Increased amyloid β-peptide (1-40) level in brain of streptozotocin-induced diabetic rats

Neuroscience

Volumn 153, Issue 3, 2008, Pages 796-802

  Liu, Y ^a,b   Liu, H ^a   Yang, J ^c   Liu, X ^a   Lu, S ^a   Wen, T ^a   Xie, L ^a   Wang, G ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b XUZHOU MEDICAL UNIVERSITY   (China)

^c CERTARA UK LIMITED   (United Kingdom)

Author keywords

amyloid peptide; blood brain barrier; brain efflux; brain uptake; diabetes mellitus; P glycoprotein

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; CARBON 14; CYCLOSPORIN A; GLYCOPROTEIN P; INULIN; IODINE 125; VERAPAMIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN LEVEL; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HIPPOCAMPUS; IN VIVO STUDY; ISOTOPE LABELING; MALE; MEASUREMENT; NONHUMAN; PERMEABILITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; RAT; STREPTOZOCIN DIABETES; TEMPORAL CORTEX; TRANSPORT KINETICS;

EID: 43049106790     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2008.03.019     Document Type: Article

References (49)

1. Z. Arvanitakis R.S. Wilson J.L. Bienias D.A. Evans D.A. Bennett Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function Arch Neurol 61 2004 661 666
2. G.J. Biessels A. Kamal I.J. Urban B.M. Spruijt D.W. Erkelens W.H. Gispen Water maze learning and hippocampal synaptic plasticity in streptozotocin-diabetic rats: effects of insulin treatment Brain Res 800 1998 125 135
3. A.M. Brands G.J. Biessels E.H. de Haan L.J. Kappelle R.P. Kessels The effects of type 1 diabetes on cognitive performance: a meta-analysis Diabetes Care 28 2005 726 735
4. T. Brismar L. Maurex G. Cooray L. Juntti-Berggren P. Lindstrom K. Ekberg N. Adner S. Andersson Predictors of cognitive impairment in type 1 diabetes Psychoneuroendocrinology 32 2007 1041 1051
5. E. Carro I. Torres-Aleman The role of insulin and insulin-like growth factor I in the molecular and cellular mechanisms underlying the pathology of Alzheimer's disease Eur J Pharmacol 490 2004 127 133
6. J.R. Cirrito R. Deane A.M. Fagan M.L. Spinner M. Parsadanian M.B. Finn H. Jiang J.L. Prior A. Sagare K.R. Bales S.M. Paul B.V. Zlokovic D. Piwnica-Worms D.M. Holtzman P-glycoprotein deficiency at the blood-brain barrier increases amyloid-β deposition in an Alzheimer disease mouse model J Clin Invest 115 2005 3285 3290
7. R. Deane S. Du Yan R.K. Submamaryan B. LaRue S. Jovanovic E. Hogg D. Welch L. Manness C. Lin J. Yu H. Zhu J. Ghiso B. Frangione A. Stern A.M. Schmidt D.L. Armstrong B. Arnold B. Liliensiek P. Nawroth F. Hofman M. Kindy D. Stern B. Zlokovic RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain Nat Med 9 2003 907 913
8. J.M. Duarte J.P. Oses R.J. Rodrigues R.A. Cunha Modification of purinergic signaling in the hippocampus of streptozotocin-induced diabetic rats Neuroscience 149 2007 382 391
9. E.A. Eckman S.K. Adams F.J. Troendle B.A. Stodola M.A. Kahn A.H. Fauq H.D. Xiao K.E. Bernstein C.B. Eckman Regulation of steady-state β-amyloid levels in the brain by neprilysin and endothelin-converting enzyme but not angiotensin-converting enzyme J Biol Chem 281 2006 30471 30478
10. E.A. Eckman D.K. Reed C.B. Eckman Degradation of the Alzheimer's amyloid β-peptide by endothelin-converting enzyme J Biol Chem 276 2001 24540 24548
11. W. Farris S. Mansourian Y. Chang L. Lindsley E.A. Eckman M.P. Frosch C.B. Eckman R.E. Tanzi D.J. Selkoe S. Guenette Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain in vivo Proc Natl Acad Sci U S A 100 2003 4162 4167
12. S.C. Ferguson A. Blane P. Perros R.J. McCrimmon J.J. Best J. Wardlaw I.J. Deary B.M. Frier Cognitive ability and brain structure in type 1 diabetes: relation to microangiopathy and preceding severe hypoglycemia Diabetes 52 2003 149 156
13. L. Gasparini H. Xu Potential roles of insulin and IGF-1 in Alzheimer's disease Trends Neurosci 26 2003 404 406
14. M.J. Gillett R.N. Martins R.M. Clarnette S.A. Chubb D.G. Bruce B.B. Yeap Relationship between testosterone, sex hormone binding globulin and plasma amyloid β-peptide (1–40) in older men with subjective memory loss or dementia J Alzheimers Dis 5 2003 267 269
15. W.H. Gispen G.J. Biessels Cognition and synaptic plasticity in diabetes mellitus Trends Neurosci 23 2000 542 549
16. M.L. Hemming D.J. Selkoe Amyloid β-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor J Biol Chem 280 2005 37644 37650
17. J. Hu A. Igarashi M. Kamata H. Nakagawa Angiotensin-converting enzyme degrades Alzheimer amyloid β-peptide (Aβ) retards Aβ aggregation, deposition, fibril formation, and inhibits cytotoxicity J Biol Chem 276 2001 47863 47868
18. S. Ito S. Ohtsuki T. Terasaki Functional characterization of the brain-to-blood efflux clearance of human amyloid-β peptide (1–40) across the rat blood-brain barrier Neurosci Res 56 2006 246 252
19. N. Iwata S. Tsubuki Y. Takaki K. Shirotani B. Lu N.P. Gerard C. Gerard E. Hama H.J. Lee T.C. Saido Metabolic regulation of brain Aβ by neprilysin Science 292 2001 1550 1552
20. A.M. Jacobson G. Musen C.M. Ryan N. Silvers P. Cleary B. Waberski A. Burwood K. Weinger M. Bayless W. Dahms J. Harth Long-term effect of diabetes and its treatment on cognitive function N Engl J Med 356 2007 1842 1852
21. A. Kakee T. Terasaki Y. Sugiyama Brain efflux index as a novel method of analyzing efflux transport at the blood-brain barrier J Pharmacol Exp Ther 277 1996 1550 1559
22. J. Kamei S. Hirano S. Miyata A. Saitoh K. Onodera Effects of first- and second-generation histamine-H1-receptor antagonists on the pentobarbital-induced loss of the righting reflex in streptozotocin-induced diabetic mice J Pharmacol Sci 97 2005 266 272
23. K.K. Kandimalla G.L. Curran S.S. Holasek E.J. Gilles T.M. Wengenack J.F. Poduslo Pharmacokinetic analysis of the blood-brain barrier transport of 125I-amyloid β-protein 40 in wild-type and Alzheimer's disease transgenic mice (APP,PS1) and its implications for amyloid plaque formation J Pharmacol Exp Ther 313 2005 1370 1378
24. D. Kuhnke G. Jedlitschky M. Grube M. Krohn M. Jucker I. Mosyagin I. Cascorbi L.C. Walker H.K. Kroemer R.W. Warzok S. Vogelgesang MDR1-P-glycoprotein (ABCB1) mediates transport of Alzheimer's amyloid-β peptides: implications for the mechanisms of Aβ clearance at the blood-brain barrier Brain Pathol 17 2007 347 353
25. J.J. Kulstad P.S. Green D.G. Cook G.S. Watson M.A. Reger L.D. Baker S.R. Plymate S. Asthana K. Rhoads P.D. Mehta S. Craft Differential modulation of plasma β-amyloid by insulin in patients with Alzheimer disease Neurology 66 2006 1506 1510
26. F.C. Lam R. Liu P. Lu A.B. Shapiro J.M. Renoir F.J. Sharom P.B. Reiner β-Amyloid efflux mediated by P-glycoprotein J Neurochem 76 2001 1121 1128
27. Z.G. Li W. Zhang G. Grunberger A.A. Sima Hippocampal neuronal apoptosis in type 1 diabetes Brain Res 946 2002 221 231
28. Z.G. Li W. Zhang A.A. Sima The role of impaired insulin/IGF action in primary diabetic encephalopathy Brain Res 1037 2005 12 24
29. Z.G. Li W. Zhang A.A. Sima Alzheimer-like changes in rat models of spontaneous diabetes Diabetes 56 2007 1817 1824
30. H. Liu X. Xu Z. Yang Y. Deng X. Liu L. Xie Impaired function and expression of P-glycoprotein in blood-brain barrier of streptozotocin-induced diabetic rats Brain Res 1123 2006 245 252
31. H. Liu D. Zhang X. Xu X. Liu G. Wang L. Xie X. Pang L. Liu Attenuated function and expression of P-glycoprotein at blood-brain barrier and increased brain distribution of phenobarbital in streptozotocin-induced diabetic mice Eur J Pharmacol 561 2007 226 232
32. X.D. Liu G.Q. Liu P glycoprotein regulated transport of glutamate at blood brain barrier Acta Pharmacol Sin 22 2001 111 116
33. B.M. Lobnig O. Kromeke C. Optenhostert-Porst O.T. Wolf Hippocampal volume and cognitive performance in long-standing type 1 diabetic patients without macrovascular complications Diabet Med 23 2006 32 39
34. J.B. Mackic J. Bading J. Ghiso L. Walker T. Wisniewski B. Frangione B.V. Zlokovic Circulating amyloid-β peptide crosses the blood-brain barrier in aged monkeys and contributes to Alzheimer's disease lesions Vasc Pharmacol 38 2002 303 313
35. P.D. Mehta T. Pirttila B.A. Patrick M. Barshatzky S.P. Mehta Amyloid β-protein 1–40 and 1–42 levels in matched cerebrospinal fluid and plasma from patients with Alzheimer disease Neurosci Lett 304 2001 102 106
36. P.I. Moreira M.S. Santos C. Sena R. Seica C.R. Oliveira Insulin protects against amyloid β-peptide toxicity in brain mitochondria of diabetic rats Neurobiol Dis 18 2005 628 637
37. R. Oba A. Igarashi M. Kamata K. Nagata S. Takano H. Nakagawa The N-terminal active centre of human angiotensin-converting enzyme degrades Alzheimer amyloid β-peptide Eur J Neurosci 21 2005 733 740
38. A. Ott R.P. Stolk F. van Harskamp H.A. Pols A. Hofman M.M. Breteler Diabetes mellitus and the risk of dementia: The Rotterdam Study Neurology 53 1999 1937 1942
39. W. Pan B. Solomon L.M. Maness A.J. Kastin Antibodies to β-amyloid decrease the blood-to-brain transfer of β-amyloid peptide Exp Biol Med (Maywood) 227 2002 609 615
40. W.Q. Qiu D.M. Walsh Z. Ye K. Vekrellis J. Zhang M.B. Podlisny M.R. Rosner A. Safavi L.B. Hersh D.J. Selkoe Insulin-degrading enzyme regulates extracellular levels of amyloid β-protein by degradation J Biol Chem 273 1998 32730 32738
41. D.J. Selkoe Toward a comprehensive theory for Alzheimer's disease Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid β-protein Ann N Y Acad Sci 924 2000 17 25
42. M. Shibata S. Yamada S.R. Kumar M. Calero J. Bading B. Frangione D.M. Holtzman C.A. Miller D.K. Strickland J. Ghiso B.V. Zlokovic Clearance of Alzheimer's amyloid-β (1–40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier J Clin Invest 106 2000 1489 1499
43. T. Shiiki S. Ohtsuki A. Kurihara H. Naganuma K. Nishimura M. Tachikawa K. Hosoya T. Terasaki Brain insulin impairs amyloid-β (1–40) clearance from the brain J Neurosci 24 2004 9632 9637
44. C. Tamaki S. Ohtsuki T. Iwatsubo T. Hashimoto K. Yamada C. Yabuki T. Terasaki Major involvement of low-density lipoprotein receptor-related protein 1 in the clearance of plasma free amyloid β-peptide by the liver Pharm Res 23 2006 1407 1416
45. C. Tamaki S. Ohtsuki T. Terasaki Insulin facilitates the hepatic clearance of plasma amyloid β-peptide (1–40) by intracellular translocation of low-density lipoprotein receptor-related protein 1 (LRP1) to the plasma membrane in hepatocytes Mol Pharmacol 72 2007 850 855
46. S. Vogelgesang I. Cascorbi E. Schroeder J. Pahnke H.K. Kroemer W. Siegmund C. Kunert-Keil L.C. Walker R.W. Warzok Deposition of Alzheimer's β-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans Pharmacogenetics 12 2002 535 541
47. A.M. Wessels S.A. Rombouts P.L. Remijnse Y. Boom P. Scheltens F. Barkhof R.J. Heine F.J. Snoek Cognitive performance in type 1 diabetes patients is associated with cerebral white matter volume Diabetologia 50 2007 1763 1769
48. K. Yasojima E.G. McGeer P.L. McGeer Relationship between β amyloid peptide generating molecules and neprilysin in Alzheimer disease and normal brain Brain Res 919 2001 115 121
49. B.V. Zlokovic C.L. Martel E. Matsubara J.G. McComb G. Zheng R.T. McCluskey B. Frangione J. Ghiso Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid β at the blood-brain and blood-cerebrospinal fluid barriers Proc Natl Acad Sci U S A 93 1996 4229 4234