Mechanism of action of Drosophila Reaper in mammalian cells: Reaper globally inhibits protein synthesis and induces apoptosis independent of mitochondrial permeability

Cell Death and Differentiation

Volumn 11, Issue 8, 2004, Pages 800-811

  Tait, S W G ^a   Werner, A B ^a   de Vries, E ^a   Borst, J ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

Cytochrome c; IPA; Mammalian cells; Mitochondria; Reaper

Indexed keywords

CASPASE; CYTOCHROME C; INHIBITOR OF APOPTOSIS PROTEIN; PROTEASOME; REAPER PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DROSOPHILA; ENZYME ACTIVATION; ENZYME DEGRADATION; HUMAN; HUMAN CELL; INSECT CELL; MAMMAL CELL; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN SYNTHESIS INHIBITION; TRANSLATION REGULATION;

AMINO ACID MOTIFS; ANIMALS; APOPTOSIS; CELLS, CULTURED; COS CELLS; CYTOCHROMES C; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; HELA CELLS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MITOCHONDRIA; PROTEIN BINDING;

INSECTA; MAMMALIA;

EID: 4344680248     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401410     Document Type: Article

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