메뉴 건너뛰기




Volumn 125, Issue 5, 2003, Pages 1419-1427

Intratracheal IL-13 Induces Eosinophilic Esophagitis by an IL-5, Eotaxin-1, and STAT6-Dependent Mechanism

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; BROXURIDINE; CYTOKINE; EOTAXIN; INTERLEUKIN 13; INTERLEUKIN 5; STAT6 PROTEIN; UNCLASSIFIED DRUG;

EID: 0242406890     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gastro.2003.07.007     Document Type: Article
Times cited : (358)

References (56)
  • 2
    • 0021708547 scopus 로고
    • Intraepithelial eosinophils in endoscopic biopsies of adults with reflux esophagitis
    • Brown LF, Goldman H, Antonioli DA. Intraepithelial eosinophils in endoscopic biopsies of adults with reflux esophagitis. Am J Surg Pathol 1984;8:899-905.
    • (1984) Am J Surg Pathol , vol.8 , pp. 899-905
    • Brown, L.F.1    Goldman, H.2    Antonioli, D.A.3
  • 4
    • 0033064254 scopus 로고    scopus 로고
    • Food allergy. Part 1: Immunopathogenesis and clinical disorders
    • Sampson HA. Food allergy. Part 1: Immunopathogenesis and clinical disorders. J Allergy Clin Immunol 1999;103:717-728.
    • (1999) J Allergy Clin Immunol , vol.103 , pp. 717-728
    • Sampson, H.A.1
  • 5
    • 0036673054 scopus 로고    scopus 로고
    • Eosinophilic esophagitis: It's notjust kid's stuff
    • Fox VL, Nurko S, Furuta GT. Eosinophilic esophagitis: it's notjust kid's stuff. Gastrointest Endosc 2002;56:260-270.
    • (2002) Gastrointest Endosc , vol.56 , pp. 260-270
    • Fox, V.L.1    Nurko, S.2    Furuta, G.T.3
  • 10
    • 0028793765 scopus 로고
    • Eosinophilic esophagitis attributed to gastroesophageal reflux: Improvement with an amino acid-based formula
    • Kelly KJ, Lazenby AJ, Rowe PC, Yardley JH, Perman JA, Sampson HA. Eosinophilic esophagitis attributed to gastroesophageal reflux: improvement with an amino acid-based formula. Gastroenterology 1995;109:1503-1512.
    • (1995) Gastroenterology , vol.109 , pp. 1503-1512
    • Kelly, K.J.1    Lazenby, A.J.2    Rowe, P.C.3    Yardley, J.H.4    Perman, J.A.5    Sampson, H.A.6
  • 11
    • 0031948265 scopus 로고    scopus 로고
    • Primary eosinophilic esophagitis in children: Successful treatment with oral corticosteroids
    • Liacouras CA, Wenner WJ, Brown K, Ruchelli E. Primary eosinophilic esophagitis in children: successful treatment with oral corticosteroids. J Pediatr Gastroenterol Nutr 1998;26:380-385.
    • (1998) J Pediatr Gastroenterol Nutr , vol.26 , pp. 380-385
    • Liacouras, C.A.1    Wenner, W.J.2    Brown, K.3    Ruchelli, E.4
  • 12
    • 0036174564 scopus 로고    scopus 로고
    • The use of skin prick test and patch tests to identify causative foods in eosinophilic esophagitis
    • Spergel JM, Beausoleil JL, Mascarenbas M, Liacouras CA. The use of skin prick test and patch tests to identify causative foods in eosinophilic esophagitis. J Allergy Clin Immunol 2002;109:368-368.
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 368-368
    • Spergel, J.M.1    Beausoleil, J.L.2    Mascarenbas, M.3    Liacouras, C.A.4
  • 13
    • 0031922807 scopus 로고    scopus 로고
    • Eosinophils in the esophagus: Acid is not the only cause
    • Furuta GT. Eosinophils in the esophagus: acid is not the only cause. J Pediatr Gastroenterol Nutr 1998;26:468-471.
    • (1998) J Pediatr Gastroenterol Nutr , vol.26 , pp. 468-471
    • Furuta, G.T.1
  • 14
    • 0035174173 scopus 로고    scopus 로고
    • An etiological role for aeroallergens and eosinophils in experimental esophagitis
    • Mishra A, Hogan SP, Brandt EB, Rothenberg ME. An etiological role for aeroallergens and eosinophils in experimental esophagitis. J Clin Invest 2001;107:83-90.
    • (2001) J Clin Invest , vol.107 , pp. 83-90
    • Mishra, A.1    Hogan, S.P.2    Brandt, E.B.3    Rothenberg, M.E.4
  • 16
    • 0026643596 scopus 로고
    • Interleukin-5, eosinophils, and disease
    • Sanderson CJ. Interleukin-5, eosinophils, and disease. Blood 1992;79:3101-3109.
    • (1992) Blood , vol.79 , pp. 3101-3109
    • Sanderson, C.J.1
  • 17
    • 0029148025 scopus 로고
    • Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo
    • Collins PD, Marleau S, Griffiths-Johnson DA, Jose PJ, Williams TJ. Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo. J Exp Med 1995;182:1169-1174.
    • (1995) J Exp Med , vol.182 , pp. 1169-1174
    • Collins, P.D.1    Marleau, S.2    Griffiths-Johnson, D.A.3    Jose, P.J.4    Williams, T.J.5
  • 19
    • 0035218441 scopus 로고    scopus 로고
    • Idiopathic eosinophilic esophagitis is associated with a T(H)2-type allergic inflammatory response
    • Straumann A, Bauer M, Fischer B, Blaser K, Simon HU. Idiopathic eosinophilic esophagitis is associated with a T(H)2-type allergic inflammatory response. J Allergy Clin Immunol 2001;108:954-961.
    • (2001) J Allergy Clin Immunol , vol.108 , pp. 954-961
    • Straumann, A.1    Bauer, M.2    Fischer, B.3    Blaser, K.4    Simon, H.U.5
  • 20
  • 21
    • 0035141618 scopus 로고    scopus 로고
    • IL-12/IL-13 axis in allergic asthma
    • Wills-Karp M. IL-12/IL-13 axis in allergic asthma. J Allergy Clin Immunol 2001;107:9-18.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 9-18
    • Wills-Karp, M.1
  • 22
    • 0036032996 scopus 로고    scopus 로고
    • Effects of eosinophils on mast cells: A new pathway for the perpetuation of allergic inflammation
    • Piliponsky A, Gleich G, Bar I, Levi-Schaffer F. Effects of eosinophils on mast cells: a new pathway for the perpetuation of allergic inflammation. Mol Immunol 2002;38:1369.
    • (2002) Mol Immunol , vol.38 , pp. 1369
    • Piliponsky, A.1    Gleich, G.2    Bar, I.3    Levi-Schaffer, F.4
  • 24
    • 0031278414 scopus 로고    scopus 로고
    • Skin-homing, CLA+ memory T cells are activated in atopic dermatitis and regulate IgE by an IL-13-dominated cytokine pattern: IgG4 counter-regulation by CLA-memory T cells
    • Akdis M, Akdis CA, Weigl L, Disch R, Blaser K. Skin-homing, CLA+ memory T cells are activated in atopic dermatitis and regulate IgE by an IL-13-dominated cytokine pattern: IgG4 counter-regulation by CLA-memory T cells. J Immunol 1997;159:4611-4619.
    • (1997) J Immunol , vol.159 , pp. 4611-4619
    • Akdis, M.1    Akdis, C.A.2    Weigl, L.3    Disch, R.4    Blaser, K.5
  • 25
    • 0030906932 scopus 로고    scopus 로고
    • Increased levels of IL-13 mRNA, but not IL-4 mRNA, are found in vivo in peripheral blood mononuclear cells (PBMC) of patients with atopic dermatitis (AD)
    • Katagiri K, Itami S, Hatano Y, Takayasu S. Increased levels of IL-13 mRNA, but not IL-4 mRNA, are found in vivo in peripheral blood mononuclear cells (PBMC) of patients with atopic dermatitis (AD). Clin Exp Immunol 1997;108:289-294.
    • (1997) Clin Exp Immunol , vol.108 , pp. 289-294
    • Katagiri, K.1    Itami, S.2    Hatano, Y.3    Takayasu, S.4
  • 26
    • 0031569973 scopus 로고    scopus 로고
    • Associations between IL-13 and IL-4 (mRNA and protein), vascular cell adhesion molecule-1 expression, and the infiltration of eosinophils, macrophages, and T cells in allergen-induced latephase cutaneous reactions in atopic subjects
    • Ying S, Meng Q, Barata LT, Robinson DS, Durham SR, Kay AB. Associations between IL-13 and IL-4 (mRNA and protein), vascular cell adhesion molecule-1 expression, and the infiltration of eosinophils, macrophages, and T cells in allergen-induced latephase cutaneous reactions in atopic subjects. J Immunol 1997;158:5050-5057.
    • (1997) J Immunol , vol.158 , pp. 5050-5057
    • Ying, S.1    Meng, Q.2    Barata, L.T.3    Robinson, D.S.4    Durham, S.R.5    Kay, A.B.6
  • 28
    • 0030999135 scopus 로고    scopus 로고
    • Nasal mast cells in perennial allergic rhinitis exhibit increased expression of the Fc epsilonRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells
    • Pawankar R, Okuda M, Yssel H, Okumura K, Ra C. Nasal mast cells in perennial allergic rhinitis exhibit increased expression of the Fc epsilonRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells. J Clin Invest 1997;99:1492-1499.
    • (1997) J Clin Invest , vol.99 , pp. 1492-1499
    • Pawankar, R.1    Okuda, M.2    Yssel, H.3    Okumura, K.4    Ra, C.5
  • 29
    • 0030877164 scopus 로고    scopus 로고
    • IL-4 and IL-13 expression in chronic sinusitis: Relationship with cellular infiltrate and effect of topical corticosteroid treatment
    • Al Ghamdi K, Ghaffar O, Small P, Frenkiel S, Hamid Q. IL-4 and IL-13 expression in chronic sinusitis: relationship with cellular infiltrate and effect of topical corticosteroid treatment. J Otolaryngol 1997;26:160-166.
    • (1997) J Otolaryngol , vol.26 , pp. 160-166
    • Al Ghamdi, K.1    Ghaffar, O.2    Small, P.3    Frenkiel, S.4    Hamid, Q.5
  • 30
    • 0033560126 scopus 로고    scopus 로고
    • Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
    • Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, Zhang Y, Elias JA. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 1999;103:779-788.
    • (1999) J Clin Invest , vol.103 , pp. 779-788
    • Zhu, Z.1    Homer, R.J.2    Wang, Z.3    Chen, Q.4    Geba, G.P.5    Wang, J.6    Zhang, Y.7    Elias, J.A.8
  • 31
    • 0033104696 scopus 로고    scopus 로고
    • Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells
    • Li L, Xia Y, Nguyen A, Lai YH, Feng L, Mosmann TR, Lo D. Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells. J Immunol 1999;162:2477-2487.
    • (1999) J Immunol , vol.162 , pp. 2477-2487
    • Li, L.1    Xia, Y.2    Nguyen, A.3    Lai, Y.H.4    Feng, L.5    Mosmann, T.R.6    Lo, D.7
  • 35
    • 0031028633 scopus 로고    scopus 로고
    • Targeted disruption of the chemokine eotaxin partially reduces antigen-induced tissue eosinophilia
    • Rothenberg ME, MacLean JA, Pearlman E, Luster AD, Leder P. Targeted disruption of the chemokine eotaxin partially reduces antigen-induced tissue eosinophilia. J Exp Med 1997;185:785-790.
    • (1997) J Exp Med , vol.185 , pp. 785-790
    • Rothenberg, M.E.1    MacLean, J.A.2    Pearlman, E.3    Luster, A.D.4    Leder, P.5
  • 36
    • 0032746179 scopus 로고    scopus 로고
    • Fundamental signals regulate eosinophil homing to the gastrointestinal tract
    • Mishra A, Hogan SP, Lee JJ, Foster PS, Rothenberg ME. Fundamental signals regulate eosinophil homing to the gastrointestinal tract. J Clin Invest 1999;103:1719-1727.
    • (1999) J Clin Invest , vol.103 , pp. 1719-1727
    • Mishra, A.1    Hogan, S.P.2    Lee, J.J.3    Foster, P.S.4    Rothenberg, M.E.5
  • 37
    • 0027239843 scopus 로고
    • Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes
    • Finkelman FD, Madden KB, Morris SC, Holmes JM, Boiani N, Katona IM, Maliszewski CR. Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes. J Immunol 1993;151:1235-1244.
    • (1993) J Immunol , vol.151 , pp. 1235-1244
    • Finkelman, F.D.1    Madden, K.B.2    Morris, S.C.3    Holmes, J.M.4    Boiani, N.5    Katona, I.M.6    Maliszewski, C.R.7
  • 40
    • 0032007351 scopus 로고    scopus 로고
    • IL-13, IL-4Rα, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis
    • Urban JF Jr, Noben-Trauth N, Donaldson DD, Madden KB, Morris SC, Collins M, Finkelman FD. IL-13, IL-4Rα, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis. Immunity 1998;8:255-264.
    • (1998) Immunity , vol.8 , pp. 255-264
    • Urban Jr., J.F.1    Noben-Trauth, N.2    Donaldson, D.D.3    Madden, K.B.4    Morris, S.C.5    Collins, M.6    Finkelman, F.D.7
  • 41
    • 0033925799 scopus 로고    scopus 로고
    • Systemically derived large intestinal CD4(+) Th2 cells play a central role in STAT6-mediated allergic diarrhea
    • Kweon MN, Yamamoto M, Kajiki M, Takahashi I, Kiyono H. Systemically derived large intestinal CD4(+) Th2 cells play a central role in STAT6-mediated allergic diarrhea. J Clin Invest 2000;106:199-206.
    • (2000) J Clin Invest , vol.106 , pp. 199-206
    • Kweon, M.N.1    Yamamoto, M.2    Kajiki, M.3    Takahashi, I.4    Kiyono, H.5
  • 42
    • 0036850908 scopus 로고    scopus 로고
    • Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells
    • Heller F, Fuss IJ, Nieuwenhuis EE, Blumberg RS, Strober W. Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells. Immunity 2002;17:629-638.
    • (2002) Immunity , vol.17 , pp. 629-638
    • Heller, F.1    Fuss, I.J.2    Nieuwenhuis, E.E.3    Blumberg, R.S.4    Strober, W.5
  • 44
    • 0032960929 scopus 로고    scopus 로고
    • Severity of esophageal eosinophilia predicts response to conventional gastroesophageal reflux therapy
    • Ruchelli E, Wenner W, Voytek T, Brown K, Liacouras C. Severity of esophageal eosinophilia predicts response to conventional gastroesophageal reflux therapy. Pediatr Dev Pathol 1999;2:15-18.
    • (1999) Pediatr Dev Pathol , vol.2 , pp. 15-18
    • Ruchelli, E.1    Wenner, W.2    Voytek, T.3    Brown, K.4    Liacouras, C.5
  • 46
    • 0032482159 scopus 로고    scopus 로고
    • Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT)6-deficient mice
    • Akimoto T, Numata F, Tamura M, Takata Y, Higashida N, Takashi T, Takeda K, Akira S. Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT)6-deficient mice. J Exp Med 1998;187:1537-1542.
    • (1998) J Exp Med , vol.187 , pp. 1537-1542
    • Akimoto, T.1    Numata, F.2    Tamura, M.3    Takata, Y.4    Higashida, N.5    Takashi, T.6    Takeda, K.7    Akira, S.8
  • 47
    • 0030817146 scopus 로고    scopus 로고
    • Full thickness eosinophilia in oesophageal leiomyomatosis and idiopathic eosinophilic oesophagitis. A common allergic inflammatory profile?
    • Nicholson AG, Li D, Pastorino U, Goldstraw P, Jeffery PK. Full thickness eosinophilia in oesophageal leiomyomatosis and idiopathic eosinophilic oesophagitis. A common allergic inflammatory profile? J Pathol 1997;183:233-236.
    • (1997) J Pathol , vol.183 , pp. 233-236
    • Nicholson, A.G.1    Li, D.2    Pastorino, U.3    Goldstraw, P.4    Jeffery, P.K.5
  • 48
    • 0034612322 scopus 로고    scopus 로고
    • A critical role for eotaxin in experimental oral antigen-induced eosinophilic gastrointestinal allergy
    • Hogan SP, Mishra A, Brandt EB, Foster PS, Rothenberg ME. A critical role for eotaxin in experimental oral antigen-induced eosinophilic gastrointestinal allergy. Proc Natl Acad Sci U S A 2000;97:6681-6686.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 6681-6686
    • Hogan, S.P.1    Mishra, A.2    Brandt, E.B.3    Foster, P.S.4    Rothenberg, M.E.5
  • 49
    • 0032574902 scopus 로고    scopus 로고
    • Eosinophilia
    • Rothenberg ME. Eosinophilia. N Engl J Med 1998;338:1592-1600.
    • (1998) N Engl J Med , vol.338 , pp. 1592-1600
    • Rothenberg, M.E.1
  • 50
    • 0035104951 scopus 로고    scopus 로고
    • Mast cells, basophils, and eosinophils: Distinct but overlapping pathways for recruitment
    • Bochner BS, Schleimer RP. Mast cells, basophils, and eosinophils: distinct but overlapping pathways for recruitment. Immunol Rev 2001;179:5-15.
    • (2001) Immunol Rev , vol.179 , pp. 5-15
    • Bochner, B.S.1    Schleimer, R.P.2
  • 52
    • 0032696339 scopus 로고    scopus 로고
    • Chemokines and asthma: Redundancy of function or a coordinated effort?
    • Lukacs NW, Oliveira SH, Hogaboam CM. Chemokines and asthma: redundancy of function or a coordinated effort? J Clin Invest 1999;104:995-999.
    • (1999) J Clin Invest , vol.104 , pp. 995-999
    • Lukacs, N.W.1    Oliveira, S.H.2    Hogaboam, C.M.3
  • 53
    • 0035075850 scopus 로고    scopus 로고
    • Fluticasone in eosinophilic corrugated ringed esophagus
    • Langdon DE. Fluticasone in eosinophilic corrugated ringed esophagus. Am J Gastroenterol 2001;96:926-927.
    • (2001) Am J Gastroenterol , vol.96 , pp. 926-927
    • Langdon, D.E.1
  • 56
    • 0033604599 scopus 로고    scopus 로고
    • Therapeutic strategies for allergic diseases
    • Barnes PJ. Therapeutic strategies for allergic diseases. Nature 1999;402:B31-B38.
    • (1999) Nature , vol.402
    • Barnes, P.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.