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Volumn 37, Issue 5, 2003, Pages 1006-1014

Keratin mutation in transgenic mice predisposes to Fas but not TNF-induced apoptosis and massive liver injury

Author keywords

[No Author keywords available]

Indexed keywords

AMINOTRANSFERASE; CASPASE; DACTINOMYCIN; FAS ANTIBODY; K 18; KERATIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 0037847551     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2003.50181     Document Type: Article
Times cited : (90)

References (35)
  • 1
    • 0033401358 scopus 로고    scopus 로고
    • The cytoskeleton of digestive epithelia in health and disease
    • Ku NO, Zhou X, Toivola DM, Omary MB. The cytoskeleton of digestive epithelia in health and disease. Am J Physiol 1999;277:G1108-G1137.
    • (1999) Am J Physiol , vol.277
    • Ku, N.O.1    Zhou, X.2    Toivola, D.M.3    Omary, M.B.4
  • 2
    • 0020467073 scopus 로고
    • The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells
    • Moll R, Franke WW, Schiller DL, Geiger B, Krepler R. The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 1982;31:11-24.
    • (1982) Cell , vol.31 , pp. 11-24
    • Moll, R.1    Franke, W.W.2    Schiller, D.L.3    Geiger, B.4    Krepler, R.5
  • 3
    • 0036468732 scopus 로고    scopus 로고
    • "Hard" and "soft" principles defining the structure, function and regulation of keratin intermediate filaments
    • Coulombe PA, Omary MB. "Hard" and "soft" principles defining the structure, function and regulation of keratin intermediate filaments. Curr Opin Cell Biol 2002;14:110-122.
    • (2002) Curr Opin Cell Biol , vol.14 , pp. 110-122
    • Coulombe, P.A.1    Omary, M.B.2
  • 5
    • 0030955612 scopus 로고    scopus 로고
    • Intermediate filament proteins of the liver: Emerging disease association and functions
    • Omary MB, Ku NO. Intermediate filament proteins of the liver: emerging disease association and functions. HEPATOLOGY 1997;25:1043-1048.
    • (1997) Hepatology , vol.25 , pp. 1043-1048
    • Omary, M.B.1    Ku, N.O.2
  • 6
    • 85047681520 scopus 로고    scopus 로고
    • Keratinmediated resistance to stress and apoptosis in simple epithelial cells in relation to health and disease
    • Marceau N, Loranger A, Gilbert S, Daigle N, Champetier S. Keratinmediated resistance to stress and apoptosis in simple epithelial cells in relation to health and disease. Biochem Cell Biol 2001;79:543-555.
    • (2001) Biochem Cell Biol , vol.79 , pp. 543-555
    • Marceau, N.1    Loranger, A.2    Gilbert, S.3    Daigle, N.4    Champetier, S.5
  • 7
    • 0028865145 scopus 로고
    • Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant
    • Ku NO, Michie S, Oshima RG, Omary MB. Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant. J Cell Biol 1995;131:1303-1314.
    • (1995) J Cell Biol , vol.131 , pp. 1303-1314
    • Ku, N.O.1    Michie, S.2    Oshima, R.G.3    Omary, M.B.4
  • 9
    • 0031836071 scopus 로고    scopus 로고
    • Protein phosphatase inhibition in normal and keratin 8/18 assembly-incompetent mouse strains supports a functional role of keratin intermediate filaments in preserving hepatocyte integrity
    • Toivola DM, Omary MB, Ku NO, Peltola O, Baribault H, Eriksson JE. Protein phosphatase inhibition in normal and keratin 8/18 assembly-incompetent mouse strains supports a functional role of keratin intermediate filaments in preserving hepatocyte integrity. HEPATOLOGY 1998;28:116-128.
    • (1998) Hepatology , vol.28 , pp. 116-128
    • Toivola, D.M.1    Omary, M.B.2    Ku, N.O.3    Peltola, O.4    Baribault, H.5    Eriksson, J.E.6
  • 10
    • 0034599872 scopus 로고    scopus 로고
    • Keratin-dependent, epithelial resistance to tumor necrosis factor-induced apoptosis
    • Caulin C, Ware CF, Magin TM, Oshima RG. Keratin-dependent, epithelial resistance to tumor necrosis factor-induced apoptosis. J Cell Biol 2000;149:17-22.
    • (2000) J Cell Biol , vol.149 , pp. 17-22
    • Caulin, C.1    Ware, C.F.2    Magin, T.M.3    Oshima, R.G.4
  • 11
    • 0033843879 scopus 로고    scopus 로고
    • Cytokeratin 8 protects from hepatotoxicity, and its ratio to cytokeratin 18 determines the ability of hepatocytes to form Mallory bodies
    • Zatloukal K, Stumptner C, Lehner M, Denk H, Baribault H, Eshkind LG, Franke WW. Cytokeratin 8 protects from hepatotoxicity, and its ratio to cytokeratin 18 determines the ability of hepatocytes to form Mallory bodies. Am J Pathol 2000;156:1263-1274.
    • (2000) Am J Pathol , vol.156 , pp. 1263-1274
    • Zatloukal, K.1    Stumptner, C.2    Lehner, M.3    Denk, H.4    Baribault, H.5    Eshkind, L.G.6    Franke, W.W.7
  • 12
    • 0035921430 scopus 로고    scopus 로고
    • Simple epithelium keratins 8 and 18 provide resistance to Fas-mediated apoptosis. The protection occurs through a receptor-targeting modulation
    • Gilbert S, Loranger A, Daigle N, Marceau N. Simple epithelium keratins 8 and 18 provide resistance to Fas-mediated apoptosis. The protection occurs through a receptor-targeting modulation. J Cell Biol 2001;154:763-773.
    • (2001) J Cell Biol , vol.154 , pp. 763-773
    • Gilbert, S.1    Loranger, A.2    Daigle, N.3    Marceau, N.4
  • 13
  • 14
    • 0035942786 scopus 로고    scopus 로고
    • Keratin 8 mutations in patients with cryptogenic liver disease
    • Ku NO, Gish R, Wright TL, Omary MB. Keratin 8 mutations in patients with cryptogenic liver disease. N Engl J Med 2001;344:1580-1587.
    • (2001) N Engl J Med , vol.344 , pp. 1580-1587
    • Ku, N.O.1    Gish, R.2    Wright, T.L.3    Omary, M.B.4
  • 16
    • 0035851916 scopus 로고    scopus 로고
    • Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD
    • Inada H, Izawa I, Nishizawa M, Fujita E, Kiyono T, Takahashi T, Momoi T, et al. Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD. J Cell Biol 2001;155:415-426.
    • (2001) J Cell Biol , vol.155 , pp. 415-426
    • Inada, H.1    Izawa, I.2    Nishizawa, M.3    Fujita, E.4    Kiyono, T.5    Takahashi, T.6    Momoi, T.7
  • 17
    • 0036097410 scopus 로고    scopus 로고
    • Apoptosis and keratin intermediate filaments
    • Oshima RG. Apoptosis and keratin intermediate filaments. Cell Death Differ 2002;9:486-492.
    • (2002) Cell Death Differ , vol.9 , pp. 486-492
    • Oshima, R.G.1
  • 18
    • 0030770449 scopus 로고    scopus 로고
    • Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis
    • Caulin C, Salvesen GS, Oshima RG. Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis. J Cell Biol 1997;138:1379-1394.
    • (1997) J Cell Biol , vol.138 , pp. 1379-1394
    • Caulin, C.1    Salvesen, G.S.2    Oshima, R.G.3
  • 19
    • 0031455379 scopus 로고    scopus 로고
    • Apoptosis generates stable fragments of human type I keratins
    • Ku NO, Liao J, Omary MB. Apoptosis generates stable fragments of human type I keratins. J Biol Chem 1997;272:33197-33203.
    • (1997) J Biol Chem , vol.272 , pp. 33197-33203
    • Ku, N.O.1    Liao, J.2    Omary, M.B.3
  • 20
    • 0345040854 scopus 로고    scopus 로고
    • Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis
    • Leers MP, Kolgen W, Bjorklund V, Bergman T, Tribbick G, Persson B, Bjorklund P, et al. Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis. J Pathol 1999;187:567-572.
    • (1999) J Pathol , vol.187 , pp. 567-572
    • Leers, M.P.1    Kolgen, W.2    Bjorklund, V.3    Bergman, T.4    Tribbick, G.5    Persson, B.6    Bjorklund, P.7
  • 21
    • 0035920194 scopus 로고    scopus 로고
    • Effect of mutation and phosphorylation of type I keratins on their caspase-mediated degradation
    • Ku NO, Omary MB. Effect of mutation and phosphorylation of type I keratins on their caspase-mediated degradation. J Biol Chem 2001;276:26792-26798.
    • (2001) J Biol Chem , vol.276 , pp. 26792-26798
    • Ku, N.O.1    Omary, M.B.2
  • 22
    • 0034689052 scopus 로고    scopus 로고
    • Active caspases and cleaved cytokeratins are sequestered into cytoplasmic inclusions in TRAIL-induced apoptosis
    • MacFarlane M, Merrison W, Dinsdale D, Cohen GM. Active caspases and cleaved cytokeratins are sequestered into cytoplasmic inclusions in TRAIL-induced apoptosis. J Cell Biol 2000;148:1239-1254.
    • (2000) J Cell Biol , vol.148 , pp. 1239-1254
    • MacFarlane, M.1    Merrison, W.2    Dinsdale, D.3    Cohen, G.M.4
  • 23
    • 0025076790 scopus 로고
    • A single human keratin 18 gene is expressed in diverse epithelial cells of transgenic mice
    • Abe M, Oshima RG. A single human keratin 18 gene is expressed in diverse epithelial cells of transgenic mice. J Cell Biol 1990;111:1197-1206.
    • (1990) J Cell Biol , vol.111 , pp. 1197-1206
    • Abe, M.1    Oshima, R.G.2
  • 24
    • 0026627851 scopus 로고
    • Of mice and men: Genetic skin diseases of keratin
    • Fuchs E, Coulombe PA. Of mice and men: genetic skin diseases of keratin. Cell 1992;69:899-902.
    • (1992) Cell , vol.69 , pp. 899-902
    • Fuchs, E.1    Coulombe, P.A.2
  • 25
    • 0031032004 scopus 로고    scopus 로고
    • Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes
    • Amicone L, Spagnoli FM, Spath G, Giordano S, Tommasini C, Bernardini S, De Luca V, et al. Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes. EMBO J 1997;16:495-503.
    • (1997) EMBO J , vol.16 , pp. 495-503
    • Amicone, L.1    Spagnoli, F.M.2    Spath, G.3    Giordano, S.4    Tommasini, C.5    Bernardini, S.6    De Luca, V.7
  • 26
    • 0036073544 scopus 로고    scopus 로고
    • Hepatocytespecific inhibition of NF-kappaB leads to apoptosis after TNF treatment, but not after partial hepatectomy
    • Chaisson ML, Brooling JT, Ladiges W, Tsai S, Fausto N. Hepatocytespecific inhibition of NF-kappaB leads to apoptosis after TNF treatment, but not after partial hepatectomy. J Clin Invest 2002;110:193-202.
    • (2002) J Clin Invest , vol.110 , pp. 193-202
    • Chaisson, M.L.1    Brooling, J.T.2    Ladiges, W.3    Tsai, S.4    Fausto, N.5
  • 27
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A 1979;76:4350-4354.
    • (1979) Proc Natl Acad Sci U S A , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 28
    • 0032055050 scopus 로고    scopus 로고
    • Phosphorylation of human keratin 18 serine 33 regulates binding to 14-3-3 proteins
    • Ku NO, Liao J, Omary MB. Phosphorylation of human keratin 18 serine 33 regulates binding to 14-3-3 proteins. EMBO J 1998;17:1892-1906.
    • (1998) EMBO J , vol.17 , pp. 1892-1906
    • Ku, N.O.1    Liao, J.2    Omary, M.B.3
  • 29
    • 17344387813 scopus 로고    scopus 로고
    • Hepatic failure and liver cell damage in acute Wilson's disease involve CD95 (APO-1/Fas) mediated apoptosis
    • Strand S, Hofmann WJ, Grambihler A, Hug H, Volkmann M, Otto G, Wesch H, et al. Hepatic failure and liver cell damage in acute Wilson's disease involve CD95 (APO-1/Fas) mediated apoptosis. Nat Med 1998;4:588-593.
    • (1998) Nat Med , vol.4 , pp. 588-593
    • Strand, S.1    Hofmann, W.J.2    Grambihler, A.3    Hug, H.4    Volkmann, M.5    Otto, G.6    Wesch, H.7
  • 30
    • 0034060334 scopus 로고    scopus 로고
    • Apoptosis and liver disease
    • Rust C, Gores GJ. Apoptosis and liver disease. Am J Med 2000;108:567-574.
    • (2000) Am J Med , vol.108 , pp. 567-574
    • Rust, C.1    Gores, G.J.2
  • 31
    • 0032559341 scopus 로고    scopus 로고
    • A structural scaffolding of intermediate filaments in health and disease
    • Fuchs E, Cleveland DW. A structural scaffolding of intermediate filaments in health and disease. Science 1998;279:514-519.
    • (1998) Science , vol.279 , pp. 514-519
    • Fuchs, E.1    Cleveland, D.W.2
  • 32
    • 0037007011 scopus 로고    scopus 로고
    • Keratin binding to 14-3-3 proteins modulates keratin filaments and hepatocyte mitotic progression
    • Ku NO, Michie S, Resurreccion EZ, Broome RL, Omary MB. Keratin binding to 14-3-3 proteins modulates keratin filaments and hepatocyte mitotic progression. Proc Natl Acad Sci U S A 2002;99:4373-4378.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 4373-4378
    • Ku, N.O.1    Michie, S.2    Resurreccion, E.Z.3    Broome, R.L.4    Omary, M.B.5
  • 33
    • 0037192809 scopus 로고    scopus 로고
    • The intermediate filament protein keratin 8 is a novel cytoplasmic substrate for c-Jun N-terminal kinase
    • He T, Stepulak A, Holmstrom TH, Omary MB, Eriksson JE. The intermediate filament protein keratin 8 is a novel cytoplasmic substrate for c-Jun N-terminal kinase. J Biol Chem 2002;277:10767-10774.
    • (2002) J Biol Chem , vol.277 , pp. 10767-10774
    • He, T.1    Stepulak, A.2    Holmstrom, T.H.3    Omary, M.B.4    Eriksson, J.E.5
  • 34
    • 0032576580 scopus 로고    scopus 로고
    • Mutation of a major keratin phosphorylation site predisposes to hepatotoxic injury in transgenic mice
    • Ku NO, Michie SA, Soetikno RM, Resurreccion EZ, Broome RL, Omary MB. Mutation of a major keratin phosphorylation site predisposes to hepatotoxic injury in transgenic mice. J Cell Biol 1998;143:2023-2032.
    • (1998) J Cell Biol , vol.143 , pp. 2023-2032
    • Ku, N.O.1    Michie, S.A.2    Soetikno, R.M.3    Resurreccion, E.Z.4    Broome, R.L.5    Omary, M.B.6
  • 35
    • 0035110609 scopus 로고    scopus 로고
    • Anomalous apical plasma membrane phenotype in CK8-deficient mice indicates a novel role for intermediate filaments in the polarization of simple epithelia
    • Ameen NA, Figueroa Y, Salas PJ. Anomalous apical plasma membrane phenotype in CK8-deficient mice indicates a novel role for intermediate filaments in the polarization of simple epithelia. J Cell Sci 2001;114:563-575.
    • (2001) J Cell Sci , vol.114 , pp. 563-575
    • Ameen, N.A.1    Figueroa, Y.2    Salas, P.J.3


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