메뉴 건너뛰기




Volumn 149, Issue 3, 2000, Pages 547-552

Keratins turn over by ubiquitination in a phosphorylation-modulated fashion

Author keywords

Intermediate filaments; Keratins; Mallory bodies; Phosphorylation; Ubiquitination

Indexed keywords

COMPLEMENTARY DNA; KERATIN; KERATIN 18; KERATIN 8; UBIQUITIN; UNCLASSIFIED DRUG;

EID: 0034194388     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.149.3.547     Document Type: Article
Times cited : (147)

References (34)
  • 1
    • 0028876908 scopus 로고
    • Ubiquitinated cytokeratin inclusions in lichen amyloidosus: An immunohistochemical analysis
    • Akamatsu, M., S. Hori, Y. Tsutsumi, R.Y. Osamura, and M. Ohkido. 1995. Ubiquitinated cytokeratin inclusions in lichen amyloidosus: an immunohistochemical analysis. Pathol. Int. 45:116-122.
    • (1995) Pathol. Int. , vol.45 , pp. 116-122
    • Akamatsu, M.1    Hori, S.2    Tsutsumi, Y.3    Osamura, R.Y.4    Ohkido, M.5
  • 2
    • 0028941023 scopus 로고
    • Modifications in cytokeratin and actin in cultured liver cells derived from griscofulvin-fed mice
    • Cadrin, M., N.M. Anderson, L.H. Aasheim, H. Kawahara, D.J. Franks, and S.W. French. 1995. Modifications in cytokeratin and actin in cultured liver cells derived from griscofulvin-fed mice. Lab. Invest. 72:453-160.
    • (1995) Lab. Invest. , vol.72 , pp. 453-1160
    • Cadrin, M.1    Anderson, N.M.2    Aasheim, L.H.3    Kawahara, H.4    Franks, D.J.5    French, S.W.6
  • 3
    • 0030770449 scopus 로고    scopus 로고
    • Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis
    • Caulin, C., G.S. Salvesen, and R.G. Oshima. 1997. Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis. J. Cell. Biol. 138:1379-1394.
    • (1997) J. Cell. Biol. , vol.138 , pp. 1379-1394
    • Caulin, C.1    Salvesen, G.S.2    Oshima, R.G.3
  • 4
    • 0033598754 scopus 로고    scopus 로고
    • Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage
    • Chehab, N.H., A. Malikzay, E.S. Stavridi, and T.D. Halazonetis. 1999. Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage. Proc. Natl. Acad. Sci. USA. 961:13777-13782.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.961 , pp. 13777-13782
    • Chehab, N.H.1    Malikzay, A.2    Stavridi, E.S.3    Halazonetis, T.D.4
  • 5
    • 0026612429 scopus 로고
    • A leucine→proline mutation in the H1 subdomain of keratin 1 causes epidermolytic hyperkeratosis
    • Chipev, C.C., B.P. Korge, N. Markova, S.J. Bale, J.J. DiGiovanna, J.G. Compton, and P.M. Steinen. 1992. A leucine→proline mutation in the H1 subdomain of keratin 1 causes epidermolytic hyperkeratosis. Cell. 70:821-828.
    • (1992) Cell , vol.70 , pp. 821-828
    • Chipev, C.C.1    Korge, B.P.2    Markova, N.3    Bale, S.J.4    Digiovanna, J.J.5    Compton, J.G.6    Steinen, P.M.7
  • 6
    • 0026662974 scopus 로고
    • Characterization and dynamics of O-linked glycosylalion of human cylokeratin 8 and 18
    • Chou, C.-F., A.J. Smith, and M.B. Omary. 1992. Characterization and dynamics of O-linked glycosylalion of human cylokeratin 8 and 18, J. Biol. Chem. 267: 3901-3906.
    • (1992) J. Biol. Chem. , vol.267 , pp. 3901-3906
    • Chou, C.-F.1    Smith, A.J.2    Omary, M.B.3
  • 7
    • 0027244147 scopus 로고
    • A significant soluble keratin fraction in "simple" epithelial cells: Lack of an apparent phosphorylation and glycosylation role in keratin solubility
    • Chou, C.-F., C.L. Riopel, L.S. Rott, and M.B. Omary. 1993. A significant soluble keratin fraction in "simple" epithelial cells: Lack of an apparent phosphorylation and glycosylation role in keratin solubility. J. Cell Sci. 105:433-445.
    • (1993) J. Cell Sci. , vol.105 , pp. 433-445
    • Chou, C.-F.1    Riopel, C.L.2    Rott, L.S.3    Omary, M.B.4
  • 8
    • 0023502547 scopus 로고
    • Turnover of cytokeratin polypeptides in mouse hepatocytes
    • Denk, H., E. Lackinger, K. Zatloukal, and W.W. Franke. 1987. Turnover of cytokeratin polypeptides in mouse hepatocytes. Exp. Cell Res. 173:137-143.
    • (1987) Exp. Cell Res. , vol.173 , pp. 137-143
    • Denk, H.1    Lackinger, E.2    Zatloukal, K.3    Franke, W.W.4
  • 9
    • 0028283501 scopus 로고
    • Intermediate filaments: Structure, dynamics, function and disease
    • Fuchs, F., and K. Weber. 1994. Intermediate filaments: structure, dynamics, function and disease. Annu. Rev. Biochem. 63:345-382.
    • (1994) Annu. Rev. Biochem. , vol.63 , pp. 345-382
    • Fuchs, F.1    Weber, K.2
  • 10
    • 0032559341 scopus 로고    scopus 로고
    • A structural scaffolding of intermediate filaments in health and disease
    • Fuchs, E., and D.W. Cleveland. 1998. A structural scaffolding of intermediate filaments in health and disease. Science. 279:514-519.
    • (1998) Science , vol.279 , pp. 514-519
    • Fuchs, E.1    Cleveland, D.W.2
  • 12
    • 0027143143 scopus 로고
    • Disturbance of keratin humeostasis in griseofulvin-intoxicated mouse liver
    • Hutter, H., K. Zatloukal, G. Winter, C. Stumptner, and H. Denk. 1993. Disturbance of keratin humeostasis in griseofulvin-intoxicated mouse liver. Lab. Invest. 69:576-582.
    • (1993) Lab. Invest. , vol.69 , pp. 576-582
    • Hutter, H.1    Zatloukal, K.2    Winter, G.3    Stumptner, C.4    Denk, H.5
  • 13
    • 0028111112 scopus 로고
    • The Mallory body: Morphological, clinical and experimental studies
    • Jensen, K., and C. Gluud. 1994. The Mallory body: morphological, clinical and experimental studies. Hepatology. 20:1061-1077.
    • (1994) Hepatology , vol.20 , pp. 1061-1077
    • Jensen, K.1    Gluud, C.2
  • 14
    • 0032576605 scopus 로고    scopus 로고
    • Aggresomes: A cellular response to misfolded proteins
    • Johnston, J.A., C.L. Ward, and R.R. Kopito. 1998. Aggresomes: a cellular response to misfolded proteins. J Cell Biol. 143:1883-1898.
    • (1998) J Cell Biol. , vol.143 , pp. 1883-1898
    • Johnston, J.A.1    Ward, C.L.2    Kopito, R.R.3
  • 15
    • 0028106972 scopus 로고
    • Identification of the major physiologic phosphorylation site of human keratin 18: Potential kinases and a role in filament reorganization
    • Ku, N.-O., and M.B. Omary. 1994. Identification of the major physiologic phosphorylation site of human keratin 18: potential kinases and a role in filament reorganization. J. Cell Biol. 127:161-171.
    • (1994) J. Cell Biol. , vol.127 , pp. 161-171
    • Ku, N.-O.1    Omary, M.B.2
  • 16
    • 0030989811 scopus 로고    scopus 로고
    • Phosphorylation of human keratin 8 in vivo at conserved head domain serine 23 and at epidermal growth factor-stimulated tail domain serine 431
    • Ku, N.-O., and M.B. Omary. 1997. Phosphorylation of human keratin 8 in vivo at conserved head domain serine 23 and at epidermal growth factor-stimulated tail domain serine 431. J. Biol. Chem. 272:7556-7564.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7556-7564
    • Ku, N.-O.1    Omary, M.B.2
  • 17
    • 0031455379 scopus 로고    scopus 로고
    • Apoptosis generates stable fragments of human type 1 keratins
    • Ku, N.-O., J. Liao, and M.B. Omary. 1997. Apoptosis generates stable fragments of human type 1 keratins. J. Biol. Chem. 272:33197-33203.
    • (1997) J. Biol. Chem. , vol.272 , pp. 33197-33203
    • Ku, N.-O.1    Liao, J.2    Omary, M.B.3
  • 18
    • 0032055050 scopus 로고    scopus 로고
    • Phosphorylation of human keratin 18 serine 33 regulates binding to 14-3-3 proteins
    • Ku, N.-O., J. Liao, and M.B. Omary. 1998a. Phosphorylation of human keratin 18 serine 33 regulates binding to 14-3-3 proteins. EMBO (Eur. Mol. Biol. Organ.) J. 17:1892-1906.
    • (1998) EMBO (Eur. Mol. Biol. Organ.) J. , vol.17 , pp. 1892-1906
    • Ku, N.-O.1    Liao, J.2    Omary, M.B.3
  • 19
    • 0032576580 scopus 로고    scopus 로고
    • Mutation of a major keratin phosphorylation site predisposes to hepatotoxic injury in transgenic mice
    • Ku, N.-O., S.A. Michie, R.M. Soetikno, E.Z. Resurreccion, R.L. Broome, and M.B Omary. 1998b. Mutation of a major keratin phosphorylation site predisposes to hepatotoxic injury in transgenic mice. J. Cell Biol. 143:2023-2032.
    • (1998) J. Cell Biol. , vol.143 , pp. 2023-2032
    • Ku, N.-O.1    Michie, S.A.2    Soetikno, R.M.3    Resurreccion, E.Z.4    Broome, R.L.5    Omary, M.B.6
  • 20
    • 0033401358 scopus 로고    scopus 로고
    • The cytoskeleton of digestive epithelia in health and disease
    • Ku, N.-O., X. Zhou, D.M. Toivola, and M.B. Omary. 1999. The cytoskeleton of digestive epithelia in health and disease. Am. J. Physiol. 277:G1108-G1137.
    • (1999) Am. J. Physiol. , vol.277
    • Ku, N.-O.1    Zhou, X.2    Toivola, D.M.3    Omary, M.B.4
  • 21
    • 0033553532 scopus 로고    scopus 로고
    • Substrate targeting in the ubiquitin system
    • Laney, J.D., and M. Hochstrasser. 1999. Substrate targeting in the ubiquitin system. Cell. 97:427-430.
    • (1999) Cell , vol.97 , pp. 427-430
    • Laney, J.D.1    Hochstrasser, M.2
  • 22
    • 0028853614 scopus 로고
    • Dynamics of human keratin 18 phosphorylation: Polarized distribution of phosphorylated keratins in simple epithelial tissues
    • Liao, J., L.A. Lowthert, N.-O. Ku, R. Fernandez, and M.B. Omary. 1995. Dynamics of human keratin 18 phosphorylation: Polarized distribution of phosphorylated keratins in simple epithelial tissues. J. Cell Biol. 131:1241-1301.
    • (1995) J. Cell Biol. , vol.131 , pp. 1241-1301
    • Liao, J.1    Lowthert, L.A.2    Ku, N.-O.3    Fernandez, R.4    Omary, M.B.5
  • 23
    • 0030857803 scopus 로고    scopus 로고
    • Stress, apoptosis, and mitosis induce phosphorylation of human keratin 8 at ser73 in tissues and cultured cells
    • Liao, J., N.-O. Ku, and M.B. Omary. 1997. Stress, apoptosis, and mitosis induce phosphorylation of human keratin 8 at ser73 in tissues and cultured cells. J. Biol. Chem. 272:17565-17573.
    • (1997) J. Biol. Chem. , vol.272 , pp. 17565-17573
    • Liao, J.1    Ku, N.-O.2    Omary, M.B.3
  • 24
    • 0023927981 scopus 로고
    • Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodies in muscle, and Mallory bodies in alcoholic liver disease
    • Lowe, J., A. Blanchard, K. Morrell, G. Lennox, L. Reynolds, M. Billett, M. Landon, and R.J. Mayer. 1988. Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodies in muscle, and Mallory bodies in alcoholic liver disease. J. Pathol. 155:9-15.
    • (1988) J. Pathol. , vol.155 , pp. 9-15
    • Lowe, J.1    Blanchard, A.2    Morrell, K.3    Lennox, G.4    Reynolds, L.5    Billett, M.6    Landon, M.7    Mayer, R.J.8
  • 25
    • 0020467073 scopus 로고
    • The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells
    • Moll, R., W.W. Franke, D.I., Schiller, B. Geiger, and R. Krepler. 1982. The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell. 31:11-24.
    • (1982) Cell , vol.31 , pp. 11-24
    • Moll, R.1    Franke, W.W.2    Schiller, D.I.3    Geiger, B.4    Krepler, R.5
  • 26
    • 0030055476 scopus 로고    scopus 로고
    • Changes in the enterocyte cytoskeleton in newborn rats exposed to ethanol in utero
    • Montes, J.F., G. Estrada, M.D. Lopez-Tejero, and J. Garcia-Valero. 1996. Changes in the enterocyte cytoskeleton in newborn rats exposed to ethanol in utero. Gut. 38:846-852.
    • (1996) Gut , vol.38 , pp. 846-852
    • Montes, J.F.1    Estrada, G.2    Lopez-Tejero, M.D.3    Garcia-Valero, J.4
  • 27
    • 0031767288 scopus 로고    scopus 로고
    • Novel K5 and K14 mutations in German patients with the Weber-Cockayne variant of epidermolysis bullosa simplex. J. Invest
    • Muller, F.B., W. Kuster, L. Bruckner-Tuderman, and B.P. Korge. 1998. Novel K5 and K14 mutations in German patients with the Weber-Cockayne variant of epidermolysis bullosa simplex. J. Invest. Dermatol. 111:900-902.
    • (1998) Dermatol. , vol.111 , pp. 900-902
    • Muller, F.B.1    Kuster, W.2    Bruckner-Tuderman, L.3    Korge, B.P.4
  • 28
    • 0031023756 scopus 로고    scopus 로고
    • Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases
    • Musti, A.M., M. Treier, and D. Bohmann. 1997. Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases. Science. 275: 400-402.
    • (1997) Science , vol.275 , pp. 400-402
    • Musti, A.M.1    Treier, M.2    Bohmann, D.3
  • 31
    • 0028787249 scopus 로고
    • The Mos/MAP kinase pathway stabilizes c-Fos by phosphorylation and augments its transforming activity in NIH 3T3 cells
    • Okazaki, K., and N. Sagata. 1995. The Mos/MAP kinase pathway stabilizes c-Fos by phosphorylation and augments its transforming activity in NIH 3T3 cells. EMBO (Eur. Mol. Biol. Organ.) J. 14:5048-5059.
    • (1995) EMBO (Eur. Mol. Biol. Organ.) J. , vol.14 , pp. 5048-5059
    • Okazaki, K.1    Sagata, N.2
  • 32
    • 0032233993 scopus 로고    scopus 로고
    • Keratin modifications and soluble properties in epithelial cells and in vitro
    • Omary, M.B., N.-O. Ku, J. Liao, and D. Price. 1998. Keratin modifications and soluble properties in epithelial cells and in vitro. Subcell. Biochem. 31:105-139.
    • (1998) Subcell. Biochem. , vol.31 , pp. 105-139
    • Omary, M.B.1    Ku, N.-O.2    Liao, J.3    Price, D.4
  • 33
    • 0033883793 scopus 로고    scopus 로고
    • Hepatocyte cytokeratins are hyperphosphorylated at multiple sites in human alcoholic hepatitis and in a Mallory body mouse model
    • Stumptner, C., M.B. Omary, H. Denk, and K. Zatloukal. 2000. Hepatocyte cytokeratins are hyperphosphorylated at multiple sites in human alcoholic hepatitis and in a Mallory body mouse model. Am. J. Pathol. 156:77-90.
    • (2000) Am. J. Pathol. , vol.156 , pp. 77-90
    • Stumptner, C.1    Omary, M.B.2    Denk, H.3    Zatloukal, K.4
  • 34
    • 0028196637 scopus 로고
    • Adenovirus inhibition of cell translation facilitates release of virus particles and enhances degradation of the cytokeratin network
    • Zhang, Y., and R.J. Schneider. 1994. Adenovirus inhibition of cell translation facilitates release of virus particles and enhances degradation of the cytokeratin network. J. Viro. 68:2544-2555.
    • (1994) J. Viro. , vol.68 , pp. 2544-2555
    • Zhang, Y.1    Schneider, R.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.