Proteasomes cleave at multiple sites within polyglutamine tracts: Activation by PA28γ(K188E)

Journal of Biological Chemistry

Volumn 283, Issue 19, 2008, Pages 12919-12925

  Pratt, Gregory ^a   Rechsteiner, Martin ^a,b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; CHEMICAL ACTIVATION; CHROMATOGRAPHIC ANALYSIS; DEGRADATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MAMMALS; MASS SPECTROMETERS; MASS SPECTROMETRY; SIZE EXCLUSION CHROMATOGRAPHY; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS;

DEAMIDATION; GLUTAMIC ACIDS; HUMAN RED CELLS; HUNTINGTIN; LACTACYSTIN; MASS ACCURACIES; PEPTIDE HYDROLYSES; POLYGLUTAMINE; PROTEASOME; PROTEASOMES; SIZE EXCLUSIONS; SPECIFIC INHIBITORS; TOF MASS SPECTROMETRIES;

AMINO ACIDS;

EPOXOMICIN; FLUORESCEIN; GLUTAMIC ACID; GLUTAMINE; HUNTINGTIN; LACTACYSTIN; POLYGLUTAMINE; PROTEASOME; PROTEASOME INHIBITOR; SYNTHETIC PEPTIDE; TRINUCLEOTIDE; ION; PEPTIDE;

ARTICLE; DEAMINATION; ERYTHROCYTE; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; HYDROLYSIS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN STRUCTURE; CHEMISTRY; ENZYME ACTIVATION; GENETICS; MASS SPECTROMETRY; METABOLISM; MUTATION;

EUKARYOTA; MAMMALIA;

ENZYME ACTIVATION; HUMANS; IONS; MASS SPECTROMETRY; MUTATION; PEPTIDES; PROTEASOME ENDOPEPTIDASE COMPLEX;

EID: 45149115090     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M709347200     Document Type: Article

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