Evaluation of lactam-bridged neurotensin analogues adjusting ψ(Pro 10) close to the experimentally derived bioactive conformation of NT(8-13)

Journal of Medicinal Chemistry

Volumn 47, Issue 22, 2004, Pages 5587-5590

  Bittermann, Holger ^a   Einsiedel, Jürgen ^a   Hübner, Harald ^a   Gmeiner, Peter ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LACTAM DERIVATIVE; NEUROTENSIN; NEUROTENSIN DERIVATIVE; NEUROTENSIN RECEPTOR; NEUROTENSIN[8-13] DERIVATIVE; NEUROTENSIN[8-13][11 N METHYLTYROSINE]; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CORPUS STRIATUM; DRUG CONFORMATION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; NONHUMAN; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SWINE;

ANIMALS; BINDING, COMPETITIVE; LACTAMS; MOLECULAR CONFORMATION; MOLECULAR MIMICRY; NEUROTENSIN; OLIGOPEPTIDES; PROLINE; PROTEIN STRUCTURE, SECONDARY; RADIOLIGAND ASSAY; RECEPTORS, NEUROTENSIN; STEREOISOMERISM; SWINE; TYROSINE;

EID: 6044260114     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm049644y     Document Type: Article

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