Effects of the m1 agonist xanomeline on processing of human β-amyloid precursor protein (FAD, Swedish mutant) transfected into Chinese hamster ovary-m1 cells

Biochemical and Biophysical Research Communications

Volumn 244, Issue 1, 1998, Pages 156-160

  Delapp, Neil ^a   Wu, Su ^a   Belagaje, Rama ^a   Johnstone, Ed ^a   Little, Shelia ^a   Shannon, Harlan ^a   Bymaster, Frank ^a   Calligaro, David ^a   Mitch, Charles ^a   Whitesitt, Celia ^a   Ward, John ^a   Sheardown, Malcolm ^b   Fink Jensen, Anders ^b   Jeppesen, Lone ^b   Thomsen, Christian ^b   Sauerberg, Per ^b  

^a ELI LILLY AND COMPANY   (United States)

^b NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CARBACHOL; COMPLEMENTARY DNA; MUSCARINIC M1 RECEPTOR; XANOMELINE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CHO CELL; EXPRESSION VECTOR; GENE MUTATION; GENETIC TRANSFECTION; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; CUCUMBER MOSAIC VIRUS; MAMMALIA;

EID: 0032489322     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1998.8235     Document Type: Article

References (25)

1. Terry R. D. Brain. 311:1963;528-530.
2. Kidd M. J. Neuropathol. Exp. Neurol. 87:1964;307.
3. Haass C., Selkoe D. J. Cell. 75:1993;1039-1042.
4. Sisodia S. S., Koo E. H., Beyreuther K., Unterbeck A., Price D. L. Science. 248:1990;492-495.
5. Haass C., Schlossmacher M. G., Hung A. Y., Vigo-Pelfry C., Melon A., Ostaszewski B. L., Lieberburg I., Koo E. H., Schenk D., Teplow D. B., Selkoe D. J. Nature. 359:1992;322-324.
6. Cai K. D., Golde T. E., Younkin S. G. Science. 259:1993;514-516.
7. Murrell M., Farlow M., Ghetti B., Benson M. D. Science. 254:1991;97-99.
8. Estus E., Golde T. E., Kunistuta T., Blades D., Lowery D., Eisen M., Usiah M., Qu X., Tabria T., Greenberg B. D., Younkin S. G. Science. 255:1992;726-728.
9. Forray C., El-Fakahany E. E. Mol. Pharmacol. 37:1990;893-902.
10. Nitsch R. M., Slack B. E., Wurtman R. J., Growdon J. H. Science. 258:1992;304-307.
11. Hung A. Y., Haass C., Nitsch R. M., Qiu W. Q., Citron M., Wurtman R. J., Growdon J. H., Selkoe D. J. J. Biol. Chem. 268:1993;22959-22962.
12. Shannon H. E., Bymaster F. P., Calligaro D. O., Greenwood B., Mitch C. H., Sawyer B. D., Ward J. S., Wong D. T., Olesen P. H., Sheardown M. J., Swedberg M. D. B., Suzdak P. D., Sauerberg P. J. Pharmacol. Exp. Ther. 269:1994;271-281.
13. Bymaster F. P., Wong D. T., Mitch C. H., Ward J. S., Calligaro D. O., Shoepp D. D., Shannon H. E., Sheardown M. J., Olesen P. H., Suzdak P. D., Swedberg M. B. D., Sauerberg P. J. Pharmacol. Exp. Ther. 269:1994;282-289.
14. Sauerberg P., Olesen P. H., Nielsen S., Trependahl S., Sheardown M. J., Honore T., Mitch C. H., Ward J. S., Pike A. J., Bymaster F. P., Sawyer B. D., Shannon H. E. J. Med. Chem. 35:1992;2274-2283.
15. Eckols K., Bymaster F. P., Mitch C. H., Shannon H. E., Ward J. S., DeLapp N. W. Life Sci. 57:1995;1183-1190.
16. Kang J., Lemaire H. G., Unterbeck A., Salbaum J. M., Masters C. L., Greschik K. H., Muthaup G., Beyreuther K., Muller-Hill B. Nature. 325:1987;733-736.
17. Lowry O. H., Rosebrough N. J., Farr A. L., Randall R. J. J. Biol. Chem. 193:1951;265-275.
18. Haring R., Gurwitz D., Barg J., Pinkas-Kramarski R., Heldman E., Pittel Z., Wengien A., Meshulam H., Marciano D., Karton Y., Fisher A. Biochem. Biophys. Res. Commun. 203:1994;652-658.
19. Pittel Z., Heldman E., Barg J., Haring R., Fisher A. Brain Res. 742:1996;299-304.
20. Farber S. A., Nitsch R. M., Schultz J. G., Wurtman R. J. J. Neurosci. 15:1995;7442-7451.
21. Davis R. E., Doyle P. D., Carrol R. T., Emmerling M. R., Jaen J. Arzeim-Forsch. 45:1995;425-431.
22. Slunt H. H., Thinakaran G., Van Koch C., Lo A. C. Y., Tanzi R. E., Sisodia S. S. J. Biol. Chem. 269:1994;2637-2644.
23. Kim K. S., Wen G. Y., Bancher C., Chen C. M. J., Sapienza V. J., Hong H., Wisniewski H. M. Biochem. Biophys. Res. Commun. 7:1990;113-122.
24. Johnstone E. M., Chaney M. O., Norris F. H., Pascual R., Little S. P. Mol. Brain Res. 10:1991;299-305.
25. Kim K. S., Miller D. L., Sapienza V. J., Chen C. M. J., Bai C., Grundke-Iqbal I., Currie J. R., Wisniewski H. M. Neurosci. Res. Commun. 2:1988;121-125.