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Volumn 128, Issue 2, 2004, Pages 160-169

Glutamate mediates cell death and increases the Bax to Bcl-2 ratio in a differentiated neuronal cell line

Author keywords

Bax; Bcl 2; Excitatory amino acids: excitotoxicity; Excitotoxicity; Glutamate toxicity; N1E 115 cells; Neuron; Neurotransmitters, modulators, transporters, and receptors

Indexed keywords

GLUTAMIC ACID; PROTEIN BAX; PROTEIN BCL 2;

EID: 4444286075     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbrainres.2004.06.011     Document Type: Article
Times cited : (70)

References (72)
  • 1
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adams J.M., Cory S. The Bcl-2 protein family: arbiters of cell survival. Science. 281:1998;1322-1326
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 3
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
    • Ankarcrona M., Dypbukt J.M., Bonfoco E., Zhivotovsky B., Orrenius S., Lipton S.A., Nicotera P. Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron. 15:1995;961-973
    • (1995) Neuron , vol.15 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3    Zhivotovsky, B.4    Orrenius, S.5    Lipton, S.A.6    Nicotera, P.7
  • 4
    • 0027427493 scopus 로고
    • Bcl-2 affects survival but not neuronal differentiation of PC12 cells
    • Batistatou A., Merry D.E., Korsmeyer S.J., Greene L.A. Bcl-2 affects survival but not neuronal differentiation of PC12 cells. J. Neurosci. 13:1993;4422-4428
    • (1993) J. Neurosci. , vol.13 , pp. 4422-4428
    • Batistatou, A.1    Merry, D.E.2    Korsmeyer, S.J.3    Greene, L.A.4
  • 5
    • 0029153913 scopus 로고
    • Apoptosis and necrosis: Two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures
    • Bonfoco E., Krainc D., Ankarcrona M., Nicotera P., Lipton S.A. Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc. Natl. Acad. Sci. U. S. A. 92:1995;7162-7166
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 7162-7166
    • Bonfoco, E.1    Krainc, D.2    Ankarcrona, M.3    Nicotera, P.4    Lipton, S.A.5
  • 6
    • 0017184389 scopus 로고
    • A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein dye binding
    • Bradford M.M. A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72:1976;248-254
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 7
    • 0029884441 scopus 로고    scopus 로고
    • Expression of the apoptosis-effector gene, Bax, is up-regulated in vulnerable hippocampal CA1 neurons following global ischemia
    • Chen J., Zhu R.L., Nakayama M., Kawaguchi K., Jin K., Atetler R.A., Simon R.P., Graham S.H. Expression of the apoptosis-effector gene, Bax, is up-regulated in vulnerable hippocampal CA1 neurons following global ischemia. J. Neurochem. 67:1996;64-71
    • (1996) J. Neurochem. , vol.67 , pp. 64-71
    • Chen, J.1    Zhu, R.L.2    Nakayama, M.3    Kawaguchi, K.4    Jin, K.5    Atetler, R.A.6    Simon, R.P.7    Graham, S.H.8
  • 8
    • 0023137252 scopus 로고
    • Ionic dependence of glutamate neurotoxicity
    • Choi D.W. Ionic dependence of glutamate neurotoxicity. J. Neurosci. 7:1987;369-379
    • (1987) J. Neurosci. , vol.7 , pp. 369-379
    • Choi, D.W.1
  • 9
    • 0026497926 scopus 로고
    • Excitotoxic cell death
    • Choi D.W. Excitotoxic cell death. J. Neurobiol. 23:1992;1261-1276
    • (1992) J. Neurobiol. , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 11
    • 0029968216 scopus 로고    scopus 로고
    • Morphological differentiation of N1E-115 neuroblastoma cells by dimethyl sulfoxide activation of lipid second messengers
    • Clejan S., Dotson R.S., Wolf E.W., Corb M.P., Ide C.F. Morphological differentiation of N1E-115 neuroblastoma cells by dimethyl sulfoxide activation of lipid second messengers. Exp. Cell Res. 224:1996;16-27
    • (1996) Exp. Cell Res. , vol.224 , pp. 16-27
    • Clejan, S.1    Dotson, R.S.2    Wolf, E.W.3    Corb, M.P.4    Ide, C.F.5
  • 12
    • 0028290311 scopus 로고
    • Formation of the large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes
    • Cohen G.M., Sun X.M., Fearnhead H., MacFarlane M., Brown D.G., Snowden R.T., Dinsdale D. Formation of the large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes. J. Immunol. 153:1994;507-516
    • (1994) J. Immunol. , vol.153 , pp. 507-516
    • Cohen, G.M.1    Sun, X.M.2    Fearnhead, H.3    MacFarlane, M.4    Brown, D.G.5    Snowden, R.T.6    Dinsdale, D.7
  • 13
    • 0033565557 scopus 로고    scopus 로고
    • The mitochondrial permeability transition pore and its role in cell death
    • Crompton M. The mitochondrial permeability transition pore and its role in cell death. Biochem. J. 341(Pt. 2):1999;233-249
    • (1999) Biochem. J. , vol.341 , Issue.PART 2 , pp. 233-249
    • Crompton, M.1
  • 15
    • 0028918483 scopus 로고
    • Transcriptional or translational inhibition blocks low dose NMDA-mediated cell death
    • Dreyer E.B., Zhang D., Lipton S.A. Transcriptional or translational inhibition blocks low dose NMDA-mediated cell death. NeuroReport. 6:1995;942-944
    • (1995) NeuroReport , vol.6 , pp. 942-944
    • Dreyer, E.B.1    Zhang, D.2    Lipton, S.A.3
  • 16
    • 0034518449 scopus 로고    scopus 로고
    • Mitochondria and Ca(2+) in cell physiology and pathophysiology
    • Duchen M.R. Mitochondria and Ca(2+) in cell physiology and pathophysiology. Cell Calcium. 28(5-6):2000;339-348
    • (2000) Cell Calcium , vol.28 , Issue.56 , pp. 339-348
    • Duchen, M.R.1
  • 17
    • 0031438851 scopus 로고    scopus 로고
    • Analysis of the mechanism of loss of trophic factor dependence associated with neuronal maturation: A phenotype indistinguishable from BAX deletion
    • Easton R.M., Deckwerth T.L., Parsadanian A.S., Johnson E.M. Jr. Analysis of the mechanism of loss of trophic factor dependence associated with neuronal maturation: a phenotype indistinguishable from BAX deletion. J. Neurosci. 17:1997;9656-9666
    • (1997) J. Neurosci. , vol.17 , pp. 9656-9666
    • Easton, R.M.1    Deckwerth, T.L.2    Parsadanian, A.S.3    Johnson Jr., E.M.4
  • 18
    • 0030970350 scopus 로고    scopus 로고
    • Cellular and molecular correlates of glutamate-evoked neuronal programmed cell death in the in vitro cultures of rat hippocampal dentate gyrus
    • Figiel I., Kaczmarek L. Cellular and molecular correlates of glutamate-evoked neuronal programmed cell death in the in vitro cultures of rat hippocampal dentate gyrus. Neurochem. Int. 31:1997;229-240
    • (1997) Neurochem. Int. , vol.31 , pp. 229-240
    • Figiel, I.1    Kaczmarek, L.2
  • 19
  • 20
    • 0037187807 scopus 로고    scopus 로고
    • Angiotensin protects cortical neurons from hypoxic-induced apoptosis via the angiotensin type 2 receptor
    • Grammatopoulos T., Morris K., Ferguson P., Weyhenmeyer J. Angiotensin protects cortical neurons from hypoxic-induced apoptosis via the angiotensin type 2 receptor. Brain Res. Mol. Brain. 99(2):2002;114-124
    • (2002) Brain Res. Mol. Brain. , vol.99 , Issue.2 , pp. 114-124
    • Grammatopoulos, T.1    Morris, K.2    Ferguson, P.3    Weyhenmeyer, J.4
  • 21
    • 0346095187 scopus 로고    scopus 로고
    • Angiotensin II attenuates chemical hypoxia-induced caspase-3 activation in primary cortical neuronal cultures
    • Grammatopoulos T., Morris K., Bachar C., Moore S., Andres R.D., Weyhenmeyer J.A. Angiotensin II attenuates chemical hypoxia-induced caspase-3 activation in primary cortical neuronal cultures. Brain Res. Mol. Brain. 62(4):2004;297-303
    • (2004) Brain Res. Mol. Brain , vol.62 , Issue.4 , pp. 297-303
    • Grammatopoulos, T.1    Morris, K.2    Bachar, C.3    Moore, S.4    Andres, R.D.5    Weyhenmeyer, J.A.6
  • 23
    • 0036892748 scopus 로고    scopus 로고
    • Multiple aspects of homocysteine neurotoxicity: Glutamate excitotoxicity, kinase hyperactivation and DNA damage
    • Ho P.I., Ortiz D., Rogers E., Shea T.B. Multiple aspects of homocysteine neurotoxicity: glutamate excitotoxicity, kinase hyperactivation and DNA damage. J. Neurosci. Res. 70(5):2002;694-702
    • (2002) J. Neurosci. Res. , vol.70 , Issue.5 , pp. 694-702
    • Ho, P.I.1    Ortiz, D.2    Rogers, E.3    Shea, T.B.4
  • 24
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery D., Nunez G., Milliman C., Schreiber R.D., Korsmeyer S.J. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature. 348:1990;334-336
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenbery, D.1    Nunez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 25
    • 0030272509 scopus 로고    scopus 로고
    • Excitotoxic lesion of rat brain with quinolinic acid induces expression of p53 messenger RNA and protein and p53-inducible genes BAX and GADD-45 in brain areas showing DNA fragmentation
    • Hughes P.E., Alexi T., Yoshida T., Schreiber S.S., Knusel B. Excitotoxic lesion of rat brain with quinolinic acid induces expression of p53 messenger RNA and protein and p53-inducible genes BAX and GADD-45 in brain areas showing DNA fragmentation. Neuroscience. 74:1996;1143-1160
    • (1996) Neuroscience , vol.74 , pp. 1143-1160
    • Hughes, P.E.1    Alexi, T.2    Yoshida, T.3    Schreiber, S.S.4    Knusel, B.5
  • 26
    • 0029871310 scopus 로고    scopus 로고
    • Nuclear disintegration as a leading step of glutamate excitotoxicity in brain neurons
    • Ikeda J., Terakawa S., Murota S., Morita I., Hirakawa K. Nuclear disintegration as a leading step of glutamate excitotoxicity in brain neurons. J. Neurosci. Res. 43:1996;613-622
    • (1996) J. Neurosci. Res. , vol.43 , pp. 613-622
    • Ikeda, J.1    Terakawa, S.2    Murota, S.3    Morita, I.4    Hirakawa, K.5
  • 27
    • 0029933694 scopus 로고    scopus 로고
    • Regulation of Bcl-2 protein expression in human neuroblastoma SH-SY5Y cells: Positive and negative effects of protein kinases C and A, respectively
    • Itano Y., Ito A., Uehara T., Nomura Y. Regulation of Bcl-2 protein expression in human neuroblastoma SH-SY5Y cells: positive and negative effects of protein kinases C and A, respectively. J. Neurochem. 67:1996;131-137
    • (1996) J. Neurochem. , vol.67 , pp. 131-137
    • Itano, Y.1    Ito, A.2    Uehara, T.3    Nomura, Y.4
  • 28
    • 0033951989 scopus 로고    scopus 로고
    • Diphosphorylation and involvement of Extracellular signal-regulated kinases (ERK1/2) in glutamate-induced apoptotic-like death in cultured rat cortical neurons
    • Jiang Q., Gu Z., Zhang G., Jing G. Diphosphorylation and involvement of Extracellular signal-regulated kinases (ERK1/2) in glutamate-induced apoptotic-like death in cultured rat cortical neurons. Brain Res. 857:2000;71-77
    • (2000) Brain Res. , vol.857 , pp. 71-77
    • Jiang, Q.1    Gu, Z.2    Zhang, G.3    Jing, G.4
  • 29
    • 0034731555 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor activation results in regulation of Extracellular signal-regulated kinases by protein kinases and phosphatases in glutamate-induced neuronal apoptotic-like death
    • Jiang Q., Gu Z., Zhang G., Jing G. N-methyl-D-aspartate receptor activation results in regulation of Extracellular signal-regulated kinases by protein kinases and phosphatases in glutamate-induced neuronal apoptotic-like death. Brain Res. 887:2000;285-292
    • (2000) Brain Res. , vol.887 , pp. 285-292
    • Jiang, Q.1    Gu, Z.2    Zhang, G.3    Jing, G.4
  • 30
    • 0036498865 scopus 로고    scopus 로고
    • Genetic analysis of the mammalian cell death machinery
    • Joza N., Kroemer G., Penninger J. Genetic analysis of the mammalian cell death machinery. Trends Genet. 18:2002;142-149
    • (2002) Trends Genet. , vol.18 , pp. 142-149
    • Joza, N.1    Kroemer, G.2    Penninger, J.3
  • 31
    • 17144442776 scopus 로고    scopus 로고
    • Nerve growth factor rescues PC12 cells from apoptosis by increasing amount of bcl-2
    • Katoh S., Mitsui Y., Kitani K., Suzuki T. Nerve growth factor rescues PC12 cells from apoptosis by increasing amount of bcl-2. Biochem. Biophys. Res. Commun. 229:1996;653-657
    • (1996) Biochem. Biophys. Res. Commun. , vol.229 , pp. 653-657
    • Katoh, S.1    Mitsui, Y.2    Kitani, K.3    Suzuki, T.4
  • 32
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr J.F.R., Wyllie A.H., Currie A.R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer. 26:1972;239-257
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 33
    • 0033574565 scopus 로고    scopus 로고
    • S-nitrosation ameliorates homocysteine-induced neurotoxicity and calcium responses in primary culture of rat cortical neurons
    • Kim W.K. S-nitrosation ameliorates homocysteine-induced neurotoxicity and calcium responses in primary culture of rat cortical neurons. Neurosci. Lett. 265(2):1999;99-102
    • (1999) Neurosci. Lett. , vol.265 , Issue.2 , pp. 99-102
    • Kim, W.K.1
  • 34
    • 4444250138 scopus 로고
    • Maturation of neuroblastoma cells in the presence of dimethylsulfoxide
    • Kimhi Y., Parfrey C., Spector I., Barak Y., Littauer U.Z. Maturation of neuroblastoma cells in the presence of dimethylsulfoxide. Biochemistry. 73:1976;463-466
    • (1976) Biochemistry , vol.73 , pp. 463-466
    • Kimhi, Y.1    Parfrey, C.2    Spector, I.3    Barak, Y.4    Littauer, U.Z.5
  • 35
    • 0020051129 scopus 로고
    • Delayed neuronal death in the gerbil hippocampus following ischemia
    • Kirino T. Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res. 239(1):1982;57-69
    • (1982) Brain Res. , vol.239 , Issue.1 , pp. 57-69
    • Kirino, T.1
  • 36
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene bcl-2 and its role in regulating apoptosis
    • Kroemer G. The proto-oncogene bcl-2 and its role in regulating apoptosis. Nat. Med. 3:1997;614-620
    • (1997) Nat. Med. , vol.3 , pp. 614-620
    • Kroemer, G.1
  • 39
    • 0034666267 scopus 로고    scopus 로고
    • Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity
    • Kruman I.I., Culmsee C., Chan S.L., Kruman Y., Guo Z., Penix L., Mattson M.P. Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity. J. Neurosci. 20(18):2000;6920-6926
    • (2000) J. Neurosci. , vol.20 , Issue.18 , pp. 6920-6926
    • Kruman, I.I.1    Culmsee, C.2    Chan, S.L.3    Kruman, Y.4    Guo, Z.5    Penix, L.6    Mattson, M.P.7
  • 41
    • 0028841187 scopus 로고
    • Differentiation of neuroblastoma enhances Bcl-2 expression and induces alterations of apoptosis and drug resistance
    • Lasorella A., Iavarone A., Israel M.A. Differentiation of neuroblastoma enhances Bcl-2 expression and induces alterations of apoptosis and drug resistance. Cancer Res. 55:1995;4711-4716
    • (1995) Cancer Res. , vol.55 , pp. 4711-4716
    • Lasorella, A.1    Iavarone, A.2    Israel, M.A.3
  • 42
    • 0001739436 scopus 로고    scopus 로고
    • Stretch-mediated release of angiotensin II induces myocyte apoptosis by activation p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax ratio in the cell
    • Leri A., Claudio P.P., Li Q., Wang X., Reiss K., Wang S., Malhotra A., Kajstura J., Anversa P. Stretch-mediated release of angiotensin II induces myocyte apoptosis by activation p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax ratio in the cell. J. Clin. Invest. 101:1998;1326-1342
    • (1998) J. Clin. Invest. , vol.101 , pp. 1326-1342
    • Leri, A.1    Claudio, P.P.2    Li, Q.3    Wang, X.4    Reiss, K.5    Wang, S.6    Malhotra, A.7    Kajstura, J.8    Anversa, P.9
  • 45
    • 0344447069 scopus 로고    scopus 로고
    • Bcl-2 accelerates the maturation of early sensory neurons
    • Middleton G., Pinon L.G.P., Wyatt S., Davis A.M. Bcl-2 accelerates the maturation of early sensory neurons. J. Neurosci. 18:1998;3344-3350
    • (1998) J. Neurosci. , vol.18 , pp. 3344-3350
    • Middleton, G.1    Pinon, L.G.P.2    Wyatt, S.3    Davis, A.M.4
  • 46
    • 0030797727 scopus 로고    scopus 로고
    • Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death
    • Miller T.M., Moulder K.L., Knudson C.M., Creedon D.J., Deshmukh M., Korsmeyer S.J., Johnson E.M. Jr. Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death. J. Cell Biol. 139:1997;205-217
    • (1997) J. Cell Biol. , vol.139 , pp. 205-217
    • Miller, T.M.1    Moulder, K.L.2    Knudson, C.M.3    Creedon, D.J.4    Deshmukh, M.5    Korsmeyer, S.J.6    Johnson Jr., E.M.7
  • 47
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human Bax gene
    • Miyashita T., Reed J.C. Tumor suppressor p53 is a direct transcriptional activator of the human Bax gene. Cell. 80:1995;293-299
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 48
    • 0027261312 scopus 로고
    • N-methyl-D-aspartate receptor agonists decrease proto-oncogene Bcl-2 mRNA expression in cultured rat cerebellar granule neurons
    • Montpied P., Weller M., Paul S.M. N-methyl-D-aspartate receptor agonists decrease proto-oncogene Bcl-2 mRNA expression in cultured rat cerebellar granule neurons. Biochem. Biophys. Res. Commun. 195:1993;623-629
    • (1993) Biochem. Biophys. Res. Commun. , vol.195 , pp. 623-629
    • Montpied, P.1    Weller, M.2    Paul, S.M.3
  • 49
    • 0030636838 scopus 로고    scopus 로고
    • Stimulation and inhibition of nitric oxide production in macrophages and neural cells as observed by spin trapping
    • Norby S.W., Weyhenmeyer J.A., Clarkson R.B. Stimulation and inhibition of nitric oxide production in macrophages and neural cells as observed by spin trapping. Free Radical Biol. Med. 22:1997;1-9
    • (1997) Free Radical Biol. Med. , vol.22 , pp. 1-9
    • Norby, S.W.1    Weyhenmeyer, J.A.2    Clarkson, R.B.3
  • 50
    • 0029991311 scopus 로고    scopus 로고
    • Bcl-2 inhibits retinoic acid-induced apoptosis during the neural differentiation of embryonic stem cells
    • Okazawa H., Shimizu J., Kamei M., Imafuku I., Hamada H., Kanazawa I. Bcl-2 inhibits retinoic acid-induced apoptosis during the neural differentiation of embryonic stem cells. J. Cell Biol. 132:1996;955-968
    • (1996) J. Cell Biol. , vol.132 , pp. 955-968
    • Okazawa, H.1    Shimizu, J.2    Kamei, M.3    Imafuku, I.4    Hamada, H.5    Kanazawa, I.6
  • 51
    • 0027166048 scopus 로고
    • Bcl-2 heterodimers in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai Z.N., Milliman C.L., Korsmeyer S.J. Bcl-2 heterodimers in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell. 74:1993;609-619
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 52
    • 0013393455 scopus 로고
    • Cell death during development of the nervous system
    • Oppenheim R.W. Cell death during development of the nervous system. Annu. Rev. Neurosci. 74:1991;609-619
    • (1991) Annu. Rev. Neurosci. , vol.74 , pp. 609-619
    • Oppenheim, R.W.1
  • 53
    • 0030581738 scopus 로고    scopus 로고
    • Flupirtine increases the levels of glutathione and Bcl-2 in hNT (human Ntera/D1) neurons: Mode of action of the drug-mediated anti-apoptotic effect
    • Perovic S., Pialoglou P., Schroder H., Pergande G., Muller W. Flupirtine increases the levels of glutathione and Bcl-2 in hNT (human Ntera/D1) neurons: mode of action of the drug-mediated anti-apoptotic effect. Eur. J. Pharmacol. 317:1996;157-164
    • (1996) Eur. J. Pharmacol. , vol.317 , pp. 157-164
    • Perovic, S.1    Pialoglou, P.2    Schroder, H.3    Pergande, G.4    Muller, W.5
  • 54
  • 56
    • 0016687593 scopus 로고
    • Differentiation of neuroblastoma cells in culture
    • Prasad K.N. Differentiation of neuroblastoma cells in culture. Biol. Rev. Camb. Philos. Soc. 50:1975;129-165
    • (1975) Biol. Rev. Camb. Philos. Soc. , vol.50 , pp. 129-165
    • Prasad, K.N.1
  • 57
    • 0033561799 scopus 로고    scopus 로고
    • Nuclear factor κb nuclear translocation upregulates c-Myc and p53 expression during NMDA receptor-mediated apoptosis in rat striatum
    • Qin Z.-H., Chen R.-W., Wang Y., Nakai M., Chuang D.-M., Chase T.N. Nuclear factor κB nuclear translocation upregulates c-Myc and p53 expression during NMDA receptor-mediated apoptosis in rat striatum. J. Neurosci. 19:1999;4023-4033
    • (1999) J. Neurosci. , vol.19 , pp. 4023-4033
    • Qin, Z.-H.1    Chen, R.-W.2    Wang, Y.3    Nakai, M.4    Chuang, D.-M.5    Chase, T.N.6
  • 59
    • 0027655167 scopus 로고
    • Cycloheximide prevents kainate-induced neuronal death and c-fos expression in adult rat brain
    • Schreiber S.S., Tocco G., Najm I., Thompson R.F., Baudry M. Cycloheximide prevents kainate-induced neuronal death and c-fos expression in adult rat brain. J. Mol. Neurosci. 4:1993;149-159
    • (1993) J. Mol. Neurosci. , vol.4 , pp. 149-159
    • Schreiber, S.S.1    Tocco, G.2    Najm, I.3    Thompson, R.F.4    Baudry, M.5
  • 60
    • 0030898680 scopus 로고    scopus 로고
    • Bax deficiency prevents the increased cell death of immature neurons in Bcl-x-deficient mice
    • Shindler K.S., Latham C.B., Roth K.A. Bax deficiency prevents the increased cell death of immature neurons in Bcl-x-deficient mice. J. Neurosci. 17:1997;3112-3119
    • (1997) J. Neurosci. , vol.17 , pp. 3112-3119
    • Shindler, K.S.1    Latham, C.B.2    Roth, K.A.3
  • 61
    • 4444343604 scopus 로고
    • Cloning of the chromosome breakpoint of neoplastic B cells with the t (14:18) chromosome translocation
    • Tsujimoto Y., Finger L., Tunis J., Nowell P., Croce C. Cloning of the chromosome breakpoint of neoplastic B cells with the t (14:18) chromosome translocation. Science. 90:1984;4533-4537
    • (1984) Science , vol.90 , pp. 4533-4537
    • Tsujimoto, Y.1    Finger, L.2    Tunis, J.3    Nowell, P.4    Croce, C.5
  • 62
    • 0031001244 scopus 로고    scopus 로고
    • Bax promotes neuronal cell death and is downregulated during the development of the nervous system
    • Vekrellis K., McCarthy M.J., Watson A., Whitfield J., Rubin L.L., Ham J. Bax promotes neuronal cell death and is downregulated during the development of the nervous system. Development. 124:1997;1239-1249
    • (1997) Development , vol.124 , pp. 1239-1249
    • Vekrellis, K.1    McCarthy, M.J.2    Watson, A.3    Whitfield, J.4    Rubin, L.L.5    Ham, J.6
  • 63
    • 0030776519 scopus 로고    scopus 로고
    • Comparison of the neuroprotective effects of APV and bcl-2 in glutamate-induced cell death
    • Wang Y., Jia W., Cynader M. Comparison of the neuroprotective effects of APV and bcl-2 in glutamate-induced cell death. NeuroReport. 8:1997;3323-3326
    • (1997) NeuroReport , vol.8 , pp. 3323-3326
    • Wang, Y.1    Jia, W.2    Cynader, M.3
  • 64
    • 0031912196 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor desensitization is neuroprotective by inhibiting glutamate-induced apoptotic-like death
    • Wood A.M., Bristow D.R. N-methyl-D-aspartate receptor desensitization is neuroprotective by inhibiting glutamate-induced apoptotic-like death. J. Neurochem. 70:1998;677-687
    • (1998) J. Neurochem. , vol.70 , pp. 677-687
    • Wood, A.M.1    Bristow, D.R.2
  • 65
    • 0028206341 scopus 로고
    • BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax
    • Yin X.M., Oltvai Z.N., Korsmeyer S.J. BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. Nature. 369:1994;321-323
    • (1994) Nature , vol.369 , pp. 321-323
    • Yin, X.M.1    Oltvai, Z.N.2    Korsmeyer, S.J.3
  • 67
    • 0027304383 scopus 로고
    • Bcl-2 blocks glutamate toxicity in neural cell lines
    • Zhong L., Kane D., Bredesen D. Bcl-2 blocks glutamate toxicity in neural cell lines. Mol. Brain Res. 19:1993;353-355
    • (1993) Mol. Brain Res. , vol.19 , pp. 353-355
    • Zhong, L.1    Kane, D.2    Bredesen, D.3
  • 69
    • 0038664379 scopus 로고    scopus 로고
    • Role of group I metabotropic glutamate receptors and NMDA receptors in homocysteine-evoked acute neurodegeneration of cultured cerebellar granule neurones
    • Zieminska E., Stafiej A., Lazarewicz J.W. Role of group I metabotropic glutamate receptors and NMDA receptors in homocysteine-evoked acute neurodegeneration of cultured cerebellar granule neurones. Neurochem. Int. 43(4-5):2003;481-492
    • (2003) Neurochem. Int. , vol.43 , Issue.45 , pp. 481-492
    • Zieminska, E.1    Stafiej, A.2    Lazarewicz, J.W.3
  • 70
    • 0030745646 scopus 로고    scopus 로고
    • Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
    • Zou H., Henzel W.J., Liu X., Lutschg A., Wang X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell. 90:1997;405-413
    • (1997) Cell , vol.90 , pp. 405-413
    • Zou, H.1    Henzel, W.J.2    Liu, X.3    Lutschg, A.4    Wang, X.5
  • 71
    • 0032569987 scopus 로고    scopus 로고
    • Expression of the p75 TNF receptor and protein its role in contact-mediated neuronal cell death
    • Sipe K., Dantzer R., Kelley K., Weyhenmeyer J.A. Expression of the p75 TNF receptor and protein its role in contact-mediated neuronal cell death. Mol. Brain Res. 62:1998;111-121
    • (1998) Mol. Brain Res. , vol.62 , pp. 111-121
    • Sipe, K.1    Dantzer, R.2    Kelley, K.3    Weyhenmeyer, J.A.4
  • 72
    • 4344614296 scopus 로고    scopus 로고
    • Angiotensin II attenuates NMDA receptor-mediated neuronal cell death and prevents the associated reduction in Bcl-2 expression
    • (in press).
    • W.R. Schelman, R. Andres, P. Ferguson, B. Orr, E. Kang, J.A. Weyhenmeyer, Angiotensin II attenuates NMDA receptor-mediated neuronal cell death and prevents the associated reduction in Bcl-2 expression, Mol. Brain Res. (in press).
    • Mol. Brain Res.
    • Schelman, W.R.1    Andres, R.2    Ferguson, P.3    Orr, B.4    Kang, E.5    Weyhenmeyer, J.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.