Actin overexpression parallels severity of pancreatic injury

Experimental Cell Research

Volumn 299, Issue 2, 2004, Pages 404-414

  Zhong, Bihui ^a,b,c   Omary, M Bishr ^a,b,d  

^a VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^b Stanford California and Cofounder   (United States)

^c SUN YAT SEN UNIVERSITY   (China)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Ab; act D; actinomycin D; antibody; Caerulein; CDD; choline deficient diet; Choline deficient diet; FITC; fluorescein isothiocyanate; heat stress protein; Hsp; IF; intermediate filament(s); Intermediate filaments; intraperitoneal; ip; K; keratin; Pancreatitis; Tubulin

Indexed keywords

ACTIN; DACTINOMYCIN; KERATIN; RNA; TUBULIN;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISEASE SEVERITY; EX VIVO STUDY; GENE OVEREXPRESSION; MOUSE; NONHUMAN; PANCREAS INJURY; PANCREATITIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; UPREGULATION;

TRIXIS;

EID: 4444224935     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2004.05.026     Document Type: Article

References (51)

1. Ku N.O., Zhou X., Toivola D.M., Omary M.B. The cytoskeleton of digestive epithelia in health and disease. Am. J. Physiol. 277:1999;G1108-G1137
2. Moll R., Franke W.W., Schiller D.L., Geiger B., Krepler R. The catalog of human cytokeratins: patterns of expression in normal epithelia, tumor and cultured cells. Cell. 31:1982;11-24
3. Coulombe P.A., Omary M.B. "Hard" and "soft" principles defining the structure, function and regulation of keratin intermediate filaments. Curr. Opin. Cell Biol. 14:2002;110-122
4. Zhou Q., Toivola D.M., Feng N.G., Greenberg H.B., Franke W.W., Omary M.B. Keratin 20 helps maintain intermediate filament organization in intestinal epithelia. Mol. Biol. Cell. 14:2003;2959-2971
5. Pollard T.D. The cytoskeleton, cellular motility and the reductionist agenda. Nature. 422:2003;741-745
6. Martin E.R., Scott W.K., Nance M.A., Watts R.L., Hubble J.P., Koller W.C., Lyons K., Pahwa R., Stern M.B., Colcher A., Hiner B.C., Jankovic J., Ondo W.G., Allen F.H.J., Goetz C.G., Small G.W., Masterman D., Mastaglia F., Laing N.G., Stajich J.M., Ribble R.C., Booze M.W., Rogala A., Hauser M.A., Zhang F., Gibson R.A., Middleton L.T., Roses A.D., Haines J.L., Scott B.L., Pericak-Vance M.A., Vance J.M. Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease. JAMA. 286:2001;2245-2250
7. Seidman J.G., Seidman C. The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms. Cell. 104:2001;557-567
8. Omary M.B., Ku N.O., Toivola D.M. Keratins: guardians of the liver. Hepatology. 35:2002;251-257
9. Irvine A.D., Mclean W.H. Human keratin diseases: the increasing spectrum of disease and subtlety of the phenotype-genotype correlation. Br. J. Dermatol. 140:1999;815-828
10. Al-chalabi A., Miller C.C.J. Neurofilaments and neurological disease. BioEssays. 25:2003;346-355
11. Messing A., Brenner M. GFAP: functional implications gleaned from studies of genetically engineered mice. Glia. 43:2003;87-90
12. Mounkes L., Kozlov S., Burke B., Stewart C.L. The laminopathies: nuclear structure meets disease. Curr. Opin. Genet. Dev. 13:2003;223-230
13. Herrmann H., Hesse M., Reichenzeller M., Aebi U., Magin T.M. Functional complexity of intermediate filament cytoskeletons: from structure to assembly to gene ablation. Int. Rev. Cyt. 223:2003;83-175
14. Ku N.O., Darling J.M., Krams S.M., Esquivel C.O., Keeffe E.B., Sibley R.K., Lee Y.M., Wright T.L., Omary M.B. Keratin 8 and 18 mutations are risk factors for developing liver disease of multiple etiologies. Proc. Natl. Acad. Sci. U.S.A. 100:2003;6063-6068
15. O'Konski M.S., Pandol S.J. Effects of caerulein on the apical cytoskeleton of the pancreatic acinar cell. J. Clin. Invest. 86:1990;1649-1657
16. Jungermann J., Lerch M.M., Weidenbach H., Lutz M.P., Kruger B., Adler G. Disassembly of rat pancreatic acinar cell cytoskeleton during supramaximal secretagogue stimulation. Am. J. Physiol. 268:1995;G328-G338
17. Fallon M.B., Gorelick F.S., Anderson J.M., Mennone A., Saluja A., Steer M. Effect of cerulein hyperstimulation on the paracellular barrier of rat exocrine pancreas. Gastroenterology. 108:1995;1863-1872
18. Toivola D.M., Barbault H., Magin T., Michie S.A., Omary M.B. Simple epithelial keratins are dispensable for cytoprotection in two pancreatitis models. Am. J. Physiol. 279:2000;1343-1354
19. Toivola D.M., Ku N.O., Ghori N., Lowe A.W., Michie S.A., Omary M.B. Effects of keratin filament disruption on exocrine pancreas-stimulated secretion and susceptibility to injury. Exp. Cell Res. 255:2000;156-170
20. Cadrin M., Hovington H., Marceau N., McFarlane-Anderson N. Early perturbations in keratin and actin gene expression and fibrillar organisation in griseofulvin-fed mouse liver. J. Hepatol. 33:2000;199-207
21. Denk H., Stumptner C., Zatloukal K. Mallory bodies revisited. J. Hepatol. 32:2000;689-702
22. Fickert P., Trauner M., Fuchsbichler A., Stumptner C., Zatloukal K., Denk H. Cytokeratin as targets for bile acid-induced toxicity. Am. J. Physiol. 160:2002;491-499
23. Zhong B., Zhou Q., Toivola D.M., Tao G.Z., Resureccion E.Z., Omary M.B. Organ-specific stress induces mouse pancreatic keratin over-expression in association with NF-κB activation. J. Cell Sci. 117:2004;1709-1718
24. Tao G.Z., Toivola D.M., Zhong B., Michie S.A., Resureccion E.Z., Tamai Y., Taketo M.M., Omary M.B. Keratin-8 null mice have different gallbladder and liver susceptibility to lithogenic diet-induced injury. J. Cell Sci. 116:2003;4629-4638
25. Coulombe P.A. Wound epithelialization: accelerating the pace of discovery. J. Invest. Dermatol. 121:2003;219-230
26. Baribault H., Penner J., Iozzo R.V., Wilson-Heiner M. Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice. Genes Dev. 8:1994;2964-2973
27. Boller K., Kemler R., Baribault H., Doetschman T. Differential distribution of cytokeratins after microinjection of anti-cytokeratin monoclonal antibodies. Eur. J. Cell Biol. 43:1987;459-468
28. Ku N.O., Michie S., Oshima R.G., Omary M.B. Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved argining mutant. J. Cell Biol. 131:1995;1303-1314
29. Ku N.O., Liao J., Omary M.B. Phosphorylation of human keratin 18 serine 33 regulates binding to 14-3-3 protein. EMBO J. 17:1998;1892-1906
30. Jensen R.T., Lemp G.F., Gardner J.D. Interaction of cholecystokinin with specific membrane receptors on pancreatic acinar cells. Proc. Natl. Acad. Sci. U.S.A. 77:1980;2079-2083
31. Lombardi B., Estes L.W., Longnecker D.S. Acute hemorrhagic pancreatitis massive necrosis with fat necrosis induced in mice by DL-ethionine fed with a choline-deficient diet. Am. J. Physiol. 79:1975;465-480
32. Menozzi D., Jensen R.T., Gardner J.D. Dispersed pancreatic acinar cells and pancreatic acini. Methods Enzymol. 192:1990;271-279
33. Ku N.O., Omary M.B. Keratins turn over by ubiquitination in a phosphorylation-modulated fashion. J. Cell Biol. 149:2000;547-552
34. Kiehne K., Herzig K.H., Folsch U.R. Regulation of the actin cytoskeleton by p125 focal adhesion kinase in rat pancreatic acinar cells. Digestion. 60:1999;153-160
35. Beil M., Leser J., Lutz M.P., Gukovskaya A., Seufferlein T., Lynch G., Pandol S.J., Adler G. Caspase 8-mediated cleavage of plectin precedes F-actin breakdown in acinar cells during pancreatitis. Am. J. Physiol.: Gasterointest. Liver Physiol. 282:2002;G450-G460
36. Ueda T., Takeyama Y., Kaneda K., Adachi M., Ohyanagi H., Saitoh Y. Protective effect of a microtubule stabilizer taxol on caerulein-induced acute pancreatitis in rat. J. Clin. Invest. 89:1992;234-243
37. Yuan S., Rosenberg L., Iliva A., Agapitos D., Duguid W.P. Early changes of gene expression during cerulein supramaximal stimulation. Pancreas. 19:1999;45-50
38. Iovanna J.L., Keim V., Michel R., Dagorn J.C. Pancreatic gene expression is altered during acute experimental pancreatitis in the rat. Am. J. Physiol. 261:1991;G485-G489
39. Toivola D.M., Nieminen M.I., Hesse M., He T., Baribault H., Magin T.M., Omary M.B., Eriksson J.E. Disturbances in hepatic cell-cycle regulation in mice with assembly-deficient keratin 8/18. Hepatology. 34:2001;1174-1183
40. Cavestro G.M., Frulloni L., Nouvenne A., Neri T.M., Calore B., Ferri B., Bovo P., Okolicsanyi L., Mario F.D., Cavallini G. Association of keratin 8 gene mutation with chronic pancreatitis. Dig. Liver Dis. 35:2003;416-420
41. Casanova M.L., Bravo A., Ramirez A., Escobar G.M., Were F., Merlino G., Vidal M., Jorcano J.L. Exocrine pancreatic disorders in transgenic mice expressing human keratin 8. J. Clin. Invest. 103:1999;1587-1595
42. Ku N.O., Soetikno R.M., Omary M.B. Keratin mutation in transgenic mice predisposes to Fas but not TNF-induced apoptosis and massive liver injury. Hepatology. 37:2003;1006-10014
43. Caulin C., Ware C.F., Magin T.M., Oshima R.G. Keratin-dependent, epithelial resistance to tumor necrosis factor-induced apoptosis. J. Cell Biol. 149:2000;17-22
44. Gilbert S., Loranger A., Daigle N., Marceau N. Simple epithelium keratin 8 and 18 provide resistance to Fas-mediated apoptosis. The protection occurs through a receptor-targeting modulation. J. Cell Biol. 154:2001;763-773
45. Fu K., Sarras M.P.J., De Lisle R.C., Andrews G.K. Expression of oxidative stress-responsive genes and cytokine genes during caerulein-induced acute pancreatitis. Am. J. Physiol. 273:1997;G696-G705
46. Schulz H.U., Niederau C., Klonowski-Stumpe H., Halangk W., Luthen R., Lippert H. Oxidative stress in acute pancreatitis. Hepatogastroenterology. 46:1999;2736-2750
47. Demols A., Van Laethem J.L., Quertinmont E., Legros F., Louis H., Le Moine O., Deviere J. N-acetylcysteine decreases severity of acute pancreatitis in mice. Pancreas. 20:2000;161-169
48. Sevillano S., De La Mano A.M., De Dios I., Ramudo L., Manso M. Major pathological mechanisms of acute pancreatitis are prevented by N-acetylcysteine. Digestion. 68:2003;34-40
49. Uomo G., Talamini G., Rabitti P.G. Antioxidant treatment in hereditary pancreatitis. A pilot study on three young patients. Dig. Liver Dis. 33:2001;58-62
50. Wang J., Boja E.S., Tan W., Tekle E., Fales H.M., English S., Mieyal J.J., Chock P.B. Reversible glutathionylation regulates actin polymerization in A431 cells. J. Biol. Chem. 276:2001;47763-47766
51. Pastore A., Tozzi G., Gaeta L.M., Bertini E., Serafini V., Di Cesare S., Bonetto V., Casoni F., Carrozzo R., Federici G., Piemonte F. Actin glutathionylation increases in fibroblasts of patients with Friedreich's ataxia: a potential role in the pathogenesis of the disease. J. Biol. Chem. 278:2003;42588-42595