A two-year study with fibrillar β-amyloid (Aβ) immunization in aged canines: Effects on cognitive function and brain Aβ

Journal of Neuroscience

Volumn 28, Issue 14, 2008, Pages 3555-3566

  Head, Elizabeth ^a,b   Pop, Viorela ^b   Vasilevko, Vitaly ^a   Hill, MaryAnn ^a   Saing, Tommy ^a   Sarsoza, Floyd ^a   Nistor, Michaela ^a   Christie, Lori Ann ^a   Milton, Saskia ^a   Glabe, Charles ^a   Barrett, Edward ^c   Cribbs, David ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

Author keywords

Beagle; Executive function; Memory; Oligomers; Reversal learning; Spatial attention; Visual discrimination learning

Indexed keywords

ALUMINUM POTASSIUM SULFATE; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; OLIGOMER; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); PEPTIDE FRAGMENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIBODY TITER; ARTICLE; ATTENTION; BRAIN FUNCTION; BRAIN REGION; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DOG; DRUG FORMULATION; FEMALE; IMMUNIZATION; LEARNING; MAMMAL; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; SENILE PLAQUE; SPATIAL MEMORY; AGING; ANALYSIS OF VARIANCE; ANIMAL; ANIMAL BEHAVIOR; BRAIN; DECISION MAKING; DISCRIMINATION LEARNING; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOLOGY; LONGITUDINAL STUDY; MALE; MEMORY; METABOLISM; METHODOLOGY; NEUROFIBRILLARY TANGLE; NEUROPSYCHOLOGICAL TEST; PATHOLOGY; PHYSIOLOGY;

AGING; AMYLOID BETA-PROTEIN; ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; CHOICE BEHAVIOR; COGNITION; DISCRIMINATION LEARNING; DOGS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNIZATION; IMMUNIZATION SCHEDULE; LONGITUDINAL STUDIES; MALE; MEMORY; NEUROFIBRILLARY TANGLES; NEUROPSYCHOLOGICAL TESTS; PEPTIDE FRAGMENTS;

EID: 43649096717     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0208-08.2008     Document Type: Article

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