Modulation of Na+,K+ pumping and neurotransmitter uptake by β-amyloid

Neuroscience

Volumn 126, Issue 1, 2004, Pages 61-67

  Gu, Q B ^a,b   Zhao, J X ^a,b   Fei, J ^b   Schwarz, W ^a  

^a MAX PLANCK INSTITUTE OF BIOPHYSICS   (Germany)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

amyloid peptide; A ; AD; Alzheimer's disease; complementary RNA; cRNA; EAAC1; excitatory amino acid (glutamate) transporter 1; GABA transporter; GAT1; glutamate transporter; Na+,K+ ATPase; Xenopus oocyte

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID TRANSPORTER 1; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); AMYLOID BETA PROTEIN[1-42]; AMYLOID BETA PROTEIN[12-28]; AMYLOID BETA PROTEIN[25-35]; CARRIER PROTEIN; EXCITATORY AMINO ACID; GLUTAMIC ACID; PEPTIDE FRAGMENT; SODIUM ION; UNCLASSIFIED DRUG;

4 AMINOBUTYRIC ACID UPTAKE; AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; GENE EXPRESSION SYSTEM; INCUBATION TIME; ION TRANSPORT; MICROINJECTION; NEUROTOXICITY; NEUROTRANSMITTER UPTAKE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN FUNCTION; XENOPUS LAEVIS;

AMINO ACID TRANSPORT SYSTEM X-AG; AMYLOID BETA-PROTEIN; ANIMALS; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; EXCITATORY AMINO ACID TRANSPORTER 3; FEMALE; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GAMMA-AMINOBUTYRIC ACID; GLUTAMATE PLASMA MEMBRANE TRANSPORT PROTEINS; GLUTAMIC ACID; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; NA(+)-K(+)-EXCHANGING ATPASE; OOCYTES; PATCH-CLAMP TECHNIQUES; PEPTIDE FRAGMENTS; SYMPORTERS; XENOPUS LAEVIS;

EID: 2342446551     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2004.03.022     Document Type: Article

References (33)

1. Arispe N., Pollard H.B., Rojas E. Giant multilevel cation channels formed by Alzheimer disease amyloid beta protein. Proc Natl Acad Sci USA. 90:1993;10573-10577
2. Atwood C.S., Obrenovich M.E., Liu T., Chan H., Perry G., Smith M.A., Martins R.N. Amyloid-β A chameleon walking in two worlds: a review of trophic and toxic properties of amyloid-β Brain Res Rev. 43:2003;1-16
3. +-ATPase Tissue slices versus primary cultures. Brain Res Bul. 46:1998;423-427
4. Calabrese E.J. Amyloid β-peptide Biphasic dose responses. Crit Rev Toxicol. 31:2001;605-606
5. Chapman P.F., Falinska A.M., Knevett S.G., Ramsay M.F. Genes, models and Alzheimer's disease. Trends Genet. 17:2001;254-261
6. Coughlan C.M., Breen K.C. Factors influencing the processing and function of the amyloid β precursor protein A potential therapeutic target in alzheimer's disease? Pharmacol Ther. 86:2000;111-144
7. Duchen M.R., Surin A.M. On the roles of mitochondria and calcium in glutamate induced neurotoxicity in hippocampal neurons in culture. Biol Membr. 19:2003;4-16
8. 1-42 peptide alters the gating of human and mouse α-bungarotoxin-sensitive nicotinic receptors. J Physiol. 547:2003;147-157
9. + in Alzheimer's disease Difference from the age-matched control but similarity to the rat model. FEBS Lett. 531:2002;241-244
10. Khodorov, BI (2004) Glutamate-induced deregulation of calcium homeostasis and mitochondrial dysfunction in mammalian central neurones. Prog Biophys Mol Biol, in press.
11. Lauderback Ch M., Hackett J.M., Huang F.F., Keller J.N., Szweda L.I., Markesbery W.R., Butterfield D. The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain The role of aβ1-42. J Neurochem. 78:2001;413-416
12. +-dependent glutamate uptake. Life Sci. 65:1999;1977-1981
13. 2+-ATPase and some soluble enzymes related to energy metabolism in brains of patients with Alzheimer's disease. Neurosci Lett. 112:1990;338-342
14. Lin H., Bhatia R., Lal R. Amyloid β protein forms ion channels Implications for alzheimer's disease pathophysiology. FASEB J. 15:2001;2433-2444
15. +-ATPase activity in hippocampal-neurons. Brain Res. 756:1997;205-214
16. 1-42 peptide directly modulates nicotinic receptors in the rat hippocampal slice. J Neurosci. 21:2001;RC120
17. +]. J Membr Biol. 121:1991;177-187
18. Schmalzing G., Omay H., Kröner S., Gloor S., Appelhans H., Schwarz W. Up-regulation of sodium pump activity in Xenopus laevis oocytes by expression of heterologous β1 subunits of the sodium pump. Biochem J. 279:1991;329-336
19. Slotboom D.J., Konings W.N., Lolkema J.S. The structure of glutamate transporters shows channel-like features. FEBS Lett. 492:2001;183-186
20. 's disease and amyloid cascade hypothesis Ten years on. Curr Opin Pharmacol. 2:2002;87-92
21. Soomets U., Mahlapuu R., Tehranian R., Jarvet J., Karelson E., Zilmer M., Iverfeldt K., Zorko M., Graslund A., Langel U. Regulation of GTPase and adenylate cyclase activity by amyloid beta-peptide and its fragments in rat brain tissue. Brain Res. 850:1999;179-188
22. Steffgen J., Koepsell H., Schwarz W. Endogenous L-glutamate transport in oocytes of Xenopus laevis. Biochim Biophys Acta. 1066:1991;14-20
23. 2+ homeostasis requires re-evaluation. FEBS Lett. 431:1998;215-218
24. +-ATPase from mammalian kidneys and Xenopus oocytes by protein kinases Characterisation of the phosphorylation site for pk c. Cell Physiol Biochem. 7:1997;1-18
25. Vasilets L.A., Ohta T., Noguchi S., Kawamura M., Schwarz W. Voltage-dependent inhibition of the sodium pump by external sodium Species differences and possible role of the n-terminus of the α-subunit. Eur Biophys J. 21:1993;433-443
26. +] is regulated by voltage-dependent gating. J Biol Chem. 266:1991;16285-16288
27. +-ATPase. Biochim Biophys Acta. 1154:1993;201-222
28. Vergun O.V., Kellan J., Khodorov B.I., Duchen M.R. Glutamate-induced mitochondrial depolarisation and perturbation of calcium homeostasis in cultured rat hippocampal neurones. J Physiol. 519:1999;451-466
29. Wadiche J.I., Amara S.G., Kavanaugh M.P. Ion fluxes associated with excitatory amino acid transport. Neuron. 15:1995;721-728
30. Wang H.-Y., Lee D.H., Davis C.B., Shank R.P. Amyloid peptide Aβ(1-42) binds selectively and with picomolar affinity to α7 nicotinic acetylcholine receptors. J Neurochem. 75:2000;1155-1161
31. 1-42 binds to α7 nicotinic acetylcholine receptor with high affinity. J Biol Chem. 275:2000;5626-5632
32. 7 nicotinic acetylcholine receptor mediates β-amyloid peptide-induced tau protein phosphorylation. J Biol Chem. 278:2003;31547-31553
33. Yanker B.A., Duffy L.K., Kirschner D.A. Neurotrophic and neurotoxic effects of amyloid protein Reversal by tachykinin neuropeptides. Science. 250:1990;279-282