Modulation of Rho GTPase signaling regulates a switch between adipogenesis and myogenesis

Cell

Volumn 113, Issue 2, 2003, Pages 147-158

  Sordella, Raffaella ^a   Jiang, Wei ^a   Chen, Guang Chao ^a   Curto, Marcello ^a   Settleman, Jeffrey ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE; RHO KINASE; SOMATOMEDIN C;

ADIPOCYTE; ANIMAL CELL; ARTICLE; AUTORADIOGRAPHY; CELL DIFFERENTIATION; CELL FATE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; IMMUNOBLOTTING; LIPID STORAGE; MODULATION; MOUSE; MOUSE MUTANT; MUSCLE CELL; MUSCLE DEVELOPMENT; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0037453716     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(03)00271-X     Document Type: Article

References (32)

1. Allen M., Friedler A., Schon O., Bycroft M. The structure of an FF domain from human HYPA/FBP11. J. Mol. Biol. 323:2002;411-416.
2. Bains W., Ponte P., Blau H., Kedes L. Cardiac actin is the major actin gene product in skeletal muscle cell differentiation in vitro. Mol. Cell. Biol. 4:1984;1449-1453.
3. Begum N., Sandu O.A., Ito M., Lohmann S.M., Smolenski A. Active Rho kinase (ROK-alpha) associates with insulin receptor substrate-1 and inhibits insulin signaling in vascular smooth muscle cells. J. Biol. Chem. 277:2002;6214-6222.
4. Bickel P.E. Lipid rafts and insulin signaling. Am. J. Physiol. Endocrinol. Metab. 282:2002;E1-E10.
5. Brouns M.R., Matheson S.F., Hu K.-Q., Delalle I., Caviness V.S.J., Silver J., Bronson R.T., Settleman J. The adhesion signaling molecule p190 RhoGAP is required for morphogenetic processes in neural development. Development. 127:2000;4891-4903.
6. Brouns M.R., Matheson S.F., Settleman J. p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation. Nat. Cell Biol. 3:2001;361-367.
7. Burbelo P.D., Finegold A.A., Kozak C.A., Yamada Y., Takami H. Cloning, genomic organization and chromosomal assignment of the mouse p190-B gene. Biochim. Biophys. Acta. 1443:1998;203-210.
8. Carnac G., Primig M., Kitzmann M., Chafey P., Tuil D., Lamb N., Fernandez A. RhoA GTPase and serum response factor control selectively the expression of MyoD without affecting Myf5 in mouse myoblasts. Mol. Biol. Cell. 9:1998;1891-1902.
9. Charrasse S., Meriane M., Comunale F., Blangy A., Gauthier-Rouviere C. N-cadherin-dependent cell-cell contact regulates Rho GTPases and beta-catenin localization in mouse C2C12 myoblasts. J. Cell Biol. 158:2002;953-965.
10. Fujisawa K., Madaule P., Ishizaki T., Watanabe G., Bito H., Saito Y., Hall A., Narumiya S. Different regions of Rho determine Rho-selective binding of different classes of Rho target molecules. J. Biol. Chem. 273:1998;18943-18949.
11. Hall A. Rho GTPases and the actin cytoskeleton. Science. 279:1998;509-514.
12. Henning S.W., Galandrini R., Hall A., Cantrell D.A. The GTPase Rho has a critical regulatory role in thymus development. EMBO J. 16:1997;2397-2407.
13. Kontaridis M.I., Liu X., Zhang L., Bennett A.M. SHP-2 complex formation with the SHP-2 substrate-1 during C2C12 myogenesis. J. Cell Sci. 114:2001;2187-2198.
14. Lacalle R.A., Mira E., Gomez-Mouton C., Jimenez-Baranda S., Martinez A.C., Manes S. Specific SHP-2 partitioning in raft domains triggers integrin-mediated signaling via Rho activation. J. Cell Biol. 157:2002;277-289.
15. Luo L., Jan L., Jan Y.N. Small GTPases in axon outgrowth. Perspect. Dev. Neurobiol. 4:1996;199-204.
16. Maegawa H., Hasegawa M., Sugai S., Obata T., Ugi S., Morino K., Egawa K., Fujita T., Sakamoto T., Nishio Y.et al. Expression of a dominant negative SHP-2 in transgenic mice induces insulin resistance. J. Biol. Chem. 274:1999;30236-30243.
17. Marinissen M.J., Chiariello M., Gutkind J.S. Regulation of gene expression by the small GTPase Rho through the ERK6 (p38 gamma) MAP kinase pathway. Genes Dev. 15:2001;535-553.
18. Miki H., Yamauchi T., Suzuki R., Komeda K., Tsuchida A., Kubota N., Terauchi Y., Kamon J., Kaburagi Y., Matsui J.et al. Essential role of insulin receptor substrate 1 (IRS-1) and IRS-2 in adipocyte differentiation. Mol. Cell. Biol. 21:2001;2521-2532.
19. O'Brien S.P., Seipel K., Medley Q.G., Bronson R., Segal R., Streuli M. Skeletal muscle deformity and neuronal disorder in Trio exchange factor-deficient mouse embryos. Proc. Natl. Acad. Sci. USA. 97:2000;12074-12078.
20. O'Reilly A.M., Pluskey S., Shoelson S.E., Neel B.G. Activated mutants of SHP-2 preferentially induce elongation of Xenopus animal caps. Mol. Cell. Biol. 20:2000;299-311.
21. Reusch J.E., Colton L.A., Klemm D.J. CREB activation induces adipogenesis in 3T3-L1 cells. Mol. Cell. Biol. 20:2000;1008-1020.
22. Rosen E.D., Spiegelman B.M. Molecular regulation of adipogenesis. Annu. Rev. Cell Dev. Biol. 16:2000;145-171.
23. Settleman J. Rho GTPases in development. Prog. Mol. Subcell. Biol. 22:1999;201-229.
24. Sordella R., Classon M., Hu K.Q., Matheson S.F., Brouns M.R., Fine B., Zhang L., Takami H., Yamada Y., Settleman J. Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic development. Dev. Cell. 2:2002;553-565.
25. Sugai M., Hashimoto K., Kikuchi A., Inoue S., Okumura H., Matsumoto K., Goto Y., Ohgai H., Moriishi K., Syuto B.et al. Epidermal cell differentiation inhibitor ADP-ribosylates small GTP-binding proteins and induces hyperplasia of epidermis. J. Biol. Chem. 267:1992;2600-2604.
26. Symons M., Settleman J. Rho family GTPases. more than simple switches Trends Cell Biol. 10:2000;415-419.
27. Takano H., Komuro I., Oka T., Shiojima I., Hiroi Y., Mizuno T., Yazaki Y. The Rho family G proteins play a critical role in muscle differentiation. Mol. Cell. Biol. 18:1998;1580-1589.
28. Taya S., Inagaki N., Sengiku H., Makino H., Iwamatsu A., Urakawa I., Nagao K., Kataoka S., Kaibuchi K. Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF. J. Cell Biol. 155:2001;809-820.
29. Vincent S., Settleman J. Inhibition of RhoGAP activity is sufficient for the induction of Rho-mediated actin reorganization. Eur. J. Cell Biol. 78:1999;539-548.
30. Williams I.H., Polakis S.E. Differentiation of 3T3-L1 fibroblasts to adipocytes. The effect of indomethacin, prostaglandin E1 and cyclic AMP on the process of differentiation. Biochem. Biophys. Res. Commun. 77:1977;175-186.
31. Xu B., Bird V.G., Miller W.T. Substrate specificities of the insulin and insulin-like growth factor 1 receptor tyrosine kinase catalytic domains. J. Biol. Chem. 270:1995;29825-29830.
32. Zhao M., New L., Kravchenko V.V., Kato Y., Gram H., di Padova F., Olson E.N., Ulevitch R.J., Han J. Regulation of the MEF2 family of transcription factors by p38. Mol. Cell. Biol. 19:1999;21-30.