Eosinophils and allergic diseases of the gastrointestinal tract

Best Practice and Research: Clinical Gastroenterology

Volumn 22, Issue 3, 2008, Pages 455-479

  Bischoff, Stephan C ^b   Ulmer, Friedericke A ^a  

^a UNIVERSITY OF HOHENHEIM   (Germany)

^b NONE

Author keywords

eosinophil derived neurotoxin; eosinophilic gastroenteritis; eosinophilic oesophagitis; eosinophils; eotaxin; food allergy; interleukin 5

Indexed keywords

ANTIHISTAMINIC AGENT; BERTILIMUMAB; BUDESONIDE; CORTICOSTEROID; CROMOGLYCATE DISODIUM; EOTAXIN; FLUTICASONE; GLUCOCORTICOID; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GRAZAX; IMMUNOGLOBULIN E; IMMUNOLOGIC AGENT; INTERLEUKIN 3; INTERLEUKIN 5; INTERLEUKIN 5 ANTIBODY; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MEPOLIZUMAB; MONTELUKAST; RANTES;

ANAPHYLAXIS; ARTICLE; ATOPY; CELL ACTIVATION; CELL FUNCTION; CHEMOTAXIS; CLINICAL TRIAL; DESENSITIZATION; DRUG WITHDRAWAL; ELEMENTAL DIET; EOSINOPHIL; EOSINOPHILIA; EOSINOPHILIC COLITIS; EOSINOPHILIC ESOPHAGITIS; EOSINOPHILIC GASTROENTERITIS; EOSINOPHILIC GASTROINTESTINAL DISORDER; EOSINOPHILIC PROCTITIS; FOOD ALLERGY; GASTROINTESTINAL DISEASE; GASTROINTESTINAL INFECTION; GASTROINTESTINAL TRACT ALLERGY; GASTROINTESTINAL TUMOR; HUMAN; LABORATORY TEST; LYMPHOCYTE; MAST CELL; NUTRITIONAL INTOLERANCE; PATIENT COMPLIANCE; PROVOCATION TEST; SKIN TEST; UNSPECIFIED SIDE EFFECT;

EOSINOPHILIA; GASTROINTESTINAL DISEASES; HUMANS; HYPERSENSITIVITY;

EID: 43549106124     PISSN: 15216918     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpg.2007.11.010     Document Type: Article

References (134)

1. Food allergy caused by immunologic cross-reactions. Guideline of the German Association of Allergy and Clinical Immunology Allergo J 14 2004 48 59
2. T. Schafer E. Bohler S. Ruhdorfer Epidemiology of food allergy/food intolerance in adults: associations with other manifestations of atopy Allergy 56 2001 1172 1179
3. T. Zuberbier G. Edenharter M. Worm Prevalence of adverse reactions to food in Germany – a population study Allergy 59 2004 338 345
4. S. Bischoff S.E. Crowe Gastrointestinal food allergy: new insights into pathophysiology and clinical perspectives Gastroenterology 128 2005 1089 1113
5. P. Brandtzaeg Development and basic mechanisms of human gut immunity Nutr Rev 56 1998 S5 S18
6. H.G. Boman Innate immunity and the normal microflora Immunol Rev 173 2000 5 16
7. M. Zasloff Antimicrobial peptides in health and disease N Engl J Med 347 2002 1199 1200
8. T. Ganz Defensins: antimicrobial peptides of innate immunity Nat Rev Immunol 3 2003 710 720
9. R. Medzhitov C. Janeway Jr. Innate immunity N Engl J Med 343 2000 338 344
10. J. Wedemeyer M. Tsai S.J. Galli Roles of mast cells and basophils in innate and acquired immunity Curr Opin Immunol 12 2000 624 631
11. H. Wagner Toll meets bacterial CpG-DNA Immunity 14 2001 499 502
12. H.L. Weiner A. Friedman A. Miller Oral tolerance: immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens Annu Rev Immunol 12 1994 809 837
13. S.C. Bischoff Food allergies Curr Gastroenterol Rep 8 2006 374 382
14. R.R. Coombs The Jack Pepys Lecture. The hypersensitivity reactions – some personal reflections Clin Exp Allergy 22 1992 673 680
15. P.A. Eigenmann C.P. Frossard The T lymphocyte in food-allergy disorders Curr Opin Allergy Clin Immunol 3 2003 199 203
16. J.E. de Vries The role of IL-13 and its receptor in allergy and inflammatory responses J Allergy Clin Immunol 102 1998 165 169
17. S.C. Bischoff G. Sellge A. Lorentz IL-4 enhances proliferation and mediator release in mature human mast cells Proc Natl Acad Sci USA 96 1999 8080 8085
18. J.E. de Vries J.M. Carballido G. Aversa Receptors and cytokines involved in allergic TH2 cell responses J Allergy Clin Immunol 103 1999 S492 S496
19. S.P. Hogan P.S. Foster M.E. Rothenberg Experimental analysis of eosinophil-associated gastrointestinal diseases Curr Opin Allergy Clin Immunol 2 2002 239 248
20. U. Bengtsson T.W. Knutson L. Knutson Eosinophil cationic protein and histamine after intestinal challenge in patients with cows' milk intolerance J Allergy Clin Immunol 100 1997 216 221
21. S.C. Bischoff J. Grabowsky M.P. Manns Quantification of inflammatory mediators in stool samples of patients with inflammatory bowel disorders and controls Dig Dis Sci 42 1997 394 403
22. J. Santos C. Bayarri E. Saperas Characterisation of immune mediator release during the immediate response to segmental mucosal challenge in the jejunum of patients with food allergy Gut 45 1999 553 558
23. D. Schwab S. Muller T. Aigner Functional and morphologic characterization of eosinophils in the lower intestinal mucosa of patients with food allergy Am J Gastroenterol 98 2003 1525 1534
24. K.J. Kelly A.J. Lazenby P.C. Rowe Eosinophilic esophagitis attributed to gastroesophageal reflux: improvement with an amino acid-based formula Gastroenterology 109 1995 1503 1512
25. A. Straumann H.P. Spichtin L. Grize Natural history of primary eosinophilic esophagitis: a follow-up of 30 adult patients for up to 11.5 years Gastroenterology 125 2003 1660 1669
26. H.A. Sampson Food allergy JAMA 278 1997 1888 1894
27. J.M. Spergel T. Andrews T.F. Brown-Whitehorn Treatment of eosinophilic esophagitis with specific food elimination diet directed by a combination of skin prick and patch tests Ann Allergy Asthma Immunol 95 2005 336 343
28. M.E. Rothenberg Eosinophilia N Engl J Med 338 1998 1592 1600
29. M.M. Teixeira T.J. Williams P.G. Hellewell Mechanisms and pharmacological manipulation of eosinophil accumulation in vivo Trends Pharmacol Sci 16 1995 418 423
30. S.P. Hogan M.E. Rothenberg Review article: the eosinophil as a therapeutic target in gastrointestinal disease Aliment Pharmacol Ther 20 2004 1231 1240
31. M.E. Rothenberg A. Mishra E.B. Brandt Gastrointestinal eosinophils Immunol Rev 179 2001 139 155
32. M.E. Rothenberg Gastrointestinal eosinophils Allergy 56 Suppl 67 2001 21 22
33. C. Blanchard S. Durual M. Estienne Eotaxin-3/CCL26 gene expression in intestinal epithelial cells is up-regulated by interleukin-4 and interleukin-13 via the signal transducer and activator of transcription 6 Int J Biochem Cell Biol 37 2005 2559 2573
34. R.J. Pleass M.L. Lang M.A. Kerr IgA is a more potent inducer of NADPH oxidase activation and degranulation in blood eosinophils than IgE Mol Immunol 44 2007 1401 1408
35. S. Lantero G. Alessandri D. Spallarossa Stimulation of eosinophil IgE low-affinity receptor leads to increased adhesion molecule expression and cell migration Eur Respir J 16 2000 940 946
36. S.P. Hogan M.E. Rothenberg E. Forbes Chemokines in eosinophil-associated gastrointestinal disorders Curr Allergy Asthma Rep 4 2004 74 82
37. G.T. Furuta E.E.S. Nieuwenhuis J. Karhausen Eosinophils alter colonic epithelial barrier function: role for major basic protein Am J Physiol Gastrointest Liver Physiol 289 2005 G890 G897
38. D.Y. Leung T. Bieber Atopic dermatitis Lancet 361 2003 151 160
39. J.M. James Respiratory manifestations of food allergy Pediatrics 111 2003 1625 1630
40. R. Rokaite L. Labanauskas Gastrointestinal disorders in children with atopic dermatitis Medicina (Kaunas) 41 2005 837 845
41. J. van Odijk C.G. Peterson S. Ahlstedt Measurements of eosinophil activation before and after food challenges in adults with food hypersensitivity Int Arch Allergy Immunol 140 2006 334 341
42. A. Fasano I. Berti T. Gerarduzzi Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study Arch Intern Med 163 2003 286 292
43. A. Fasano Celiac disease – how to handle a clinical chameleon N Engl J Med 348 2003 2568 2570
44. R.J. Rona T. Keil C. Summers The prevalence of food allergy: a meta-analysis J Allergy Clin Immunol 120 2007 638 646
45. M. Eggesbo R. Halvorsen K. Tambs Prevalence of parentally perceived adverse reactions to food in young children Pediatr Allergy Immunol 10 1999 122 132
46. R.K. Woods R.M. Stoney J. Raven Reported adverse food reactions overestimate true food allergy in the community Eur J Clin Nutr 56 2002 31 36
47. R. Rhodius K. Wickens S. Cheng A comparison of two skin test methodologies and allergens from two different manufacturers Ann Allergy Asthma Immunol 88 2002 374 379
48. E. Young M.D. Stoneham A. Petruckevitch A population study of food intolerance Lancet 343 1994 1127 1130
49. H.A. Aardoom R.A. Hirasing R.J. Rona Food intolerance (food hypersensitivity) and chronic complaints in children: the parents' perception Eur J Pediatr 156 1997 110 112
50. H.A. Sampson Update on food allergy J Allergy Clin Immunol 113 2004 805 819
51. M. Steinke A. Fiocchi V. Kirchlechner Perceived food allergy in children in 10 European nations. A randomised telephone survey Int Arch Allergy Immunol 143 2007 290 295
52. N.J. Talley R.G. Shorter S.F. Phillips Eosinophilic gastroenteritis: a clinicopathological study of patients with disease of the mucosa, muscle layer, and subserosal tissues Gut 31 1990 54 58
53. A.R. Naylor Eosinophilic gastroenteritis Scott Med J 35 1990 163 165
54. J.R. Guajardo L.M. Plotnick J.M. Fende Eosinophil-associated gastrointestinal disorders: a world-wide-web based registry J Pediatr 141 2002 576 581
55. A. Host Frequency of cows' milk allergy in childhood Ann Allergy Asthma Immunol 89 2002 33 37
56. J.M. Spergel A.S. Paller Atopic dermatitis and the atopic march J Allergy Clin Immunol 112 2003 S118 S127
57. B. Niggemann B. Sielaff K. Beyer Outcome of double-blind, placebo-controlled food challenge tests in 107 children with atopic dermatitis Clin Exp Allergy 29 1999 91 96
58. S.H. Sicherer A. Munoz-Furlong H.A. Sampson Prevalence of peanut and tree nut allergy in the United States determined by means of a random digit dial telephone survey: a 5-year follow-up study J Allergy Clin Immunol 112 2003 1203 1207
59. J. Grundy S. Matthews B. Bateman Rising prevalence of allergy to peanut in children: data from 2 sequential cohorts J Allergy Clin Immunol 110 2002 784 789
60. M.E. Rothenberg A. Mishra M.H. Collins Pathogenesis and clinical features of eosinophilic esophagitis J Allergy Clin Immunol 108 2001 891 894
61. S.R. Orenstein T.M. Shalaby C. Di Lorenzo The spectrum of pediatric eosinophilic esophagitis beyond infancy: a clinical series of 30 children Am J Gastroenterol 95 2000 1422 1430
62. V.L. Fox S. Nurko G.T. Furuta Eosinophilic esophagitis: it's not just kid's stuff Gastrointest Endosc 56 2002 260 270
63. M.I. Fogg E. Ruchelli J.M. Spergel Pollen and eosinophilic esophagitis J Allergy Clin Immunol 112 2003 796 797
64. D. Simon H. Marti P. Heer Eosinophilic esophagitis is frequently associated with IgE-mediated allergic airway diseases J Allergy Clin Immunol 115 2005 1090 1092
65. J.E. Teitelbaum V.L. Fox F.J. Twarog Eosinophilic esophagitis in children: immunopathological analysis and response to fluticasone propionate Gastroenterology 122 2002 1216 1225
66. E.H. Dauer D.K. Freese M. El Youssef Clinical characteristics of eosinophilic esophagitis in children Ann Otol Rhinol Laryngol 114 2005 827 833
67. J.M. Spergel J. Beausoleil T. Brown-Whitehorn Authors' response to detection of causative foods by skin prick and atopy patch tests in patients with eosinophilic esophagitis: things are not what they seem Ann Allergy Asthma Immunol 96 2006 376 378
68. S.V. Walsh D.A. Antonioli H. Goldman Allergic esophagitis in children: a clinicopathological entity Am J Surg Pathol 23 1999 390 396
69. C. Blanchard N. Wang K.F. Stringer Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis J Clin Invest 116 2006 536 547
70. A. Straumann M. Bauer B. Fischer Idiopathic eosinophilic esophagitis is associated with a T(H)2-type allergic inflammatory response J Allergy Clin Immunol 108 2001 954 961
71. A. Mishra M.E. Rothenberg Intratracheal IL-13 induces eosinophilic esophagitis by an IL-5, eotaxin-1, and STAT6-dependent mechanism Gastroenterology 125 2003 1419 1427
72. J.Z. Bullock J.M. Villanueva C. Blanchard Interplay of adaptive th2 immunity with eotaxin-3/c-C chemokine receptor 3 in eosinophilic esophagitis J Pediatr Gastroenterol Nutr 45 2007 22 31
73. A. Straumann J. Kristl S. Conus Cytokine expression in healthy and inflamed mucosa: probing the role of eosinophils in the digestive tract Inflamm Bowel Dis 11 2005 720 726
74. C.A. Liacouras Eosinophilic esophagitis: treatment in 2005 Curr Opin Gastroenterol 22 2006 147 152
75. S.N. Sgouros C. Bergele A. Mantides Eosinophilic esophagitis in adults: what is the clinical significance? Endoscopy 38 2006 515 520
76. S.E. Attwood T.C. Smyrk T.R. Demeester Esophageal eosinophilia with dysphagia. A distinct clinicopathologic syndrome Dig Dis Sci 38 1993 109 116
77. S.N. Sgouros C. Bergele A. Mantides Eosinophilic esophagitis in adults: a systematic review Eur J Gastroenterol Hepatol 18 2006 211 217
78. V.L. Fox S. Nurko J.E. Teitelbaum High-resolution EUS in children with eosinophilic ‘allergic’ esophagitis Gastrointest Endosc 57 2003 30 36
79. K. Onbasi A.Z. Sin B. Doganavsargil Eosinophil infiltration of the oesophageal mucosa in patients with pollen allergy during the season Clin Exp Allergy 35 2005 1423 1431
80. J.R. Parfitt J.C. Gregor N.G. Suskin Eosinophilic esophagitis in adults: distinguishing features from gastroesophageal reflux disease: a study of 41 patients Mod Pathol 19 2006 90 96
81. A. Straumann H.P. Spichtin K.A. Bucher Eosinophilic esophagitis: red on microscopy, white on endoscopy Digestion 70 2004 109 116
82. C.A. Liacouras W.J. Wenner K. Brown Primary eosinophilic esophagitis in children: successful treatment with oral corticosteroids J Pediatr Gastroenterol Nutr 26 1998 380 385
83. C.A. Liacouras J.M. Spergel E. Ruchelli Eosinophilic esophagitis: a 10-year experience in 381 children Clin Gastroenterol Hepatol 3 2005 1198 1206
84. S. Khan Eosinophilic gastroenteritis Best Pract Res Clin Gastroenterol 19 2005 177 198
85. K. Beyer R. Castro A. Birnbaum Human milk-specific mucosal lymphocytes of the gastrointestinal tract display a TH2 cytokine profile J Allergy Clin Immunol 109 2002 707 713
86. J.S. Jaffe S.P. James G.E. Mullins Evidence for an abnormal profile of interleukin-4 (IL-4), IL-5, and gamma-interferon (gamma-IFN) in peripheral blood T cells from patients with allergic eosinophilic gastroenteritis J Clin Immunol 14 1994 299 309
87. A. Mishra S.P. Hogan E.B. Brandt An etiological role for aeroallergens and eosinophils in experimental esophagitis J Clin Invest 107 2001 83 90
88. M.N. Kweon H. Kiyono Eosinophilic gastroenteritis: a problem of the mucosal immune system? Curr Allergy Asthma Rep 3 2003 79 85
89. K.J. Kelly Eosinophilic gastroenteritis J Pediatr Gastroenterol Nutr 30 Suppl 2000 S28 S35
90. P. Alexander S. Jacob V. Paul Laparoscopy in eosinophilic jejunitis presenting as subacute bowel obstruction: a case report Trop Gastroenterol 24 2003 97 98
91. T. Uenishi C. Sakata S. Tanaka Eosinophilic enteritis presenting as acute intestinal obstruction: a case report and review of the literature Dig Surg 20 2003 326 329
92. R. Chaudhary R.K. Shrivastava H.G. Mukhopadhyay Eosinophilic gastritis—an unusual cause of gastric outlet obstruction Indian J Gastroenterol 20 2001 110
93. H.L. Tan N. Sithasanan P. Foley The successful medical management of severe duodenal strictures secondary to eosinophilic gastroenteritis in an infant Pediatr Surg Int 19 2003 562 563
94. T. Siahanidou H. Mandyla D. Dimitriadis Eosinophilic gastroenteritis complicated with perforation and intussusception in a neonate J Pediatr Gastroenterol Nutr 32 2001 335 337
95. D. Tran L. Salloum C. Tshibaka Eosinophilic gastroenteritis mimicking acute appendicitis Am Surg 66 2000 990 992
96. M. Jimenez-Saenz J.L. Villar-Rodriguez Y. Torres Biliary tract disease: a rare manifestation of eosinophilic gastroenteritis Dig Dis Sci 48 2003 624 627
97. R. Madhotra M.A. Eloubeidi J.T. Cunningham Eosinophilic gastroenteritis masquerading as ampullary adenoma J Clin Gastroenterol 34 2002 240 242
98. M.G. Schappi V.V. Smith P.J. Milla Eosinophilic myenteric ganglionitis is associated with functional intestinal obstruction Gut 52 2003 752 755
99. C.M. Lee C.S. Changchien P.C. Chen Eosinophilic gastroenteritis: 10 years experience Am J Gastroenterol 88 1993 70 74
100. F.C. Huang S.F. Ko S.C. Huang Eosinophilic gastroenteritis with perforation mimicking intussusception J Pediatr Gastroenterol Nutr 33 2001 613 615
101. N. Katsumi Y. Yamaguchi T. Yamato Multiple ulcerative lesions of the stomach: a rare case of eosinophilic gastroenteritis Gastrointest Endosc 56 2002 762 764
102. J.A. Solis-Herruzo B. de Cuenca M.T. Munoz-Yague Laparoscopic findings in serosal eosinophilic gastroenteritis. Report of two cases Endoscopy 20 1988 152 153
103. A. Nowak-Wegrzyn H.A. Sampson R.A. Wood Food protein-induced enterocolitis syndrome caused by solid food proteins Pediatrics 111 2003 829 835
104. J. Kokkonen M. Haapalahti K. Laurila T.J. Karttunen Cow's milk protein-sensitive enteropathy at school age J Pediatr 139 2001 797 803
105. S.H. Sicherer P.A. Eigenmann H.A. Sampson Clinical features of food protein-induced enterocolitis syndrome J Pediatr 133 1998 214 219
106. H.L. Chung J.B. Hwang J.J. Park Expression of transforming growth factor beta1, transforming growth factor type I and II receptors, and TNF-alpha in the mucosa of the small intestine in infants with food protein-induced enterocolitis syndrome J Allergy Clin Immunol 109 2002 150 154
107. J.A. Walker-Smith Diagnostic criteria for gastrointestinal food allergy in childhood Clin Exp Allergy 25 Suppl 1 1995 20 22
108. K.F. Murray D.L. Christie Dietary protein intolerance in infants with transient methemoglobinemia and diarrhea J Pediatr 122 1993 90 92
109. E. Redondo-Cerezo M.J. Cabello Y. Gonzalez Eosinophilic gastroenteritis: our recent experience: one-year experience of atypical onset of an uncommon disease Scand J Gastroenterol 36 2001 1358 1360
110. S. Venkataraman B.S. Ramakrishna M. Mathan Eosinophilic gastroenteritis—an Indian experience Indian J Gastroenterol 17 1998 148 149
111. S.H. Sicherer Clinical aspects of gastrointestinal food allergy in childhood Pediatrics 111 2003 1609 1616
112. J. Maloney A. Nowak-Wegrzyn Educational clinical case series for pediatric allergy and immunology: allergic proctocolitis, food protein-induced enterocolitis syndrome and allergic eosinophilic gastroenteritis with protein-losing gastroenteropathy as manifestations of non-IgE-mediated cows' milk allergy Pediatr Allergy Immunol 18 2007 360 367
113. J.W. Chang T.C. Wu K.S. Wang Colon mucosal pathology in infants under three months of age with diarrhea disorders J Pediatr Gastroenterol Nutr 35 2002 387 390
114. J.F. Swart K. Ultee Rectal bleeding in a preterm infant as a symptom of allergic colitis Eur J Pediatr 162 2003 55 56
115. M.E. Rothenberg Eosinophilic gastrointestinal disorders (EGID) J Allergy Clin Immunol 113 2004 11 28
116. W. Pumberger G. Pomberger W. Geissler Proctocolitis in breast fed infants: a contribution to differential diagnosis of haematochezia in early childhood Postgrad Med J 77 2001 252 254
117. A.M. Lake Food-induced eosinophilic proctocolitis J Pediatr Gastroenterol Nutr 30 Suppl 2000 S58 S60
118. J.B. Hwang M.H. Park Y.N. Kang Advanced criteria for clinicopathological diagnosis of food protein-induced proctocolitis J Korean Med Sci 22 2007 213 217
119. A. Mehl C. Rolinck-Werninghaus U. Staden The atopy patch test in the diagnostic workup of suspected food-related symptoms in children J Allergy Clin Immunol 118 2006 923 929
120. S.C. Bischoff J. Mayer J. Wedemeyer Colonoscopic allergen provocation (COLAP): a new diagnostic approach for gastrointestinal food allergy Gut 40 1997 745 753
121. C. Gore C.G. Peterson P. Kissen Urinary eosinophilic protein X, atopy, and symptoms suggestive of allergic disease at 3 years of age J Allergy Clin Immunol 112 2003 702 708
122. H. Majamaa S. Laine A. Miettinen Eosinophil protein X and eosinophil cationic protein as indicators of intestinal inflammation in infants with atopic eczema and food allergy Clin Exp Allergy 29 1999 1502 1506
123. K.M. Saarinen A. Sarnesto E. Savilahti Markers of inflammation in the feces of infants with cows' milk allergy Pediatr Allergy Immunol 13 2002 188 194
124. J.M. Spergel Eosinophilic oesophagitis and pollen Clin Exp Allergy 35 2005 1421 1422
125. S.R. Durham B. Riis Grass allergen tablet immunotherapy relieves individual seasonal eye and nasal symptoms, including nasal blockage Allergy 62 2007 954 957
126. M.J. Chen C.H. Chu S.C. Lin Eosinophilic gastroenteritis: clinical experience with 15 patients World J Gastroenterol 9 2003 2813 2816
127. M. Chehade M.S. Magid S. Mofidi Allergic eosinophilic gastroenteritis with protein-losing enteropathy: intestinal pathology, clinical course, and long-term follow-up J Pediatr Gastroenterol Nutr 42 2006 516 521
128. S.S. Aceves R. Dohil R.O. Newbury Topical viscous budesonide suspension for treatment of eosinophilic esophagitis J Allergy Clin Immunol 116 2005 705 706
129. D.M. Thompson A.S. Arora Y. Romero Eosinophilic esophagitis: its role in aerodigestive tract disorders Otolaryngol Clin North Am 39 2006 205 221
130. J.K. Garrett S.C. Jameson B. Thomson Anti-interleukin-5 (mepolizumab) therapy for hypereosinophilic syndromes J Allergy Clin Immunol 113 2004 115 119
131. Y.J. Kim C. Prussin B. Martin Rebound eosinophilia after treatment of hypereosinophilic syndrome and eosinophilic gastroenteritis with monoclonal anti-IL-5 antibody SCH55700 J Allergy Clin Immunol 114 2004 1449 1455
132. M.L. Stein M.H. Collins J.M. Villanueva Anti-IL-5 (mepolizumab) therapy for eosinophilic esophagitis J Allergy Clin Immunol 118 2006 1312 1319
133. C. Ding J. Li X. Zhang Bertilimumab Cambridge Antibody Technology Group Curr Opin Investig Drugs 5 2004 1213 1218
134. P.J. Barnes Th2 cytokines and asthma: an introduction Respir Res 2 2001 64 65