinary bladder. Acta Physiol Scand 110:21-29.
49. Elbadawi A. 1982. Neuromorphologic basis of vesicourethral function. I. Histochemistry, ultrastructure and function of intrinsic nerves in the bladder and urethra. Neurourol Urodynam 1:3-50.
50. Elbadawi A. 1988. Neuromuscolar mechanisms of micturition. In: Yalla SV, Elbadawi Me, editors. Neurology and Urodynamics: Principle and Practice. New York: McMillan, p 3-36.
51. Elbadawi A, Schenk EA. 1966. Dual innervation of the mammalian urinary bladder. Am J Anat 119:405-428.
52. Elgoyen AB, Johnson DS, Boulter J, Vetter DE, Heinemann S. 1994. α9: An acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells. Cell 79:705-715.
53. Elgoyhen AB, Vetter DE, Katz E, Rothlin CV, Heinemann SF, Boulter J. 2001. Aalpha10: A determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells. Proc Natl Acad Sci USA 98:3501-3506.
54. Fandriks L, Hamlet A, Jonson C. 1994. Duodenal wall motility, mucosal net fluid and alkaline secretion in response to luminal acid: Role of the vagal nerves and cholinergic transmission. Acta Physiol Scand 150:273-279.
55. Fandriks L, Jonson C, Hamlet A, Danielsen N, Johansson BR. 1995. Sympatho-adrenergic inhibition of basal and acid-induced changes in duodenal motility, mucosal net fluid and alkaline secretion in the anaesthetized cat. Acta Physiol Scand 153:211-219.
56. Fieber LA, Adams DJ. 1991. Acetylcholine-evoked currents in cultured neurones dissociated from rat parasympathetic cardiac ganglia. J Physiol 434:215-237.
57. Forster I, Bertrand D. 1995. Inward rectification of neuronal nicotinic acetylcholine receptors investigated by using the homomeric alpha 7 receptor. Proc R Soc Lond B Biol Sci 260:139-148.
58. Franceschini D, Orr-Urtreger A, Yu W, Mackey LY, Bond RA, Armstrong D, Patrick JW, Beaudet AL, De Biasi M. 2000. Altered baroreflex in α7 deficient mice. Behav Brain Res 113:3-10.
59. Furness JB, Bornstein JC, Smith TK, Murphy R, Pompolo S. 1989. Correlated functional and structural analysis of enteric neural circuits. Arch Histol Cytol 52:161-166.
60. Gagliardi M, Randall WC, Bieger D, Wurster RD, Hopkins DA, Armour JA. 1988. Activity of in vivo canine cardiac plexus neurons. Am J Physiol 255:H789-H800.
61. Gallagher JP, Griffith WH, Shinnick-Gallagher P. 1982. Cholinergic transmission in cat parasympathetic ganglia. J Physiol 332:473-486.
62. Galligan JJ, Bertrand PP. 1994. ATP mediates fast synaptic potentials in enteric neurons. J Neurosci 14:7563-7571.
63. Galligan JJ, Burks TF. 1986. Cholinergic neurons mediate intestinal propulsion in the rat. J Pharmacol Exp Ther 238:594-598.
64. Galligan JJ, LePard KJ, Schneider DA, Zhou X. 2000. Multiple mechanisms of fast excitatory synaptic transmission in the enteric nervous system. J Auton Nerv Syst 81:97-103.
65. Gatti PJ, Johnson TA, McKenzie J, Lauenstein JM, Gray A, Massari VJ. 1997. Vagal control of left ventricular contractility is selectively mediated by a cranioventricular intracardiac ganglion in the cat. J Auton Nerv Syst 66:138-144.
66. Gatti PJ, Johnson TA, Phan P, Jordan IK, 3rd, Coleman W, Massari VJ. 1995. The physiological and anatomical demonstration of functionally selective parasympathetic ganglia located in discrete fat pads on the feline myocardium. J Auton Nerv Syst 51:255-259.
67. Gershon MD, Erde SM. 1981. The nervous system of the gut. Gastroenterology 80:1571-1594.
68. Gibbins IL. 1991. Vasomotor, pilomotor and secretomotor neurons distinguished by size and neuropeptide content in superior cervical ganglia of mice. J Auton Nerv Syst 34:171-183.
69. Gibbins IL, Jobling P, Messenger JP, Teo EH, Morris JL. 2000. Neuronal morphology and the synaptic organisation of sympathetic ganglia. J Auton Nerv Syst 81:104-109.
70. Gotti C, Hanke W, Maury K, Moretti M, Ballivet M, Clementi F, Bertrand D. 1994. Pharmacology and biophysical properties of alpha 7 and alpha 7-alpha 8 alpha-bungarotoxin receptor subtypes immunopurified from the chick optic lobe. Eur J Neurosci 6:1281-1291.
71. Groot-Kormelink PJ, Boorman JP, Sivilotti LG. 2001. Formation of functional alpha3beta4alpha5 human neuronal nicotinic receptors in Xenopus oocytes: A reporter mutation approach. Br J Pharmacol 134:789-796.
72. Groot-Kormelink PJ, Luyten WH, Colquhoun D, Sivilotti LG. 1998. A reporter mutation approach shows incorporation of the "orphan" subunit beta3 into a functional nicotinic receptor. J Biol Chem 273:15317-15320.
73. Hardwick JC, Mawe GM, Parsons RL. 1995. Evidence for afferent fiber innervation of parasympathetic neurons of the guinea-pig cardiac ganglion. J Auton Nerv Syst 53:166-174.
74. Hirst GD, McKirdy HC. 1974. A nervous mechanism for descending inhibition in guinea-pig small intestine. J Physiol 238:129-143.
75. Janig W, McLachlan EM. 1992. Characteristics of functionspecific pathways in the sympathetic nervous system. Trends Neurosci 15:475-481.
76. Ji S, Tosaka T, Whitfield BH, Katchman AN, Kandil A, Knollmann BC, Ebert SN. 2002. Differential rate responses to nicotine in rat heart: Evidence for two classes of nicotinic receptors. J Pharmacol Exp Ther 301:893-899.
77. Julius S, Valentini M. 1998. Consequences of the increased autonomic nervous drive in hypertension, heart failure and diabetes. Blood Press Suppl:5-13.
78. Kadowaki M, Wade PR, Gershon MD. 1996. Participation of 5-HT3, 5-HT4, and nicotinic receptors in the peristaltic reflex of guinea pig distal colon. Am J Physiol 271:G849-G857.
79. Keast JR, Booth AM, de Groat WC. 1989. Distribution of neurons in the major pelvic ganglion of the rat which supply the bladder, colon or penis. Cell Tissue Res 256:105-112.
80. Keast JR, Luckensmeyer GB, Schemann M. 1995. All pelvic neurons in male rats contain immunoreactivity for the synthetic enzymes of either noradrenaline or acetylcholine. Neurosci Lett 196:209-212.
81. Kirchgessner AL, Liu MT. 1998. Immunohistochemical localization of nicotinic acetylcholine receptors in the guinea pig bowel and pancreas. J Comp Neurol 390:497-514.
82. Kristufek D, Stocker E, Boehm S, Huck S. 1999. Somatic and prejunctional nicotinic receptors in cultured rat sympathetic neurones show different agonist profiles. J Physiol (Lond) 516:739-756.
83. Kubota M, Ikeda K, Ito Y. 1989. Autonomic innervation of the intestine from a baby with megacystis microcolon intestinal hypoperistalsis syndrome: II. Electrophysiological study. J Pediatr Surg 24:1267-1270.
84. Labarca C, Schwarz J, Deshpande P, Schwarz S, Nowak MW, Fonck C, Nashmi R, Kofuji P, Dang H, Shi W, Fidan M, Khakh BS, Chen Z, Bowers BJ, Boulter J, Wehner JM, Lester HA. 2001. Point mutant mice with hypersensitive alpha 4 nicotinic receptors show dopaminergic deficits and increased anxiety. Proc Natl Acad Sci USA 98:2786-2791.
85. Langer SZ. 1997. 25 Years since the discovery of presynaptic receptors: Present knowledge and future perspectives. Trends Pharmacol Sci 18:95-99.
86. Lev-Lehman E, Bercovich D, Xu W, Stockton DW, Beaudet AL. 2001. Characterization of the human beta4 nAChR gene and polymorphisms in CHRNA3 and CHRNB4. J Hum Genet 46:362-366.
87. Liang SD, Vizi ES. 1997. Positive feedback modulation of acetylcholine release from isolated rat superior cervical ganglion. J Pharmacol Exp Ther 280:650-655.
88. Listerud M, Brussaard AB, Devay P, Colman DR, Role LW. 1991. Functional contribution of neuronal AChR subunits revealed by antisense oligonucleotides [published erratum appears in Science 1992 Jan 3;255(5040):12]. Science 254:1518-1521.
89. Luckensmeyer GB, Keast JR. 1998. Projections of pelvic autonomic neurons within the lower bowel of the male rat: An anterograde labelling study. Neuroscience 84:263-280.
90. Luebke JI, Wright LL. 1992. Characterization of superior cervical ganglion neurons that project to the submandibular glands, the eyes, and the pineal gland in rats. Brain Res 589:1-14.
91. Maggi CA, Santicioli P, Geppetti P, Frilli S, Spillantini MG, Nediani C, Hunt SP, Meli A. 1988. Biochemical, anatomical and functional correlates of postnatal development of the capsaicin-sensitive innervation of the rat urinary bladder. Brain Res 471:183-190.
92. Maggi CA, Santicioli P, Geppetti P, Furio M, Frilli S, Conte B, Fanciullacci M, Giuliani S, Meli A. 1987. The contribution of capsaicin-sensitive innervation to activation of the spinal vesico-vesical reflex in rats: Relationship between substance P levels in the urinary bladder and the sensory-efferent function of capsaicin-sensitive sensory neurons. Brain Res 415:1-13.
93. Makhija PS, Magdalene KF, Babu MK. 1999. Megacystis microcolon intestinal hypoperistalsis syndrome. Indian J Pediatr 66:945-949.
94. Mandelzys A, Pie B, Deneris ES, Cooper E. 1994. The developmental increase in ACh current densities on rat sympathetic neurons correlates with changes in nicotinic ACh receptor alpha-subunit gene expression and occurs independent of innervation. J Neurosci 14:2357-2364.
95. Marubio LM, del Mar Arroyo-Jimenez M, Cordero-Erausquin M, Lena C, Le Novere N, de Kerchove d'Exaerde A, Huchet M, Damaj MI, Changeux JP. 1999. Reduced antinociception in mice lacking neuronal nicotinic receptor subunits [in process citation]. Nature 398:805-810.
96. Massari VJ, Johnson TA, Llewellyn-Smith IJ, Gatti PJ. 1994. Substance P nerve terminals synapse upon negative chronotropic vagal motoneurons. Brain Res 660:275-287.
97. Mathie A, Colquhoun D, Cull-Candy SG. 1990. Rectification of currents activated by nicotinic acetylcholine receptors in rat sympathetic ganglion neurones. J Physiol 427:625-655.
98. Mayer EA, Naliboff BD, Chang L. 2001. Basic pathophysiologic mechanisms in irritable bowel syndrome. Dig Dis 19:212-218.
99. McAllen RM, May CN, Campos RR. 1997. The supply of vasomotor drive to individual classes of sympathetic neuron. Clin Exp Hypertens 19:607-618.
100. McGehee DS. 1999. Molecular diversity of neuronal nicotinic acetylcholine receptors. Ann NY Acad Sci 868:565-577.
101. McGehee DS, Role LW. 1995. Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons. Annu Rev Physiol 57:521-546.
102. Miller SM. 2000. Control of peripheral sympathetic prevertebral ganglion neurones by colonic mechanosensory afferents. Gut 47(Suppl 4):iv28-iv29: discussion iv36.
103. Moravec J, Moravec M. 1987. Intrinsic nerve plexus of mammalian heart: Morphological basis of cardiac rhythmical activity? Int Rev Cytol 106:89-148.
104. Mulle C, Choquet D, Korn H, Changeux JP. 1992. Calcium influx through nicotinic receptor in rat central neurons: Its relevance to cellular regulation. Neuron 8:135-143.
105. Murphy DA, O'Blenes S, Hanna BD, Armour JA. 1994. Functional capacity of nicotine-sensitive canine intrinsic cardiac neurons to modify the heart. Am J Physiol 266:R1127-R1135.
106. Nishi S, North RA. 1973. Intracellular recording from the myenteric plexus of the guinea-pig ileum. J Physiol 231:471-491.
107. Nishi S, Seino Y, Takemura J, Ishida H, Seno M, Chiba T, Yanaihara C, Yanaihara N, Imura H. 1985. Vagal regulation of GRP, gastric somatostatin, and gastrin secretion in vitro. Am J Physiol 248:E425-E431.
108. Obaid AL, Koyano T, Lindstrom J, Sakai T, Salzberg BM. 1999. Spatiotemporal patterns of activity in an intact mammalian network with single-cell resolution: Optical studies of nicotinic activity in an enteric plexus. J Neurosci 19:3073-3093.
109. Orr-Urtreger A, Broide RS, Kasten MR, Dang H, Dani JA, Beaudet AL, Patrick JW. 2000. Mice homozygous for the L250T mutation in the alpha7 nicotinic acetylcholine receptor show increased neuronal apoptosis and die within 1 day of birth. J Neurochem 74:2154-2166.
110. Orr-Urtreger A, Goldner FM, Saeki M, Lorenzo I, Goldberg L, De Biasi M, Dani JA, Patrick JW, Beaudet AL. 1997. Mice deficient in the α 7 neuronal nicotinic acetylcholine receptor lack α-bungarotoxin binding sites and hippocampal fast nicotinic currents. J Neurosci 17:9165-9171.
111. Parkman HP, Stapelfeldt WH, Williams CL, Lennon VA, Szurszewski JH. 1993. Enteric GABA-containing nerves projecting to the guinea-pig inferior mesenteric ganglion modulate acetylcholine release. J Physiol 471:191-207.
112. Patrick J, Sequela P, Vernino S, Amador M, Luetje C, Dani JA. 1993. Functional diversity of neuronal nicotinic acetylcholine receptors. Prog Brain Res 98:113-120.
113. Picciotto MR, Zoli M, Lena C, Bessis A, Lallemand Y, LeNovere N, Vincent P, Pich EM, Brulet P, Changeux JP. 1995. Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain. Nature 374:65-67.
114. Poth K, Nutter TJ, Cuevas J, Parker MJ, Adams DJ, Luetje CW. 1997. Heterogeneity of nicotinic receptors class and subunit mRNA expression among individual parasympathetic neurons from rat intracardiac ganglia. J Neurosci 17:586-596.
115. Purinton PT, Fletcher TF, Bradley WE. 1973. Gross and light microscopic features of the pelvic plexus of the rat. Anatom Rec 175:697-706.
116. Quinson N, Niel JP, Miolan JP. 2000. Nitric oxide released by gastric mechanoreceptors modulates nicotinic activation of coeliac plexus neurons in the rabbit. Eur J Neurosci 12:1521-1524.
117. 2+ permeability of mouse and chick nicotinic acetylcholine receptors expressed in transiently transfected human cells. J Physiol (Lond) 507:749-757.
118. Ramirez-Latorre J, Yu CR, Qu X, Perin F, Karlin A, Role L. 1996. Functional contributions of alpha5 subunit to neuronal acetylcholine receptor channels. Nature 380:347-351.
119. Rathner JA, McAllen RM. 1999. Differential control of sympathetic drive to the rat tail artery and kidney by medullary premotor cell groups. Brain Res 834:196-199.
120. Richardson CE, Morgan JM, Jasani B, Green JT, Rhodes J, Williams GT, Lindstrom J, Wonnacott S, Thomas GA, Smith V. 2001. Megacystis-microcolon-intestinal hypoperistalsis syndrome and the absence of the alpha3 nicotinic acetylcholine receptor subunit. Gastroenterology 121:350-357.
121. Ross SA, Wong JY, Clifford JJ, Kinsella A, Massalas JS, Horne MK, Scheffer IE, Kola I, Waddington JL, Berkovic SF, Drago J. 2000. Phenotypic characterization of an alpha 4 neuronal nicotinic acetylcholine receptor subunit knock-out mouse. J Neurosci 20:6431-6441.
122. Rust G, Burgunder JM, Lauterburg TE, Cachelin AB. 1994. Expression of neuronal nicotinic acetylcholine receptor subunit genes in the rat autonomic nervous system. Eur J Neurosci 6:478-485.
123. Sargent PB. 1993. The diversity of neuronal nicotinic acetylcholine receptors. Annu Rev Neurosci 16:403-443.
124. Schneider DA, Galligan JJ. 2000. Presynaptic nicotinic acetylcholine receptors in the myenteric plexus of guinea pig intestine. Am J Physiol Gastrointest Liver Physiol 279:G528-G535.
125. Schoepfer R, Conroy WG, Whiting P, Gore M, Lindstrom J. 1990. Brain alpha-bungarotoxin binding protein cDNAs and MAbs reveal subtypes of this branch of the ligandgated ion channel gene superfamily. Neuron 5:35-48.
126. Seguela P, Wadiche J, Dineley-Miller K, Dani JA, Patrick JW. 1993. Molecular cloning, functional properties, and distribution of rat brain α7: A nicotinic cation channel highly permeable to calcium. J Neurosci 13:596-604.
127. Selyanko AA. 1995. Properties of nicotinic postsynaptic receptor channels in ganglia. In: McLachlan EM, editor. Autonomic Ganglia. Luxembourg: Harwood Academic Publishers.
128. Selyanko AA, Derkach VA, Skok VI. 1979. Fast excitatory postsynaptic currents in voltage-clamped mammalian sympathetic ganglion neurones. J Auton Nerv Syst 1:127-137.
129. Sgard F, Charpantier E, Bertrand S, Walker N, Caput D, Graham D, Bertrand D, Besnard F. 2002. A novel human nicotinic receptor subunit, alpha10, that confers functionality to the alpha9-subunit. Mol Pharmacol 61:150-159.
130. Skok VI. 1973. Physiology of Autonomic Ganglia, Tokio: Igaku Shoin.
131. Skok VI, Selianko AA. 1978. Effect of local iontophoretic application of acetylcholine and serotonin on rabbit superior cervical ganglion neurons. Neirofiziologiia 10:519-524.
132. Smith FM, McGuirt AS, Leger J, Armour JA, Ardell JL. 2001. Effects of chronic cardiac decentralization on functional properties of canine intracardiac neurons in vitro. Am J Physiol Regul Integr Comp Physiol 281:R14741482.
133. Steele PA, Gibbins IL, Morris JL. 1996. Projections of intrinsic cardiac neurons to different targets in the guineapig heart. J Auton Nerv Syst 56:191-200.
134. Steele PA, Gibbins IL, Morris JL, Mayer B. 1994. Multiple populations of neuropeptide-containing intrinsic neurons in the guinea-pig heart. Neuroscience 62:241-250.
135. Temburni MK, Blitzblau RC, Jacob MH. 2000. Receptor targeting and heterogeneity at interneuronal nicotinic cholinergic synapses in vivo. J Physiol 525(Pt 1):21-29.
136. Thompson GW, Collier K, Ardell JL, Kember G, Armour JA. 2000. Functional interdependence of neurons in a single canine intrinsic cardiac ganglionated plexus. J Physiol 528:561-571.
137. Tougas G. 1999. The autonomic nervous system in functional bowel disorders. Can J Gastroenterol 13(Suppl A):15A-17A.
138. Trouslard J, March SJ, Brown DA. 1993. Calcium entry through nicotinic receptor channels and calcium channels in cultured superior cervical ganglion cells. J Physiol 468:53-71.
139. Vernino S, Amador M, Luetje CW, Patrick J, Dani JA. 1992. Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors. Neuron 8:127-134.
140. Wang F, Gerzanich V, Wells GB, Anand R, Peng X, Keyser K, Lindstrom J. 1996. Assembly of human neuronal nicotinic receptor alpha5 subunits with alpha3, beta2, and beta4 subunits. J Biol Chem 271:17656-17665.
141. Wiley JW, Lu YX, Owyang C. 1991. Evidence for a glutamatergic neural pathway in the myenteric plexus. Am J Physiol 261:G693-G700.
142. Williams BM, Temburni MK, Bertrand S, Bertrand D, Jacob MH. 1999. The long cytoplasmic loop of the alpha 3 subunit targets specific nAChR subtypes to synapses on neurons in vivo. Ann NY Acad Sci 868:640-644.
143. Wong D, Ogle CW. 1995. The contrasting influence of chronic nicotine intake on gastrin and gastric acid secretion. J Gastroenterol Hepatol 10:577-584.
144. Wood JD. 1994. Physiology of the enteric nervous system. In: Johnson LR, editor. Physiology of the Gastrointestinal Tract, 3rd Ed. New York: Raven Press, p 432-482.
145. Wood JD. 1999. Neurotransmission at the interface of sympathetic and enteric divisions of the autonomic nervous system. Chin J Physiol 42:201-210.
146. Wood JD, Alpers DH, Andrews PL. 1999. Fundamentals of neurogastroenterology. Gut 45(Suppl 2):II6-II16.
147. Wright LL, Luebke JI. 1989. Somatostatin-, vasoactive intestinal polypeptide- and neuropeptide Y- like immunoreactivity in eye- and submandibular gland-projecting sympathetic neurons. Brain Res 494:267-275.
148. Xu W, Gelber S, Orr-Urtreger A, Armstrong D, Lewis RA, Ou C-N, Patrick J, Role LW, De Biasi M, Beaudet AL. 1999a. Megacystis, mydriasis, and ion channel defect in mice lacking the α 3 neuronal nicotinic acetylcholine receptor. Proc Natl Acad Sci USA 96:5746-5751.
149. Xu W, Orr-Urtreger A, Nigro F, Gelber S, Ballard Sutcliffe C, Armstrong D, Patrick J, Role LW, Beaudet AL, De Biasi M. 1999b. Multiorgan autonomic dysfunction in mice lacking the β2 and the β4 subunits of neuronal nicotinic acetylcholine receptors. J Neurosci 19:9298-9305.
150. Yoshimura N, de Groat WC. 1997. Neural control of the lower urinary tract. Int J Urol 4:111-125.
151. Yu CR, Role LW. 1998a. Functional contribution of the alpha5 subunit to neuronal nicotinic channels expressed by chick sympathetic ganglion neurones. J Physiol (Lond) 509:667-681.
152. Yu CR, Role LW. 1998b. Functional contribution of the alpha7 subunit to multiple subtypes of nicotinic receptors in embryonic chick sympathetic neurones. J Physiol (Lond) 509:651-665.
153. Yu W, Mackey LY, Xu W, Beaudet AL, De Biasi M. 2000. Bradycardia and ventricular repolarization defects in mice lacking the α3 subunit of neuronal nicotinic acetylcholine receptors. In: Lester R, editor. The 10th Neuropharmacology Conference: Neuronal Nicotinic Receptors. New Orleans: Elsevier Science.
154. Yuan BX, Ardell JL, Hopkins DA, Losier AM, Armour JA. 1994. Gross and microscopic anatomy of the canine intrinsic cardiac nervous system. Anat Rec 239:75-87.
155. Zhang X, Liu C, Miao H, Gong ZH, Nordberg A. 1998. Postnatal changes of nicotinic acetylcholine receptor alpha 2, alpha 3, alpha 4, alpha 7 and beta 2 subunits genes expression in rat brain. Int J Dev Neurosci 16:507-518.
156. Zhou X, Galligan JJ, 1999a. Synaptic activation and properties of 5-Hydroxytryptamine(3) receptors in myenteric neurons of guinea pig intestine [in process citation]. J Pharmacol Exp Ther 290:803-810.
157. Zhou X, Galligan JJ. 1999b. Synaptic activation and properties of 5-hydroxytryptamine(3) receptors in myenteric neurons of guinea pig intestine. J Pharmacol Exp Ther 290:803-810.