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Volumn 5, Issue 2, 2008, Pages 89-103

Genetic polymorphisms of type-1 and type-2 inflammatory cytokines in ischaemic stroke

Author keywords

Atherosclerosis; Cerebral ischaemia; Cytokines; Genetic variations; Inflammation; Polymorphisms; Stroke

Indexed keywords

CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR;

EID: 43049125478     PISSN: 15672700     EISSN: None     Source Type: Journal    
DOI: 10.2174/156727008784223981     Document Type: Review
Times cited : (3)

References (212)
  • 1
    • 0032429906 scopus 로고    scopus 로고
    • Stroke risk factors and stroke prevention
    • Elkind MS, Sacco RL. Stroke risk factors and stroke prevention. Semin Neurol 1998; 18: 429-40.
    • (1998) Semin Neurol , vol.18 , pp. 429-440
    • Elkind, M.S.1    Sacco, R.L.2
  • 2
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis - an inflammatory disease
    • Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med 1999; 340: 115-26.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 3
    • 0141865574 scopus 로고    scopus 로고
    • Inflammation and infections as risk factors for ischemic stroke
    • Lindsberg PJ, Grau AJ. Inflammation and infections as risk factors for ischemic stroke. Stroke 2003; 34: 2518-32.
    • (2003) Stroke , vol.34 , pp. 2518-2532
    • Lindsberg, P.J.1    Grau, A.J.2
  • 4
    • 0037163149 scopus 로고    scopus 로고
    • Innate and adaptive immunity in the pathogenesis of atherosclerosis
    • Hansson GK, Libby P, Schonbeck U, Yan ZQ. Innate and adaptive immunity in the pathogenesis of atherosclerosis. Circ Res 2002; 91: 281-91.
    • (2002) Circ Res , vol.91 , pp. 281-291
    • Hansson, G.K.1    Libby, P.2    Schonbeck, U.3    Yan, Z.Q.4
  • 5
    • 0035571606 scopus 로고    scopus 로고
    • Immune mechanisms in atherosclerosis
    • Hansson GK. Immune mechanisms in atherosclerosis. Arterioscler Thromb Vasc Biol 2001; 21: 1876-90.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1876-1890
    • Hansson, G.K.1
  • 6
    • 0024425754 scopus 로고
    • Atherosclerotic lesions in humans. In situ immunophenotypic analysis suggesting an immune mediated response
    • van der Wal AC, Das PK, Bentz van de Berg D, van der Loos CM, Becker AE. Atherosclerotic lesions in humans. In situ immunophenotypic analysis suggesting an immune mediated response. Lab Invest 1989; 61: 166-70.
    • (1989) Lab Invest , vol.61 , pp. 166-170
    • van der Wal, A.C.1    Das, P.K.2    Bentz van de Berg, D.3    van der Loos, C.M.4    Becker, A.E.5
  • 7
    • 0029053557 scopus 로고
    • T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein
    • Stemme S, Faber B, Holm J, et al. T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein. Proc Natl Acad Sci USA 1995; 92: 3893-7.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3893-3897
    • Stemme, S.1    Faber, B.2    Holm, J.3
  • 8
    • 0034494720 scopus 로고    scopus 로고
    • The Th1-Th2 classification of cellular immune responses: Concepts, current thinking and applications in haematological malignancy
    • Lappin MB, Campbell JD. The Th1-Th2 classification of cellular immune responses: concepts, current thinking and applications in haematological malignancy. Blood Rev 2000; 14: 228-39.
    • (2000) Blood Rev , vol.14 , pp. 228-239
    • Lappin, M.B.1    Campbell, J.D.2
  • 9
    • 0033490502 scopus 로고    scopus 로고
    • Interleukin-12: A cytokine at the interface of inflammation and immunity
    • Trinchieri G. Interleukin-12: a cytokine at the interface of inflammation and immunity. Adv Immunol 1998; 70: 83-243.
    • (1998) Adv Immunol , vol.70 , pp. 83-243
    • Trinchieri, G.1
  • 10
    • 0028288179 scopus 로고
    • Lymphokine production by human T cells in disease states
    • Romagnani S. Lymphokine production by human T cells in disease states. Annu Rev Immunol 1994; 12: 227-57.
    • (1994) Annu Rev Immunol , vol.12 , pp. 227-257
    • Romagnani, S.1
  • 11
    • 0035841265 scopus 로고    scopus 로고
    • Reciprocal induction of IL-10 and IL-12 from macrophages by low-density lipoprotein and its oxidized forms
    • Varadhachary AS, Monestier M, Salgame P. Reciprocal induction of IL-10 and IL-12 from macrophages by low-density lipoprotein and its oxidized forms. Cell Immunol 2001; 213: 45-51.
    • (2001) Cell Immunol , vol.213 , pp. 45-51
    • Varadhachary, A.S.1    Monestier, M.2    Salgame, P.3
  • 12
    • 15844415074 scopus 로고    scopus 로고
    • Cross-regulatory roles of interleukin (IL)-12 and IL-10 in atherosclerosis
    • Uyemura K, Demer LL, Castle SC, et al. Cross-regulatory roles of interleukin (IL)-12 and IL-10 in atherosclerosis. J Clin Invest 1996; 97: 2130-8.
    • (1996) J Clin Invest , vol.97 , pp. 2130-2138
    • Uyemura, K.1    Demer, L.L.2    Castle, S.C.3
  • 13
    • 0031569126 scopus 로고    scopus 로고
    • Roles of IL-4 and IFN-gamma in stabilizing the T helper cell type 1 and 2 phenotype
    • Nakamura T, Lee RK, Nam SY, et al. Roles of IL-4 and IFN-gamma in stabilizing the T helper cell type 1 and 2 phenotype. J Immunol 1997; 158: 2648-53.
    • (1997) J Immunol , vol.158 , pp. 2648-2653
    • Nakamura, T.1    Lee, R.K.2    Nam, S.Y.3
  • 14
    • 0026648380 scopus 로고
    • Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system
    • Hsieh CS, Heimberger AB, Gold JS, O'Garra A, Murphy KM. Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system. Proc Natl Acad Sci USA 1992; 89: 6065-9.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6065-6069
    • Hsieh, C.S.1    Heimberger, A.B.2    Gold, J.S.3    O'Garra, A.4    Murphy, K.M.5
  • 15
    • 0027240219 scopus 로고
    • Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells
    • D'Andrea A, Aste-Amezaga M, Valiante NM, et al. Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells. J Exp Med 1993; 178: 1041-8.
    • (1993) J Exp Med , vol.178 , pp. 1041-1048
    • D'Andrea, A.1    Aste-Amezaga, M.2    Valiante, N.M.3
  • 16
    • 0033048632 scopus 로고    scopus 로고
    • Cytokine expression in advanced human atherosclerotic plaques: Dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines
    • Frostegard J, Ulfgren AK, Nyberg P, et al. Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines. Atherosclerosis 1999; 145: 33-43.
    • (1999) Atherosclerosis , vol.145 , pp. 33-43
    • Frostegard, J.1    Ulfgren, A.K.2    Nyberg, P.3
  • 17
    • 0024818401 scopus 로고
    • Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes
    • Osborn L, Hession C, Tizard R, et al. Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes. Cell 1989; 59: 1203-11.
    • (1989) Cell , vol.59 , pp. 1203-1211
    • Osborn, L.1    Hession, C.2    Tizard, R.3
  • 18
    • 0027996407 scopus 로고
    • Intercellular adhesion molecule-1 (ICAM-1) expression and soluble ICAM-1 (sICAM-1) production by cytokine-activated human aortic endothelial cells: A possible role for ICAM-1 and sICAM-1 in atherosclerotic aortic aneurysms
    • Szekanecz Z, Shah MR, Pearce WH, Koch AE. Intercellular adhesion molecule-1 (ICAM-1) expression and soluble ICAM-1 (sICAM-1) production by cytokine-activated human aortic endothelial cells: a possible role for ICAM-1 and sICAM-1 in atherosclerotic aortic aneurysms. Clin Exp Immunol 1994; 98: 337-43.
    • (1994) Clin Exp Immunol , vol.98 , pp. 337-343
    • Szekanecz, Z.1    Shah, M.R.2    Pearce, W.H.3    Koch, A.E.4
  • 19
    • 0026657616 scopus 로고
    • Effects of tumor necrosis factor, lipopolysaccharide, and IL-4 on the expression of vascular cell adhesion molecule-1 in vivo. Correlation with CD3+ T cell infiltration
    • Briscoe DM, Cotran RS, Pober JS. Effects of tumor necrosis factor, lipopolysaccharide, and IL-4 on the expression of vascular cell adhesion molecule-1 in vivo. Correlation with CD3+ T cell infiltration. J Immunol 1992; 149: 2954-60.
    • (1992) J Immunol , vol.149 , pp. 2954-2960
    • Briscoe, D.M.1    Cotran, R.S.2    Pober, J.S.3
  • 20
    • 0031692942 scopus 로고    scopus 로고
    • IL-10 inhibits ICAM-1 expression on human Langerhans cells but not on keratinocytes, dermal endothelial cells or fibroblasts
    • Chatelain R, Wollenberg A, Martin C, et al. IL-10 inhibits ICAM-1 expression on human Langerhans cells but not on keratinocytes, dermal endothelial cells or fibroblasts. Arch Dermatol Res 1998; 290: 477-82.
    • (1998) Arch Dermatol Res , vol.290 , pp. 477-482
    • Chatelain, R.1    Wollenberg, A.2    Martin, C.3
  • 21
    • 0026469087 scopus 로고
    • Human arterial smooth muscle cells synthesize granulocyte colony-stimulating factor in response to interleukin-1 alpha and tumor necrosis factor-alpha
    • Zoellner H, Filonzi EL, Stanton HR, Layton JE, Hamilton JA. Human arterial smooth muscle cells synthesize granulocyte colony-stimulating factor in response to interleukin-1 alpha and tumor necrosis factor-alpha. Blood 1992; 80: 2805-10.
    • (1992) Blood , vol.80 , pp. 2805-2810
    • Zoellner, H.1    Filonzi, E.L.2    Stanton, H.R.3    Layton, J.E.4    Hamilton, J.A.5
  • 22
    • 0027223538 scopus 로고
    • Cytokine regulation of granulocyte-macrophage colony stimulating factor and macrophage colony-stimulating factor production in human arterial smooth muscle cells
    • Filonzi EL, Zoellner H, Stanton H, Hamilton JA. Cytokine regulation of granulocyte-macrophage colony stimulating factor and macrophage colony-stimulating factor production in human arterial smooth muscle cells. Atherosclerosis 1993; 99: 241-52.
    • (1993) Atherosclerosis , vol.99 , pp. 241-252
    • Filonzi, E.L.1    Zoellner, H.2    Stanton, H.3    Hamilton, J.A.4
  • 23
    • 0024811224 scopus 로고
    • Interferon gamma inhibits both proliferation and expression of differentiation-specific alpha-smooth muscle actin in arterial smooth muscle cells
    • Hansson GK, Hellstrand M, Rymo L, Rubbia L, Gabbiani G. Interferon gamma inhibits both proliferation and expression of differentiation-specific alpha-smooth muscle actin in arterial smooth muscle cells. J Exp Med 1989; 170: 1595-608.
    • (1989) J Exp Med , vol.170 , pp. 1595-1608
    • Hansson, G.K.1    Hellstrand, M.2    Rymo, L.3    Rubbia, L.4    Gabbiani, G.5
  • 24
    • 0025800329 scopus 로고
    • Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells
    • Amento EP, Ehsani N, Palmer H, Libby P. Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells. Arterioscler Thromb 1991; 11: 1223-30.
    • (1991) Arterioscler Thromb , vol.11 , pp. 1223-1230
    • Amento, E.P.1    Ehsani, N.2    Palmer, H.3    Libby, P.4
  • 25
    • 0028944471 scopus 로고
    • Enhanced expression of vascular matrix metalloproteinases induced in vitro by cytokines and in regions of human atherosclerotic lesions
    • Galis ZS, Muszynski M, Sukhova GK, Simon-Morrissey E, Libby P. Enhanced expression of vascular matrix metalloproteinases induced in vitro by cytokines and in regions of human atherosclerotic lesions. Ann N Y Acad Sci 1995; 748: 501-7.
    • (1995) Ann N Y Acad Sci , vol.748 , pp. 501-507
    • Galis, Z.S.1    Muszynski, M.2    Sukhova, G.K.3    Simon-Morrissey, E.4    Libby, P.5
  • 26
    • 0343742520 scopus 로고    scopus 로고
    • Activation of monocyte/macrophage functions related to acute atheroma complication by ligation of CD40: Induction of collagenase, stromelysin, and tissue factor
    • Mach F, Schonbeck U, Bonnefoy JY, Pober JS, Libby P. Activation of monocyte/macrophage functions related to acute atheroma complication by ligation of CD40: induction of collagenase, stromelysin, and tissue factor. Circulation 1997; 96: 396-9.
    • (1997) Circulation , vol.96 , pp. 396-399
    • Mach, F.1    Schonbeck, U.2    Bonnefoy, J.Y.3    Pober, J.S.4    Libby, P.5
  • 27
    • 0030295230 scopus 로고    scopus 로고
    • Inhibition of IL-1 induced tissue factor (TF) synthesis and procoagulant activity (PCA) in purified human monocytes by IL-4, IL-10 and IL-13
    • Osnes LT, Westvik AB, Joo GB, Okkenhaug C, Kierulf P. Inhibition of IL-1 induced tissue factor (TF) synthesis and procoagulant activity (PCA) in purified human monocytes by IL-4, IL-10 and IL-13. Cytokine 1996; 8: 822-7.
    • (1996) Cytokine , vol.8 , pp. 822-827
    • Osnes, L.T.1    Westvik, A.B.2    Joo, G.B.3    Okkenhaug, C.4    Kierulf, P.5
  • 28
    • 0026657002 scopus 로고
    • IL-4 inhibits LPS-, IL-1 beta- and TNF alpha-induced expression of tissue factor in endothelial cells and monocytes
    • Herbert JM, Savi P, Laplace MC, Lale A. IL-4 inhibits LPS-, IL-1 beta- and TNF alpha-induced expression of tissue factor in endothelial cells and monocytes. FEBS Lett 1992; 310: 31-3.
    • (1992) FEBS Lett , vol.310 , pp. 31-33
    • Herbert, J.M.1    Savi, P.2    Laplace, M.C.3    Lale, A.4
  • 29
    • 0036796223 scopus 로고    scopus 로고
    • Cytokines in the pathogenesis of atherosclerosis
    • Young JL, Libby P, Schonbeck U. Cytokines in the pathogenesis of atherosclerosis. Thromb Haemost 2002; 88: 554-67.
    • (2002) Thromb Haemost , vol.88 , pp. 554-567
    • Young, J.L.1    Libby, P.2    Schonbeck, U.3
  • 30
    • 0030974188 scopus 로고    scopus 로고
    • IFN-gamma potentiates atherosclerosis in ApoE knock-out mice
    • Gupta S, Pablo AM, Jiang X, et al. IFN-gamma potentiates atherosclerosis in ApoE knock-out mice. J Clin Invest 1997; 99: 2752-61.
    • (1997) J Clin Invest , vol.99 , pp. 2752-2761
    • Gupta, S.1    Pablo, A.M.2    Jiang, X.3
  • 31
    • 0042926424 scopus 로고    scopus 로고
    • The role of interleukin-4 and interleukin-12 in the progression of atherosclerosis in apolipoprotein Edeficient mice
    • Davenport P, Tipping PG. The role of interleukin-4 and interleukin-12 in the progression of atherosclerosis in apolipoprotein Edeficient mice. Am J Pathol 2003; 163: 1117-25.
    • (2003) Am J Pathol , vol.163 , pp. 1117-1125
    • Davenport, P.1    Tipping, P.G.2
  • 32
    • 0035838424 scopus 로고    scopus 로고
    • In vivo downregulation of T helper cell 1 immune responses reduces atherogenesis in apolipoprotein E-knockout mice
    • Laurat E, Poirier B, Tupin E, et al. In vivo downregulation of T helper cell 1 immune responses reduces atherogenesis in apolipoprotein E-knockout mice. Circulation 2001; 104: 197-202.
    • (2001) Circulation , vol.104 , pp. 197-202
    • Laurat, E.1    Poirier, B.2    Tupin, E.3
  • 33
    • 0037205317 scopus 로고    scopus 로고
    • Overexpression of interleukin-10 by activated T lymphocytes inhibits atherosclerosis in LDL receptor-deficient Mice by altering lymphocyte and macrophage phenotypes
    • Pinderski LJ, Fischbein MP, Subbanagounder G, et al. Overexpression of interleukin-10 by activated T lymphocytes inhibits atherosclerosis in LDL receptor-deficient Mice by altering lymphocyte and macrophage phenotypes. Circ Res 2002; 90: 1064-71.
    • (2002) Circ Res , vol.90 , pp. 1064-1071
    • Pinderski, L.J.1    Fischbein, M.P.2    Subbanagounder, G.3
  • 34
    • 0036035527 scopus 로고    scopus 로고
    • Inflammatory bio-markers and cardiovascular risk prediction
    • Blake GJ, Ridker PM. Inflammatory bio-markers and cardiovascular risk prediction. J Intern Med 2002; 252: 283-94.
    • (2002) J Intern Med , vol.252 , pp. 283-294
    • Blake, G.J.1    Ridker, P.M.2
  • 35
    • 85136409017 scopus 로고    scopus 로고
    • Ridker PM, Stampfer MJ, Rifai N. Novel risk factors for systemic atherosclerosis: a comparison of C-reactive protein, fibrinogen, homocysteine, lipoprotein(a), and standard cholesterol screening as predictors of peripheral arterial disease. JAMA 2001; 285: 2481-5.
    • Ridker PM, Stampfer MJ, Rifai N. Novel risk factors for systemic atherosclerosis: a comparison of C-reactive protein, fibrinogen, homocysteine, lipoprotein(a), and standard cholesterol screening as predictors of peripheral arterial disease. JAMA 2001; 285: 2481-5.
  • 36
    • 0035067998 scopus 로고    scopus 로고
    • C-reactive protein in ischemic stroke: An independent prognostic factor
    • Di Napoli M, Papa F, Bocola V. C-reactive protein in ischemic stroke: an independent prognostic factor. Stroke 2001; 32: 917-24.
    • (2001) Stroke , vol.32 , pp. 917-924
    • Di Napoli, M.1    Papa, F.2    Bocola, V.3
  • 37
    • 0035170373 scopus 로고    scopus 로고
    • Plasma concentration of Creactive protein and risk of ischemic stroke and transient ischemic attack: The Framingham study
    • Rost NS, Wolf PA, Kase CS, et al. Plasma concentration of Creactive protein and risk of ischemic stroke and transient ischemic attack: the Framingham study. Stroke 2001; 32: 2575-9.
    • (2001) Stroke , vol.32 , pp. 2575-2579
    • Rost, N.S.1    Wolf, P.A.2    Kase, C.S.3
  • 38
    • 0242610488 scopus 로고    scopus 로고
    • Inflammatory markers and onset of cardiovascular events: Results from the Health ABC study
    • Cesari M, Penninx BW, Newman AB, et al. Inflammatory markers and onset of cardiovascular events: results from the Health ABC study. Circulation 2003; 108: 2317-22.
    • (2003) Circulation , vol.108 , pp. 2317-2322
    • Cesari, M.1    Penninx, B.W.2    Newman, A.B.3
  • 39
    • 0036218990 scopus 로고    scopus 로고
    • Inflammation and stroke: The Leiden 85-Plus Study
    • van Exel E, Gussekloo J, de Craen AJ, et al. Inflammation and stroke: the Leiden 85-Plus Study. Stroke 2002; 33: 1135-8.
    • (2002) Stroke , vol.33 , pp. 1135-1138
    • van Exel, E.1    Gussekloo, J.2    de Craen, A.J.3
  • 41
    • 0031982968 scopus 로고    scopus 로고
    • Inflammation and acute stroke
    • Becker KJ. Inflammation and acute stroke. Curr Opin Neurol 1998; 11: 45-9.
    • (1998) Curr Opin Neurol , vol.11 , pp. 45-49
    • Becker, K.J.1
  • 42
    • 0031685143 scopus 로고    scopus 로고
    • The role of inflammation after acute stroke: Utility of pursuing anti-adhesion molecule therapy
    • DeGraba TJ. The role of inflammation after acute stroke: utility of pursuing anti-adhesion molecule therapy. Neurology 1998; 51: S62-8.
    • (1998) Neurology , vol.51
    • DeGraba, T.J.1
  • 43
    • 0031759682 scopus 로고    scopus 로고
    • Reperfusion injury after focal cerebral ischemia: The role of inflammation and the therapeutic horizon
    • discussion 1396-7
    • Jean WC, Spellman SR, Nussbaum ES, Low WC. Reperfusion injury after focal cerebral ischemia: the role of inflammation and the therapeutic horizon. Neurosurgery 1998; 43: 1382-96; discussion 1396-7.
    • (1998) Neurosurgery , vol.43 , pp. 1382-1396
    • Jean, W.C.1    Spellman, S.R.2    Nussbaum, E.S.3    Low, W.C.4
  • 44
    • 0036935538 scopus 로고    scopus 로고
    • Detrimental and beneficial effects of injury-induced inflammation and cytokine expression in the nervous system
    • Stoll G, Jander S, Schroeter M. Detrimental and beneficial effects of injury-induced inflammation and cytokine expression in the nervous system. Adv Exp Med Biol 2002; 513: 87-113.
    • (2002) Adv Exp Med Biol , vol.513 , pp. 87-113
    • Stoll, G.1    Jander, S.2    Schroeter, M.3
  • 45
    • 0242566472 scopus 로고    scopus 로고
    • Post-stroke inflammatory response: Effects of stroke evolution and outcome
    • Tan KT, Lip GY, Blann AD. Post-stroke inflammatory response: effects of stroke evolution and outcome. Curr Atheroscler Rep 2003; 5: 245-51.
    • (2003) Curr Atheroscler Rep , vol.5 , pp. 245-251
    • Tan, K.T.1    Lip, G.Y.2    Blann, A.D.3
  • 46
    • 0037312886 scopus 로고    scopus 로고
    • Inflammatory mechanisms after ischemia and stroke
    • Danton GH, Dietrich WD. Inflammatory mechanisms after ischemia and stroke. J Neuropathol Exp Neurol 2003; 62: 127-36.
    • (2003) J Neuropathol Exp Neurol , vol.62 , pp. 127-136
    • Danton, G.H.1    Dietrich, W.D.2
  • 48
    • 1642455873 scopus 로고    scopus 로고
    • Role of inflammation in stroke and atherothrombosis
    • Chamorro A. Role of inflammation in stroke and atherothrombosis. Cerebrovasc Dis 2004; 17 (Suppl 3): 1-5.
    • (2004) Cerebrovasc Dis , vol.17 , Issue.SUPPL. 3 , pp. 1-5
    • Chamorro, A.1
  • 49
    • 12744260011 scopus 로고    scopus 로고
    • The neuroprotective role of inflammation in nervous system injuries
    • Correale J, Villa A. The neuroprotective role of inflammation in nervous system injuries. J Neurol 2004; 251: 1304-16.
    • (2004) J Neurol , vol.251 , pp. 1304-1316
    • Correale, J.1    Villa, A.2
  • 51
    • 0029100108 scopus 로고
    • Circulating selectinand immunoglobulin-type adhesion molecules in acute ischemic stroke
    • Fassbender K, Mossner R, Motsch L, et al. Circulating selectinand immunoglobulin-type adhesion molecules in acute ischemic stroke. Stroke 1995; 26: 1361-4.
    • (1995) Stroke , vol.26 , pp. 1361-1364
    • Fassbender, K.1    Mossner, R.2    Motsch, L.3
  • 52
    • 0031681362 scopus 로고    scopus 로고
    • A longitudinal prospective study of soluble adhesion molecules in acute stroke
    • Bitsch A, Klene W, Murtada L, Prange H, Rieckmann P. A longitudinal prospective study of soluble adhesion molecules in acute stroke. Stroke 1998; 29: 2129-35.
    • (1998) Stroke , vol.29 , pp. 2129-2135
    • Bitsch, A.1    Klene, W.2    Murtada, L.3    Prange, H.4    Rieckmann, P.5
  • 53
    • 0029808409 scopus 로고    scopus 로고
    • Endothelial ICAM-1 expression associated with inflammatory cell response in human ischemic stroke
    • Lindsberg PJ, Carpen O, Paetau A, Karjalainen-Lindsberg ML, Kaste M. Endothelial ICAM-1 expression associated with inflammatory cell response in human ischemic stroke. Circulation 1996; 94: 939-45.
    • (1996) Circulation , vol.94 , pp. 939-945
    • Lindsberg, P.J.1    Carpen, O.2    Paetau, A.3    Karjalainen-Lindsberg, M.L.4    Kaste, M.5
  • 54
    • 0026667919 scopus 로고
    • Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke
    • Kochanek PM, Hallenbeck JM. Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke. Stroke 1992; 23: 1367-79.
    • (1992) Stroke , vol.23 , pp. 1367-1379
    • Kochanek, P.M.1    Hallenbeck, J.M.2
  • 55
    • 0028854369 scopus 로고
    • Lymphocytic infiltration and expression of intercellular adhesion molecule-1 in photochemically induced ischemia of the rat cortex
    • Jander S, Kraemer M, Schroeter M, Witte OW, Stoll G. Lymphocytic infiltration and expression of intercellular adhesion molecule-1 in photochemically induced ischemia of the rat cortex. J Cereb Blood Flow Metab 1995; 15: 42-51.
    • (1995) J Cereb Blood Flow Metab , vol.15 , pp. 42-51
    • Jander, S.1    Kraemer, M.2    Schroeter, M.3    Witte, O.W.4    Stoll, G.5
  • 56
    • 0027497840 scopus 로고
    • Leukocyte infiltration in acute hemispheric ischemic stroke
    • Wang PY, Kao CH, Mui MY, Wang SJ. Leukocyte infiltration in acute hemispheric ischemic stroke. Stroke 1993; 24: 236-40.
    • (1993) Stroke , vol.24 , pp. 236-240
    • Wang, P.Y.1    Kao, C.H.2    Mui, M.Y.3    Wang, S.J.4
  • 57
    • 0029780302 scopus 로고    scopus 로고
    • Dynamics of polymorphonuclear leukocyte accumulation in acute cerebral infarction and their correlation with brain tissue damage
    • Akopov SE, Simonian NA, Grigorian GS. Dynamics of polymorphonuclear leukocyte accumulation in acute cerebral infarction and their correlation with brain tissue damage. Stroke 1996; 27: 1739-43.
    • (1996) Stroke , vol.27 , pp. 1739-1743
    • Akopov, S.E.1    Simonian, N.A.2    Grigorian, G.S.3
  • 58
    • 0032937860 scopus 로고    scopus 로고
    • The role of microglia and macrophages in the pathophysiology of the CNS
    • Stoll G, Jander S. The role of microglia and macrophages in the pathophysiology of the CNS. Prog Neurobiol 1999; 58: 233-47.
    • (1999) Prog Neurobiol , vol.58 , pp. 233-247
    • Stoll, G.1    Jander, S.2
  • 59
    • 0027436533 scopus 로고    scopus 로고
    • Liu T, McDonnell PC, Young PR, et al. Interleukin-1 beta mRNA expression in ischemic rat cortex. Stroke 1993; 24: 1746-50; discussion 1750-1.
    • Liu T, McDonnell PC, Young PR, et al. Interleukin-1 beta mRNA expression in ischemic rat cortex. Stroke 1993; 24: 1746-50; discussion 1750-1.
  • 60
    • 0031470830 scopus 로고    scopus 로고
    • Expression of TNF and TNF receptors (p55 and p75) in the rat brain after focal cerebral ischemia
    • Botchkina GI, Meistrell ME, 3rd, Botchkina IL, Tracey KJ. Expression of TNF and TNF receptors (p55 and p75) in the rat brain after focal cerebral ischemia. Mol Med 1997; 3: 765-81.
    • (1997) Mol Med , vol.3 , pp. 765-781
    • Botchkina, G.I.1    Meistrell 3rd, M.E.2    Botchkina, I.L.3    Tracey, K.J.4
  • 61
    • 0029738548 scopus 로고    scopus 로고
    • Glial expression of cytokines in the brains of cerebrovascular disease patients
    • Tomimoto H, Akiguchi I, Wakita H, et al. Glial expression of cytokines in the brains of cerebrovascular disease patients. Acta Neuropathol (Berl) 1996; 92: 281-7.
    • (1996) Acta Neuropathol (Berl) , vol.92 , pp. 281-287
    • Tomimoto, H.1    Akiguchi, I.2    Wakita, H.3
  • 62
    • 0029132696 scopus 로고
    • Early intrathecal production of interleukin-6 predicts the size of brain lesion in stroke
    • Tarkowski E, Rosengren L, Blomstrand C, et al. Early intrathecal production of interleukin-6 predicts the size of brain lesion in stroke. Stroke 1995; 26: 1393-8.
    • (1995) Stroke , vol.26 , pp. 1393-1398
    • Tarkowski, E.1    Rosengren, L.2    Blomstrand, C.3
  • 63
    • 0036712364 scopus 로고    scopus 로고
    • Induction of mucosal tolerance to E-selectin prevents ischemic and hemorrhagic stroke in spontaneously hypertensive genetically stroke-prone rats
    • Takeda H, Spatz M, Ruetzler C, et al. Induction of mucosal tolerance to E-selectin prevents ischemic and hemorrhagic stroke in spontaneously hypertensive genetically stroke-prone rats. Stroke 2002; 33: 2156-63.
    • (2002) Stroke , vol.33 , pp. 2156-2163
    • Takeda, H.1    Spatz, M.2    Ruetzler, C.3
  • 64
    • 0033587739 scopus 로고    scopus 로고
    • Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury
    • Scherbel U, Raghupathi R, Nakamura M, et al. Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury. Proc Natl Acad Sci U S A 1999; 96: 8721-6.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 8721-8726
    • Scherbel, U.1    Raghupathi, R.2    Nakamura, M.3
  • 65
    • 0034892418 scopus 로고    scopus 로고
    • Evolution of cerebral tumor necrosis factor-alpha production during human ischemic stroke
    • Sairanen T, Carpen O, Karjalainen-Lindsberg ML, et al. Evolution of cerebral tumor necrosis factor-alpha production during human ischemic stroke. Stroke 2001; 32: 1750-8.
    • (2001) Stroke , vol.32 , pp. 1750-1758
    • Sairanen, T.1    Carpen, O.2    Karjalainen-Lindsberg, M.L.3
  • 66
    • 0035705454 scopus 로고    scopus 로고
    • TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination
    • Arnett HA, Mason J, Marino M, et al. TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination. Nat Neurosci 2001; 4: 1116-22.
    • (2001) Nat Neurosci , vol.4 , pp. 1116-1122
    • Arnett, H.A.1    Mason, J.2    Marino, M.3
  • 67
    • 0031780850 scopus 로고    scopus 로고
    • Persistent inflammatory response in stroke survivors
    • Beamer NB, Coull BM, Clark WM, et al. Persistent inflammatory response in stroke survivors. Neurology 1998; 50: 1722-8.
    • (1998) Neurology , vol.50 , pp. 1722-1728
    • Beamer, N.B.1    Coull, B.M.2    Clark, W.M.3
  • 69
    • 4444285836 scopus 로고    scopus 로고
    • Plasma levels of inflammatory C-reactive protein and interleukin-6 predict outcome in elderly patients with stroke
    • Silvestri A, Vitale C, Ferretti F, et al. Plasma levels of inflammatory C-reactive protein and interleukin-6 predict outcome in elderly patients with stroke. J Am Geriatr Soc 2004; 52: 1586-7.
    • (2004) J Am Geriatr Soc , vol.52 , pp. 1586-1587
    • Silvestri, A.1    Vitale, C.2    Ferretti, F.3
  • 70
    • 18944391802 scopus 로고    scopus 로고
    • IL-6: An early marker for outcome in acute ischemic stroke
    • Waje-Andreassen U, Krakenes J, Ulvestad E, et al. IL-6: an early marker for outcome in acute ischemic stroke. Acta Neurol Scand 2005; 111: 360-5.
    • (2005) Acta Neurol Scand , vol.111 , pp. 360-365
    • Waje-Andreassen, U.1    Krakenes, J.2    Ulvestad, E.3
  • 71
    • 0142186347 scopus 로고    scopus 로고
    • Interleukin-18 in acute ischaemic stroke patients
    • Zaremba J, Losy J. Interleukin-18 in acute ischaemic stroke patients. Neurol Sci 2003; 24: 117-24.
    • (2003) Neurol Sci , vol.24 , pp. 117-124
    • Zaremba, J.1    Losy, J.2
  • 72
    • 0035889717 scopus 로고    scopus 로고
    • Monocyte function and plasma levels of interleukin-8 in acute ischemic stroke
    • Grau AJ, Reis A, Buggle F, et al. Monocyte function and plasma levels of interleukin-8 in acute ischemic stroke. J Neurol Sci 2001; 192: 41-7.
    • (2001) J Neurol Sci , vol.192 , pp. 41-47
    • Grau, A.J.1    Reis, A.2    Buggle, F.3
  • 73
    • 0033502965 scopus 로고    scopus 로고
    • Increased cytokine release from peripheral blood cells after acute stroke
    • Ferrarese C, Mascarucci P, Zoia C, et al. Increased cytokine release from peripheral blood cells after acute stroke. J Cereb Blood Flow Metab 1999; 19: 1004-9.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 1004-1009
    • Ferrarese, C.1    Mascarucci, P.2    Zoia, C.3
  • 74
    • 0033795665 scopus 로고    scopus 로고
    • Proinflammatory cytokines and early neurological worsening in ischemic stroke
    • Vila N, Castillo J, Davalos A, Chamorro A. Proinflammatory cytokines and early neurological worsening in ischemic stroke. Stroke 2000; 31: 2325-9.
    • (2000) Stroke , vol.31 , pp. 2325-2329
    • Vila, N.1    Castillo, J.2    Davalos, A.3    Chamorro, A.4
  • 75
    • 0028220499 scopus 로고
    • Proinflammatory cytokines in serum of patients with acute cerebral ischemia: Kinetics of secretion and relation to the extent of brain damage and outcome of disease
    • Fassbender K, Rossol S, Kammer T, et al. Proinflammatory cytokines in serum of patients with acute cerebral ischemia: kinetics of secretion and relation to the extent of brain damage and outcome of disease. J Neurol Sci 1994; 122: 135-9.
    • (1994) J Neurol Sci , vol.122 , pp. 135-139
    • Fassbender, K.1    Rossol, S.2    Kammer, T.3
  • 76
    • 0036214866 scopus 로고    scopus 로고
    • Inflammation-mediated damage in progressing lacunar infarctions: A potential therapeutic target
    • Castellanos M, Castillo J, Garcia MM, et al. Inflammation-mediated damage in progressing lacunar infarctions: a potential therapeutic target. Stroke 2002; 33: 982-7.
    • (2002) Stroke , vol.33 , pp. 982-987
    • Castellanos, M.1    Castillo, J.2    Garcia, M.M.3
  • 77
    • 1342291175 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha serum levels and inflammatory response in acute ischemic stroke patients
    • Intiso D, Zarrelli MM, Lagioia G, et al. Tumor necrosis factor alpha serum levels and inflammatory response in acute ischemic stroke patients. Neurol Sci 2004; 24: 390-6.
    • (2004) Neurol Sci , vol.24 , pp. 390-396
    • Intiso, D.1    Zarrelli, M.M.2    Lagioia, G.3
  • 78
    • 0037335934 scopus 로고    scopus 로고
    • Levels of anti-inflammatory cytokines and neurological worsening in acute ischemic stroke
    • Vila N, Castillo J, Davalos A, et al. Levels of anti-inflammatory cytokines and neurological worsening in acute ischemic stroke. Stroke 2003; 34: 671-5.
    • (2003) Stroke , vol.34 , pp. 671-675
    • Vila, N.1    Castillo, J.2    Davalos, A.3
  • 79
    • 0032779717 scopus 로고    scopus 로고
    • High levels of IL-10 secreting cells are present in blood in cerebrovascular diseases
    • Pelidou SH, Kostulas N, Matusevicius D, et al. High levels of IL-10 secreting cells are present in blood in cerebrovascular diseases. Eur J Neurol 1999; 6: 437-42.
    • (1999) Eur J Neurol , vol.6 , pp. 437-442
    • Pelidou, S.H.1    Kostulas, N.2    Matusevicius, D.3
  • 80
    • 43049124901 scopus 로고    scopus 로고
    • A Shift from type-1 towards type-2 cytokine expression in peripheral blood T-cells in post-stroke patients: A beneficial modulatory effect to the progression of atherogenesis
    • Theodorou GL, Ellul J, Mougiou A, Mouzaki A, Karakantza M. A Shift from type-1 towards type-2 cytokine expression in peripheral blood T-cells in post-stroke patients: A beneficial modulatory effect to the progression of atherogenesis. Cerebrovasc Dis 2005; 19: 46.
    • (2005) Cerebrovasc Dis , vol.19 , pp. 46
    • Theodorou, G.L.1    Ellul, J.2    Mougiou, A.3    Mouzaki, A.4    Karakantza, M.5
  • 81
    • 0037320943 scopus 로고    scopus 로고
    • Stroke genetics update
    • Alberts MJ. Stroke genetics update. Stroke 2003; 34: 342-4.
    • (2003) Stroke , vol.34 , pp. 342-344
    • Alberts, M.J.1
  • 82
    • 12844271083 scopus 로고    scopus 로고
    • Update on the genetics of stroke and cerebrovascular disease 2004
    • Alberts MJ, Tournier-Lasserve E. Update on the genetics of stroke and cerebrovascular disease 2004. Stroke 2005; 36: 179-81.
    • (2005) Stroke , vol.36 , pp. 179-181
    • Alberts, M.J.1    Tournier-Lasserve, E.2
  • 83
    • 16844372703 scopus 로고    scopus 로고
    • Genetic influences on outcome following acute neurological insults
    • Waters RJ, Nicoll JA. Genetic influences on outcome following acute neurological insults. Curr Opin Crit Care 2005; 11: 105-10.
    • (2005) Curr Opin Crit Care , vol.11 , pp. 105-110
    • Waters, R.J.1    Nicoll, J.A.2
  • 84
    • 7644222570 scopus 로고    scopus 로고
    • Immunogenetic susceptibility of atherosclerotic stroke: Implications on current and future treatment of vascular inflammation
    • DeGraba TJ. Immunogenetic susceptibility of atherosclerotic stroke: implications on current and future treatment of vascular inflammation. Stroke 2004; 35: 2712-9.
    • (2004) Stroke , vol.35 , pp. 2712-2719
    • DeGraba, T.J.1
  • 85
    • 33846597592 scopus 로고    scopus 로고
    • Update on the genetics of stroke and cerebrovascular disease 2006
    • Dichgans M, Hegele RA. Update on the genetics of stroke and cerebrovascular disease 2006. Stroke 2007; 38: 216-8.
    • (2007) Stroke , vol.38 , pp. 216-218
    • Dichgans, M.1    Hegele, R.A.2
  • 86
    • 18544382182 scopus 로고    scopus 로고
    • Aspects of gene polymorphisms in cerebral infarction: Inflammatory cytokines
    • Um JY, Jeong HJ, Park RK, Hong SH, Kim HM. Aspects of gene polymorphisms in cerebral infarction: inflammatory cytokines. Cell Mol Life Sci 2005; 62: 824-33.
    • (2005) Cell Mol Life Sci , vol.62 , pp. 824-833
    • Um, J.Y.1    Jeong, H.J.2    Park, R.K.3    Hong, S.H.4    Kim, H.M.5
  • 87
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello CA. Biologic basis for interleukin-1 in disease. Blood 1996; 87: 2095-147.
    • (1996) Blood , vol.87 , pp. 2095-2147
    • Dinarello, C.A.1
  • 88
    • 0027212397 scopus 로고
    • Polymorphism in human IL-1 receptor antagonist gene intron 2 is caused by variable numbers of an 86-bp tandem repeat
    • Tarlow JK, Blakemore AI, Lennard A, et al. Polymorphism in human IL-1 receptor antagonist gene intron 2 is caused by variable numbers of an 86-bp tandem repeat. Hum Genet 1993; 91: 403-4.
    • (1993) Hum Genet , vol.91 , pp. 403-404
    • Tarlow, J.K.1    Blakemore, A.I.2    Lennard, A.3
  • 89
    • 0028913484 scopus 로고
    • Cytokine production by normal human monocytes: Inter-subject variation and relationship to an IL-1 receptor antagonist (IL-1Ra) gene polymorphism
    • Danis VA, Millington M, Hyland VJ, Grennan D. Cytokine production by normal human monocytes: inter-subject variation and relationship to an IL-1 receptor antagonist (IL-1Ra) gene polymorphism. Clin Exp Immunol 1995; 99: 303-10.
    • (1995) Clin Exp Immunol , vol.99 , pp. 303-310
    • Danis, V.A.1    Millington, M.2    Hyland, V.J.3    Grennan, D.4
  • 90
    • 0031955425 scopus 로고    scopus 로고
    • Presence of the IL-1RA allele 2 (IL1RN*2) is associated with enhanced IL-1beta production in vitro
    • Santtila S, Savinainen K, Hurme M. Presence of the IL-1RA allele 2 (IL1RN*2) is associated with enhanced IL-1beta production in vitro. Scand J Immunol 1998; 47: 195-8.
    • (1998) Scand J Immunol , vol.47 , pp. 195-198
    • Santtila, S.1    Savinainen, K.2    Hurme, M.3
  • 91
    • 0026652591 scopus 로고
    • A TaqI polymorphism in the human interleukin-1 beta (IL-1 beta) gene correlates with IL-1 beta secretion in vitro
    • Pociot F, Molvig J, Wogensen L, Worsaae H, Nerup J. A TaqI polymorphism in the human interleukin-1 beta (IL-1 beta) gene correlates with IL-1 beta secretion in vitro. Eur J Clin Invest 1992; 22: 396-402.
    • (1992) Eur J Clin Invest , vol.22 , pp. 396-402
    • Pociot, F.1    Molvig, J.2    Wogensen, L.3    Worsaae, H.4    Nerup, J.5
  • 92
    • 0033764373 scopus 로고    scopus 로고
    • Interleukin-1 receptor antagonist expression in human endothelial cells and atherosclerosis
    • Dewberry R, Holden H, Crossman D, Francis S. Interleukin-1 receptor antagonist expression in human endothelial cells and atherosclerosis. Arterioscler Thromb Vasc Biol 2000; 20: 2394-400.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2394-2400
    • Dewberry, R.1    Holden, H.2    Crossman, D.3    Francis, S.4
  • 93
    • 0037269189 scopus 로고    scopus 로고
    • Relevance of interleukin-1 receptor antagonist intron-2 polymorphism in ischemic stroke
    • Seripa D, Dobrina A, Margaglione M, et al. Relevance of interleukin-1 receptor antagonist intron-2 polymorphism in ischemic stroke. Cerebrovasc Dis 2003; 15: 276-81.
    • (2003) Cerebrovasc Dis , vol.15 , pp. 276-281
    • Seripa, D.1    Dobrina, A.2    Margaglione, M.3
  • 94
    • 0042594440 scopus 로고    scopus 로고
    • Interleukin-1 gene cluster polymorphisms in cerebral infarction
    • Um JY, Moon KS, Lee KM, Kim HM. Interleukin-1 gene cluster polymorphisms in cerebral infarction. Cytokine 2003; 23: 41-6.
    • (2003) Cytokine , vol.23 , pp. 41-46
    • Um, J.Y.1    Moon, K.S.2    Lee, K.M.3    Kim, H.M.4
  • 95
    • 10744224902 scopus 로고    scopus 로고
    • Susceptibility for ischemic stroke in Korean population is associated with polymorphisms of the interleukin-1 receptor antagonist and tumor necrosis factor-alpha genes, but not the interleukin-1beta gene
    • Lee BC, Ahn SY, Doo HK, et al. Susceptibility for ischemic stroke in Korean population is associated with polymorphisms of the interleukin-1 receptor antagonist and tumor necrosis factor-alpha genes, but not the interleukin-1beta gene. Neurosci Lett 2004; 357: 33-6.
    • (2004) Neurosci Lett , vol.357 , pp. 33-36
    • Lee, B.C.1    Ahn, S.Y.2    Doo, H.K.3
  • 96
    • 14844302204 scopus 로고    scopus 로고
    • The IL-6 G-174C polymorphism may be associated with ischaemic stroke in patients without a history of hypertension
    • Balding J, Livingstone WJ, Pittock SJ, et al. The IL-6 G-174C polymorphism may be associated with ischaemic stroke in patients without a history of hypertension. Ir J Med Sci 2004; 173: 200-3.
    • (2004) Ir J Med Sci , vol.173 , pp. 200-203
    • Balding, J.1    Livingstone, W.J.2    Pittock, S.J.3
  • 97
    • 11844249293 scopus 로고    scopus 로고
    • Polymorphisms of IL-1β, IL-1Ra, and TNF-α Genes: A Nested Case-Control Study of Their Association With Risk for Stroke
    • Cvetkovic JT, Wiklund P, Ahmed E, et al. Polymorphisms of IL-1β, IL-1Ra, and TNF-α Genes: A Nested Case-Control Study of Their Association With Risk for Stroke. J Stroke Cerebrovasc Dis 2005; 14: 29-35.
    • (2005) J Stroke Cerebrovasc Dis , vol.14 , pp. 29-35
    • Cvetkovic, J.T.1    Wiklund, P.2    Ahmed, E.3
  • 98
    • 33746630277 scopus 로고    scopus 로고
    • Polymorphisms of the inflammatory system and risk of ischemic cerebrovascular events
    • Lalouschek W, Schillinger M, Hsieh K, et al. Polymorphisms of the inflammatory system and risk of ischemic cerebrovascular events. Clin Chem Lab Med 2006; 44: 918-23.
    • (2006) Clin Chem Lab Med , vol.44 , pp. 918-923
    • Lalouschek, W.1    Schillinger, M.2    Hsieh, K.3
  • 99
    • 33845286862 scopus 로고    scopus 로고
    • Association of interleukin-1 gene cluster polymorphisms with ischemic stroke in a Chinese population
    • Lai J, Zhou D, Xia S, et al. Association of interleukin-1 gene cluster polymorphisms with ischemic stroke in a Chinese population. Neurol India 2006; 54: 366-9.
    • (2006) Neurol India , vol.54 , pp. 366-369
    • Lai, J.1    Zhou, D.2    Xia, S.3
  • 100
    • 34247891781 scopus 로고    scopus 로고
    • IL1RN VNTR polymorphism in ischemic stroke: Analysis in 3 populations
    • Worrall BB, Brott TG, Brown RD, Jr., et al. IL1RN VNTR polymorphism in ischemic stroke: analysis in 3 populations. Stroke 2007; 38: 1189-96.
    • (2007) Stroke , vol.38 , pp. 1189-1196
    • Worrall, B.B.1    Brott, T.G.2    Brown Jr., R.D.3
  • 101
    • 33846856909 scopus 로고    scopus 로고
    • IL1RN intron 2 polymorphism caused by variable number tandem repeats is associated with 1-year outcome in patients with ischaemic stroke
    • Gromadzka G, Sarzynska-Dlugosz I, Czlonkowska A. IL1RN intron 2 polymorphism caused by variable number tandem repeats is associated with 1-year outcome in patients with ischaemic stroke. J Neurol Neurosurg Psychiatry 2007; 78: 183-6.
    • (2007) J Neurol Neurosurg Psychiatry , vol.78 , pp. 183-186
    • Gromadzka, G.1    Sarzynska-Dlugosz, I.2    Czlonkowska, A.3
  • 102
    • 0032899896 scopus 로고    scopus 로고
    • IL1B gene polymorphisms influence the course and severity of inflammatory bowel disease
    • Nemetz A, Nosti-Escanilla MP, Molnar T, et al. IL1B gene polymorphisms influence the course and severity of inflammatory bowel disease. Immunogenetics 1999; 49: 527-31.
    • (1999) Immunogenetics , vol.49 , pp. 527-531
    • Nemetz, A.1    Nosti-Escanilla, M.P.2    Molnar, T.3
  • 103
    • 0031927564 scopus 로고    scopus 로고
    • IL-1 receptor antagonist (IL-1Ra) plasma levels are co-ordinately regulated by both IL-1Ra and IL-1beta genes
    • Hurme M, Santtila S. IL-1 receptor antagonist (IL-1Ra) plasma levels are co-ordinately regulated by both IL-1Ra and IL-1beta genes. Eur J Immunol 1998; 28: 2598-602.
    • (1998) Eur J Immunol , vol.28 , pp. 2598-2602
    • Hurme, M.1    Santtila, S.2
  • 104
    • 0347755453 scopus 로고    scopus 로고
    • Lack of association between interleukin-1 beta polymorphism (-511) and ischaemic stroke
    • Dziedzic T, Slowik A, Pera J, Szczudlik A. Lack of association between interleukin-1 beta polymorphism (-511) and ischaemic stroke. J Neurol Neurosurg Psychiatry 2004; 75: 170-1.
    • (2004) J Neurol Neurosurg Psychiatry , vol.75 , pp. 170-171
    • Dziedzic, T.1    Slowik, A.2    Pera, J.3    Szczudlik, A.4
  • 105
    • 19944427889 scopus 로고    scopus 로고
    • Polymorphisms of the interleukin-1beta gene affect the risk of myocardial infarction and ischemic stroke at young age and the response of mononuclear cells to stimulation in vitro
    • Iacoviello L, Di Castelnuovo A, Gattone M, et al. Polymorphisms of the interleukin-1beta gene affect the risk of myocardial infarction and ischemic stroke at young age and the response of mononuclear cells to stimulation in vitro. Arterioscler Thromb Vasc Biol 2005; 25: 222-7.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 222-227
    • Iacoviello, L.1    Di Castelnuovo, A.2    Gattone, M.3
  • 106
    • 27644522711 scopus 로고    scopus 로고
    • Interleukin 1 beta polymorphism (-511) and risk of stroke due to small vessel disease
    • Dziedzic T, Slowik A, Pera J, Szczudlik A. Interleukin 1 beta polymorphism (-511) and risk of stroke due to small vessel disease. Cerebrovasc Dis 2005; 20: 299-303.
    • (2005) Cerebrovasc Dis , vol.20 , pp. 299-303
    • Dziedzic, T.1    Slowik, A.2    Pera, J.3    Szczudlik, A.4
  • 107
    • 29244433512 scopus 로고    scopus 로고
    • A role of TNF-alpha gene variant on juvenile ischemic stroke: A case-control study
    • Rubattu S, Speranza R, Ferrari M, et al. A role of TNF-alpha gene variant on juvenile ischemic stroke: a case-control study. Eur J Neurol 2005; 12: 989-93.
    • (2005) Eur J Neurol , vol.12 , pp. 989-993
    • Rubattu, S.1    Speranza, R.2    Ferrari, M.3
  • 109
    • 1242285629 scopus 로고    scopus 로고
    • Polymorphism in the P-selectin and interleukin-4 genes as determinants of stroke: A population-based, prospective genetic analysis
    • Zee RY, Cook NR, Cheng S, et al. Polymorphism in the P-selectin and interleukin-4 genes as determinants of stroke: a population-based, prospective genetic analysis. Hum Mol Genet 2004; 13: 389-96.
    • (2004) Hum Mol Genet , vol.13 , pp. 389-396
    • Zee, R.Y.1    Cook, N.R.2    Cheng, S.3
  • 110
    • 33947166241 scopus 로고    scopus 로고
    • The glu298asp polymorphism in the nitric oxide synthase 3 gene is associated with the risk of ischemic stroke in two large independent case-control studies
    • Berger K, Stogbauer F, Stoll M, et al. The glu298asp polymorphism in the nitric oxide synthase 3 gene is associated with the risk of ischemic stroke in two large independent case-control studies. Hum Genet 2007; 121: 169-78.
    • (2007) Hum Genet , vol.121 , pp. 169-178
    • Berger, K.1    Stogbauer, F.2    Stoll, M.3
  • 111
    • 0036323332 scopus 로고    scopus 로고
    • Cloning and functional analysis of the allelic polymorphism in the transcription regulatory region of interleukin-1 alpha
    • Dominici R, Cattaneo M, Malferrari G, et al. Cloning and functional analysis of the allelic polymorphism in the transcription regulatory region of interleukin-1 alpha. Immunogenetics 2002; 54: 82-6.
    • (2002) Immunogenetics , vol.54 , pp. 82-86
    • Dominici, R.1    Cattaneo, M.2    Malferrari, G.3
  • 112
    • 0031204171 scopus 로고    scopus 로고
    • Gingival crevicular interleukin-1 and interleukin-1 receptor antagonist levels in periodontally healthy and diseased sites
    • Ishihara Y, Nishihara T, Kuroyanagi T, et al. Gingival crevicular interleukin-1 and interleukin-1 receptor antagonist levels in periodontally healthy and diseased sites. J Periodontal Res 1997; 32: 524-9.
    • (1997) J Periodontal Res , vol.32 , pp. 524-529
    • Ishihara, Y.1    Nishihara, T.2    Kuroyanagi, T.3
  • 113
    • 0026906857 scopus 로고
    • Single base polymorphism in the human tumour necrosis factor alpha (TNF alpha) gene detectable by NcoI restriction of PCR product
    • Wilson AG, di Giovine FS, Blakemore AI, Duff GW. Single base polymorphism in the human tumour necrosis factor alpha (TNF alpha) gene detectable by NcoI restriction of PCR product. Hum Mol Genet 1992; 1: 353.
    • (1992) Hum Mol Genet , vol.1 , pp. 353
    • Wilson, A.G.1    di Giovine, F.S.2    Blakemore, A.I.3    Duff, G.W.4
  • 114
    • 0032881603 scopus 로고    scopus 로고
    • Impact of the -308 TNF promoter polymorphism on the transcriptional regulation of the TNF gene: Relevance to disease
    • Abraham LJ, Kroeger KM. Impact of the -308 TNF promoter polymorphism on the transcriptional regulation of the TNF gene: relevance to disease. J Leukoc Biol 1999; 66: 562-6.
    • (1999) J Leukoc Biol , vol.66 , pp. 562-566
    • Abraham, L.J.1    Kroeger, K.M.2
  • 115
    • 0030862033 scopus 로고    scopus 로고
    • The -308 tumor necrosis factor-alpha promoter polymorphism effects transcription
    • Kroeger KM, Carville KS, Abraham LJ. The -308 tumor necrosis factor-alpha promoter polymorphism effects transcription. Mol Immunol 1997; 34: 391-9.
    • (1997) Mol Immunol , vol.34 , pp. 391-399
    • Kroeger, K.M.1    Carville, K.S.2    Abraham, L.J.3
  • 116
    • 9244244710 scopus 로고    scopus 로고
    • Secretion of tumour necrosis factor alpha and lymphotoxin alpha in relation to polymorphisms in the TNF genes and HLA-DR alleles. Relevance for inflammatory bowel disease
    • Bouma G, Crusius JB, Oudkerk Pool M, et al. Secretion of tumour necrosis factor alpha and lymphotoxin alpha in relation to polymorphisms in the TNF genes and HLA-DR alleles. Relevance for inflammatory bowel disease. Scand J Immunol 1996; 43: 456-63.
    • (1996) Scand J Immunol , vol.43 , pp. 456-463
    • Bouma, G.1    Crusius, J.B.2    Oudkerk Pool, M.3
  • 117
    • 0033934788 scopus 로고    scopus 로고
    • Effects of stimulus and cell type on the expression of the -308 tumour necrosis factor promoter polymorphism
    • Kroeger KM, Steer JH, Joyce DA, Abraham LJ. Effects of stimulus and cell type on the expression of the -308 tumour necrosis factor promoter polymorphism. Cytokine 2000; 12: 110-9.
    • (2000) Cytokine , vol.12 , pp. 110-119
    • Kroeger, K.M.1    Steer, J.H.2    Joyce, D.A.3    Abraham, L.J.4
  • 118
    • 0030572673 scopus 로고    scopus 로고
    • Gene polymorphism at position -308 of the tumor-necrosis-factor-alpha (TNF-alpha) in multiple sclerosis and it's influence on the regulation of TNF-alpha production
    • Braun N, Michel U, Ernst BP, et al. Gene polymorphism at position -308 of the tumor-necrosis-factor-alpha (TNF-alpha) in multiple sclerosis and it's influence on the regulation of TNF-alpha production. Neurosci Lett 1996; 215: 75-8.
    • (1996) Neurosci Lett , vol.215 , pp. 75-78
    • Braun, N.1    Michel, U.2    Ernst, B.P.3
  • 119
    • 0030868696 scopus 로고    scopus 로고
    • DNA polymorphisms and mutations of the tumor necrosis factor-alpha (TNF-alpha) promoter in Langerhans cell histiocytosis (LCH)
    • Wu WS, McClain KL. DNA polymorphisms and mutations of the tumor necrosis factor-alpha (TNF-alpha) promoter in Langerhans cell histiocytosis (LCH). J Interferon Cytokine Res 1997; 17: 631-5.
    • (1997) J Interferon Cytokine Res , vol.17 , pp. 631-635
    • Wu, W.S.1    McClain, K.L.2
  • 120
    • 0030954180 scopus 로고    scopus 로고
    • Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation
    • Wilson AG, Symons JA, McDowell TL, McDevitt HO, Duff GW. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc Natl Acad Sci USA 1997; 94: 3195-9.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3195-3199
    • Wilson, A.G.1    Symons, J.A.2    McDowell, T.L.3    McDevitt, H.O.4    Duff, G.W.5
  • 121
    • 0029966034 scopus 로고
    • Relevance of the tumor necrosis factor alpha (TNF alpha) -308 promoter polymorphism in TNF alpha gene regulation
    • Brinkman BM, Zuijdeest D, Kaijzel EL, Breedveld FC, Verweij CL. Relevance of the tumor necrosis factor alpha (TNF alpha) -308 promoter polymorphism in TNF alpha gene regulation. J Inflamm 1995; 46: 32-41.
    • (1995) J Inflamm , vol.46 , pp. 32-41
    • Brinkman, B.M.1    Zuijdeest, D.2    Kaijzel, E.L.3    Breedveld, F.C.4    Verweij, C.L.5
  • 122
    • 0035927489 scopus 로고    scopus 로고
    • Functional analysis of linker-scan mutants spanning the -376, -308, -244, and -238 polymorphic sites of the TNF-alpha promoter
    • Bayley JP, de Rooij H, van den Elsen PJ, Huizinga TW, Verweij CL. Functional analysis of linker-scan mutants spanning the -376, -308, -244, and -238 polymorphic sites of the TNF-alpha promoter. Cytokine 2001; 14: 316-23.
    • (2001) Cytokine , vol.14 , pp. 316-323
    • Bayley, J.P.1    de Rooij, H.2    van den Elsen, P.J.3    Huizinga, T.W.4    Verweij, C.L.5
  • 123
    • 12244278306 scopus 로고    scopus 로고
    • Are cytokine gene polymorphisms related to in vitro cytokine production profiles?
    • Warle MC, Farhan A, Metselaar HJ, et al. Are cytokine gene polymorphisms related to in vitro cytokine production profiles? Liver Transpl 2003; 9: 170-81.
    • (2003) Liver Transpl , vol.9 , pp. 170-181
    • Warle, M.C.1    Farhan, A.2    Metselaar, H.J.3
  • 124
    • 0029880580 scopus 로고
    • 308 tumor necrosis factor (TNF) polymorphism is not associated with survival in severe sepsis and is unrelated to lipopolysaccharide inducibility of the human TNF promoter
    • Stuber F, Udalova IA, Book M, et al. -308 tumor necrosis factor (TNF) polymorphism is not associated with survival in severe sepsis and is unrelated to lipopolysaccharide inducibility of the human TNF promoter. J Inflamm 1995; 46: 42-50.
    • (1995) J Inflamm , vol.46 , pp. 42-50
    • Stuber, F.1    Udalova, I.A.2    Book, M.3
  • 125
    • 1342328026 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha gene polymorphism is associated with cerebral infarction
    • Um JY, Kim HM. Tumor necrosis factor alpha gene polymorphism is associated with cerebral infarction. Brain Res Mol Brain Res 2004; 122: 99-102.
    • (2004) Brain Res Mol Brain Res , vol.122 , pp. 99-102
    • Um, J.Y.1    Kim, H.M.2
  • 126
    • 14144253851 scopus 로고    scopus 로고
    • TNF-alpha -308G/A and IL-6 -174 G/C polymorphisms in the Turkish pediatric stroke patients
    • Karahan ZC, Deda G, Sipahi T, Elhan AH, Akar N. TNF-alpha -308G/A and IL-6 -174 G/C polymorphisms in the Turkish pediatric stroke patients. Thromb Res 2005; 115: 393-8.
    • (2005) Thromb Res , vol.115 , pp. 393-398
    • Karahan, Z.C.1    Deda, G.2    Sipahi, T.3    Elhan, A.H.4    Akar, N.5
  • 127
    • 24644484080 scopus 로고    scopus 로고
    • Genetic polymorphisms and the risk of stroke after cardiac surgery
    • Grocott HP, White WD, Morris RW, et al. Genetic polymorphisms and the risk of stroke after cardiac surgery. Stroke 2005; 36: 1854-8.
    • (2005) Stroke , vol.36 , pp. 1854-1858
    • Grocott, H.P.1    White, W.D.2    Morris, R.W.3
  • 128
    • 33644986199 scopus 로고    scopus 로고
    • Decreased frequency of the TNF2 allele of TNF-alpha -308 promoter polymorphism is associated with lacunar infarction
    • Harcos P, Laki J, Kiszel P, et al. Decreased frequency of the TNF2 allele of TNF-alpha -308 promoter polymorphism is associated with lacunar infarction. Cytokine 2006; 33: 100-5.
    • (2006) Cytokine , vol.33 , pp. 100-105
    • Harcos, P.1    Laki, J.2    Kiszel, P.3
  • 129
    • 34548269532 scopus 로고    scopus 로고
    • Hoppe C, Klitz W, D'Harlingue K, et al. Confirmation of an association between the TNF(-308) promoter polymorphism and stroke risk in children with sickle cell anemia. Stroke 2007.
    • Hoppe C, Klitz W, D'Harlingue K, et al. Confirmation of an association between the TNF(-308) promoter polymorphism and stroke risk in children with sickle cell anemia. Stroke 2007.
  • 130
    • 0032993434 scopus 로고    scopus 로고
    • A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria
    • Knight JC, Udalova I, Hill AV, et al. A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria. Nat Genet 1999; 22: 145-50.
    • (1999) Nat Genet , vol.22 , pp. 145-150
    • Knight, J.C.1    Udalova, I.2    Hill, A.V.3
  • 131
    • 0034099699 scopus 로고    scopus 로고
    • Different transcriptional activity and in vitro TNF-alpha production in psoriasis patients carrying the TNF-alpha 238A promoter polymorphism
    • Kaluza W, Reuss E, Grossmann S, et al. Different transcriptional activity and in vitro TNF-alpha production in psoriasis patients carrying the TNF-alpha 238A promoter polymorphism. J Invest Dermatol 2000; 114: 1180-3.
    • (2000) J Invest Dermatol , vol.114 , pp. 1180-1183
    • Kaluza, W.1    Reuss, E.2    Grossmann, S.3
  • 133
    • 0032837736 scopus 로고    scopus 로고
    • A common functional polymorphism (C - >A substitution at position -863) in the promoter region of the tumour necrosis factor-alpha (TNF-alpha) gene associated with reduced circulating levels of TNF-alpha
    • Skoog T, van't Hooft FM, Kallin B, et al. A common functional polymorphism (C - >A substitution at position -863) in the promoter region of the tumour necrosis factor-alpha (TNF-alpha) gene associated with reduced circulating levels of TNF-alpha. Hum Mol Genet 1999; 8: 1443-9.
    • (1999) Hum Mol Genet , vol.8 , pp. 1443-1449
    • Skoog, T.1    van't Hooft, F.M.2    Kallin, B.3
  • 134
    • 0035835451 scopus 로고    scopus 로고
    • Association between polymorphism in regulatory region of gene encoding tumour necrosis factor alpha and risk of Alzheimer's disease and vascular dementia: A case-control study
    • McCusker SM, Curran MD, Dynan KB, et al. Association between polymorphism in regulatory region of gene encoding tumour necrosis factor alpha and risk of Alzheimer's disease and vascular dementia: a case-control study. Lancet 2001; 357: 436-9.
    • (2001) Lancet , vol.357 , pp. 436-439
    • McCusker, S.M.1    Curran, M.D.2    Dynan, K.B.3
  • 135
    • 0032525156 scopus 로고    scopus 로고
    • Genetic polymorphisms in the tumor necrosis factor locus influence non-Hodgkin's lymphoma outcome
    • Warzocha K, Ribeiro P, Bienvenu J, et al. Genetic polymorphisms in the tumor necrosis factor locus influence non-Hodgkin's lymphoma outcome. Blood 1998; 91: 3574-81.
    • (1998) Blood , vol.91 , pp. 3574-3581
    • Warzocha, K.1    Ribeiro, P.2    Bienvenu, J.3
  • 136
    • 0026089188 scopus 로고
    • Polymorphic structure of the tumor necrosis factor (TNF) locus: An NcoI polymorphism in the first intron of the human TNF-beta gene correlates with a variant amino acid in position 26 and a reduced level of TNF-beta production
    • Messer G, Spengler U, Jung MC, et al. Polymorphic structure of the tumor necrosis factor (TNF) locus: an NcoI polymorphism in the first intron of the human TNF-beta gene correlates with a variant amino acid in position 26 and a reduced level of TNF-beta production. J Exp Med 1991; 173: 209-19.
    • (1991) J Exp Med , vol.173 , pp. 209-219
    • Messer, G.1    Spengler, U.2    Jung, M.C.3
  • 137
    • 0027397580 scopus 로고
    • Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-alpha and TNF-beta by human mononuclear cells: A possible link to insulin-dependent diabetes mellitus
    • Pociot F, Briant L, Jongeneel CV, et al. Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-alpha and TNF-beta by human mononuclear cells: a possible link to insulin-dependent diabetes mellitus. Eur J Immunol 1993; 23: 224-31.
    • (1993) Eur J Immunol , vol.23 , pp. 224-231
    • Pociot, F.1    Briant, L.2    Jongeneel, C.V.3
  • 138
    • 0029922017 scopus 로고    scopus 로고
    • A genomic polymorphism within the tumor necrosis factor locus influences plasma tumor necrosis factor-alpha concentrations and outcome of patients with severe sepsis
    • Stuber F, Petersen M, Bokelmann F, Schade U. A genomic polymorphism within the tumor necrosis factor locus influences plasma tumor necrosis factor-alpha concentrations and outcome of patients with severe sepsis. Crit Care Med 1996; 24: 381-4.
    • (1996) Crit Care Med , vol.24 , pp. 381-384
    • Stuber, F.1    Petersen, M.2    Bokelmann, F.3    Schade, U.4
  • 139
    • 0242552818 scopus 로고    scopus 로고
    • TNF-alpha and TNF-beta gene polymorphisms in cerebral infarction
    • Um JY, An NH, Kim HM. TNF-alpha and TNF-beta gene polymorphisms in cerebral infarction. J Mol Neurosci 2003; 21: 167-71.
    • (2003) J Mol Neurosci , vol.21 , pp. 167-171
    • Um, J.Y.1    An, N.H.2    Kim, H.M.3
  • 140
    • 0030727983 scopus 로고    scopus 로고
    • Increased monocyte TNF-alpha message stability contributes to trauma patients' increased TNF production
    • Furse RK, Kodys K, Zhu D, Miller-Graziano CL. Increased monocyte TNF-alpha message stability contributes to trauma patients' increased TNF production. J Leukoc Biol 1997; 62: 524-34.
    • (1997) J Leukoc Biol , vol.62 , pp. 524-534
    • Furse, R.K.1    Kodys, K.2    Zhu, D.3    Miller-Graziano, C.L.4
  • 141
    • 0033594424 scopus 로고    scopus 로고
    • Genetic variants in the tumor necrosis factor receptor 1 gene in patients with MS
    • Weinshenker BG, Hebrink D, Wingerchuk DM, et al. Genetic variants in the tumor necrosis factor receptor 1 gene in patients with MS. Neurology 1999; 52: 1500-3.
    • (1999) Neurology , vol.52 , pp. 1500-1503
    • Weinshenker, B.G.1    Hebrink, D.2    Wingerchuk, D.M.3
  • 142
    • 0033065921 scopus 로고    scopus 로고
    • Association of tumor necrosis factor receptor 2 (TNFR2) polymorphism with susceptibility to systemic lupus erythematosus
    • Komata T, Tsuchiya N, Matsushita M, Hagiwara K, Tokunaga K. Association of tumor necrosis factor receptor 2 (TNFR2) polymorphism with susceptibility to systemic lupus erythematosus. Tissue Antigens 1999; 53: 527-33.
    • (1999) Tissue Antigens , vol.53 , pp. 527-533
    • Komata, T.1    Tsuchiya, N.2    Matsushita, M.3    Hagiwara, K.4    Tokunaga, K.5
  • 143
    • 0030021055 scopus 로고    scopus 로고
    • The biological effects of interleukin 6
    • Barton BE. The biological effects of interleukin 6. Med Res Rev 1996; 16: 87-109.
    • (1996) Med Res Rev , vol.16 , pp. 87-109
    • Barton, B.E.1
  • 144
    • 0028031990 scopus 로고
    • Interleukin-6 (IL-6) as an anti-inflammatory cytokine: Induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55
    • Tilg H, Trehu E, Atkins MB, Dinarello CA, Mier JW. Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55. Blood 1994; 83: 113-8.
    • (1994) Blood , vol.83 , pp. 113-118
    • Tilg, H.1    Trehu, E.2    Atkins, M.B.3    Dinarello, C.A.4    Mier, J.W.5
  • 145
    • 0142010515 scopus 로고    scopus 로고
    • C-reactive protein and interleukin-6 in vascular disease: Culprits or passive bystanders?
    • Rattazzi M, Puato M, Faggin E, et al. C-reactive protein and interleukin-6 in vascular disease: culprits or passive bystanders? J Hypertens 2003; 21: 1787-803.
    • (2003) J Hypertens , vol.21 , pp. 1787-1803
    • Rattazzi, M.1    Puato, M.2    Faggin, E.3
  • 146
    • 0032535026 scopus 로고    scopus 로고
    • Chronic interleukin-6 alters NMDA receptor-mediated membrane responses and enhances neurotoxicity in developing CNS neurons
    • Qiu Z, Sweeney DD, Netzeband JG, Gruol DL. Chronic interleukin-6 alters NMDA receptor-mediated membrane responses and enhances neurotoxicity in developing CNS neurons. J Neurosci 1998; 18: 10445-56.
    • (1998) J Neurosci , vol.18 , pp. 10445-10456
    • Qiu, Z.1    Sweeney, D.D.2    Netzeband, J.G.3    Gruol, D.L.4
  • 147
    • 0032189103 scopus 로고    scopus 로고
    • The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis
    • Fishman D, Faulds G, Jeffery R, et al. The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest 1998; 102: 1369-76.
    • (1998) J Clin Invest , vol.102 , pp. 1369-1376
    • Fishman, D.1    Faulds, G.2    Jeffery, R.3
  • 148
    • 7044231463 scopus 로고    scopus 로고
    • Genetic predisposition of the interleukin-6 response to inflammation: Implications for a variety of major diseases?
    • Bennermo M, Held C, Stemme S, et al. Genetic predisposition of the interleukin-6 response to inflammation: implications for a variety of major diseases? Clin Chem 2004; 50: 2136-40.
    • (2004) Clin Chem , vol.50 , pp. 2136-2140
    • Bennermo, M.1    Held, C.2    Stemme, S.3
  • 149
    • 0035889519 scopus 로고    scopus 로고
    • Relation of the -174 G/C polymorphism of interleukin-6 to interleukin-6 plasma levels and to length of hospitalization after surgical coronary revascularization
    • Burzotta F, Iacoviello L, Di Castelnuovo A, et al. Relation of the -174 G/C polymorphism of interleukin-6 to interleukin-6 plasma levels and to length of hospitalization after surgical coronary revascularization. Am J Cardiol 2001; 88: 1125-8.
    • (2001) Am J Cardiol , vol.88 , pp. 1125-1128
    • Burzotta, F.1    Iacoviello, L.2    Di Castelnuovo, A.3
  • 150
    • 1642492772 scopus 로고    scopus 로고
    • The interleukin-6 G(-174)C promoter polymorphism does not determine plasma interleukin-6 concentrations in experimental endotoxemia in humans
    • Endler G, Marsik C, Joukhadar C, et al. The interleukin-6 G(-174)C promoter polymorphism does not determine plasma interleukin-6 concentrations in experimental endotoxemia in humans. Clin Chem 2004; 50: 195-200.
    • (2004) Clin Chem , vol.50 , pp. 195-200
    • Endler, G.1    Marsik, C.2    Joukhadar, C.3
  • 151
    • 0036373824 scopus 로고    scopus 로고
    • The interleukin-6 G(-174)C promoter polymorphism in the LURIC cohort: No association with plasma interleukin-6, coronary artery disease, and myocardial infarction
    • Nauck M, Winkelmann BR, Hoffmann MM, et al. The interleukin-6 G(-174)C promoter polymorphism in the LURIC cohort: no association with plasma interleukin-6, coronary artery disease, and myocardial infarction. J Mol Med 2002; 80: 507-13.
    • (2002) J Mol Med , vol.80 , pp. 507-513
    • Nauck, M.1    Winkelmann, B.R.2    Hoffmann, M.M.3
  • 152
    • 0036152550 scopus 로고    scopus 로고
    • Effect of the interleukin-6 promoter polymorphism (-174 G/C) on the incidence and outcome of sepsis
    • Schluter B, Raufhake C, Erren M, et al. Effect of the interleukin-6 promoter polymorphism (-174 G/C) on the incidence and outcome of sepsis. Crit Care Med 2002; 30: 32-7.
    • (2002) Crit Care Med , vol.30 , pp. 32-37
    • Schluter, B.1    Raufhake, C.2    Erren, M.3
  • 153
    • 0035066753 scopus 로고    scopus 로고
    • The promoter polymorphism of the interleukin-6 gene regulates interleukin-6 production in neonates but not in adults
    • Kilpinen S, Hulkkonen J, Wang XY, Hurme M. The promoter polymorphism of the interleukin-6 gene regulates interleukin-6 production in neonates but not in adults. Eur Cytokine Netw 2001; 12: 62-8.
    • (2001) Eur Cytokine Netw , vol.12 , pp. 62-68
    • Kilpinen, S.1    Hulkkonen, J.2    Wang, X.Y.3    Hurme, M.4
  • 154
    • 0035573649 scopus 로고    scopus 로고
    • Interleukin-6 gene -174g>c and -572g>c promoter polymorphisms are strong predictors of plasma interleukin-6 levels after coronary artery bypass surgery
    • Brull DJ, Montgomery HE, Sanders J, et al. Interleukin-6 gene -174g>c and -572g>c promoter polymorphisms are strong predictors of plasma interleukin-6 levels after coronary artery bypass surgery. Arterioscler Thromb Vasc Biol 2001; 21: 1458-63.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1458-1463
    • Brull, D.J.1    Montgomery, H.E.2    Sanders, J.3
  • 155
    • 0037312898 scopus 로고    scopus 로고
    • The C-174G promoter polymorphism of the IL-6 gene affects energy expenditure and insulin sensitivity
    • Kubaszek A, Pihlajamaki J, Punnonen K, et al. The C-174G promoter polymorphism of the IL-6 gene affects energy expenditure and insulin sensitivity. Diabetes 2003; 52: 558-61.
    • (2003) Diabetes , vol.52 , pp. 558-561
    • Kubaszek, A.1    Pihlajamaki, J.2    Punnonen, K.3
  • 156
    • 0036920138 scopus 로고    scopus 로고
    • In the elderly, interleukin-6 plasma levels and the -174G>C polymorphism are associated with the development of cardiovascular disease
    • Jenny NS, Tracy RP, Ogg MS, et al. In the elderly, interleukin-6 plasma levels and the -174G>C polymorphism are associated with the development of cardiovascular disease. Arterioscler Thromb Vasc Biol 2002; 22: 2066-71.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 2066-2071
    • Jenny, N.S.1    Tracy, R.P.2    Ogg, M.S.3
  • 157
    • 0036090605 scopus 로고    scopus 로고
    • Carotid intima-media thickness is associated with allelic variants of stromelysin-1, interleukin-6, and hepatic lipase genes: The Northern Manhattan Prospective Cohort Study
    • Rundek T, Elkind MS, Pittman J, et al. Carotid intima-media thickness is associated with allelic variants of stromelysin-1, interleukin-6, and hepatic lipase genes: the Northern Manhattan Prospective Cohort Study. Stroke 2002; 33: 1420-3.
    • (2002) Stroke , vol.33 , pp. 1420-1423
    • Rundek, T.1    Elkind, M.S.2    Pittman, J.3
  • 158
    • 0040780540 scopus 로고    scopus 로고
    • Cooperative influence of genetic polymorphisms on interleukin 6 transcriptional regulation
    • Terry CF, Loukaci V, Green FR. Cooperative influence of genetic polymorphisms on interleukin 6 transcriptional regulation. J Biol Chem 2000; 275: 18138-44.
    • (2000) J Biol Chem , vol.275 , pp. 18138-18144
    • Terry, C.F.1    Loukaci, V.2    Green, F.R.3
  • 159
    • 0041903685 scopus 로고    scopus 로고
    • Multiple levels of regulation of the interleukin-6 system in stroke
    • Acalovschi D, Wiest T, Hartmann M, et al. Multiple levels of regulation of the interleukin-6 system in stroke. Stroke 2003; 34: 1864-9.
    • (2003) Stroke , vol.34 , pp. 1864-1869
    • Acalovschi, D.1    Wiest, T.2    Hartmann, M.3
  • 160
  • 161
    • 0242317416 scopus 로고    scopus 로고
    • The (-174) G/C polymorphism in the interleukin-6 gene is associated with the severity of acute cerebrovascular events
    • Greisenegger S, Endler G, Haering D, et al. The (-174) G/C polymorphism in the interleukin-6 gene is associated with the severity of acute cerebrovascular events. Thromb Res 2003; 110: 181-6.
    • (2003) Thromb Res , vol.110 , pp. 181-186
    • Greisenegger, S.1    Endler, G.2    Haering, D.3
  • 162
    • 0037052758 scopus 로고    scopus 로고
    • A -174G/C polymorphism of the interleukin-6 gene in patients with lacunar infarction
    • Revilla M, Obach V, Cervera A, et al. A -174G/C polymorphism of the interleukin-6 gene in patients with lacunar infarction. Neurosci Lett 2002; 324: 29-32.
    • (2002) Neurosci Lett , vol.324 , pp. 29-32
    • Revilla, M.1    Obach, V.2    Cervera, A.3
  • 163
    • 14044251443 scopus 로고    scopus 로고
    • The -174G/C polymorphism of the interleukin 6 gene is a hallmark of lacunar stroke and not other ischemic stroke phenotypes
    • Chamorro A, Revilla M, Obach V, Vargas M, Planas AM. The -174G/C polymorphism of the interleukin 6 gene is a hallmark of lacunar stroke and not other ischemic stroke phenotypes. Cerebrovasc Dis 2005; 19: 91-5.
    • (2005) Cerebrovasc Dis , vol.19 , pp. 91-95
    • Chamorro, A.1    Revilla, M.2    Obach, V.3    Vargas, M.4    Planas, A.M.5
  • 164
    • 34548523829 scopus 로고    scopus 로고
    • Genetic risk for atherothrombotic cerebral infarction in individuals stratified by sex or conventional risk factors for atherosclerosis
    • Yamaguchi S, Yamada Y, Metoki N, et al. Genetic risk for atherothrombotic cerebral infarction in individuals stratified by sex or conventional risk factors for atherosclerosis. Int J Mol Med 2006; 18: 871-83.
    • (2006) Int J Mol Med , vol.18 , pp. 871-883
    • Yamaguchi, S.1    Yamada, Y.2    Metoki, N.3
  • 165
    • 0037383552 scopus 로고    scopus 로고
    • Synergistic effect of -174 G/C polymorphism of the interleukin-6 gene promoter and 469 E/K polymorphism of the intercellular adhesion molecule-1 gene in Italian patients with history of ischemic stroke
    • Pola R, Flex A, Gaetani E, et al. Synergistic effect of -174 G/C polymorphism of the interleukin-6 gene promoter and 469 E/K polymorphism of the intercellular adhesion molecule-1 gene in Italian patients with history of ischemic stroke. Stroke 2003; 34: 881-5.
    • (2003) Stroke , vol.34 , pp. 881-885
    • Pola, R.1    Flex, A.2    Gaetani, E.3
  • 166
    • 4744362285 scopus 로고    scopus 로고
    • Proinflammatory genetic profiles in subjects with history of ischemic stroke
    • Flex A, Gaetani E, Papaleo P, et al. Proinflammatory genetic profiles in subjects with history of ischemic stroke. Stroke 2004; 35: 2270-5.
    • (2004) Stroke , vol.35 , pp. 2270-2275
    • Flex, A.1    Gaetani, E.2    Papaleo, P.3
  • 167
    • 25444508186 scopus 로고    scopus 로고
    • Serum interleukin-6 soluble receptor in relation to interleukin-6 in stroke patients
    • Dziedzic T, Gryz EA, Turaj W, Slowik A, Szczudlik A. Serum interleukin-6 soluble receptor in relation to interleukin-6 in stroke patients. J Mol Neurosci 2004; 24: 293-8.
    • (2004) J Mol Neurosci , vol.24 , pp. 293-298
    • Dziedzic, T.1    Gryz, E.A.2    Turaj, W.3    Slowik, A.4    Szczudlik, A.5
  • 168
    • 0032916280 scopus 로고    scopus 로고
    • Interleukin-8 mediates downregulation of tissue inhibitor of metalloproteinase-1 expression in cholesterol-loaded human macrophages: Relevance to stability of atherosclerotic plaque
    • Moreau M, Brocheriou I, Petit L, et al. Interleukin-8 mediates downregulation of tissue inhibitor of metalloproteinase-1 expression in cholesterol-loaded human macrophages: relevance to stability of atherosclerotic plaque. Circulation 1999; 99: 420-6.
    • (1999) Circulation , vol.99 , pp. 420-426
    • Moreau, M.1    Brocheriou, I.2    Petit, L.3
  • 169
    • 0030871256 scopus 로고    scopus 로고
    • Prevention of cerebral edema and infarct in cerebral reperfusion injury by an antibody to interleukin-8
    • Matsumoto T, Ikeda K, Mukaida N, et al. Prevention of cerebral edema and infarct in cerebral reperfusion injury by an antibody to interleukin-8. Lab Invest 1997; 77: 119-25.
    • (1997) Lab Invest , vol.77 , pp. 119-125
    • Matsumoto, T.1    Ikeda, K.2    Mukaida, N.3
  • 170
    • 0035780222 scopus 로고    scopus 로고
    • Increased cytokine release by leucocytes in survivors of stroke at young age
    • Grau AJ, Aulmann M, Lichy C, et al. Increased cytokine release by leucocytes in survivors of stroke at young age. Eur J Clin Invest 2001; 31: 999-1006.
    • (2001) Eur J Clin Invest , vol.31 , pp. 999-1006
    • Grau, A.J.1    Aulmann, M.2    Lichy, C.3
  • 171
    • 0022353594 scopus 로고
    • Serological, biochemical, and functional identity of B cell-stimulatory factor 1 and B cell differentiation factor for IgG1
    • Vitetta ES, Ohara J, Myers CD, et al. Serological, biochemical, and functional identity of B cell-stimulatory factor 1 and B cell differentiation factor for IgG1. J Exp Med 1985; 162: 1726-31.
    • (1985) J Exp Med , vol.162 , pp. 1726-1731
    • Vitetta, E.S.1    Ohara, J.2    Myers, C.D.3
  • 172
    • 0028789831 scopus 로고
    • Promoter polymorphisms in the chromosome 5 gene cluster in asthma and atopy
    • discussion 95-6
    • Rosenwasser LJ, Klemm DJ, Dresback JK, et al. Promoter polymorphisms in the chromosome 5 gene cluster in asthma and atopy. Clin Exp Allergy 1995; 25 (Suppl 2): 74-8; discussion 95-6.
    • (1995) Clin Exp Allergy , vol.25 , Issue.SUPPL. 2 , pp. 74-78
    • Rosenwasser, L.J.1    Klemm, D.J.2    Dresback, J.K.3
  • 173
    • 0034034271 scopus 로고    scopus 로고
    • Polymorphism in the interleukin-4 promoter affects acquisition of human immunodeficiency virus type 1 syncytium-inducing phenotype
    • Nakayama EE, Hoshino Y, Xin X, et al. Polymorphism in the interleukin-4 promoter affects acquisition of human immunodeficiency virus type 1 syncytium-inducing phenotype. J Virol 2000; 74: 5452-9.
    • (2000) J Virol , vol.74 , pp. 5452-5459
    • Nakayama, E.E.1    Hoshino, Y.2    Xin, X.3
  • 174
    • 0032860665 scopus 로고    scopus 로고
    • Novel polymorphism in the 5'-untranslated region of the interleukin-4 gene
    • Takabayashi A, Ihara K, Sasaki Y, et al. Novel polymorphism in the 5'-untranslated region of the interleukin-4 gene. J Hum Genet 1999; 44: 352-3.
    • (1999) J Hum Genet , vol.44 , pp. 352-353
    • Takabayashi, A.1    Ihara, K.2    Sasaki, Y.3
  • 175
    • 17844402967 scopus 로고    scopus 로고
    • The -590C/T and -34C/T interleukin-4 promoter polymorphisms are not associated with atopic eczema in childhood
    • Elliott K, Fitzpatrick E, Hill D, et al. The -590C/T and -34C/T interleukin-4 promoter polymorphisms are not associated with atopic eczema in childhood. J Allergy Clin Immunol 2001; 108: 285-7.
    • (2001) J Allergy Clin Immunol , vol.108 , pp. 285-287
    • Elliott, K.1    Fitzpatrick, E.2    Hill, D.3
  • 176
    • 0037177450 scopus 로고    scopus 로고
    • The effect of IL4 +33C/T polymorphism on risk of Japanese sporadic Alzheimer's disease
    • Shibata N, Ohnuma T, Takahashi T, et al. The effect of IL4 +33C/T polymorphism on risk of Japanese sporadic Alzheimer's disease. Neurosci Lett 2002; 323: 161-3.
    • (2002) Neurosci Lett , vol.323 , pp. 161-163
    • Shibata, N.1    Ohnuma, T.2    Takahashi, T.3
  • 177
    • 0030910899 scopus 로고    scopus 로고
    • Mapping of the human IL10 gene and further characterization of the 5' flanking sequence
    • Eskdale J, Kube D, Tesch H, Gallagher G. Mapping of the human IL10 gene and further characterization of the 5' flanking sequence. Immunogenetics 1997; 46: 120-8.
    • (1997) Immunogenetics , vol.46 , pp. 120-128
    • Eskdale, J.1    Kube, D.2    Tesch, H.3    Gallagher, G.4
  • 178
    • 0032483014 scopus 로고    scopus 로고
    • Interleukin 10 secretion in relation to human IL-10 locus haplotypes
    • Eskdale J, Gallagher G, Verweij CL, et al. Interleukin 10 secretion in relation to human IL-10 locus haplotypes. Proc Natl Acad Sci USA 1998; 95: 9465-70.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9465-9470
    • Eskdale, J.1    Gallagher, G.2    Verweij, C.L.3
  • 179
    • 0036208781 scopus 로고    scopus 로고
    • The interleukin-10-1082 G/A polymorphism: Allele frequency in different populations and functional significance
    • Rees LE, Wood NA, Gillespie KM, et al. The interleukin-10-1082 G/A polymorphism: allele frequency in different populations and functional significance. Cell Mol Life Sci 2002; 59: 560-9.
    • (2002) Cell Mol Life Sci , vol.59 , pp. 560-569
    • Rees, L.E.1    Wood, N.A.2    Gillespie, K.M.3
  • 180
    • 0031017238 scopus 로고    scopus 로고
    • An investigation of polymorphism in the interleukin-10 gene promoter
    • Turner DM, Williams DM, Sankaran D, et al. An investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenet 1997; 24: 1-8.
    • (1997) Eur J Immunogenet , vol.24 , pp. 1-8
    • Turner, D.M.1    Williams, D.M.2    Sankaran, D.3
  • 181
    • 0033031984 scopus 로고    scopus 로고
    • Polymorphic haplotypes of the interleukin-10 5' flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis
    • Crawley E, Kay R, Sillibourne J, et al. Polymorphic haplotypes of the interleukin-10 5' flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis. Arthritis Rheum 1999; 42: 1101-8.
    • (1999) Arthritis Rheum , vol.42 , pp. 1101-1108
    • Crawley, E.1    Kay, R.2    Sillibourne, J.3
  • 182
    • 0032769836 scopus 로고    scopus 로고
    • Interleukin-10 promoter polymorphism predicts initial response of chronic hepatitis C to interferon alfa
    • Edwards-Smith CJ, Jonsson JR, Purdie DM, et al. Interleukin-10 promoter polymorphism predicts initial response of chronic hepatitis C to interferon alfa. Hepatology 1999; 30: 526-30.
    • (1999) Hepatology , vol.30 , pp. 526-530
    • Edwards-Smith, C.J.1    Jonsson, J.R.2    Purdie, D.M.3
  • 183
    • 0034139448 scopus 로고    scopus 로고
    • Cytokine (TNF alpha, LT alpha and IL-10) polymorphisms in inflammatory bowel diseases and normal controls: Differential effects on production and allele frequencies
    • Koss K, Satsangi J, Fanning GC, Welsh KI, Jewell DP. Cytokine (TNF alpha, LT alpha and IL-10) polymorphisms in inflammatory bowel diseases and normal controls: differential effects on production and allele frequencies. Genes Immun 2000; 1: 185-90.
    • (2000) Genes Immun , vol.1 , pp. 185-190
    • Koss, K.1    Satsangi, J.2    Fanning, G.C.3    Welsh, K.I.4    Jewell, D.P.5
  • 184
    • 2442430218 scopus 로고    scopus 로고
    • Renovascular disease is associated with low producer genotypes of the anti-inflammatory cytokine interleukin-10
    • George S, Ruan XZ, Navarrete C, et al. Renovascular disease is associated with low producer genotypes of the anti-inflammatory cytokine interleukin-10. Tissue Antigens 2004; 63: 470-5.
    • (2004) Tissue Antigens , vol.63 , pp. 470-475
    • George, S.1    Ruan, X.Z.2    Navarrete, C.3
  • 185
    • 8644291626 scopus 로고    scopus 로고
    • The A-1087IL-10 allele is associated with cardiovascular disease in SLE
    • Fei GZ, Svenungsson E, Frostegard J, Padyukov L. The A-1087IL-10 allele is associated with cardiovascular disease in SLE. Atherosclerosis 2004; 177: 409-14.
    • (2004) Atherosclerosis , vol.177 , pp. 409-414
    • Fei, G.Z.1    Svenungsson, E.2    Frostegard, J.3    Padyukov, L.4
  • 186
    • 0030704726 scopus 로고    scopus 로고
    • A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • Groux H, O'Garra A, Bigler M, et al. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997; 389: 737-42.
    • (1997) Nature , vol.389 , pp. 737-742
    • Groux, H.1    O'Garra, A.2    Bigler, M.3
  • 187
    • 4744371004 scopus 로고    scopus 로고
    • Increased expression of transforming growth factor-beta1 as a stabilizing factor in human atherosclerotic plaques
    • Cipollone F, Fazia M, Mincione G, et al. Increased expression of transforming growth factor-beta1 as a stabilizing factor in human atherosclerotic plaques. Stroke 2004; 35: 2253-7.
    • (2004) Stroke , vol.35 , pp. 2253-2257
    • Cipollone, F.1    Fazia, M.2    Mincione, G.3
  • 188
    • 0242366443 scopus 로고    scopus 로고
    • Transforming growth factor-beta: A neuroprotective factor in cerebral ischemia
    • Dhandapani KM, Brann DW. Transforming growth factor-beta: a neuroprotective factor in cerebral ischemia. Cell Biochem Biophys 2003; 39: 13-22.
    • (2003) Cell Biochem Biophys , vol.39 , pp. 13-22
    • Dhandapani, K.M.1    Brann, D.W.2
  • 189
    • 13144262796 scopus 로고    scopus 로고
    • Overexpression of transforming growth factor beta1 in arterial endothelium causes hyperplasia, apoptosis, and cartilaginous metaplasia
    • Schulick AH, Taylor AJ, Zuo W, et al. Overexpression of transforming growth factor beta1 in arterial endothelium causes hyperplasia, apoptosis, and cartilaginous metaplasia. Proc Natl Acad Sci USA 1998; 95: 6983-8.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6983-6988
    • Schulick, A.H.1    Taylor, A.J.2    Zuo, W.3
  • 190
    • 0034690805 scopus 로고    scopus 로고
    • Association of a T29 - >C polymorphism of the transforming growth factor-beta1 gene with genetic susceptibility to myocardial infarction in Japanese
    • Yokota M, Ichihara S, Lin TL, Nakashima N, Yamada Y. Association of a T29 - >C polymorphism of the transforming growth factor-beta1 gene with genetic susceptibility to myocardial infarction in Japanese. Circulation 2000; 101: 2783-7.
    • (2000) Circulation , vol.101 , pp. 2783-2787
    • Yokota, M.1    Ichihara, S.2    Lin, T.L.3    Nakashima, N.4    Yamada, Y.5
  • 191
    • 33750956065 scopus 로고    scopus 로고
    • The gene encoding transforming growth factor beta 1 confers risk of ischemic stroke and vascular dementia
    • Kim Y, Lee C. The gene encoding transforming growth factor beta 1 confers risk of ischemic stroke and vascular dementia. Stroke 2006; 37: 2843-5.
    • (2006) Stroke , vol.37 , pp. 2843-2845
    • Kim, Y.1    Lee, C.2
  • 192
    • 33750964898 scopus 로고    scopus 로고
    • TGF-beta 1 polymorphisms and risk of myocardial infarction and stroke: The Rotterdam Study
    • Sie MP, Uitterlinden AG, Bos MJ, et al. TGF-beta 1 polymorphisms and risk of myocardial infarction and stroke: the Rotterdam Study. Stroke 2006; 37: 2667-71.
    • (2006) Stroke , vol.37 , pp. 2667-2671
    • Sie, M.P.1    Uitterlinden, A.G.2    Bos, M.J.3
  • 193
    • 0032958714 scopus 로고    scopus 로고
    • Genetic control of the circulating concentration of transforming growth factor type beta1
    • Grainger DJ, Heathcote K, Chiano M, et al. Genetic control of the circulating concentration of transforming growth factor type beta1. Hum Mol Genet 1999; 8: 93-7.
    • (1999) Hum Mol Genet , vol.8 , pp. 93-97
    • Grainger, D.J.1    Heathcote, K.2    Chiano, M.3
  • 194
    • 0042831152 scopus 로고    scopus 로고
    • Editorial comment--How to search for the role of genetic polymorphisms in stroke: Theory vs practice
    • Di Napoli M. Editorial comment--How to search for the role of genetic polymorphisms in stroke: theory vs practice. Stroke 2003; 34: 1869-70.
    • (2003) Stroke , vol.34 , pp. 1869-1870
    • Di Napoli, M.1
  • 195
    • 33745453811 scopus 로고    scopus 로고
    • Aspects of the design and analysis of high-dimensional SNP studies for disease risk estimation
    • Prentice RL, Qi L. Aspects of the design and analysis of high-dimensional SNP studies for disease risk estimation. Biostatistics 2006; 7: 339-54.
    • (2006) Biostatistics , vol.7 , pp. 339-354
    • Prentice, R.L.1    Qi, L.2
  • 196
    • 0035170994 scopus 로고    scopus 로고
    • LDL immunization induces T-cell-dependent antibody formation and protection against atherosclerosis
    • Zhou X, Caligiuri G, Hamsten A, Lefvert AK, Hansson GK. LDL immunization induces T-cell-dependent antibody formation and protection against atherosclerosis. Arterioscler Thromb Vasc Biol 2001; 21: 108-14.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 108-114
    • Zhou, X.1    Caligiuri, G.2    Hamsten, A.3    Lefvert, A.K.4    Hansson, G.K.5
  • 197
    • 0038375997 scopus 로고    scopus 로고
    • Pneumococcal vaccination decreases atherosclerotic lesion formation: Molecular mimicry between Streptococcus pneumoniae and oxidized LDL
    • Binder CJ, Horkko S, Dewan A, et al. Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL. Nat Med 2003; 9: 736-43.
    • (2003) Nat Med , vol.9 , pp. 736-743
    • Binder, C.J.1    Horkko, S.2    Dewan, A.3
  • 198
    • 34247267297 scopus 로고    scopus 로고
    • Active and passive immunization for atherosclerosis
    • Chyu KY, Nilsson J, Shah PK. Active and passive immunization for atherosclerosis. Curr Opin Mol Ther 2007; 9: 176-82.
    • (2007) Curr Opin Mol Ther , vol.9 , pp. 176-182
    • Chyu, K.Y.1    Nilsson, J.2    Shah, P.K.3
  • 199
    • 34648849240 scopus 로고    scopus 로고
    • Immunomodulation of the inflammatory response in atherosclerosis
    • Kuiper J, van Puijvelde GH, van Wanrooij EJ, et al. Immunomodulation of the inflammatory response in atherosclerosis. Curr Opin Lipidol 2007; 18: 521-6.
    • (2007) Curr Opin Lipidol , vol.18 , pp. 521-526
    • Kuiper, J.1    van Puijvelde, G.H.2    van Wanrooij, E.J.3
  • 200
    • 0042376168 scopus 로고    scopus 로고
    • Statins and their role in vascular protection
    • Mason JC. Statins and their role in vascular protection. Clin Sci (Lond) 2003; 105: 251-66.
    • (2003) Clin Sci (Lond) , vol.105 , pp. 251-266
    • Mason, J.C.1
  • 201
    • 2642536741 scopus 로고    scopus 로고
    • Inflammation, immunity, and HMG-CoA reductase inhibitors: Statins as antiinflammatory agents?
    • Schonbeck U, Libby P. Inflammation, immunity, and HMG-CoA reductase inhibitors: statins as antiinflammatory agents? Circulation 2004; 109: 18-26.
    • (2004) Circulation , vol.109 , pp. 18-26
    • Schonbeck, U.1    Libby, P.2
  • 202
    • 0037038402 scopus 로고    scopus 로고
    • The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease
    • Youssef S, Stuve O, Patarroyo JC, et al. The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease. Nature 2002; 420: 78-84.
    • (2002) Nature , vol.420 , pp. 78-84
    • Youssef, S.1    Stuve, O.2    Patarroyo, J.C.3
  • 203
    • 3042573213 scopus 로고    scopus 로고
    • Benefits of statins in cerebrovascular disease
    • Di Napoli M. Benefits of statins in cerebrovascular disease. Curr Opin Investig Drugs 2004; 5: 295-305.
    • (2004) Curr Opin Investig Drugs , vol.5 , pp. 295-305
    • Di Napoli, M.1
  • 204
    • 1542284148 scopus 로고    scopus 로고
    • HMG CoA reductase inhibitors (statins): Use in stroke prevention and outcome after stroke
    • Moonis M, Fisher M. HMG CoA reductase inhibitors (statins): use in stroke prevention and outcome after stroke. Expert Rev Neurother 2004; 4: 241-7.
    • (2004) Expert Rev Neurother , vol.4 , pp. 241-247
    • Moonis, M.1    Fisher, M.2
  • 205
    • 9444249842 scopus 로고    scopus 로고
    • Statins in stroke prevention and carotid atherosclerosis: Systematic review and up-to-date meta-analysis
    • Amarenco P, Labreuche J, Lavallee P, Touboul PJ. Statins in stroke prevention and carotid atherosclerosis: systematic review and up-to-date meta-analysis. Stroke 2004; 35: 2902-9.
    • (2004) Stroke , vol.35 , pp. 2902-2909
    • Amarenco, P.1    Labreuche, J.2    Lavallee, P.3    Touboul, P.J.4
  • 207
    • 0035294675 scopus 로고    scopus 로고
    • Potential of anticytokine therapies in central nervous system ischaemia
    • Clark WM, Lutsep HL. Potential of anticytokine therapies in central nervous system ischaemia. Expert Opin Biol Ther 2001; 1: 227-37.
    • (2001) Expert Opin Biol Ther , vol.1 , pp. 227-237
    • Clark, W.M.1    Lutsep, H.L.2
  • 208
    • 0346366987 scopus 로고    scopus 로고
    • Nasal vaccination with myelin oligodendrocyte glycoprotein reduces stroke size by inducing IL-10-producing CD4+ T cells
    • Frenkel D, Huang Z, Maron R, et al. Nasal vaccination with myelin oligodendrocyte glycoprotein reduces stroke size by inducing IL-10-producing CD4+ T cells. J Immunol 2003; 171: 6549-55.
    • (2003) J Immunol , vol.171 , pp. 6549-6555
    • Frenkel, D.1    Huang, Z.2    Maron, R.3
  • 209
    • 0034785930 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha blockers in rheumatoid arthritis: Review of the clinical experience
    • Richard-Miceli C, Dougados M. Tumour necrosis factor-alpha blockers in rheumatoid arthritis: review of the clinical experience. BioDrugs 2001; 15: 251-9.
    • (2001) BioDrugs , vol.15 , pp. 251-259
    • Richard-Miceli, C.1    Dougados, M.2
  • 210
    • 26944485439 scopus 로고    scopus 로고
    • Infliximab: A review of its use in Crohn's disease and rheumatoid arthritis
    • Siddiqui MA, Scott LJ. Infliximab: a review of its use in Crohn's disease and rheumatoid arthritis. Drugs 2005; 65: 2179-208.
    • (2005) Drugs , vol.65 , pp. 2179-2208
    • Siddiqui, M.A.1    Scott, L.J.2
  • 211
    • 33646201107 scopus 로고    scopus 로고
    • TNF-alpha modulation for treatment of Alzheimer's disease: A 6-month pilot study
    • Tobinick E, Gross H, Weinberger A, Cohen H. TNF-alpha modulation for treatment of Alzheimer's disease: a 6-month pilot study. MedGenMed 2006; 8: 25.
    • (2006) MedGenMed , vol.8 , pp. 25
    • Tobinick, E.1    Gross, H.2    Weinberger, A.3    Cohen, H.4
  • 212
    • 0035940577 scopus 로고    scopus 로고
    • Use of anti-ICAM-1 therapy in ischemic stroke: results of the Enlimomab Acute Stroke Trial. Neurology 2001; 57: 1428-34.
    • Use of anti-ICAM-1 therapy in ischemic stroke: results of the Enlimomab Acute Stroke Trial. Neurology 2001; 57: 1428-34.


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