Proline derived spirobarbiturates as highly effective β-turn mimetics incorporating polar and functionalizable constraint elements

Journal of Organic Chemistry

Volumn 73, Issue 9, 2008, Pages 3608-3611

  Lomlim, Luelak ^a   Einsiedel, Juergen ^a   Heinemann, Frank W ^a   Meyer, Karsten ^a   Gmeiner, Peter ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMIMETICS; SPECTROSCOPIC ANALYSIS; SYNTHESIS (CHEMICAL); X RAY CRYSTALLOGRAPHY;

CONSTRAINT ELEMENTS; IMIDE FUNCTIONS; MOLECULAR SCAFFOLDS; SPIROCYCLIC NEUROPEPTIDE ANALOGS;

PEPTIDES;

BARBITURIC ACID DERIVATIVE; IMIDE; NEUROPEPTIDE; PROLINE DERIVATIVE;

ACIDITY; ARTICLE; CHEMICAL STRUCTURE; HYDROPHILICITY; MOLECULAR MIMICRY; SOLID PHASE SYNTHESIS; SPECTROSCOPY; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

BARBITURATES; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PIPERIDINES; PROLINE; SPIRO COMPOUNDS;

EID: 43449130074     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo702573z     Document Type: Article

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