-
1
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
Braak H., Del Tredici K., Rueb U., de Vos R. A. I., Jansen Steur E. N. H. Braak E. (2003) Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol. Aging 24, 197 211.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.2
Rueb, U.3
De Vos, R.A.I.4
Jansen Steur, E.N.H.5
Braak, E.6
-
2
-
-
33846419768
-
Stanley Fahn lecture 2005: The staging procedure for the inclusion body pathology associated with sporadic Parkinson's disease reconsidered
-
Braak H., Bohl J. R., Mueller C. M., Rueb U., de Vos R. A. I. Del Tredici K. (2005) Stanley Fahn lecture 2005: the staging procedure for the inclusion body pathology associated with sporadic Parkinson's disease reconsidered. Mov. Disord. 21, 2042 2051.
-
(2005)
Mov. Disord.
, vol.21
, pp. 2042-2051
-
-
Braak, H.1
Bohl, J.R.2
Mueller, C.M.3
Rueb, U.4
De Vos, R.A.I.5
Del Tredici, K.6
-
3
-
-
32044453150
-
Pesticides and Parkinson's disease - Is there a link?
-
Brown T. P., Rumsby P. C., Capleton A. C., Rushton L. Levy L. S. (2005) Pesticides and Parkinson's disease - is there a link? Env. Health Persp. 114, 156 164.
-
(2005)
Env. Health Persp.
, vol.114
, pp. 156-164
-
-
Brown, T.P.1
Rumsby, P.C.2
Capleton, A.C.3
Rushton, L.4
Levy, L.S.5
-
4
-
-
0027446382
-
Electron spin resonance spin-trapping investigation into the effects of paraquat and desferrioxamine on hydroxyl radical generation during acute iron poisoning
-
Burkitt M. J., Kadiiska M. B., Hanna P. M., Jordan S. J. Mason R. P. (1993) Electron spin resonance spin-trapping investigation into the effects of paraquat and desferrioxamine on hydroxyl radical generation during acute iron poisoning. Mol. Pharmacol. 43, 257 263.
-
(1993)
Mol. Pharmacol.
, vol.43
, pp. 257-263
-
-
Burkitt, M.J.1
Kadiiska, M.B.2
Hanna, P.M.3
Jordan, S.J.4
Mason, R.P.5
-
5
-
-
0021288059
-
Paraquat: Model for oxidant-initiated toxicity
-
Bus J. S. Gibson J. E. (1984) Paraquat: model for oxidant-initiated toxicity. Environ. Health Perspect. 55, 37 46.
-
(1984)
Environ. Health Perspect.
, vol.55
, pp. 37-46
-
-
Bus, J.S.1
Gibson, J.E.2
-
6
-
-
0024392071
-
Synergistic interactions between NADPH-cytochrome P-450 reductase, paraquat, and iron in the generation of active oxygen radicals
-
Clejan L. Cederbaum A. I. (1989) Synergistic interactions between NADPH-cytochrome P-450 reductase, paraquat, and iron in the generation of active oxygen radicals. Biochem. Pharmacol. 38, 1779 1786.
-
(1989)
Biochem. Pharmacol.
, vol.38
, pp. 1779-1786
-
-
Clejan, L.1
Cederbaum, A.I.2
-
7
-
-
41249098254
-
Paraquat neurotoxicity is mediated by BNip3 and Noxa activation of Bak
-
Fei Q., McCormack A. L., Di Monte D. A. Ethell D. W. (2008) Paraquat neurotoxicity is mediated by BNip3 and Noxa activation of Bak. J. Biol. Chem. 283, 3357 3364.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 3357-3364
-
-
Fei, Q.1
McCormack, A.L.2
Di Monte, D.A.3
Ethell, D.W.4
-
8
-
-
0037115052
-
Catalysis of catechol oxidation by metal-dithiocarbamate complexes in pesticides
-
Fitsanakis V. A., Amarnath V., Moore J. T., Montine K. S., Zhang J. Montine T. J. (2002) Catalysis of catechol oxidation by metal-dithiocarbamate complexes in pesticides. Free Radic. Biol. Med. 33, 1714 1723.
-
(2002)
Free Radic. Biol. Med.
, vol.33
, pp. 1714-1723
-
-
Fitsanakis, V.A.1
Amarnath, V.2
Moore, J.T.3
Montine, K.S.4
Zhang, J.5
Montine, T.J.6
-
9
-
-
0030877835
-
Dopamine transporter is required for in vivo MPTP neurotoxicity: Evidence from mice lacking the transporter
-
Gainetdinov R. R., Fumagalli F., Jones S. R. Caron M. G. (1997) Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter. J. Neurochem. 69, 1322 1325.
-
(1997)
J. Neurochem.
, vol.69
, pp. 1322-1325
-
-
Gainetdinov, R.R.1
Fumagalli, F.2
Jones, S.R.3
Caron, M.G.4
-
10
-
-
0020680904
-
Chronic parkinsonism in humans due to a product of meperidine-analog synthesis
-
Langston J. W., Ballard P., Tetrud J. W. Irwin I. (1983) Chronic parkinsonism in humans due to a product of meperidine-analog synthesis. Science 219, 979 980.
-
(1983)
Science
, vol.219
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
11
-
-
0030878320
-
Environmental risk factors and Parkinson's disease: A case-control study in Taiwan
-
Liou H. H., Tsai M. C., Chen C. J., Jeng J. S., Chang Y. C., Chen S. Y. Chen R. C. (1997) Environmental risk factors and Parkinson's disease: a case-control study in Taiwan. Neurology 48, 1583 1588.
-
(1997)
Neurology
, vol.48
, pp. 1583-1588
-
-
Liou, H.H.1
Tsai, M.C.2
Chen, C.J.3
Jeng, J.S.4
Chang, Y.C.5
Chen, S.Y.6
Chen, R.C.7
-
12
-
-
18844373851
-
Role of oxidative stress in paraquat-induced dopaminergic cell degeneration
-
McCormack A. L., Atienza J. G., Johnston L. C., Andersen J. K., Vu S. DiMonte D. A. (2005) Role of oxidative stress in paraquat-induced dopaminergic cell degeneration. J. Neurochem. 93, 1030 1037.
-
(2005)
J. Neurochem.
, vol.93
, pp. 1030-1037
-
-
McCormack, A.L.1
Atienza, J.G.2
Johnston, L.C.3
Andersen, J.K.4
Vu, S.5
Dimonte, D.A.6
-
13
-
-
0033934857
-
Ethylenebisdithiocarbamate enhances MPTP-induced striatal dopamine depletion in mice
-
McGrew D. M., Irwin I. Langston J. W. (2000) Ethylenebisdithiocarbamate enhances MPTP-induced striatal dopamine depletion in mice. Neurotoxicology 21, 309 312.
-
(2000)
Neurotoxicology
, vol.21
, pp. 309-312
-
-
McGrew, D.M.1
Irwin, I.2
Langston, J.W.3
-
15
-
-
33947513592
-
Pesticide exposure exacerbates α-synucleinopathy in an A53T transgenic mouse model
-
Norris E. H., Uryu K., Leigth S., Giasson B. I., Trojanowski J. Q. Lee V. M.-Y. (2007) Pesticide exposure exacerbates α-synucleinopathy in an A53T transgenic mouse model. Am. J. Pathol. 170, 658 666.
-
(2007)
Am. J. Pathol.
, vol.170
, pp. 658-666
-
-
Norris, E.H.1
Uryu, K.2
Leigth, S.3
Giasson, B.I.4
Trojanowski, J.Q.5
Lee, V.M.-Y.6
-
16
-
-
3543011314
-
The herbicide paraquat induces dopaminergic nigral apoptosis through sustained activation of the JNK pathway
-
Peng J., Mao X. O., Stevenson F. F., Hsu M. Andersen J. K. (2004) The herbicide paraquat induces dopaminergic nigral apoptosis through sustained activation of the JNK pathway. J. Biol. Chem. 279, 32626 32632.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 32626-32632
-
-
Peng, J.1
Mao, X.O.2
Stevenson, F.F.3
Hsu, M.4
Andersen, J.K.5
-
17
-
-
23844483173
-
Superoxide dismutase/catalase mimetics are neuroprotective against selective paraquat-mediated dopaminergic neuron death in the substantial nigra: Implications for Parkinson disease
-
Peng J., Stevenson F. F., Doctrow S. R. Andersen J. K. (2005) Superoxide dismutase/catalase mimetics are neuroprotective against selective paraquat-mediated dopaminergic neuron death in the substantial nigra: implications for Parkinson disease. J. Biol. Chem. 280, 29194 29198.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 29194-29198
-
-
Peng, J.1
Stevenson, F.F.2
Doctrow, S.R.3
Andersen, J.K.4
-
18
-
-
30044442094
-
Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage
-
Perier C., Tieu K., Guégan C., Caspersen C., Jackson-Lewis V., Carelli V., Martinuzzi A., Hirano M., Przedborski S. Vila M. (2005) Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage. Proc. Natl Acad. Sci. USA 102, 19126 19131.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 19126-19131
-
-
Perier, C.1
Tieu, K.2
Guégan, C.3
Caspersen, C.4
Jackson-Lewis, V.5
Carelli, V.6
Martinuzzi, A.7
Hirano, M.8
Przedborski, S.9
Vila, M.10
-
19
-
-
34249947154
-
Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease
-
Perier C., Bové J., Wu D. C. et al. (2007) Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease. Proc. Natl Acad. Sci. USA 104, 8161 8166.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 8161-8166
-
-
Perier, C.1
Bové, J.2
Wu, D.C.3
-
20
-
-
0026583465
-
Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to MPTP neurotoxicity
-
Przedborski S., Jackson-Lewis V., Kostic V., Carlson E., Epstein C. J. Cadet J. L. (1992) Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to MPTP neurotoxicity. J. Neurosci. 12, 1658 1667.
-
(1992)
J. Neurosci.
, vol.12
, pp. 1658-1667
-
-
Przedborski, S.1
Jackson-Lewis, V.2
Kostic, V.3
Carlson, E.4
Epstein, C.J.5
Cadet, J.L.6
-
22
-
-
33845645902
-
+, and rotenone toxicity: Oxidation of thioredoxin and caspase-3 activation
-
+, and rotenone toxicity: oxidation of thioredoxin and caspase-3 activation. Toxicol. Sci. 95, 163 171.
-
(2007)
Toxicol. Sci.
, vol.95
, pp. 163-171
-
-
Ramachandiran, S.1
Hansen, J.M.2
Jones, D.P.3
Richardson, J.R.4
Miller, G.W.5
-
23
-
-
27644459974
-
Paraquat neurotoxicity is distinct from that of MPTP and rotenone
-
Richardson J. R., Quan Y., Sherer T. B., Greenamyre J. T. Miller G. W. (2005) Paraquat neurotoxicity is distinct from that of MPTP and rotenone. Toxicol. Sci. 88, 193 201.
-
(2005)
Toxicol. Sci.
, vol.88
, pp. 193-201
-
-
Richardson, J.R.1
Quan, Y.2
Sherer, T.B.3
Greenamyre, J.T.4
Miller, G.W.5
-
25
-
-
0033029823
-
CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons in vivo
-
Saporito M. S., Brown E. M., Miller M. S. Carswell S. (1999) CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons In vivo. J. Pharmacol. Exp. Ther. 288, 421 427.
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.288
, pp. 421-427
-
-
Saporito, M.S.1
Brown, E.M.2
Miller, M.S.3
Carswell, S.4
-
26
-
-
0033840581
-
MPTP activates c-Jun NH(2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo
-
Saporito M. S., Thomas B. A. Scott R. W. (2000) MPTP activates c-Jun NH(2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo. J. Neurochem. 75, 1200 1208.
-
(2000)
J. Neurochem.
, vol.75
, pp. 1200-1208
-
-
Saporito, M.S.1
Thomas, B.A.2
Scott, R.W.3
-
27
-
-
0026711037
-
Parkinson's disease and exposure to agricultural work and pesticide chemicals
-
Semchuk K. M., Love E. J. Lee R. G. (1992) Parkinson's disease and exposure to agricultural work and pesticide chemicals. Neurology 42, 1328 1335.
-
(1992)
Neurology
, vol.42
, pp. 1328-1335
-
-
Semchuk, K.M.1
Love, E.J.2
Lee, R.G.3
-
28
-
-
44649123410
-
Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist
-
[Epub ahead of print]
-
Simmons M. J., Fan G., Zong W. X., Degenhardt K., White E. Gélinas C. (2007) Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist. Oncogene [Epub ahead of print]
-
(2007)
Oncogene
-
-
Simmons, M.J.1
Fan, G.2
Zong, W.X.3
Degenhardt, K.4
White, E.5
Gélinas, C.6
-
29
-
-
0034637267
-
Potentiated and preferential effects of combined paraquat and maneb on nigrostriatal dopamine systems: Environmental risk factors for Parkinson's disease?
-
Thiruchelvam M., Brockel B. J., Richfield E. K., Baggs R. B. Cory-Slechta D. A. (2000a) Potentiated and preferential effects of combined paraquat and maneb on nigrostriatal dopamine systems: environmental risk factors for Parkinson's disease? Brain Res. 873, 225 234.
-
(2000)
Brain Res.
, vol.873
, pp. 225-234
-
-
Thiruchelvam, M.1
Brockel, B.J.2
Richfield, E.K.3
Baggs, R.B.4
Cory-Slechta, D.A.5
-
30
-
-
0034671469
-
The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: Implications for Parkinson's disease
-
Thiruchelvam M., Richfield E. K., Baggs R. B., Tank A. W. Cory-Slechta D. A. (2000b) The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease. J. Neurosci. 20, 9207 9214.
-
(2000)
J. Neurosci.
, vol.20
, pp. 9207-9214
-
-
Thiruchelvam, M.1
Richfield, E.K.2
Baggs, R.B.3
Tank, A.W.4
Cory-Slechta, D.A.5
-
31
-
-
20444471551
-
Overexpression of superoxide dismutase or glutathione peroxidase protects against the paraquat + maneb-induced Parkinson disease phenotype
-
Thiruchelvam M., Prokopenko O., Cory-Slechta D. A., Richfield E. K., Buckley B. Mirochnitchenko O. (2005) Overexpression of superoxide dismutase or glutathione peroxidase protects against the paraquat + maneb-induced Parkinson disease phenotype. J. Biol. Chem. 2005 (280 22530 22539.
-
(2005)
J. Biol. Chem.
, vol.2005
, Issue.280
, pp. 22530-22539
-
-
Thiruchelvam, M.1
Prokopenko, O.2
Cory-Slechta, D.A.3
Richfield, E.K.4
Buckley, B.5
Mirochnitchenko, O.6
-
32
-
-
0035956874
-
Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
-
Vila M., Jackson-Lewis V., Vukosavic S., Djaldetti R., Liberatore G., Offen D., Korsmeyer S. J. Przedborski S. (2001) Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine mouse model of Parkinson's disease. Proc. Natl Acad. Sci. USA 98, 2837 2842.
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 2837-2842
-
-
Vila, M.1
Jackson-Lewis, V.2
Vukosavic, S.3
Djaldetti, R.4
Liberatore, G.5
Offen, D.6
Korsmeyer, S.J.7
Przedborski, S.8
-
33
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Wei M. C., Zong W. X., Cheng E. H., Lindsten T., Panoutsakopoulou V., Ross A. J., Roth K. A., MacGregor G. R., Thompson C. B. Korsmeyer S. J. (2001) Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 292, 727 730.
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
MacGregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
-
34
-
-
22244464818
-
Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins
-
Willis S. N., Chen L., Dewson G., Wei A., Naik E., Fletcher J. I., Adams J. M. Huang D. C. (2005) Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins. Genes Dev. 19, 1294 1305.
-
(2005)
Genes Dev.
, vol.19
, pp. 1294-1305
-
-
Willis, S.N.1
Chen, L.2
Dewson, G.3
Wei, A.4
Naik, E.5
Fletcher, J.I.6
Adams, J.M.7
Huang, D.C.8
-
35
-
-
33846964621
-
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak
-
Willis S. N., Fletcher J. I., Kaufmann T. et al. (2007) Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak. Science 315, 856 859.
-
(2007)
Science
, vol.315
, pp. 856-859
-
-
Willis, S.N.1
Fletcher, J.I.2
Kaufmann, T.3
-
36
-
-
4444225471
-
Proteasomal inhibition induced by manganese ethylene-bis-dithiocarbamate: Relevance to Parkinson's disease
-
Zhou Y., Shie F. S., Piccardo P., Montine T. J. Zhang J. (2004) Proteasomal inhibition induced by manganese ethylene-bis-dithiocarbamate: relevance to Parkinson's disease. Neuroscience 128, 281 291.
-
(2004)
Neuroscience
, vol.128
, pp. 281-291
-
-
Zhou, Y.1
Shie, F.S.2
Piccardo, P.3
Montine, T.J.4
Zhang, J.5
|