Deadly decisions: The role of genes regulating programmed cell death in human preimplantation embryo development

Reproduction

Volumn 128, Issue 3, 2004, Pages 281-291

  Jurisicova, Andrea ^a,b   Acton, Beth M ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BH3 PROTEIN; CASPASE; ENDONUCLEASE; HEAT SHOCK TRANSCRIPTION FACTOR 1; INHIBITOR OF APOPTOSIS PROTEIN; MITOCHONDRIAL PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MCL 1; PROTEIN P53; SURVIVIN;

APOPTOSIS; CELL DIFFERENTIATION; CELL FATE; CELL INTERACTION; CELL SURVIVAL; CELLULAR DISTRIBUTION; CULTURE MEDIUM; DEVELOPMENTAL STAGE; DNA DAMAGE; EMBRYO; EMBRYO CULTURE; EMBRYO DEATH; EMBRYO DEVELOPMENT; FEMALE; FERTILIZATION IN VITRO; GENE EXPRESSION; GENETIC REGULATION; GENETIC TRANSCRIPTION; HUMAN; MEDICAL DECISION MAKING; METABOLIC REGULATION; MOUSE; MOUSE MUTANT; NONHUMAN; OOCYTE DEVELOPMENT; OUTCOMES RESEARCH; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN FAMILY; REVIEW;

ANIMALS; APOPTOSIS; BLASTOCYST; EMBRYO CULTURE TECHNIQUES; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MALE; MICE; MICE, KNOCKOUT; MODELS, ANIMAL; OOCYTES; PREGNANCY; REPRODUCTIVE TECHNIQUES, ASSISTED;

ANIMALIA;

EID: 4544304070     PISSN: 14701626     EISSN: None     Source Type: Journal    
DOI: 10.1530/rep.1.00241     Document Type: Review

References (92)

1. Acton BM, Jurisicova A, Ahmady A, Xu J, Perez GI & Casper RF 2001 Microinjection of mitochondrial fractions into FVB oocytes influences in vitro survival rates. Proceedings of the 34th Annual Meeting for the Society for the Study of Reproduction, Ottawa, Ontario, Canada. Biology of Reproduction 64 (Suppl 1) 279.
2. Acton BM, Jurisicova A, Jurisica I & Casper RF 2004 Alterations in mitochondrial membrane potential during preimplantation stages of mouse and human embryo development. Molecular Human Reproduction 10 23-32.
3. Adams JM & Cory S 1998 The Bcl-2 protein family: arbiters of cell survival. Science 281 1322-1326.
4. Adams JM & Cory S 2001 Life-or-death decisions by the Bcl-2 protein family. Trends in Biochemical Sciences 26 61-66.
5. Alikani M, Cohen J, Tomkin G, Garrisi GJ, Mack C & Scott RT 1999 Human embryo fragmentation in vitro and its implications for pregnancy and implantation. Fertility and Sterility 71 836-842.
6. Altieri DC 2003 Survivin in apoptosis control and cell cycle regulation in cancer. Progress in Cell Cycle Research 5 447-452.
7. Antczak M & Van Blerkom J 1999 Temporal and spatial aspects of fragmentation in early human embryos: possible effects on developmental competence and association with the differential elimination of regulatory proteins from polarized domains. Human Reproduction 14 429-447.
8. Antonsson B & Martinou JC 2000 The Bcl-2 protein family. Experimental Cell Research 256 50-57.
9. Bongso A, Ng SC, Lim J, Fong CY & Ratnam S 1991 Preimplantation genetics: chromosomes of fragmented human embryos. Fertility and Sterility 56 66-70.
10. Brewster JL, Martin SL, Toms J, Goss D, Wang K, Zachrone K, Davis A, Carlson G, Hood L & Coffin JD 2000 Deletion of Dad1 in mice induces an apoptosis-associated embryonic death. Genesis 26 271-278.
11. Bruey JM, Ducasse C, Bonniaud P, Ravagnan L, Susin SA, Diaz-Latoud C, Gurbuxani S, Arrigo AP, Kroemer G, Solary E & Garrido C 2000 Hsp27 negatively regulates cell death by interacting with cytochrome c. Nature Cell Biology 2 645-652.
12. Capano M & Crompton M 2002 Biphasic translocation of Bax to mitochondria. Biochemical Journal 367 169-178.
13. Centers for Disease Control and Prevention DoRH 2003 2001 Assisted Reproductive Technology Success Rates. http://www.cdc.gov/reproductivehealth/ART01/PDFD/ART2001.pdf.
14. Christians E, Michel E & Renard JP 1997 Developmental control of heat shock and chaperone gene expression. Hsp 70 genes and heat shock factors during preimplantation phase of mouse development. Cellular and Molecular Life Science 53 168-178.
15. Christians E, Davis AA, Thomas SD & Benjamin IJ 2000 Maternal effect of Hsf1 on reproductive success. Nature 407 693-694.
16. Cooper LF, Uoshima K & Guo Z 2000 Transcriptional regulation involving the intronic heat shock element of the rat hsp27 gene. Biochimica et Biophysica Acta 1490 348-354.
17. Desagher S & Martinou JC 2000 Mitochondria as the central control point of apoptosis. Trends in Cell Biology 10 369-377.
18. Devreker F & Englert Y 2000 In vitro development and metabolism of the human embryo up to the blastocyst stage. European Journal of Obstetrics, Gynecology, and Reproductive Biology 92 51-56.
19. Donovan M & Cotter TG 2004 Control of mitochondrial integrity by Bcl-2 family members and caspase-independent cell death. Biochimica et Biophysica Acta 1644 133-147.
20. Earnshaw WC, Martins LM & Kaufmann SH 1999 Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annual Review of Biochemistry 68 383-424.
21. Ebner T, Yaman C, Moser M, Sommergruber M, Polz W & Tews G 2001 Embryo fragmentation in vitro and its impact on treatment and pregnancy outcome. Fertility and Sterility 76 281-285.
22. Exley GE, Tang C, McElhinny AS & Warner CM 1999 Expression of caspase and BCL-2 apoptotic family members in mouse preimplantation embryos. Biology of Reproduction 61 231-239.
23. Fridman JS, Rehemtulla A, Hofmann A, Blau HM & Maybaum J 1998 Expression of Bcl-XS alters cytokinetics and decreases clonogenic survival in K12 rat colon carcinoma cells. Oncogene 17 2981-2991.
24. Gandolfi TA & Gandolfi F 2001 The maternal legacy to the embryo: cytoplasmic components and their effects on early development. Theriogenology 55 1255-1276.
25. Gjorret JO, Knijn HM, Dieleman SJ, Avery B, Larsson LI & Maddox-Hyttel P 2003 Chronology of apoptosis in bovine embryos produced in vivo and in vitro. Biology of Reproduction 69 1193-1200.
26. Goddard MJ & Pratt HP 1983 Control of events during early cleavage of the mouse embryo: an analysis of the '2-cell block'. Journal of Embryology and Experimental Morphology 73 111-133.
27. Gozuacik D & Kimchi A 2004 Autophagy as a cell death and tumor suppressor mechanism. Oncogene 23 2891-2906.
28. Green DR & Reed JC 1998 Mitochondria and apoptosis. Science 281 1309-1312.
29. Hardy K 1999 Apoptosis in the human embryo. Reviews of Reproduction 4 125-134.
30. Hardy K, Spanos S, Becker D, Iannelli P, Winston RM & Stark J 2001 From cell death to embryo arrest: mathematical models of human preimplantation embryo development. PNAS 98 1655-1660.
31. Hengartner MO 2000 The biochemistry of apoptosis. Nature 407 770-776.
32. Hnida C, Engenheiro E & Ziebe S 2004 Computer-controlled, multi-level, morphometric analysis of blastomere size as biomarker of fragmentation and multinuclearity in human embryos. Human Reproduction 19 288-293.
33. Jain T, Missmer SA & Hornstein MD 2004 Trends in embryo-transfer practice and in outcomes of the use of assisted reproductive technology in the United States. New England Journal of Medicine 350 1639-1645.
34. Jurisicova A, Varmuza S & Casper RF 1996 Programmed cell death and human embryo fragmentation. Molecular Human Reproduction 2 93-98.
35. Jurisicova A, Latham KE, Casper RF & Varmuza SL 1998a Expression and regulation of genes associated with cell death during murine preimplantation embryo development. Molecular Reproduction and Development 51 243-253.
36. Jurisicova A, Rogers I, Fasciani A, Casper RF & Varmuza S 1998b Effect of maternal age and conditions of fertilization on programmed cell death during murine preimplantation embryo development. Molecular Human Reproduction 4 139-145.
37. Jurisicova A, Casper RF & Tilly J 2001 Bcl-x isoforms differentially affect preimplantation embryo development. In Cold Spring Harbor Autumn Symposium on Programmed Cell Death, p 119. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
38. Jurisicova A, Perez G, Acton B, Casper RF & Tilly J 2002 Oocyte survival is controlled by age related changes in death regulatory pathways. Proceedings of the 49th Annual Meeting of Society for Gynecological Investigation, Los Angeles, CA, USA. Journal for the Society for Gynecologic Investigation 9 (Suppl) 66A.
39. Jurisicova A, Antenos M, Varmuza S, Tilly JL & Casper RF 2003 Expression of apoptosis-related genes during human preimplantation embryo development: potential roles for the Harakiri gene product and Caspase-3 in blastomere fragmentation. Molecular Human Reproduction 9 133-141.
40. Kawamura K, Fukuda J, Kodama H, Kumagai J, Kumagai A & Tanaka T 2001 Expression of Fas and Fas ligand mRNA in rat and human preimplantation embryos. Molecular Human Reproduction 7 431-436.
41. Kawamura K, Sato N, Fukuda J, Kodama H, Kumagai J, Tanikawa H, Shimizu Y & Tanaka T 2003 Survivin acts as an antiapoptotic factor during the development of mouse preimplantation embryos. Developmental Biology 256 331-341.
42. Keim AL, Chi MM & Moley KH 2001 Hyperglycemia-induced apoptotic cell death in the mouse blastocyst is dependent on expression of p53. Molecular Reproduction and Development 60 214-224.
43. Kobayashi K, Hatano M, Otaki M, Ogasawara T & Tokuhisa T 1999 Expression of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation. PNAS 96 1457-1462.
44. Levine B & Klionsky DJ 2004 Development by self-digestion; molecular mechanisms and biological functions of autophagy. Developmental Cell 6 463-477.
45. Li LY, Luo X & Wang X 2001 Endonuclease G is an apoptotic DNase when released from mitochondria. Nature 412 95-99.
46. Lindenboim L, Yuan J & Stein R 2000 Bcl-xS and Bax induce different apoptotic pathways in PC12 cells. Oncogene 19 1783-1793.
47. Liu HC, He ZY, Mele CA, Veeck LL, Davis O & Rosenwaks Z 2000 Expression of apoptosis-related genes in human oocytes and embryos. Journal of Assisted Reproduction and Genetics 17 521-533.
48. Lorenzo HK & Susin SA 2004 Mitochondrial effectors in caspase-independent cell death. FEBS Letters 557 14-20.
49. Majno G & Joris I 1995 Apoptosis, oncosis, and necrosis. An overview of cell death. American Journal of Pathology 146 3-15.
50. Makishima T, Yoshimi M, Komiyama S, Hara N & Nishimoto T 2000 A subunit of the mammalian oligosaccharyltransferase, DAD1, interacts with Mcl-1, one of the bcl-2 protein family. Journal of Biochemistry 128 399-405.
51. Martinez F, Rienzi L, Iacobelli M, Ubaldi F, Mendoza C, Greco E & Tesarik J 2002 Caspase activity in preimplantation human embryos is not associated with apoptosis. Human Reproduction 17 1584-1590.
52. Metcalfe AD, Bloor DJ, Lieberman BA, Kimber SJ & Brison DR 2003 Amplification of representative cDNA pools from single human oocytes and pronucleate embryos. Molecular Reproduction and Development 65 1-8.
53. Metcalfe AD, Hunter HR, Bloor DJ, Lieberman BA, Picton HM, Leese HJ, Kimber SJ & Brison DR 2004 Expression of 11 members of the BCL-2 family of apoptosis regulatory molecules during human preimplantation embryo development and fragmentation. Molecular Reproduction and Development 68 35-50.
54. Moley KH 2001 Hyperglycemia and apoptosis: mechanisms for congenital malformations and pregnancy loss in diabetic women. Trends in Endocrinology and Metabolism 12 78-82.
55. Moley KH, Chi MM, Knudson CM, Korsmeyer SJ & Mueckler MM 1998 Hyperglycemia induces apoptosis in pre-implantation embryos through cell death effector pathways. Nature Medicine 4 1421-1424.
56. Muggleton-Harris AL & Brown JJ 1988 Cytoplasmic factors influence mitochondrial reorganization and resumption of cleavage during culture of early mouse embryos. Human Reproduction 3 1020-1028.
57. Munne S, Alikani M, Tomkin G, Grifo J & Cohen J 1995 Embryo morphology, developmental rates, and maternal age are correlated with chromosome abnormalities. Fertility and Sterility 64 382-391.
58. Nishii K, Tsuzuki T, Kumai M, Takeda N, Koga H, Aizawa S, Nishimoto T & Shibata Y 1999 Abnormalities of developmental cell death in Dad1-deficient mice. Genes to Cells 4 243-252.
59. Ohashi A, Minami N & Imai H 2001 Nuclear accumulation of cyclin B1 in mouse two-cell embryos is controlled by the activation of Cdc2. Biology of Reproduction 65 1195-1200.
60. Okada H, Bakal C, Shahinian A, Elia A, Wakeham A, Suh WK, Duncan GS, Ciofani M, Rottapel R, Zuniga-Pflucker JC & Mak TW 2004 Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death. Journal of Experimental Medicine 199 399-410.
61. Perez GI, Tao XJ & Tilly JL 1999 Fragmentation and death (a.k.a. apoptosis) of ovulated oocytes. Molecular Human Reproduction 5 414-420.
62. Pierce GB, Lewellyn AL & Parchment RE 1989 Mechanism of programmed cell death in the blastocyst. PNAS 86 3654-3658.
63. Pierce GB, Parchment RE & Lewellyn AL 1991 Hydrogen peroxide as a mediator of programmed cell death in the blastocyst. Differentiation 46 181-186.
64. Print CG, Loveland KL, Gibson L, Meehan T, Stylianou A, Wreford N, de Kretser D, Metcalf D, Kontgen F, Adams JM & Cory S 1998 Apoptosis regulator bcl-w is essential for spermatogenesis but appears otherwise redundant. PNAS 95 12424-12431.
65. Puthalakath H & Strasser A 2002 Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins. Cell Death and Differentiation 9 505-512.
66. Ravagnan L, Gurbuxani S, Susin SA, Maisse C, Daugas E, Zamzami N, Mak T, Jaattela M, Penninger JM, Garrido C & Kroemer G 2001 Heat-shock protein 70 antagonizes apoptosis-inducing factor. Nature Cell Biology 3 839-843.
67. Rinkenberger JL, Horning S, Klocke B, Roth K & Korsmeyer SJ 2000 Mcl-1 deficiency results in peri-implantation embryonic lethality. Genes and Development 14 23-27.
68. Ross AJ, Waymire KG, Moss JE, Parlow AF, Skinner MK, Russell LD & MacGregor GR 1998 Testicular degeneration in Bclw-deficient mice. Nature Genetics 18 251-256.
69. Sanjay A, Fu J & Kreibich G 1998 DAD1 is required for the function and the structural integrity of the oligosaccharyltransferase complex. Journal of Biological Chemistry 273 26094-26099.
70. Sistonen L, Sarge KD & Morimoto RI 1994 Human heat shock factors 1 and 2 are differentially activated and can synergistically induce hsp70 gene transcription. Molecular and Cellular Biology 14 2087-2099.
71. Spanos S, Rice S, Karagiannis P, Taylor D, Becker DL, Winston RM & Hardy K 2002 Caspase activity and expression of cell death genes during development of human preimplantation embryos. Reproduction 124 353-363.
72. Takayama S, Reed JC & Homma S 2003 Heat-shock proteins as regulators of apoptosis. Oncogene 22 9041-9047.
73. Telford NA, Watson AJ & Schultz GA 1990 Transition from maternal to embryonic control in early mammalian development: a comparison of several species. Molecular Reproduction and Development 26 90-100.
74. Tilly JL 2001 Commuting the death sentence: how oocytes strive to survive. Nature Reviews. Molecular Cell Biology 2 838-848.
75. Tolkovsky AM, Xue L, Fletcher GC & Borutaite V 2002 Mitochondrial disappearance from cells: a clue to the role of autophagy in programmed cell death and disease? Biochimie 84 233-240.
76. Tong ZB, Gold L, Pfeifer KE, Dorward H, Lee E, Bondy CA, Dean J & Nelson LM 2000a Mater, a maternal effect gene required for early embryonic development in mice. Nature Genetics 26 267-268.
77. Tong ZB, Nelson LM & Dean J 2000b Mater encodes a maternal protein in mice with a leucine-rich repeat domain homologous to porcine ribonuclease inhibitor. Mammalian Genome 11 281-287.
78. Tong ZB, Gold L, De Pol A, Vanevski K, Dorward H, Sena P, Palumbo C, Bondy CA & Nelson LM 2004 Developmental expression and subcellular localization of mouse Mater, an oocyte-specific protein essential for early development. Endocrinology 145 1427-1434.
79. Trounson A & Bongso A 1996 Fertilization and development in humans. Current Topics in Developmental Biology 32 59-101.
80. Tschopp J, Martinon F & Burns K 2003 NALPs: a novel protein family involved in inflammation. Nature Reviews. Molecular Cell Biology 4 95-104.
81. Uren AG, Wong L, Pakusch M, Fowler KJ, Burrows FJ, Vaux DL & Choo KH 2000 Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype. Current Biology 10 1319-1328.
82. Van Blerkom J, Davis P & Alexander S 2001 A microscopic and biochemical study of fragmentation phenotypes in stage-appropriate human embryos. Human Reproduction 16 719-729.
83. Van Blerkom J, Davis P, Mathwig V & Alexander S 2002 Domains of high-polarized and low-polarized mitochondria may occur in mouse and human oocytes and early embryos. Human Reproduction 17 393-406.
84. Vaux DL & Korsmeyer SJ 1999 Cell death in development. Cell 96 245-254.
85. Vaux DL & Silke J 2003a HtrA2/Omi, a sheep in wolf's clothing. Cell 115 251-253.
86. Vaux DL & Silke J 2003b Mammalian mitochondrial IAP binding proteins. Biochemical and Biophysical Research Communications 304 499-504.
87. Wu X, Viveiros MM, Eppig JJ, Bai Y, Fitzpatrick SL & Matzuk MM 2003 Zygote arrest 1 (Zar1) is a novel maternal-effect gene critical for the oocyte-to-embryo transition. Nature Genetics 33 187-191.
88. Xu J, Cheung T, Chan ST, Ho P & Yeung WS 2001 The incidence of cytoplasmic fragmentation in mouse embryos in vitro is not affected by inhibition of caspase activity. Fertility and Sterility 75 986-991.
89. Yang HW, Hwang KJ, Kwon HC, Kim HS, Choi KW & Oh KS 1998 Detection of reactive oxygen species (ROS) and apoptosis in human fragmented embryos. Human Reproduction 13 998-1002.
90. Zha J, Harada H, Yang E, Jockel J & Korsmeyer SJ 1996 Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-13-3 not BCL-X(L). Cell 87 619-628.
91. Zhang J, Dong M, Li L, Fan Y, Pathre P, Dong J, Lou D, Wells JM, Olivares-Villagomez D, Van Kaer L, Wang X & Xu M 2003 Endonuclease G is required for early embryogenesis and normal apoptosis in mice. PNAS 100 15782-15787.
92. Ziebe S, Petersen K, Lindenberg S, Andersen AG, Gabrielsen A & Andersen AN 1997 Embryo morphology or cleavage stage: how to select the best embryos for transfer after in-vitro fertilization. Human Reproduction 12 1545-1549.