-
1
-
-
33746414426
-
Cytokine responses to CpG DNA in human leukocytes
-
Agren J., Thiemermann C., Foster S. J., Wang J. E. and Aasen A. O. (2006): Cytokine responses to CpG DNA in human leukocytes. Scand. J. Immunol., 64, 61-68.
-
(2006)
Scand. J. Immunol
, vol.64
, pp. 61-68
-
-
Agren, J.1
Thiemermann, C.2
Foster, S.J.3
Wang, J.E.4
Aasen, A.O.5
-
2
-
-
0038604293
-
Bacterial DNA evokes epithelial IL-8 production by a MAPK-dependent, NF-κB-independent pathway
-
Akhtar M., Watson J. L., Nazli A. and McKay D. M. (2003): Bacterial DNA evokes epithelial IL-8 production by a MAPK-dependent, NF-κB-independent pathway. FASEB J., 17, 1319-1321.
-
(2003)
FASEB J
, vol.17
, pp. 1319-1321
-
-
Akhtar, M.1
Watson, J.L.2
Nazli, A.3
McKay, D.M.4
-
3
-
-
0037290876
-
Mammalian Toll-like receptors
-
Akira S. (2003): Mammalian Toll-like receptors. Curr. Opin. Immunol., 15, 5-11.
-
(2003)
Curr. Opin. Immunol
, vol.15
, pp. 5-11
-
-
Akira, S.1
-
4
-
-
3142724031
-
Toll-like receptor signalling
-
Akira S. and Takeda K. (2004): Toll-like receptor signalling. Nat. Rev. Immunol., 4, 499-511.
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
5
-
-
33748478585
-
Neutrophil signaling pathways activated by bacterial DNA stimulation
-
Alvarez M. E., Fuxman Bass J. I., Gefner J. R., Fernandez Calotti P. X., Costas M., Coso O. M., Gamberale R., Vermeulen M.E., Salamone G., Martinez D., Tanos T. and Trevani A. S. (2006): Neutrophil signaling pathways activated by bacterial DNA stimulation. J. Immunol., 177, 4037-4046.
-
(2006)
J. Immunol
, vol.177
, pp. 4037-4046
-
-
Alvarez, M.E.1
Fuxman Bass, J.I.2
Gefner, J.R.3
Fernandez Calotti, P.X.4
Costas, M.5
Coso, O.M.6
Gamberale, R.7
Vermeulen, M.E.8
Salamone, G.9
Martinez, D.10
Tanos, T.11
Trevani, A.S.12
-
6
-
-
0141727730
-
Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes
-
Baldus S., Heaschen C., Meinertz T., Zeiher A. M., Eiserich J. P., Munzel T., Simoons M. L. and Hamm C. W. (2003): Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes. Circulation, 108, 1440-1445.
-
(2003)
Circulation
, vol.108
, pp. 1440-1445
-
-
Baldus, S.1
Heaschen, C.2
Meinertz, T.3
Zeiher, A.M.4
Eiserich, J.P.5
Munzel, T.6
Simoons, M.L.7
Hamm, C.W.8
-
7
-
-
29244450802
-
Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA
-
Barton G. M., Kagan J. C. and Medzhitov R. (2006): Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA. Nat. Immunol., 7, 49-56.
-
(2006)
Nat. Immunol
, vol.7
, pp. 49-56
-
-
Barton, G.M.1
Kagan, J.C.2
Medzhitov, R.3
-
8
-
-
0035979192
-
Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition
-
Bauer S., Kisching C. J., Hacker H., Redecke V., Hausmann S., Akira S., Wagner H. and Lipford G. B. (2001): Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition. Proc. Natl. Acad. Sci. USA, 98, 9237-9242.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9237-9242
-
-
Bauer, S.1
Kisching, C.J.2
Hacker, H.3
Redecke, V.4
Hausmann, S.5
Akira, S.6
Wagner, H.7
Lipford, G.B.8
-
9
-
-
10344246592
-
TLRs govern neutrophil activity in aspergillosis
-
Bellocchio S., Moretti S., Perruccio K., Fallarino F., Bozza S., Montagnoli C., Mosci P., Lipford G. B., Pitzurra L. and Romani L. (2004): TLRs govern neutrophil activity in aspergillosis. J. Immunol., 173, 7406-7415.
-
(2004)
J. Immunol
, vol.173
, pp. 7406-7415
-
-
Bellocchio, S.1
Moretti, S.2
Perruccio, K.3
Fallarino, F.4
Bozza, S.5
Montagnoli, C.6
Mosci, P.7
Lipford, G.B.8
Pitzurra, L.9
Romani, L.10
-
10
-
-
33745585567
-
Toxoplasma gondii inhibits Toll-like receptor 4 ligand-induced mobilization of intracellular tumor necrosis factor alpha to the surface of mouse peritoneal neutrophils
-
Bennouna S., Sukhumavasi W. and Denkers E. Y. (2006): Toxoplasma gondii inhibits Toll-like receptor 4 ligand-induced mobilization of intracellular tumor necrosis factor alpha to the surface of mouse peritoneal neutrophils. Infect. Immun., 74, 4274-4281.
-
(2006)
Infect. Immun
, vol.74
, pp. 4274-4281
-
-
Bennouna, S.1
Sukhumavasi, W.2
Denkers, E.Y.3
-
11
-
-
3142654210
-
Inferences, questions and possibilities in Toll-like receptor signalling
-
Beutler B. (2004): Inferences, questions and possibilities in Toll-like receptor signalling. Nature, 430, 257-263.
-
(2004)
Nature
, vol.430
, pp. 257-263
-
-
Beutler, B.1
-
12
-
-
0027986079
-
A non-radioisotopic method for tracing neutrophils in vivo using 5′-bromo-2′-deoxyuridine
-
Bicknell S., van Eden S., Hayashi S., Hards J., English D. and Hogg J. C. (1994): A non-radioisotopic method for tracing neutrophils in vivo using 5′-bromo-2′-deoxyuridine. Am. J. Respir. Cell. Mol. Biol., 10, 16-23.
-
(1994)
Am. J. Respir. Cell. Mol. Biol
, vol.10
, pp. 16-23
-
-
Bicknell, S.1
van Eden, S.2
Hayashi, S.3
Hards, J.4
English, D.5
Hogg, J.C.6
-
13
-
-
0022540321
-
CpG rich islands and the function of DNA methylation
-
Bird A. P. (1986): CpG rich islands and the function of DNA methylation. Nature, 321, 209-213.
-
(1986)
Nature
, vol.321
, pp. 209-213
-
-
Bird, A.P.1
-
14
-
-
0023472826
-
CpG islands as gene markers in the vertebrate nucleus
-
Bird A. P. (1987): CpG islands as gene markers in the vertebrate nucleus. Trends Genet., 3, 342-347.
-
(1987)
Trends Genet
, vol.3
, pp. 342-347
-
-
Bird, A.P.1
-
15
-
-
3242728901
-
Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways
-
Bjorkbacka H., Kunjathoor V. V., Moore K. J., Koehn S., Ordija C. M., Lee M. A., Means T., Halmen K., Luster A. D., Golenback D. T. and Freeman M. W. (2004): Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways. Nat. Med., 10, 416-421.
-
(2004)
Nat. Med
, vol.10
, pp. 416-421
-
-
Bjorkbacka, H.1
Kunjathoor, V.V.2
Moore, K.J.3
Koehn, S.4
Ordija, C.M.5
Lee, M.A.6
Means, T.7
Halmen, K.8
Luster, A.D.9
Golenback, D.T.10
Freeman, M.W.11
-
16
-
-
34247484007
-
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling
-
Brinkmann M. M., Spooner E., Hoebe K., Beutler B., Ploegh H. L. and Kim Y-M. (2007): The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling. J. Cell Biol., 177, 265-275.
-
(2007)
J. Cell Biol
, vol.177
, pp. 265-275
-
-
Brinkmann, M.M.1
Spooner, E.2
Hoebe, K.3
Beutler, B.4
Ploegh, H.L.5
Kim, Y.-M.6
-
17
-
-
0037019329
-
Widespread coronary inflammation in unstable angina
-
Buffon A., Biasucci L. M., Liuzzo G., D'Onofrio G., Crea F. and Maseri A. (2002): Widespread coronary inflammation in unstable angina. N. Engl. J. Med., 347, 5-12.
-
(2002)
N. Engl. J. Med
, vol.347
, pp. 5-12
-
-
Buffon, A.1
Biasucci, L.M.2
Liuzzo, G.3
D'Onofrio, G.4
Crea, F.5
Maseri, A.6
-
18
-
-
34547814686
-
Leishmania major induces distinct neutrophil phenotypes in mice that are resistant or susceptible to infection
-
Charmoy M., Megnekou R., Allenbach C., Zweifel C., Perez C., Monnat K., Breton M., Ronet C., Launois P. and Tacchini-Cottier F. (2007): Leishmania major induces distinct neutrophil phenotypes in mice that are resistant or susceptible to infection. J. Leukoc. Biol., 82, 288-299.
-
(2007)
J. Leukoc. Biol
, vol.82
, pp. 288-299
-
-
Charmoy, M.1
Megnekou, R.2
Allenbach, C.3
Zweifel, C.4
Perez, C.5
Monnat, K.6
Breton, M.7
Ronet, C.8
Launois, P.9
Tacchini-Cottier, F.10
-
19
-
-
0033637315
-
DNA-PKcs is required for activation of innate immunity by immunostimulatory DNA
-
Chu W., Gong X., Li Z., Takabayashi K., Ouyang H., Chen Y., Lois A., Chen D. J., Li G. C., Karim M. and Raz E. (2000): DNA-PKcs is required for activation of innate immunity by immunostimulatory DNA. Cell, 103, 909-918.
-
(2000)
Cell
, vol.103
, pp. 909-918
-
-
Chu, W.1
Gong, X.2
Li, Z.3
Takabayashi, K.4
Ouyang, H.5
Chen, Y.6
Lois, A.7
Chen, D.J.8
Li, G.C.9
Karim, M.10
Raz, E.11
-
20
-
-
0141886169
-
Inflammatory cytokine expression is independent of the c-Jun N-terminal kinase/AP-1 signaling cascade in human neutrophils
-
Cloutier A., Ear T., Borissevitch O., Larivée P. and McDonald P. P. (2003): Inflammatory cytokine expression is independent of the c-Jun N-terminal kinase/AP-1 signaling cascade in human neutrophils. J. Immunol., 171, 3751-3761.
-
(2003)
J. Immunol
, vol.171
, pp. 3751-3761
-
-
Cloutier, A.1
Ear, T.2
Borissevitch, O.3
Larivée, P.4
McDonald, P.P.5
-
21
-
-
19944430901
-
Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin
-
Coban C., Ishii K.J., Kawai T., Hemmi H., Sato S., Uematzu S., Yamamoto M., Takeuchi O., Itagaki S., Kumar N., Horii T. and Akira S. (2005): Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin. J. Exp. Med., 201, 19-25.
-
(2005)
J. Exp. Med
, vol.201
, pp. 19-25
-
-
Coban, C.1
Ishii, K.J.2
Kawai, T.3
Hemmi, H.4
Sato, S.5
Uematzu, S.6
Yamamoto, M.7
Takeuchi, O.8
Itagaki, S.9
Kumar, N.10
Horii, T.11
Akira, S.12
-
22
-
-
0026795415
-
Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products
-
Colotta F., Re F., Polentarutti N., Sozzani S. and Mantovani A. (1992): Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products. Blood, 80, 2012-2020.
-
(1992)
Blood
, vol.80
, pp. 2012-2020
-
-
Colotta, F.1
Re, F.2
Polentarutti, N.3
Sozzani, S.4
Mantovani, A.5
-
23
-
-
0029934754
-
Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides
-
Cowdery J. S., Chase J. H., Yi A. K. and Krieg A. M. (1996): Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides. J. Immunol., 156, 4570-4575.
-
(1996)
J. Immunol
, vol.156
, pp. 4570-4575
-
-
Cowdery, J.S.1
Chase, J.H.2
Yi, A.K.3
Krieg, A.M.4
-
24
-
-
0033038486
-
Intra-articularly localized bacterial DNA containing CpG motifs induces arthritis
-
Deng G. M., Nilsson I. M., Verdrengh M., Collins L. V. and Tarkowski A. (1999): Intra-articularly localized bacterial DNA containing CpG motifs induces arthritis. Nat. Med., 5, 702-705.
-
(1999)
Nat. Med
, vol.5
, pp. 702-705
-
-
Deng, G.M.1
Nilsson, I.M.2
Verdrengh, M.3
Collins, L.V.4
Tarkowski, A.5
-
25
-
-
6344241187
-
CpG oligodeoxynucleotides stimulate protective innate immunity against pulmonary Klebsiella infection
-
Deng J. C., Moore T. A., Newstead M. W., Zeng X., Krieg A. M. and Standiford T. J. (2004): CpG oligodeoxynucleotides stimulate protective innate immunity against pulmonary Klebsiella infection. J. Immunol., 173, 5148-5155.
-
(2004)
J. Immunol
, vol.173
, pp. 5148-5155
-
-
Deng, J.C.1
Moore, T.A.2
Newstead, M.W.3
Zeng, X.4
Krieg, A.M.5
Standiford, T.J.6
-
26
-
-
0037066041
-
Expression of Toll-like receptors in human atherosclerotic lesions: A possible pathway for plaque activation
-
Edfeldt K., Swedenborg J., Hansson G. K. and Yan Z. O. (2002): Expression of Toll-like receptors in human atherosclerotic lesions: a possible pathway for plaque activation. Circulation, 105, 1158-1161.
-
(2002)
Circulation
, vol.105
, pp. 1158-1161
-
-
Edfeldt, K.1
Swedenborg, J.2
Hansson, G.K.3
Yan, Z.O.4
-
27
-
-
33750374367
-
Inhibition of K+ efflux prevents mitochondrial dysfunction, and suppresses caspase-3-, apoptosis-inducing factor-, and endonuclease G-mediated constitutive apoptosis in human neutrophils
-
El Kebir D., József L., Khreiss, T. and Filep J. G. (2006): Inhibition of K+ efflux prevents mitochondrial dysfunction, and suppresses caspase-3-, apoptosis-inducing factor-, and endonuclease G-mediated constitutive apoptosis in human neutrophils. Cell. Signal., 18, 2302-2313.
-
(2006)
Cell. Signal
, vol.18
, pp. 2302-2313
-
-
El Kebir, D.1
József, L.2
Khreiss, T.3
Filep, J.G.4
-
28
-
-
34250884498
-
Aspirin-triggered lipoxins override the apoptosis-delaying action of serum amyloid A in human neutrophils: A novel mechanism for resolution of inflammation
-
El Kebir D., József L., Pan W., Petasis N. A., Serhan C. N. and Filep J. G. (2007): Aspirin-triggered lipoxins override the apoptosis-delaying action of serum amyloid A in human neutrophils: a novel mechanism for resolution of inflammation. J. Immunol., 179, 616-622.
-
(2007)
J. Immunol
, vol.179
, pp. 616-622
-
-
El Kebir, D.1
József, L.2
Pan, W.3
Petasis, N.A.4
Serhan, C.N.5
Filep, J.G.6
-
29
-
-
0029796250
-
Cytokine-treated human neutrophils contain inducible nitric oxide synthase that produces nitration of ingested bacteria
-
Evans T. J., Buttery L. D. K., Carpenter A., Springall D. R., Polak J. M. and Cohen J. (1996): Cytokine-treated human neutrophils contain inducible nitric oxide synthase that produces nitration of ingested bacteria. Proc. Natl. Acad. Sci. USA, 93, 9553-9558.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9553-9558
-
-
Evans, T.J.1
Buttery, L.D.K.2
Carpenter, A.3
Springall, D.R.4
Polak, J.M.5
Cohen, J.6
-
30
-
-
0032534062
-
Peroxynitrite mediates IL-8 gene expression and production in lipopolysaccharide-stimulated human whole blood
-
Filep J. G., Beauchamp M., Baron C. and Paquette Y. (1998): Peroxynitrite mediates IL-8 gene expression and production in lipopolysaccharide-stimulated human whole blood. J. Immunol., 161, 5656-5662.
-
(1998)
J. Immunol
, vol.161
, pp. 5656-5662
-
-
Filep, J.G.1
Beauchamp, M.2
Baron, C.3
Paquette, Y.4
-
31
-
-
14844362908
-
Inhibition of neutrophil apoptosis by TLR agonists in whole blood: Involvement of the phosphoinositide 3-kinase/Akt and NF-κB signaling pathways, leading to increased levels of Mcl-1, A1, and phosphorylated Bad
-
Francois S., El Benna J., Dang P. M., Pedruzzi E., Gougerot-Pocidalo M.-E. and Elbim C. (2005): Inhibition of neutrophil apoptosis by TLR agonists in whole blood: involvement of the phosphoinositide 3-kinase/Akt and NF-κB signaling pathways, leading to increased levels of Mcl-1, A1, and phosphorylated Bad. J. Immunol., 174, 3633-3642.
-
(2005)
J. Immunol
, vol.174
, pp. 3633-3642
-
-
Francois, S.1
El Benna, J.2
Dang, P.M.3
Pedruzzi, E.4
Gougerot-Pocidalo, M.-E.5
Elbim, C.6
-
32
-
-
0025903905
-
Tumor necrosis factor alpha mediates lethal activity of killed Gram-negative and Gram-positive bacteria in D-galactosamine-treated mice
-
Freudenberg M. A. and Galanos C. (1991): Tumor necrosis factor alpha mediates lethal activity of killed Gram-negative and Gram-positive bacteria in D-galactosamine-treated mice. Infect. Immun., 59, 2110-2115.
-
(1991)
Infect. Immun
, vol.59
, pp. 2110-2115
-
-
Freudenberg, M.A.1
Galanos, C.2
-
33
-
-
0037108899
-
Protein nitration is predominantly mediated by peroxynitrite-dependent pathway in cultured human leukocytes
-
Galinanes M. and Matata B. M. (2002): Protein nitration is predominantly mediated by peroxynitrite-dependent pathway in cultured human leukocytes. Biochem. J., 367, 467-473.
-
(2002)
Biochem. J
, vol.367
, pp. 467-473
-
-
Galinanes, M.1
Matata, B.M.2
-
34
-
-
2342557323
-
Delay of neutrophil apoptosis in acute coronary syndromes
-
Garlichs C. D., Eskafi S., Cicha I., Schmeisser A., Walzog B., Raaz D., Stunpf C., Yilmaz A., Bremer J., Ludwig J. and Daniel W. G. (2004): Delay of neutrophil apoptosis in acute coronary syndromes. J. Leukoc. Biol., 75, 828-835.
-
(2004)
J. Leukoc. Biol
, vol.75
, pp. 828-835
-
-
Garlichs, C.D.1
Eskafi, S.2
Cicha, I.3
Schmeisser, A.4
Walzog, B.5
Raaz, D.6
Stunpf, C.7
Yilmaz, A.8
Bremer, J.9
Ludwig, J.10
Daniel, W.G.11
-
35
-
-
2442445450
-
Inflammatory resolution: New opportunities for drug discovery
-
Gilroy D. W., Lawrence T., Perretti M. and Rossi A. G. (2004): Inflammatory resolution: new opportunities for drug discovery. Nat. Rev. Drug Discov., 3, 401-416.
-
(2004)
Nat. Rev. Drug Discov
, vol.3
, pp. 401-416
-
-
Gilroy, D.W.1
Lawrence, T.2
Perretti, M.3
Rossi, A.G.4
-
36
-
-
0029039816
-
Cell acidification in apoptosis: Granulocyte colony-stimulating factor delays programmed cell death in neutrophils by up-regulating the vacuolar H(+)-ATPase
-
Gottlieb R. A., Giesing H. A., Zhu J. Y., Engler R. L. and Babior B. M. (1995): Cell acidification in apoptosis: granulocyte colony-stimulating factor delays programmed cell death in neutrophils by up-regulating the vacuolar H(+)-ATPase. Proc. Natl. Acad. Sci. USA, 92, 5965-5968.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5965-5968
-
-
Gottlieb, R.A.1
Giesing, H.A.2
Zhu, J.Y.3
Engler, R.L.4
Babior, B.M.5
-
37
-
-
0042346153
-
Repetitive elements in mammalian telomeres suppress bacterial DNA-induced immune activation
-
Gursel I., Gursel M., Yamada H, Ishii K. J., Takeshita F. and Klinman D. M. (2003): Repetitive elements in mammalian telomeres suppress bacterial DNA-induced immune activation. J. Immunol., 171, 1393-1400.
-
(2003)
J. Immunol
, vol.171
, pp. 1393-1400
-
-
Gursel, I.1
Gursel, M.2
Yamada, H.3
Ishii, K.J.4
Takeshita, F.5
Klinman, D.M.6
-
38
-
-
0036226045
-
Activation of the immune system by bacterial CpG-DNA
-
Häcker G., Redecke V. and Häcker H. (2002): Activation of the immune system by bacterial CpG-DNA. Immunology, 105, 245-251.
-
(2002)
Immunology
, vol.105
, pp. 245-251
-
-
Häcker, G.1
Redecke, V.2
Häcker, H.3
-
39
-
-
0028025205
-
Selection of antisense oligonucleotides on the basis of genomic frequency of the target sequence
-
Han J., Zhu Z., Hsu C. and Finley W. H. (1994): Selection of antisense oligonucleotides on the basis of genomic frequency of the target sequence. Antisense Res. Dev., 4, 53-65.
-
(1994)
Antisense Res. Dev
, vol.4
, pp. 53-65
-
-
Han, J.1
Zhu, Z.2
Hsu, C.3
Finley, W.H.4
-
40
-
-
33745571976
-
The immune response in atherosclerosis: A double-edged sword
-
Hansson G. K. and Libby P. (2006): The immune response in atherosclerosis: a double-edged sword. Nat. Rev. Immunol., 6, 508-519.
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 508-519
-
-
Hansson, G.K.1
Libby, P.2
-
41
-
-
0034650517
-
Mechanism and function of a newly identified CpG DNA motif in human primary B cells
-
Hartmann G. and Krieg A. M. (2000): Mechanism and function of a newly identified CpG DNA motif in human primary B cells. J. Immunol., 164, 944-953.
-
(2000)
J. Immunol
, vol.164
, pp. 944-953
-
-
Hartmann, G.1
Krieg, A.M.2
-
42
-
-
0141705297
-
Toll-like receptors stimulate human neutrophil function
-
Hayashi F., Means T. K. and Luster A. D. (2003): Toll-like receptors stimulate human neutrophil function. Blood, 102, 2660-2669.
-
(2003)
Blood
, vol.102
, pp. 2660-2669
-
-
Hayashi, F.1
Means, T.K.2
Luster, A.D.3
-
43
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H., Takeuchi O., Kawai T., Kaisho T., Sato S., Sanjo H., Matsumoto M., Hoshino K., Wagner H., Takeda K. and Akira S. (2000): A Toll-like receptor recognizes bacterial DNA. Nature, 408, 740-745.
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
Sanjo, H.6
Matsumoto, M.7
Hoshino, K.8
Wagner, H.9
Takeda, K.10
Akira, S.11
-
44
-
-
28544449710
-
Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction
-
Hessel E. M., Chu M., Lizcano J. O., Chang B., Herman N., Kell S. A., Wills-Karp M. and Coffman R. L. (2005): Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction. J. Exp. Med., 202, 1563-1573.
-
(2005)
J. Exp. Med
, vol.202
, pp. 1563-1573
-
-
Hessel, E.M.1
Chu, M.2
Lizcano, J.O.3
Chang, B.4
Herman, N.5
Kell, S.A.6
Wills-Karp, M.7
Coffman, R.L.8
-
45
-
-
39249084649
-
TLR9 activation induces normal neutrophil responses in a child with IRAK-4 deficiency: Involvement of the direct PI3K pathway
-
Hoarau C., Gerard B., Lescanne E., Henry D., Francois S., Lacapere J. J., El Benna J., Dang P. M., Grandchamp B., Lebranchu Y., Gougerot-Pocidalo M. A. and Elbim C. (2007): TLR9 activation induces normal neutrophil responses in a child with IRAK-4 deficiency: involvement of the direct PI3K pathway. J. Immunol., 179, 4754-4765.
-
(2007)
J. Immunol
, vol.179
, pp. 4754-4765
-
-
Hoarau, C.1
Gerard, B.2
Lescanne, E.3
Henry, D.4
Francois, S.5
Lacapere, J.J.6
El Benna, J.7
Dang, P.M.8
Grandchamp, B.9
Lebranchu, Y.10
Gougerot-Pocidalo, M.A.11
Elbim, C.12
-
46
-
-
33644674834
-
Silencing Toll-like receptor-9 in Pseudomonas aeruginosa keratitis
-
Huang X., Barrett R. P., McClellan S. A. and Hazlett L. D. (2005): Silencing Toll-like receptor-9 in Pseudomonas aeruginosa keratitis. Invest. Ophthalmol. Vis. Sci., 46, 4209-4216.
-
(2005)
Invest. Ophthalmol. Vis. Sci
, vol.46
, pp. 4209-4216
-
-
Huang, X.1
Barrett, R.P.2
McClellan, S.A.3
Hazlett, L.D.4
-
47
-
-
33749490571
-
Innate immune recognition of, and regulation by, DNA
-
Ishii K. J. and Akira S. (2006): Innate immune recognition of, and regulation by, DNA. Trends Immunol., 27, 525-532.
-
(2006)
Trends Immunol
, vol.27
, pp. 525-532
-
-
Ishii, K.J.1
Akira, S.2
-
48
-
-
29244471275
-
A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA
-
Ishii K. J. Coban C., Kato H., Takahashi K., Torii Y., Takeshita F., Ludwig H., Sutter G., Suzuki K., Hemmi H., Sato S., Yamamoto M., Uematzu S., Takeuchi O. and Akira S. (2006): A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA. Nat. Immunol., 7, 40-48.
-
(2006)
Nat. Immunol
, vol.7
, pp. 40-48
-
-
Ishii, K.J.1
Coban, C.2
Kato, H.3
Takahashi, K.4
Torii, Y.5
Takeshita, F.6
Ludwig, H.7
Sutter, G.8
Suzuki, K.9
Hemmi, H.10
Sato, S.11
Yamamoto, M.12
Uematzu, S.13
Takeuchi, O.14
Akira, S.15
-
49
-
-
0023808695
-
Selective synthesis of mRNA and proteins by human peripheral blood neutrophils
-
Jack R. M. and Fearon D. T. (1988): Selective synthesis of mRNA and proteins by human peripheral blood neutrophils. J. Immunol., 140, 4286-4293.
-
(1988)
J. Immunol
, vol.140
, pp. 4286-4293
-
-
Jack, R.M.1
Fearon, D.T.2
-
51
-
-
13944271838
-
Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation
-
Johnson A. C., Heinzel F. P., Diaconu E., Sun Y., Hise A. G., Golenbock D., Lass J. H. and Perlman E. (2005): Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation. Invest. Ophthalmol. Vis. Sci., 46, 589-595.
-
(2005)
Invest. Ophthalmol. Vis. Sci
, vol.46
, pp. 589-595
-
-
Johnson, A.C.1
Heinzel, F.P.2
Diaconu, E.3
Sun, Y.4
Hise, A.G.5
Golenbock, D.6
Lass, J.H.7
Perlman, E.8
-
52
-
-
30744437150
-
Activation of TLR-9 induces IL-8 secretion through peroxynitrite signaling in human neutrophils
-
József L., Khreiss T., El Kebir D. and Filep J. G. (2006): Activation of TLR-9 induces IL-8 secretion through peroxynitrite signaling in human neutrophils. J. Immunol., 176, 1195-1202.
-
(2006)
J. Immunol
, vol.176
, pp. 1195-1202
-
-
József, L.1
Khreiss, T.2
El Kebir, D.3
Filep, J.G.4
-
53
-
-
9444260363
-
CpG motifs in bacterial DNA delay apoptosis of neutrophil granulocytes
-
József L., Khreiss T. and Filep J. G. (2004): CpG motifs in bacterial DNA delay apoptosis of neutrophil granulocytes. FASEB J., 18, 1776-1778.
-
(2004)
FASEB J
, vol.18
, pp. 1776-1778
-
-
József, L.1
Khreiss, T.2
Filep, J.G.3
-
54
-
-
0036771772
-
Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit peroxynitrite formation, NF-κB and AP-1 activation, and IL-8 gene expression in human leukocytes
-
József L., Zouki C., Petasis N. A., Serhan C. N. and Filep J. G. (2002): Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit peroxynitrite formation, NF-κB and AP-1 activation, and IL-8 gene expression in human leukocytes. Proc. Natl. Acad. Sci. USA, 99, 13266-13271.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13266-13271
-
-
József, L.1
Zouki, C.2
Petasis, N.A.3
Serhan, C.N.4
Filep, J.G.5
-
55
-
-
14644403009
-
Toll-like receptor 9-induced type I IFN protects mice from experimental colitis
-
Katakura K., Lee J., Rachmilewitz D., Li G., Eckmann L. and Raz E. (2005): Toll-like receptor 9-induced type I IFN protects mice from experimental colitis. J. Clin. Invest., 115, 695-702.
-
(2005)
J. Clin. Invest
, vol.115
, pp. 695-702
-
-
Katakura, K.1
Lee, J.2
Rachmilewitz, D.3
Li, G.4
Eckmann, L.5
Raz, E.6
-
56
-
-
0030736624
-
Interleukin-10 counterregulates proinflammatory cytokine-induced inhibition of neutrophil apoptosis during sepsis
-
Keel M., Ungethum U. Steckholzer U., Niederer E., Hartung T., Trentz O. and Ertel W. (1997): Interleukin-10 counterregulates proinflammatory cytokine-induced inhibition of neutrophil apoptosis during sepsis. Blood, 90, 3356-3363.
-
(1997)
Blood
, vol.90
, pp. 3356-3363
-
-
Keel, M.1
Ungethum, U.2
Steckholzer, U.3
Niederer, E.4
Hartung, T.5
Trentz, O.6
Ertel, W.7
-
57
-
-
0037174929
-
Loss of pentameric symmetry of C-reactive protein is associated with delayed apoptosis of human neutrophils
-
Khreiss T, József L., Hossain S., Potempa L. A. and Filep J. G. (2002): Loss of pentameric symmetry of C-reactive protein is associated with delayed apoptosis of human neutrophils. J. Biol. Chem., 277, 40775-40781.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 40775-40781
-
-
Khreiss, T.1
József, L.2
Hossain, S.3
Potempa, L.A.4
Filep, J.G.5
-
58
-
-
0036219195
-
CpG motifs in bacterial DNA and their immune effects
-
Krieg A. M. (2002): CpG motifs in bacterial DNA and their immune effects. Annu. Rev. Immunol., 20, 709-760.
-
(2002)
Annu. Rev. Immunol
, vol.20
, pp. 709-760
-
-
Krieg, A.M.1
-
59
-
-
0038717560
-
CpG motifs: The active ingredient in bacterial extracts?
-
Krieg A. M. (2003): CpG motifs: the active ingredient in bacterial extracts? Nat. Med., 9, 831-835.
-
(2003)
Nat. Med
, vol.9
, pp. 831-835
-
-
Krieg, A.M.1
-
60
-
-
33745946911
-
Therapeutic potential of Toll-like receptor 9 activation
-
Krieg A. M. (2006): Therapeutic potential of Toll-like receptor 9 activation. Nat. Rev. Drug Discov., 5, 471-484.
-
(2006)
Nat. Rev. Drug Discov
, vol.5
, pp. 471-484
-
-
Krieg, A.M.1
-
61
-
-
0028931102
-
CpG motifs in bacterial DNA trigger direct B-cell activation
-
Krieg A. M., Yi A. K., Matson S., Waldschmidt T. J., Bishop G. A., Teasdale R., Koretzky G. A. and Klinman D. M. (1995): CpG motifs in bacterial DNA trigger direct B-cell activation. Nature, 374, 546-549.
-
(1995)
Nature
, vol.374
, pp. 546-549
-
-
Krieg, A.M.1
Yi, A.K.2
Matson, S.3
Waldschmidt, T.J.4
Bishop, G.A.5
Teasdale, R.6
Koretzky, G.A.7
Klinman, D.M.8
-
62
-
-
0033975855
-
Cutting edge: Heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells
-
Kol A., Lichtman A. H., Finberg R. W., Libby P. and Kurt-Jones E. A. (2000): Cutting edge: heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells. J. Immunol., 164, 13-17.
-
(2000)
J. Immunol
, vol.164
, pp. 13-17
-
-
Kol, A.1
Lichtman, A.H.2
Finberg, R.W.3
Libby, P.4
Kurt-Jones, E.A.5
-
63
-
-
0030916669
-
The proto-oncogene Bcl-2 and its role in regulating apoptosis
-
Kroemer G. (1997): The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat. Med., 3, 614-620.
-
(1997)
Nat. Med
, vol.3
, pp. 614-620
-
-
Kroemer, G.1
-
64
-
-
0036720456
-
Role of toll-like receptor 2 (TLR2) in neutrophil activation: GM-CSF enhances TLR2 expression and TLR2-mediated interleukin 8 responses in neutrophils
-
Kurt-Jones E. A., Mandell L., Whitney C., Padgett A., Gosselin K., Newburger P. E. and Finberg R. W. (2002): Role of toll-like receptor 2 (TLR2) in neutrophil activation: GM-CSF enhances TLR2 expression and TLR2-mediated interleukin 8 responses in neutrophils. Blood, 100, 1860-1868.
-
(2002)
Blood
, vol.100
, pp. 1860-1868
-
-
Kurt-Jones, E.A.1
Mandell, L.2
Whitney, C.3
Padgett, A.4
Gosselin, K.5
Newburger, P.E.6
Finberg, R.W.7
-
65
-
-
10744219675
-
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
-
Latz E., Schoenemeyer A., Visintin A., Fitzgerald K. A., Monks B. G., Knetter C. F., Lien E., Nilsen N. J., Espevik T. and Golenbock D. T. (2004): TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat. Immunol., 5, 190-198.
-
(2004)
Nat. Immunol
, vol.5
, pp. 190-198
-
-
Latz, E.1
Schoenemeyer, A.2
Visintin, A.3
Fitzgerald, K.A.4
Monks, B.G.5
Knetter, C.F.6
Lien, E.7
Nilsen, N.J.8
Espevik, T.9
Golenbock, D.T.10
-
66
-
-
0027484754
-
Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators
-
Lee A., Whyte M. K. and Haslett C. (1993): Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators. J. Leukoc. Biol., 54, 283-288.
-
(1993)
J. Leukoc. Biol
, vol.54
, pp. 283-288
-
-
Lee, A.1
Whyte, M.K.2
Haslett, C.3
-
67
-
-
13244252211
-
Identification of different bacterial DNAs in human coronary arteries
-
Lehtiniemi J., Karhunen P. J., Goebeler S., Nikkari S. and Nikkari S. T. (2005): Identification of different bacterial DNAs in human coronary arteries. Eur. J. Clin. Invest., 35, 13-16.
-
(2005)
Eur. J. Clin. Invest
, vol.35
, pp. 13-16
-
-
Lehtiniemi, J.1
Karhunen, P.J.2
Goebeler, S.3
Nikkari, S.4
Nikkari, S.T.5
-
68
-
-
33845963384
-
Cytoplasmic targeting motifs control localization of toll-like receptor 9
-
Leifer C. A., Brooks J. C., Hoelzer K., Lopez J., Kennedy M. N., Mazzoni A. and Segal D. M. (2006): Cytoplasmic targeting motifs control localization of toll-like receptor 9. J. Biol. Chem., 281, 35585-35592.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 35585-35592
-
-
Leifer, C.A.1
Brooks, J.C.2
Hoelzer, K.3
Lopez, J.4
Kennedy, M.N.5
Mazzoni, A.6
Segal, D.M.7
-
69
-
-
3142697714
-
TLR9 is localized in the endoplasmic reticulum prior to stimulation
-
Leifer C. A., Kennedy M. N., Mazzoni A., Lee C., Krublak M. J. and Segal D. M. (2004): TLR9 is localized in the endoplasmic reticulum prior to stimulation. J. Immunol., 173, 1179-1183.
-
(2004)
J. Immunol
, vol.173
, pp. 1179-1183
-
-
Leifer, C.A.1
Kennedy, M.N.2
Mazzoni, A.3
Lee, C.4
Krublak, M.J.5
Segal, D.M.6
-
70
-
-
34548230927
-
Getting to the site of inflammation: The leukocyte adhesion cascade updated
-
Ley K., Laudanna C., Cybulsky M. I. and Noursargh S. (2007): Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat. Rev. Immunol., 7, 678-689.
-
(2007)
Nat. Rev. Immunol
, vol.7
, pp. 678-689
-
-
Ley, K.1
Laudanna, C.2
Cybulsky, M.I.3
Noursargh, S.4
-
72
-
-
0742306781
-
Functional characterization of mitochondria in neutrophils: A role restricted to apoptosis
-
Maianski N. A., Geissler J., Srinivasula S. M., Alnemri E. S., Roos D. and Kuijpers T. W. (2004): Functional characterization of mitochondria in neutrophils: a role restricted to apoptosis. Cell Death Differ., 11, 143-153.
-
(2004)
Cell Death Differ
, vol.11
, pp. 143-153
-
-
Maianski, N.A.1
Geissler, J.2
Srinivasula, S.M.3
Alnemri, E.S.4
Roos, D.5
Kuijpers, T.W.6
-
73
-
-
0037079734
-
Granulocyte colony-stimulating factor inhibits the mitochondria- dependent activation of caspase-3 in neutrophils
-
Maianski N. A., Mul F. P. J., van Buul J. D., Roos D. and Kuijpers T. W. (2002): Granulocyte colony-stimulating factor inhibits the mitochondria- dependent activation of caspase-3 in neutrophils. Blood, 99, 672-679.
-
(2002)
Blood
, vol.99
, pp. 672-679
-
-
Maianski, N.A.1
Mul, F.P.J.2
van Buul, J.D.3
Roos, D.4
Kuijpers, T.W.5
-
74
-
-
33644889894
-
Intracellular mammalian DNA stimulates myeloid dendritic cells to produce type I interferons predominantly through a Toll-like receptor 9-independent pathway
-
Martin D. A. and Elkon K. B. (2006): Intracellular mammalian DNA stimulates myeloid dendritic cells to produce type I interferons predominantly through a Toll-like receptor 9-independent pathway. Arthritis Rheum., 54, 951-962.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 951-962
-
-
Martin, D.A.1
Elkon, K.B.2
-
75
-
-
0037127223
-
Peroxynitrite is an essential component of cytokines production mechanism in human monocytes through modulation of nuclear factor-κB DNA binding activity
-
Matata B. M. and Galinanes M. (2002): Peroxynitrite is an essential component of cytokines production mechanism in human monocytes through modulation of nuclear factor-κB DNA binding activity. J. Biol. Chem., 277, 2330-2335.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 2330-2335
-
-
Matata, B.M.1
Galinanes, M.2
-
76
-
-
0031464308
-
Neutrophil apoptosis in the acute respiratory distress syndrome
-
Matute-Bello G., Liles W. C., Radella F., Steinberg K. P., Ruzinski J. T., Jonas M., Chi E. Y., Hudson L. D. and Martin T. R. (1997): Neutrophil apoptosis in the acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med., 156, 1969-1977.
-
(1997)
Am. J. Respir. Crit. Care Med
, vol.156
, pp. 1969-1977
-
-
Matute-Bello, G.1
Liles, W.C.2
Radella, F.3
Steinberg, K.P.4
Ruzinski, J.T.5
Jonas, M.6
Chi, E.Y.7
Hudson, L.D.8
Martin, T.R.9
-
77
-
-
3242710174
-
Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E
-
Michelsen K. S., Wong M. H., Shah P. K., Zhang W., Yano J., Doherty T. M., Akira S., Rajavashisth T. B. and Arditi M. (2004): Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E. Proc. Natl. Acad. Sci. USA, 101, 10679-10684.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 10679-10684
-
-
Michelsen, K.S.1
Wong, M.H.2
Shah, P.K.3
Zhang, W.4
Yano, J.5
Doherty, T.M.6
Akira, S.7
Rajavashisth, T.B.8
Arditi, M.9
-
78
-
-
0025601628
-
Cooperative interaction of nuclear factor-κB- and cis-regulatory enhancer binding protein-like factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines
-
Mukaida N., Mahe Y. and Matsushima K. (1990): Cooperative interaction of nuclear factor-κB- and cis-regulatory enhancer binding protein-like factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines. J. Biol. Chem., 265, 21128-21133.
-
(1990)
J. Biol. Chem
, vol.265
, pp. 21128-21133
-
-
Mukaida, N.1
Mahe, Y.2
Matsushima, K.3
-
79
-
-
0028143676
-
Molecular mechanism of interleukin-8 gene expression
-
Mukaida N., Okamoto S., Ishikawa Y. and Matsushima K. (1994): Molecular mechanism of interleukin-8 gene expression. J. Leukoc. Biol., 56, 554-558.
-
(1994)
J. Leukoc. Biol
, vol.56
, pp. 554-558
-
-
Mukaida, N.1
Okamoto, S.2
Ishikawa, Y.3
Matsushima, K.4
-
80
-
-
0141958218
-
Expression and function of Toll-like receptors in eosinophils: Activation by Toll-like receptor 7 ligand
-
Nagase H., Okugawa S., Ota Y., Yamaguchi M., Tomizawa H., Matsushima K., Ohta K., Yamamoto K. and Hirai K. (2003): Expression and function of Toll-like receptors in eosinophils: activation by Toll-like receptor 7 ligand. J. Immunol., 171, 3977-3982.
-
(2003)
J. Immunol
, vol.171
, pp. 3977-3982
-
-
Nagase, H.1
Okugawa, S.2
Ota, Y.3
Yamaguchi, M.4
Tomizawa, H.5
Matsushima, K.6
Ohta, K.7
Yamamoto, K.8
Hirai, K.9
-
81
-
-
0037180812
-
Points of control of inflammation
-
Nathan C. (2002): Points of control of inflammation. Nature, 420, 846-852.
-
(2002)
Nature
, vol.420
, pp. 846-852
-
-
Nathan, C.1
-
82
-
-
0036316394
-
CpG motifs of bacterial DNA exacerbate colitis of dextran sulfate soidum-treated mice
-
Obermeier F., Dunger N., Deml L., Herfarth H., Scholmerich J. and Falk W. (2002): CpG motifs of bacterial DNA exacerbate colitis of dextran sulfate soidum-treated mice. Eur. J. Immunol., 32, 2084-2092.
-
(2002)
Eur. J. Immunol
, vol.32
, pp. 2084-2092
-
-
Obermeier, F.1
Dunger, N.2
Deml, L.3
Herfarth, H.4
Scholmerich, J.5
Falk, W.6
-
83
-
-
27944453599
-
Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation
-
Okabe Y., Kawane K., Akira S., Taniguchi T. and Nagata S. (2005): Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation. J. Exp. Med., 202, 1333-1339.
-
(2005)
J. Exp. Med
, vol.202
, pp. 1333-1339
-
-
Okabe, Y.1
Kawane, K.2
Akira, S.3
Taniguchi, T.4
Nagata, S.5
-
84
-
-
20044379765
-
The expression and roles of Toll-like receptors in the biology of the human neutrophil
-
Parker L. C., Whyte M. K. B., Dower S. K. and Sabroe I. (2005): The expression and roles of Toll-like receptors in the biology of the human neutrophil. J. Leukoc. Biol., 77, 886-892.
-
(2005)
J. Leukoc. Biol
, vol.77
, pp. 886-892
-
-
Parker, L.C.1
Whyte, M.K.B.2
Dower, S.K.3
Sabroe, I.4
-
85
-
-
33846911691
-
Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9
-
Parroche P., Lauw F. N., Goutagny N., Latz E., Monks B. G., Visintin A., Halmen K. A., Lamphier M., Olivier M., Bartholomeu D. C., Gazzinelli R. T. and Golenbock D. T. (2007): Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9. Proc. Natl. Acad. Sci. USA, 104, 1919-1924.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 1919-1924
-
-
Parroche, P.1
Lauw, F.N.2
Goutagny, N.3
Latz, E.4
Monks, B.G.5
Visintin, A.6
Halmen, K.A.7
Lamphier, M.8
Olivier, M.9
Bartholomeu, D.C.10
Gazzinelli, R.T.11
Golenbock, D.T.12
-
86
-
-
0037021446
-
Mechanisms involved in interleukin-15-induced suppression of human neutrophil apoptosis: Role of the anti-apoptotic Mcl-1 protein and several kinases including Janus kinase-2, p38 mitogen-activated protein kinase and extracellular signal-regulated kinases-1/2
-
Pelletier M., Ratthe C. and Girard D. (2002): Mechanisms involved in interleukin-15-induced suppression of human neutrophil apoptosis: role of the anti-apoptotic Mcl-1 protein and several kinases including Janus kinase-2, p38 mitogen-activated protein kinase and extracellular signal-regulated kinases-1/2. FEBS Lett., 532, 164-170.
-
(2002)
FEBS Lett
, vol.532
, pp. 164-170
-
-
Pelletier, M.1
Ratthe, C.2
Girard, D.3
-
87
-
-
10744233159
-
Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis
-
Rachmilewitz D., Katakura K., Karmeli F., Hayashi T., Reinus C., Rudensky B., Akira S., Takeda K., Lee J., Takabayashi K. and Raz E. (2004): Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis. Gastroenterology, 126, 520-528.
-
(2004)
Gastroenterology
, vol.126
, pp. 520-528
-
-
Rachmilewitz, D.1
Katakura, K.2
Karmeli, F.3
Hayashi, T.4
Reinus, C.5
Rudensky, B.6
Akira, S.7
Takeda, K.8
Lee, J.9
Takabayashi, K.10
Raz, E.11
-
88
-
-
1842424642
-
Triggering receptor expressed on myeloid cells-1 in neutrophil inflammatory responses: Differential regulation of activation and survival
-
Radsak M. P., Shalih H. R., Rammensee H. G. and Schild H. (2004): Triggering receptor expressed on myeloid cells-1 in neutrophil inflammatory responses: differential regulation of activation and survival. J. Immunol., 172, 4956-4963.
-
(2004)
J. Immunol
, vol.172
, pp. 4956-4963
-
-
Radsak, M.P.1
Shalih, H.R.2
Rammensee, H.G.3
Schild, H.4
-
89
-
-
33845753436
-
Usefulness of a molecular strategy for the detection of bacterial DNA in patients with severe sepsis undergoing continuous renal replacement therapy
-
Ratanarat R., Cazzavillan S., Ricci Z., Rassu M., Segala C., de Cal M., Cruz D., Corradi V., Manfro S., Roessler E., Levin N. and Ronco C. (2007): Usefulness of a molecular strategy for the detection of bacterial DNA in patients with severe sepsis undergoing continuous renal replacement therapy. Blood Purif., 25, 106-111.
-
(2007)
Blood Purif
, vol.25
, pp. 106-111
-
-
Ratanarat, R.1
Cazzavillan, S.2
Ricci, Z.3
Rassu, M.4
Segala, C.5
de Cal, M.6
Cruz, D.7
Corradi, V.8
Manfro, S.9
Roessler, E.10
Levin, N.11
Ronco, C.12
-
90
-
-
0030979773
-
Double identity for proteins of the Bcl-2 family
-
Reed J. C. (1997): Double identity for proteins of the Bcl-2 family. Nature, 387, 773-776.
-
(1997)
Nature
, vol.387
, pp. 773-776
-
-
Reed, J.C.1
-
91
-
-
33745957572
-
Proapoptotic multidomain Bcl-2/Bax family proteins: Mechanisms, physiological roles and therapeutic opportunities
-
Reed J. C. (2006): Proapoptotic multidomain Bcl-2/Bax family proteins: mechanisms, physiological roles and therapeutic opportunities. Cell Death Differ., 13, 1378-1386.
-
(2006)
Cell Death Differ
, vol.13
, pp. 1378-1386
-
-
Reed, J.C.1
-
92
-
-
24744452821
-
Differences in macrophage activation by bacterial DNA and CpG-containing oligonucleotides
-
Roberts T. L., Dunn J. A., Terry T. D., Jennings M. P., Hume D. A., Sweet M. J. and Stacey K. J. (2005): Differences in macrophage activation by bacterial DNA and CpG-containing oligonucleotides. J. Immunol., 175, 3569-3576.
-
(2005)
J. Immunol
, vol.175
, pp. 3569-3576
-
-
Roberts, T.L.1
Dunn, J.A.2
Terry, T.D.3
Jennings, M.P.4
Hume, D.A.5
Sweet, M.J.6
Stacey, K.J.7
-
93
-
-
1542674589
-
Immunity to fungal infections
-
Romani L. (2004): Immunity to fungal infections. Nat. Rev. Immunol., 4, 1-23.
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 1-23
-
-
Romani, L.1
-
94
-
-
0036136333
-
Immunostimulatory DNA sequences influence the course of adjuvant arthritis
-
Ronaghy A., Prakken B. J., Takabayashi K., Firestein G. S., Boyle D., Zvailfler N. J., Roord S. T., Albani S., Carson D. A. and Raz E. (2002): Immunostimulatory DNA sequences influence the course of adjuvant arthritis. J. Immunol., 168, 51-56.
-
(2002)
J. Immunol
, vol.168
, pp. 51-56
-
-
Ronaghy, A.1
Prakken, B.J.2
Takabayashi, K.3
Firestein, G.S.4
Boyle, D.5
Zvailfler, N.J.6
Roord, S.T.7
Albani, S.8
Carson, D.A.9
Raz, E.10
-
95
-
-
4644330955
-
Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner
-
Rutz M., Metzger ., Gellert T., Luppa P., Lipford G. B., Wagner H. and Bauer S. (2004): Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner. Eur. J. Immunol., 34, 2541-2550.
-
(2004)
Eur. J. Immunol
, vol.34
, pp. 2541-2550
-
-
Rutz, M.1
Metzger2
Gellert, T.3
Luppa, P.4
Lipford, G.B.5
Wagner, H.6
Bauer, S.7
-
96
-
-
3042568807
-
What can we learn from highly purified neutrophils?
-
Sabroe I., Prince L. R., Dower S. K., Walmsley S. R., Chilvers E. R. and Whyte M. K. (2004): What can we learn from highly purified neutrophils? Biochem. Soc. Trans., 32, 468-469.
-
(2004)
Biochem. Soc. Trans
, vol.32
, pp. 468-469
-
-
Sabroe, I.1
Prince, L.R.2
Dower, S.K.3
Walmsley, S.R.4
Chilvers, E.R.5
Whyte, M.K.6
-
97
-
-
0037883695
-
Selective roles for Toll-like receptor (TLR)2 and TLR4 in the regulation of neutrophil activation and life span
-
Sabroe I., Prince L. R., Jones F. C., Horsburgh M. J., Foster S. J., Vogel S. N., Dower S. K. and Whyte M. K. (2003): Selective roles for Toll-like receptor (TLR)2 and TLR4 in the regulation of neutrophil activation and life span. J. Immunol., 170, 5268-5275.
-
(2003)
J. Immunol
, vol.170
, pp. 5268-5275
-
-
Sabroe, I.1
Prince, L.R.2
Jones, F.C.3
Horsburgh, M.J.4
Foster, S.J.5
Vogel, S.N.6
Dower, S.K.7
Whyte, M.K.8
-
98
-
-
0036884424
-
A blast from the past: Clearance of apoptotic cells regulates immune responses
-
Savill J., Dransfield I., Gregory C. and Haslett C. (2002): A blast from the past: clearance of apoptotic cells regulates immune responses. Nat. Rev. Immunol., 2, 965-975.
-
(2002)
Nat. Rev. Immunol
, vol.2
, pp. 965-975
-
-
Savill, J.1
Dransfield, I.2
Gregory, C.3
Haslett, C.4
-
99
-
-
0025164935
-
Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis
-
Savill J., Dransfield I., Hogg N. and Haslett C. (1990): Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis. Nature, 343, 170-173.
-
(1990)
Nature
, vol.343
, pp. 170-173
-
-
Savill, J.1
Dransfield, I.2
Hogg, N.3
Haslett, C.4
-
100
-
-
0024536234
-
Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages
-
Savill J. S., Wyllie A. H., Henson J. E., Walport M. J., Henson P. M. and Haslett J. C. (1989): Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages. J. Clin. Invest., 83, 865-875.
-
(1989)
J. Clin. Invest
, vol.83
, pp. 865-875
-
-
Savill, J.S.1
Wyllie, A.H.2
Henson, J.E.3
Walport, M.J.4
Henson, P.M.5
Haslett, J.C.6
-
102
-
-
0030859292
-
CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract
-
Schwartz D. A., Quinn T. J., Thorne P. S., Sayeed S., Yi A. K. and Krieg A. M. (1997): CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract. J. Clin. Invest., 100, 68-73.
-
(1997)
J. Clin. Invest
, vol.100
, pp. 68-73
-
-
Schwartz, D.A.1
Quinn, T.J.2
Thorne, P.S.3
Sayeed, S.4
Yi, A.K.5
Krieg, A.M.6
-
103
-
-
33846823024
-
Resolution of inflammation: State of the art, definitions and terms
-
Serhan C. N., Brain S. D., Buckley C. D., Gilroy D. W., Haslett C., O'Neill L. A. J., Perretti M., Rossi A. G. and Wallace J. L. (2007): Resolution of inflammation: state of the art, definitions and terms. FASEB J., 21, 325-332.
-
(2007)
FASEB J
, vol.21
, pp. 325-332
-
-
Serhan, C.N.1
Brain, S.D.2
Buckley, C.D.3
Gilroy, D.W.4
Haslett, C.5
O'Neill, L.A.J.6
Perretti, M.7
Rossi, A.G.8
Wallace, J.L.9
-
104
-
-
30044449982
-
Resolution of inflammation: The beginning programs the end
-
Serhan C. N. and Savill J. (2005): Resolution of inflammation: the beginning programs the end. Nat. Immunol., 6, 1199-1205.
-
(2005)
Nat. Immunol
, vol.6
, pp. 1199-1205
-
-
Serhan, C.N.1
Savill, J.2
-
105
-
-
0038171416
-
Neutrophil apoptosis pathways and their modifications in inflammation
-
Simon H. U. (2003): Neutrophil apoptosis pathways and their modifications in inflammation. Immunol. Rev., 193, 101-110.
-
(2003)
Immunol. Rev
, vol.193
, pp. 101-110
-
-
Simon, H.U.1
-
106
-
-
0030897625
-
Bacterial DNA causes septic shock
-
Sparwasser T., Miethke T., Lipford G., Borschert K., Hacker H., Heeg K. and Wagner H. (1997): Bacterial DNA causes septic shock. Nature, 386, 336-337.
-
(1997)
Nature
, vol.386
, pp. 336-337
-
-
Sparwasser, T.1
Miethke, T.2
Lipford, G.3
Borschert, K.4
Hacker, H.5
Heeg, K.6
Wagner, H.7
-
107
-
-
30444450839
-
Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
-
Stetson D. B. and Medzhitov R. (2006): Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity, 24, 93-103.
-
(2006)
Immunity
, vol.24
, pp. 93-103
-
-
Stetson, D.B.1
Medzhitov, R.2
-
108
-
-
31344466165
-
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9
-
Tabeta K., Hoebe K., Janssen E. M., Du X., Georgel P., Crozat K., Mudd S., Mann N., Sovath S., Goode J., Shamel L., Herskovits A. A., Portnoy D. A., Cooke M., Tarantino L. M., Wiltshire T., Steinberg B. E., Grinstein S. and Beutler B. (2006): The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat. Immunol., 7, 156-164.
-
(2006)
Nat. Immunol
, vol.7
, pp. 156-164
-
-
Tabeta, K.1
Hoebe, K.2
Janssen, E.M.3
Du, X.4
Georgel, P.5
Crozat, K.6
Mudd, S.7
Mann, N.8
Sovath, S.9
Goode, J.10
Shamel, L.11
Herskovits, A.A.12
Portnoy, D.A.13
Cooke, M.14
Tarantino, L.M.15
Wiltshire, T.16
Steinberg, B.E.17
Grinstein, S.18
Beutler, B.19
-
109
-
-
34547143110
-
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
-
Takaoka A., Wang Z. C., Choi M. K., Yanai H., Negishi H., Ban T., Lu Y., Miyagashi M., Kodama T., Honda K., Ohba Y. and Taniguchi T. (2007): DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature, 448, 501-505.
-
(2007)
Nature
, vol.448
, pp. 501-505
-
-
Takaoka, A.1
Wang, Z.C.2
Choi, M.K.3
Yanai, H.4
Negishi, H.5
Ban, T.6
Lu, Y.7
Miyagashi, M.8
Kodama, T.9
Honda, K.10
Ohba, Y.11
Taniguchi, T.12
-
110
-
-
0242559046
-
Bacterial DNA activates human neutrophils by a CpG-independent pathway
-
Trevani A. S., Chorny A., Salamone G., Vermeulen M., Gamberale R., Schettini J., Raiden S. and Geffner J. (2003): Bacterial DNA activates human neutrophils by a CpG-independent pathway. Eur. J. Immunol., 33, 3164-3174.
-
(2003)
Eur. J. Immunol
, vol.33
, pp. 3164-3174
-
-
Trevani, A.S.1
Chorny, A.2
Salamone, G.3
Vermeulen, M.4
Gamberale, R.5
Schettini, J.6
Raiden, S.7
Geffner, J.8
-
111
-
-
0033592748
-
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens
-
Underhill D. M., Ozinsky A., Hajjar A. M., Stevens A., Wislon C.D., Bassetti, M. and Aderem A. (1999): The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature, 401, 811-815.
-
(1999)
Nature
, vol.401
, pp. 811-815
-
-
Underhill, D.M.1
Ozinsky, A.2
Hajjar, A.M.3
Stevens, A.4
Wislon, C.D.5
Bassetti, M.6
Aderem, A.7
-
112
-
-
0031048483
-
Identification of the NO synthase isoforms expressed in human neutrophil granulocytes, megakaryocytes and platelets
-
Wallerath T., Gath I., Aulitzky W. E., Pollock J. S., Kleinert H. and Förstermann U. (1997): Identification of the NO synthase isoforms expressed in human neutrophil granulocytes, megakaryocytes and platelets. Thromb. Haemost., 77, 163-167.
-
(1997)
Thromb. Haemost
, vol.77
, pp. 163-167
-
-
Wallerath, T.1
Gath, I.2
Aulitzky, W.E.3
Pollock, J.S.4
Kleinert, H.5
Förstermann, U.6
-
113
-
-
0034668119
-
Increased resistance against acute polymicrobial sepsis in mice challenged with immunostimulatory CpG oligodeoxynucleotides is related to an enhanced innate effector cell response
-
Weighardt H., Feterowski C., Veit M., Rump M., Wagner H. and Holzmann B. (2000): Increased resistance against acute polymicrobial sepsis in mice challenged with immunostimulatory CpG oligodeoxynucleotides is related to an enhanced innate effector cell response. J. Immunol., 165, 4537-4543.
-
(2000)
J. Immunol
, vol.165
, pp. 4537-4543
-
-
Weighardt, H.1
Feterowski, C.2
Veit, M.3
Rump, M.4
Wagner, H.5
Holzmann, B.6
-
114
-
-
0024602827
-
Tissue destruction by neutrophils
-
Weiss S. J. (1989): Tissue destruction by neutrophils. N. Engl. J. Med., 320, 365-375.
-
(1989)
N. Engl. J. Med
, vol.320
, pp. 365-375
-
-
Weiss, S.J.1
-
115
-
-
0031038025
-
Bacterial infection induces nitric oxide synthase in human neutrophils
-
Wheeler M. A., Smith S.D., Garcia-Cardena G., Nathan C. F., Weiss R. M. and Sessa W. C. (1997): Bacterial infection induces nitric oxide synthase in human neutrophils. J. Clin. Invest., 99, 110-116.
-
(1997)
J. Clin. Invest
, vol.99
, pp. 110-116
-
-
Wheeler, M.A.1
Smith, S.D.2
Garcia-Cardena, G.3
Nathan, C.F.4
Weiss, R.M.5
Sessa, W.C.6
-
116
-
-
0027156167
-
Impairment of function in aging neutrophils is associated with apoptosis
-
Whyte M. K., Meagher L. C., Macdermot J. and Haslett J. C. (1993): Impairment of function in aging neutrophils is associated with apoptosis. J. Immunol., 150, 5124-5134.
-
(1993)
J. Immunol
, vol.150
, pp. 5124-5134
-
-
Whyte, M.K.1
Meagher, L.C.2
Macdermot, J.3
Haslett, J.C.4
-
117
-
-
34547771610
-
Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk
-
Wu H.-J., Sawaya H., Binstadt B., Brickelmaier M., Blasius A., Gorelik L., Mahmood U., Weissleder R., Carulli J., Benoist C. and Mathis D. (2007): Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk. J. Exp. Med., 204, 1911-1922.
-
(2007)
J. Exp. Med
, vol.204
, pp. 1911-1922
-
-
Wu, H.-J.1
Sawaya, H.2
Binstadt, B.3
Brickelmaier, M.4
Blasius, A.5
Gorelik, L.6
Mahmood, U.7
Weissleder, R.8
Carulli, J.9
Benoist, C.10
Mathis, D.11
-
118
-
-
33748957516
-
Intact TRL 9 and type I interferon signaling pathways are required to augment HSV-1 induced corneal CXCL9 and CXCL10
-
Wuest T., Austin B. A., Uematsu S., Thapa M., Akira S. and Carr D. J.(2006): Intact TRL 9 and type I interferon signaling pathways are required to augment HSV-1 induced corneal CXCL9 and CXCL10. J. Neuroimmunol., 179, 46-52.
-
(2006)
J. Neuroimmunol
, vol.179
, pp. 46-52
-
-
Wuest, T.1
Austin, B.A.2
Uematsu, S.3
Thapa, M.4
Akira, S.5
Carr, D.J.6
-
119
-
-
0035910010
-
Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL
-
Xu X. H., Shah P. K., Faure E., Equils O., Thomas L., Fishbein M. C., Luthringer D., Xu X. P., Rajavashisth T. B., Yano J., Kaul S. and Arditi M. (2001): Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL. Circulation, 104, 3103-3108
-
(2001)
Circulation
, vol.104
, pp. 3103-3108
-
-
Xu, X.H.1
Shah, P.K.2
Faure, E.3
Equils, O.4
Thomas, L.5
Fishbein, M.C.6
Luthringer, D.7
Xu, X.P.8
Rajavashisth, T.B.9
Yano, J.10
Kaul, S.11
Arditi, M.12
-
120
-
-
14644387513
-
Macrophage activation by a DNA/cationic liposome complex requires endosomal acidification and TLR9-dependent and -independent pathways
-
Yasuda K. Ogawa Y., Yamane I., Mishikawa M. and Takakura Y. (2005): Macrophage activation by a DNA/cationic liposome complex requires endosomal acidification and TLR9-dependent and -independent pathways. J. Leukoc. Biol., 77, 71-79.
-
(2005)
J. Leukoc. Biol
, vol.77
, pp. 71-79
-
-
Yasuda, K.1
Ogawa, Y.2
Yamane, I.3
Mishikawa, M.4
Takakura, Y.5
-
121
-
-
18644383289
-
Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and -independent pathways
-
Yasuda K., Yu P., Kirschning C. J., Schlatter D., Schmitz F., Heit A., Bauer S., Hochrein H. and Wagner H. (2005): Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and -independent pathways. J. Immunol., 174, 6129-6136.
-
(2005)
J. Immunol
, vol.174
, pp. 6129-6136
-
-
Yasuda, K.1
Yu, P.2
Kirschning, C.J.3
Schlatter, D.4
Schmitz, F.5
Heit, A.6
Bauer, S.7
Hochrein, H.8
Wagner, H.9
-
122
-
-
0032525023
-
CpG motifs in bacterial DNA activate leukocytes through the pH-dependent generation of reactive oxygen species
-
Yi A. K., Tuetken R., Redford T., Waldschmidt M., Kirsch J. and Krieg A. M. (1998): CpG motifs in bacterial DNA activate leukocytes through the pH-dependent generation of reactive oxygen species. J. Immunol., 160, 4755-4761.
-
(1998)
J. Immunol
, vol.160
, pp. 4755-4761
-
-
Yi, A.K.1
Tuetken, R.2
Redford, T.3
Waldschmidt, M.4
Kirsch, J.5
Krieg, A.M.6
-
123
-
-
33744954681
-
CpG DNA-mediated induction of acute liver injury in D-galactosamine-sensitized mice: The mitochondrial apoptotic pathway-dependent death of hepatocytes
-
Yi A. K., Yoon H., Park J. E., Kim B. S., Kim H. J. and Martinez-Hernandez A. (2006): CpG DNA-mediated induction of acute liver injury in D-galactosamine-sensitized mice: the mitochondrial apoptotic pathway-dependent death of hepatocytes. J. Biol. Chem., 281, 15001-15012.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 15001-15012
-
-
Yi, A.K.1
Yoon, H.2
Park, J.E.3
Kim, B.S.4
Kim, H.J.5
Martinez-Hernandez, A.6
-
124
-
-
0025925091
-
+-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells
-
+-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells. J. Biol. Chem., 266, 17707-17712.
-
(1991)
J. Biol. Chem
, vol.266
, pp. 17707-17712
-
-
Yoshimori, T.1
Yamamoto, A.2
Morijama, Y.3
Futai, M.4
Tashiro, Y.5
-
125
-
-
0028903933
-
Reduction of mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo
-
Zamzami N., Marchetti P., Castedo M., Zanin C., Vayssiere J. L., Petit P. X. and Kroemer G. (1995): Reduction of mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J. Exp. Med., 181, 1661-1672.
-
(1995)
J. Exp. Med
, vol.181
, pp. 1661-1672
-
-
Zamzami, N.1
Marchetti, P.2
Castedo, M.3
Zanin, C.4
Vayssiere, J.L.5
Petit, P.X.6
Kroemer, G.7
-
126
-
-
0343831476
-
Peroxynitrite mediates cytokine-induced IL-8 gene expression and production by human leukocytes
-
Zouki C., József L., Ouellet S., Paquette Y. and Filep J. G. (2001): Peroxynitrite mediates cytokine-induced IL-8 gene expression and production by human leukocytes. J. Leukoc. Biol., 69, 815-824.
-
(2001)
J. Leukoc. Biol
, vol.69
, pp. 815-824
-
-
Zouki, C.1
József, L.2
Ouellet, S.3
Paquette, Y.4
Filep, J.G.5
|