Potent synergistic anti-Human Immunodeficiency Virus (HIV) effects using combinations of the CCR5 inhibitor aplaviroc with other anti-HIV drugs

Antimicrobial Agents and Chemotherapy

Volumn 52, Issue 6, 2008, Pages 2111-2119

  Nakata, Hirotomo ^a,b   Steinberg, Seth M ^a   Kon, Yasuhiro ^b   Maeda, Kenji ^a   Takaoka, Yoshikazu ^c   Tamamura, Hirokazu ^d   Fujii, Nobutaka ^d   Mitsuya, Hiroaki ^a,b,e  

^a NATIONAL CANCER INSTITUTE   (United States)

^b KUMAMOTO UNIVERSITY   (Japan)

^c ONO PHARMACEUTICAL CO   (Japan)

^d KYOTO UNIVERSITY   (Japan)

^e KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 [(4 BROMOPHENYL)(ETHOXYIMINO)METHYL] 1' [(2,4 DIMETHYL 3 PYRIDINYL)CARBONYL] 4' METHYL 1,4' BIPIPERIDINE; ANTIVIRUS AGENT; APLAVIROC; CHEMOKINE RECEPTOR CCR5 ANTAGONIST; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; ENFUVIRTIDE; INDINAVIR; MARAVIROC; N [4 [[[6,7 DIHYDRO 2 (4 METHYLPHENYL) 5H BENZOCYCLOHEPTEN 8 YL]CARBONYL]AMINO]BENZYL] N,N DIMETHYL 2H TETRAHYDROPYRAN 4 AMINIUM CHLORIDE; NEVIRAPINE; PLERIXAFOR; TE 14011; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; COMBO METHOD; CONCENTRATION RESPONSE; DRUG ANTAGONISM; DRUG EFFICACY; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENTIATION; FOOD AND DRUG ADMINISTRATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; IN VITRO STUDY; MATHEMATICAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; STATISTICAL ANALYSIS; TECHNIQUE; VIRUS INHIBITION; VIRUS REPLICATION; VIRUS STRAIN;

ANTI-HIV AGENTS; BENZOATES; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; HETEROCYCLIC COMPOUNDS; HIV FUSION INHIBITORS; HIV-1; HUMANS; LEUKOCYTES, MONONUCLEAR; PIPERAZINES; RECEPTORS, CCR5; RECEPTORS, CXCR4; SPIRO COMPOUNDS; VIRUS REPLICATION;

EID: 44449125062     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.01299-07     Document Type: Article

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