-
1
-
-
0034603455
-
Mechanism of action studies of cytotoxic marine alkaloids: Ascididemin exhibits thiol-dependent oxidative DNA cleavage
-
Matsumoto, S. S., Sidford, M. H., Holden, J. A., Barrows, L. R., and Copp, B. R. (2000) Mechanism of Action Studies of Cytotoxic Marine Alkaloids: Ascididemin Exhibits Thiol-Dependent Oxidative DNA cleavage. Tetrahedron Lett. 41, 1667-1670.
-
(2000)
Tetrahedron Lett.
, vol.41
, pp. 1667-1670
-
-
Matsumoto, S.S.1
Sidford, M.H.2
Holden, J.A.3
Barrows, L.R.4
Copp, B.R.5
-
2
-
-
0011161546
-
Total synthesis of the pentacyclic alkaloid ascididemin
-
Bracher, F. (1989) Total synthesis of the pentacyclic alkaloid ascididemin. Heterocycles 29, 2093-2095.
-
(1989)
Heterocycles
, vol.29
, pp. 2093-2095
-
-
Bracher, F.1
-
3
-
-
0026564886
-
Copyrine alkaloids: Synthesis, spectroscopic characterization, and antimycotic/antimycobacterial activity of A- and B-ring-functionalized sampangines
-
Peterson, J. R., Zjawiony, J. K., Liu, S., Hufford, C. D., Clark, A. M., and Rogers, R. D. (1992) Copyrine alkaloids: synthesis, spectroscopic characterization, and antimycotic/antimycobacterial activity of A- and B-ring-functionalized sampangines. J. Med. Chem. 35, 4069-4077.
-
(1992)
J. Med. Chem.
, vol.35
, pp. 4069-4077
-
-
Peterson, J.R.1
Zjawiony, J.K.2
Liu, S.3
Hufford, C.D.4
Clark, A.M.5
Rogers, R.D.6
-
4
-
-
0024428281
-
Diplamine, a cytotoxic polyaromatic alkaloid from the tunicate Diplosoma sp
-
Charyulu, G. A., McKee, T. C., and Ireland, C. M. (1989) Diplamine, a cytotoxic polyaromatic alkaloid from the tunicate Diplosoma sp. Tetrahedron Lett. 30, 4201-4202.
-
(1989)
Tetrahedron Lett.
, vol.30
, pp. 4201-4202
-
-
Charyulu, G.A.1
McKee, T.C.2
Ireland, C.M.3
-
5
-
-
0000331562
-
Marine pyridoacridine alkaloids: Structure, synthesis, and biological chemistry
-
Molinski, T. F. (1993) Marine pyridoacridine alkaloids: structure, synthesis, and biological chemistry. Chem. Rev. 93, 1825-1838.
-
(1993)
Chem. Rev.
, vol.93
, pp. 1825-1838
-
-
Molinski, T.F.1
-
6
-
-
0030833832
-
Efficient and convenient pyridine ring-E formation of the cytotoxic marine alkaloid ascididemin and related analogues
-
Lindsay, B. S., Pearce, A. N., and Copp, B. R. (1997) Efficient and convenient pyridine ring-E formation of the cytotoxic marine alkaloid ascididemin and related analogues. Synth. Commun. 27, 2587-2592.
-
(1997)
Synth. Commun.
, vol.27
, pp. 2587-2592
-
-
Lindsay, B.S.1
Pearce, A.N.2
Copp, B.R.3
-
7
-
-
8344237053
-
Kuanoniamines A, B, C, and D: Pentacyclic alkaloids from a tunicate and its prosobranch mollusk predator Chelynotus semperi
-
Carroll, A. R., and Scheuer, P. J. (1990) Kuanoniamines A, B, C, and D: pentacyclic alkaloids from a tunicate and its prosobranch mollusk predator Chelynotus semperi. J. Org. Chem. 55, 4426- 4431.
-
(1990)
J. Org. Chem.
, vol.55
, pp. 4426-4431
-
-
Carroll, A.R.1
Scheuer, P.J.2
-
8
-
-
0000152808
-
A second shermilamine alkaloid from a tunicate Trididemnum sp
-
Carroll, A. R., Cooray, N. M., Poiner, A., and Scheuer, P. J. (1989) A second shermilamine alkaloid from a tunicate Trididemnum sp. J. Org. Chem. 54, 4231-4232.
-
(1989)
J. Org. Chem.
, vol.54
, pp. 4231-4232
-
-
Carroll, A.R.1
Cooray, N.M.2
Poiner, A.3
Scheuer, P.J.4
-
9
-
-
0034645771
-
Structural studies of cytotoxic marine alkaloids: Synthesis of novel ring-E analogues of ascididemin and their in vitro and in vivo biological evaluation
-
Lindsay, B. S., Christiansen, H. C., and Copp, B. R. (2000) Structural studies of cytotoxic marine alkaloids: Synthesis of novel ring-E analogues of ascididemin and their in vitro and in vivo biological evaluation. Tetrahedron 56, 497-505.
-
(2000)
Tetrahedron
, vol.56
, pp. 497-505
-
-
Lindsay, B.S.1
Christiansen, H.C.2
Copp, B.R.3
-
11
-
-
0024464131
-
Varamines A and B, new cytotoxic thioalkaloids from Lissoclinum vareau
-
Molinski, T. F., and Ireland, C. M. (1989) Varamines A and B, new cytotoxic thioalkaloids from Lissoclinum vareau. J. Org. Chem. 54, 4256-4259.
-
(1989)
J. Org. Chem.
, vol.54
, pp. 4256-4259
-
-
Molinski, T.F.1
Ireland, C.M.2
-
12
-
-
0023905863
-
Ascididemin, a novel pentacyclic aromatic alkaloid with potent antileukemic activity form the Okinawan tunicate Didemnum sp
-
Kobayashi, J., Cheng, J., Nakamura, H., Ohizumi, Y., Hirata, Y., Sasaki, T., Ohta, T., and Nozoe, S. (1988) Ascididemin, a novel pentacyclic aromatic alkaloid with potent antileukemic activity form the Okinawan tunicate Didemnum sp. Tetrahedron Lett. 29, 1177-1780.
-
(1988)
Tetrahedron Lett.
, vol.29
, pp. 1177-1780
-
-
Kobayashi, J.1
Cheng, J.2
Nakamura, H.3
Ohizumi, Y.4
Hirata, Y.5
Sasaki, T.6
Ohta, T.7
Nozoe, S.8
-
13
-
-
0025971350
-
Cytotoxic aromatic alkaloids from the ascidian Amphicarpa meridiana and Leptoclinides sp.: Meridine and 11-hydroxy ascididemin
-
Schmitz, F. J., DeGuzman, F. S., Hossain, M. B., and Vanderhelm, D. (1991) Cytotoxic aromatic alkaloids from the ascidian Amphicarpa meridiana and Leptoclinides sp.: meridine and 11-hydroxy ascididemin. J. Org. Chem. 56, 804-808.
-
(1991)
J. Org. Chem.
, vol.56
, pp. 804-808
-
-
Schmitz, F.J.1
DeGuzman, F.S.2
Hossain, M.B.3
Vanderhelm, D.4
-
14
-
-
0028945732
-
Structural requirements for biological activity of the marine alkaloid ascididemin
-
Lindsay, B. S., Barrows, L. R., and Copp, B. R. (1995) Structural requirements for biological activity of the marine alkaloid ascididemin. Bioorg. Med. Chem. Lett. 5, 739-742.
-
(1995)
Bioorg. Med. Chem. Lett.
, vol.5
, pp. 739-742
-
-
Lindsay, B.S.1
Barrows, L.R.2
Copp, B.R.3
-
15
-
-
0029039532
-
Binding to DNA and cytotoxic evaluation of ascididemin, the major alkaloid from the Mediterranean ascidian Cystodytes dellechiajei
-
Bonnard, I., Bontemps, N., Lahmy, S., Banaigs, B., Combaut, G., Francisco, C., Colson, P., Houssier, C., Waring, M. J., and Bailly, C. (1995) Binding to DNA and cytotoxic evaluation of ascididemin, the major alkaloid from the Mediterranean ascidian Cystodytes dellechiajei. Anti-Cancer Drug Des. 10, 333-346.
-
(1995)
Anti-Cancer Drug Des.
, vol.10
, pp. 333-346
-
-
Bonnard, I.1
Bontemps, N.2
Lahmy, S.3
Banaigs, B.4
Combaut, G.5
Francisco, C.6
Colson, P.7
Houssier, C.8
Waring, M.J.9
Bailly, C.10
-
16
-
-
0034664192
-
The marine alkaloid ascididemin stimulates DNA cleavage by topoisomerase II and induces apoptosis in leukemia cells
-
Dassonneville, L., Wattez, N., Baldeyrou, B., Banaigs, B., Bonnard, I., and Bailly, C. (2000) The marine alkaloid ascididemin stimulates DNA cleavage by topoisomerase II and induces apoptosis in leukemia cells. Biochem. Pharmacol. 60, 527-537.
-
(2000)
Biochem. Pharmacol.
, vol.60
, pp. 527-537
-
-
Dassonneville, L.1
Wattez, N.2
Baldeyrou, B.3
Banaigs, B.4
Bonnard, I.5
Bailly, C.6
-
17
-
-
0003536299
-
-
Clarendon Press, Oxford
-
Halliwell, B., and Gutteridge, J. M. C. (1989) Free Radicals in Biology and Medicine, 2nd ed., Clarendon Press, Oxford.
-
(1989)
Free Radicals in Biology and Medicine, 2nd Ed.
-
-
Halliwell, B.1
Gutteridge, J.M.C.2
-
18
-
-
0030570517
-
Oxidative DNA damage in human respiratory tract epithelial cells. Time course in relation to DNA strand breakage
-
Spencer, J. P. E., Jenner, A., Aruoma, O. I., Cross, C. E., Wu, R., and Halliwell, B. (1996) Oxidative DNA damage in human respiratory tract epithelial cells. Time course in relation to DNA strand breakage. Biochem. Biophys. Res. Commun. 224, 17-22.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.224
, pp. 17-22
-
-
Spencer, J.P.E.1
Jenner, A.2
Aruoma, O.I.3
Cross, C.E.4
Wu, R.5
Halliwell, B.6
-
19
-
-
0031272128
-
Electrochemical properties of some biologically active quinone derivatives: Furanquinones, pyridoquinones, and diplamine, a cytotoxic pyridoacridine alkaloid
-
Crawford, P. W., Gross, J., Lawson, K., Cheng, C. C., Dong, Q., Liu, D. F., Luo, Y. L., Szczepankiewicz, B. G., and Heathcock, C. H. (1997) Electrochemical properties of some biologically active quinone derivatives: furanquinones, pyridoquinones, and diplamine, a cytotoxic pyridoacridine alkaloid. J. Electrochem. Soc. 144, 3710-3715.
-
(1997)
J. Electrochem. Soc.
, vol.144
, pp. 3710-3715
-
-
Crawford, P.W.1
Gross, J.2
Lawson, K.3
Cheng, C.C.4
Dong, Q.5
Liu, D.F.6
Luo, Y.L.7
Szczepankiewicz, B.G.8
Heathcock, C.H.9
-
20
-
-
0001213485
-
Role of hydrogen peroxide and hydroxyl radical formation in the killing of Ehrlich tumor cells by anticancer quinones
-
Doroshow, J. H. (1986) Role of hydrogen peroxide and hydroxyl radical formation in the killing of Ehrlich tumor cells by anticancer quinones. Proc. Natl. Acad. Sci. U.S.A. 83, 4514-4518.
-
(1986)
Proc. Natl. Acad. Sci. U.S.A.
, vol.83
, pp. 4514-4518
-
-
Doroshow, J.H.1
-
21
-
-
0036015087
-
Intramolecular Michael-type addition of azadienes to 1,4-naphthoquinones instead of Aza-Diels-Alder cycloaddition: A synthesis of ascididemin
-
Cuerva, J. M, Cardenas, D. J., and Echavarren (2002) Intramolecular Michael-type addition of azadienes to 1,4-naphthoquinones instead of Aza-Diels-Alder cycloaddition: a synthesis of ascididemin. J. Chem. Soc., Perkin Trans. 1 11, 1360-1365.
-
(2002)
J. Chem. Soc., Perkin Trans. 1
, vol.11
, pp. 1360-1365
-
-
Cuerva, J.M.1
Cardenas, D.J.2
Echavarren3
-
22
-
-
0037103341
-
Synthesis and characterization of the antitumor activities of analogues of meridine, a marine pyridoacridine alkaloid
-
Delfourne, E., Darro, F., Bontemps-Subielos, N., Decaestecker, C., Bastide, J., Frydman, A., and Kiss, R. (2002) Synthesis and characterization of the antitumor activities of analogues of meridine, a marine pyridoacridine alkaloid. J. Med Chem. 45, 3765-3771
-
(2002)
J. Med. Chem.
, vol.45
, pp. 3765-3771
-
-
Delfourne, E.1
Darro, F.2
Bontemps-Subielos, N.3
Decaestecker, C.4
Bastide, J.5
Frydman, A.6
Kiss, R.7
-
23
-
-
0025264034
-
Human DNA topoisomerase II: Evaluation of enzyme activity in neoplastic tissues
-
Holden, J. A., Rolfson, D. H., and Wittwer, C. T. (1990) Human DNA topoisomerase II: evaluation of enzyme activity in neoplastic tissues. Biochemistry 29, 2127-2134.
-
(1990)
Biochemistry
, vol.29
, pp. 2127-2134
-
-
Holden, J.A.1
Rolfson, D.H.2
Wittwer, C.T.3
-
24
-
-
0028677807
-
Mechanism of action of topo II-targeted antineoplastic drugs
-
Osheroff, N., Corbett, A. H., and Robinson, M. J. (1994) Mechanism of action of topo II-targeted antineoplastic drugs. Adv. Pharmacol. (New York) 29B, 105-126.
-
(1994)
Adv. Pharmacol. (New York)
, vol.29 B
, pp. 105-126
-
-
Osheroff, N.1
Corbett, A.H.2
Robinson, M.J.3
-
25
-
-
0026093801
-
Local base sequence preferences for DNA cleavage by mammalian topoisomerase II in the presence of amsacrine or teniposide
-
Pommier, Y., Capranico, G., Orr, A., and Kohn, K. W. (1991) Local base sequence preferences for DNA cleavage by mammalian topoisomerase II in the presence of amsacrine or teniposide. Nucleic Acids Res. 19, 5973-5980
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 5973-5980
-
-
Pommier, Y.1
Capranico, G.2
Orr, A.3
Kohn, K.W.4
-
26
-
-
0027167775
-
Novel cytotoxic topisomerase II inhibiting pyrroloiminoquinones from Fijian sponges of the Genus Zyzzya
-
Radisky, D. C., Radisky, E. S., Barrows, L. R., Copp, B. R., Kramer, R. A., and Ireland, C. M. (1993) Novel cytotoxic topisomerase II inhibiting pyrroloiminoquinones from Fijian sponges of the Genus Zyzzya. J. Am. Chem. Soc. 115, 1632-1638.
-
(1993)
J. Am. Chem. Soc.
, vol.115
, pp. 1632-1638
-
-
Radisky, D.C.1
Radisky, E.S.2
Barrows, L.R.3
Copp, B.R.4
Kramer, R.A.5
Ireland, C.M.6
-
27
-
-
0027295708
-
The use of cyclic voltammetry for the evaluation of oxidative damage in biological systems
-
Kohen, R. (1993) The use of cyclic voltammetry for the evaluation of oxidative damage in biological systems. J. Pharmacol. Toxicol. Methods 29, 185-193.
-
(1993)
J. Pharmacol. Toxicol. Methods
, vol.29
, pp. 185-193
-
-
Kohen, R.1
-
28
-
-
0013351448
-
In situ time-resolved ESR studies of spin trapping by DMPO: Reevaluation of hydroxyl radical and hydrated electron trapping rates and spin adduct yields
-
Madden, K. P., and Taniguchi, H. (1996) In situ time-resolved ESR studies of spin trapping by DMPO: Reevaluation of hydroxyl radical and hydrated electron trapping rates and spin adduct yields. J. Am. Chem Soc. 23, 1453-1476.
-
(1996)
J. Am. Chem Soc.
, vol.23
, pp. 1453-1476
-
-
Madden, K.P.1
Taniguchi, H.2
-
29
-
-
0027942883
-
Inhibition of topoisomerase II catalytic activity by pyridoacridine alkaloids from a Cystodytes sp. ascidian: A mechanism for the apparent intercalator-induced inhibition of topoisomerase II
-
McDonald, L. A., Eldredge, G. S., Barrows, L. R., and Ireland C. M. (1994) Inhibition of topoisomerase II catalytic activity by pyridoacridine alkaloids from a Cystodytes sp. ascidian: a mechanism for the apparent intercalator-induced inhibition of topoisomerase II. J. Med. Chem. 37, 3819-3827.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 3819-3827
-
-
McDonald, L.A.1
Eldredge, G.S.2
Barrows, L.R.3
Ireland, C.M.4
-
30
-
-
0024804442
-
Sensitivity of Chinese hamster ovary mutants defective in DNA double strand break repair to topoisomerase II inhibitors
-
Jeggo, P. A., Caldecott, C., Pidsley, S., and Banks, G. R. (1989) Sensitivity of Chinese hamster ovary mutants defective in DNA double strand break repair to topoisomerase II inhibitors. Cancer Res. 49, 7057-7063.
-
(1989)
Cancer Res.
, vol.49
, pp. 7057-7063
-
-
Jeggo, P.A.1
Caldecott, C.2
Pidsley, S.3
Banks, G.R.4
-
31
-
-
0023130372
-
Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing
-
Carmichael, J., DeGraff, W. G., Gadzar, A. F., Minna, J. D., and Mitchell, J. B. (1987) Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res. 47, 936-942.
-
(1987)
Cancer Res.
, vol.47
, pp. 936-942
-
-
Carmichael, J.1
DeGraff, W.G.2
Gadzar, A.F.3
Minna, J.D.4
Mitchell, J.B.5
-
32
-
-
0014481378
-
Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues
-
Tietze, F. (1969) Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal. Biochem, 27, 502-522.
-
(1969)
Anal. Biochem.
, vol.27
, pp. 502-522
-
-
Tietze, F.1
-
33
-
-
0026656831
-
Modulation of glutathione levels in CHO cells: Effects of oxygen concentration and prior exposure to hypoxia
-
Lin, A. A., and Miller, W. M. (1992) Modulation of glutathione levels in CHO cells: effects of oxygen concentration and prior exposure to hypoxia. Ann. N. Y. Acad. Sci. 665, 117-126.
-
(1992)
Ann. N. Y. Acad. Sci.
, vol.665
, pp. 117-126
-
-
Lin, A.A.1
Miller, W.M.2
-
34
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
35
-
-
0028656498
-
RT-PCR assay for heme oxygenase-1 and heme oxygenase-2: A sensitive method to estimate cellular oxidative damage
-
Kutty, R. K., Kutty, G., Nagineni, C. N., Hooks, J. J., Chader, G. J, and Wiggert, B. (1994) RT-PCR assay for heme oxygenase-1 and heme oxygenase-2: a sensitive method to estimate cellular oxidative damage. Ann. N. Y. Acad. Sci. 738, 427-430.
-
(1994)
Ann. N. Y. Acad. Sci.
, vol.738
, pp. 427-430
-
-
Kutty, R.K.1
Kutty, G.2
Nagineni, C.N.3
Hooks, J.J.4
Chader, G.J.5
Wiggert, B.6
-
36
-
-
0030779114
-
Expression of oxidative stress-responsive genes and cytokine genes during caerulin-induced acute pancreatitis
-
Fu, K., Sarras, M. P., De Lisle, R. C., and Andrews, G. K. (1997) Expression of oxidative stress -responsive genes and cytokine genes during caerulin-induced acute pancreatitis. Am. J. Physiol. 273, G696-G704.
-
(1997)
Am. J. Physiol.
, vol.273
-
-
Fu, K.1
Sarras, M.P.2
De Lisle, R.C.3
Andrews, G.K.4
-
37
-
-
0023713873
-
Oxidant-induced DNA damage of target cells
-
Schraufstatter, I., Hyslop, P. A., Jackson, J. H., and Cochrane, C. G. (1988) Oxidant-induced DNA damage of target cells. J. Clin. Invest. 82, 1040-1050.
-
(1988)
J. Clin. Invest.
, vol.82
, pp. 1040-1050
-
-
Schraufstatter, I.1
Hyslop, P.A.2
Jackson, J.H.3
Cochrane, C.G.4
-
38
-
-
0031439957
-
Oxidative DNA cleavage by the antitumor antibiotic leinamycin and simple 1,2-dithiolan-3-one 1-oxides: Evidence for thiol-dependent conversion of molecular oxygen to DNA-cleaving oxygen radicals mediated by polysulfides
-
Mitra, K., Kim, W., Daniels, J. S., and Gates, K. S. (1997) Oxidative DNA cleavage by the antitumor antibiotic leinamycin and simple 1,2-dithiolan-3-one 1-oxides: Evidence for thiol-dependent conversion of molecular oxygen to DNA-cleaving oxygen radicals mediated by polysulfides. J. Am. Chem. Soc. 119, 11691-11692.
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 11691-11692
-
-
Mitra, K.1
Kim, W.2
Daniels, J.S.3
Gates, K.S.4
-
39
-
-
0032956510
-
Pyrroloquinoline and pyridoacridine alkaloids from marine sources
-
Ding, Q., Chicak, K., and Lown, J. W. (1999) Pyrroloquinoline and pyridoacridine alkaloids from marine sources. Curr. Med. Chem. 6, 1-27.
-
(1999)
Curr. Med. Chem.
, vol.6
, pp. 1-27
-
-
Ding, Q.1
Chicak, K.2
Lown, J.W.3
-
40
-
-
0035846899
-
XRCC1 Stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair
-
Whitehouse, C. J., Taylor, R. M., Thistlethwaite, A., Zhang, H., Busheri, F. K., Lasko, D. D., Weinfeld, M., and Caldecott, K. W. (2001) XRCC1 Stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair. Cell 104, 107-117.
-
(2001)
Cell
, vol.104
, pp. 107-117
-
-
Whitehouse, C.J.1
Taylor, R.M.2
Thistlethwaite, A.3
Zhang, H.4
Busheri, F.K.5
Lasko, D.D.6
Weinfeld, M.7
Caldecott, K.W.8
-
41
-
-
0025913248
-
Varacin, a novel antifungal polysulfide from Lissoclinum vareau
-
Davidson, B. S., Molinski, T. F., Barrows, L. R., and Ireland, C. M. (1991) Varacin, a novel antifungal polysulfide from Lissoclinum vareau. J. Am. Chem. Soc. 113, 4709-4710.
-
(1991)
J. Am. Chem. Soc.
, vol.113
, pp. 4709-4710
-
-
Davidson, B.S.1
Molinski, T.F.2
Barrows, L.R.3
Ireland, C.M.4
-
42
-
-
0032478161
-
DNA cleavage by 7-methylbenzopentathiepin: A simple analog of the antitumor antibiotic varacin
-
Chatterji, T., and Gates, K. S. (1998) DNA cleavage by 7-methylbenzopentathiepin: a simple analog of the antitumor antibiotic varacin. Bioorg. Med. Chem. Lett. 8, 535-538.
-
(1998)
Bioorg. Med. Chem. Lett.
, vol.8
, pp. 535-538
-
-
Chatterji, T.1
Gates, K.S.2
-
43
-
-
0031927973
-
The CHO XRCC1 mutant, EM9, deficient in DNA ligase III activity, exhibits hypersensitivity to camptothecin independent of DNA replication
-
Barrows, L. R., Holden, J. A., Anderson, M., and D'Arpa, P. (1998) The CHO XRCC1 mutant, EM9, deficient in DNA ligase III activity, exhibits hypersensitivity to camptothecin independent of DNA replication. Mutat. Res. 408, 103-110.
-
(1998)
Mutat. Res.
, vol.408
, pp. 103-110
-
-
Barrows, L.R.1
Holden, J.A.2
Anderson, M.3
D'Arpa, P.4
-
44
-
-
0035093737
-
DNA double-strand breaks: Signaling, repair and the cancer connection
-
Khana, K. K., and Jackson, S. P. (2001) DNA double-strand breaks: signaling, repair and the cancer connection. Nat. Genet. 27, 247-254.
-
(2001)
Nat. Genet.
, vol.27
, pp. 247-254
-
-
Khana, K.K.1
Jackson, S.P.2
-
45
-
-
0001852317
-
Human tumor xenograft models in NCI drug development
-
Teicher, B., Ed., Humana Press Inc., New Jersey
-
Plowman, J., Dykes, D. J., Hollingshead, M., Simpson-Herren, L., and Alley, M. C. (1994) Human tumor xenograft models in NCI drug development. In Anticancer Drug Development Guide: Preclinical Screening, Clinical Trials and Approval (Teicher, B., Ed.) pp 101-125, Humana Press Inc., New Jersey.
-
(1994)
Anticancer Drug Development Guide: Preclinical Screening, Clinical Trials and Approval
, pp. 101-125
-
-
Plowman, J.1
Dykes, D.J.2
Hollingshead, M.3
Simpson-Herren, L.4
Alley, M.C.5
|