메뉴 건너뛰기




Volumn 277, Issue 3, 1996, Pages 1550-1559

Brain efflux index as a novel method of analyzing efflux transport at the blood-brain barrier

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLGLUCOSE; 4 (2 HYDROXYETHYL) 1 PIPERAZINEETHANESULFONIC ACID; BUTANOL; INULIN; KETAMINE; LEVO GLUCOSE; MANNITOL; PHLORIZIN; WATER; XYLAZINE;

EID: 0030426820     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (222)

References (47)
  • 1
    • 0028299479 scopus 로고
    • Contribution of probenecid-sensitive anion transport processes at the brain capillary endothelium and choroid plexus to the efficient efflux of valproic acid from the central nervous system
    • ADKISON, K. D. K., ARTRU, A. A., POWERS, K. M. AND SHEN, D. D.: Contribution of probenecid-sensitive anion transport processes at the brain capillary endothelium and choroid plexus to the efficient efflux of valproic acid from the central nervous system. J. Pharmacol. Exp. Ther. 268: 797-805, 1994.
    • (1994) J. Pharmacol. Exp. Ther. , vol.268 , pp. 797-805
    • Adkison, K.D.K.1    Artru, A.A.2    Powers, K.M.3    Shen, D.D.4
  • 2
    • 0027184484 scopus 로고
    • 2 (Tyr-W-MIF-1) is transported from the brain to the blood by peptide transport system-1
    • 2 (Tyr-W-MIF-1) is transported from the brain to the blood by peptide transport system-1. J. Neurosci. Res. 35: 690-695, 1993.
    • (1993) J. Neurosci. Res. , vol.35 , pp. 690-695
    • Banks, W.A.1    Kastin, A.J.2    Ehrensing, C.A.3
  • 3
    • 0026040784 scopus 로고
    • Bidirectional saturable transport of LHRH across the blood-brain barrier
    • BARRERA, C. M., KASTIN, A. J., FASOLD, M. B. AND BANKS, W. A.: Bidirectional saturable transport of LHRH across the blood-brain barrier. Am. J. Physiol. 261: E312-E318, 1991.
    • (1991) Am. J. Physiol. , vol.261
    • Barrera, C.M.1    Kastin, A.J.2    Fasold, M.B.3    Banks, W.A.4
  • 5
    • 0018080931 scopus 로고
    • Polarity of the blood-brain barrier: Neutral amino acid transport into isolated brain capillaries
    • BETZ, A. L. AND GOLDSTEIN, G. W.: Polarity of the blood-brain barrier: Neutral amino acid transport into isolated brain capillaries. Science 202: 225-227, 1978.
    • (1978) Science , vol.202 , pp. 225-227
    • Betz, A.L.1    Goldstein, G.W.2
  • 6
    • 0018402408 scopus 로고
    • Hexose transport and phosphorylation by capillaries isolated from rat brain
    • BETZ, A. L., CSEJTEY, J. AND GOLDSTEIN, G. W.: Hexose transport and phosphorylation by capillaries isolated from rat brain. Am. J. Physiol. 236: C96-C102, 1979.
    • (1979) Am. J. Physiol. , vol.236
    • Betz, A.L.1    Csejtey, J.2    Goldstein, G.W.3
  • 7
    • 0016816050 scopus 로고
    • Intrathecal chemotherapy: Brain tissue profiles after ventriculocisternal perfusion
    • BLASBERG, R. G., PATLAK, C. AND FENSTERMACHER, J. D.: Intrathecal chemotherapy: Brain tissue profiles after ventriculocisternal perfusion. J. Pharmacol. Exp. Ther. 195: 73-83, 1975.
    • (1975) J. Pharmacol. Exp. Ther. , vol.195 , pp. 73-83
    • Blasberg, R.G.1    Patlak, C.2    Fenstermacher, J.D.3
  • 8
    • 0001253552 scopus 로고
    • Molecular cloning of the bovine blood-brain barrier glucose transporter cDNA and demonstration of phylogenetic conservation of the 5′-untranslated region
    • BOADO, R. J. AND PARDRIDGE, W. M.: Molecular cloning of the bovine blood-brain barrier glucose transporter cDNA and demonstration of phylogenetic conservation of the 5′-untranslated region. Mol. Cell Neurosci. 1: 224-232, 1990.
    • (1990) Mol. Cell Neurosci. , vol.1 , pp. 224-232
    • Boado, R.J.1    Pardridge, W.M.2
  • 9
    • 0027280530 scopus 로고
    • Glucose deprivation causes posttranscriptional enhancement of brain capillary endothelial glucose transporter gene expression via GLUT1 mRNA stabilization
    • BOADO, R. J. AND PARDRIDGE, W. M.: Glucose deprivation causes posttranscriptional enhancement of brain capillary endothelial glucose transporter gene expression via GLUT1 mRNA stabilization. J Neurochem. 60: 2290-2296, 1993.
    • (1993) J Neurochem. , vol.60 , pp. 2290-2296
    • Boado, R.J.1    Pardridge, W.M.2
  • 10
    • 0028240140 scopus 로고
    • Measurement of blood-brain barrier GLUT1 glucose transporter and actin mRNA by a quantitative polymerase chain reaction assay
    • BOADO, R. J. AND PAHDRIDGE, W. M. Measurement of blood-brain barrier GLUT1 glucose transporter and actin mRNA by a quantitative polymerase chain reaction assay. J. Neurochem. 62: 2085-2090, 1994.
    • (1994) J. Neurochem. , vol.62 , pp. 2085-2090
    • Boado, R.J.1    Pahdridge, W.M.2
  • 11
    • 0027979905 scopus 로고
    • Enhanced expression of the blood-brain barrier GLUT1 glucose transporter gene by brain-derived factors
    • BOADO, R. J., WANG, L. AND PARDRIDCE, W. M.: Enhanced expression of the blood-brain barrier GLUT1 glucose transporter gene by brain-derived factors. Mol. Brain Res. 22: 259-267, 1994.
    • (1994) Mol. Brain Res. , vol.22 , pp. 259-267
    • Boado, R.J.1    Wang, L.2    Pardridce, W.M.3
  • 12
    • 0022000224 scopus 로고
    • Kinetics of regional blood-brain barrier glucose transport and cerebral blood flow determined with the carotid injection technique in conscious rats
    • BRAUN, L. D., MILLER, L. P., PARDRIDGE, W. M. AND OLDENDORF, W. H.: Kinetics of regional blood-brain barrier glucose transport and cerebral blood flow determined with the carotid injection technique in conscious rats. J. Neurochem. 44: 911-915, 1985.
    • (1985) J. Neurochem. , vol.44 , pp. 911-915
    • Braun, L.D.1    Miller, L.P.2    Pardridge, W.M.3    Oldendorf, W.H.4
  • 13
    • 0021794208 scopus 로고
    • The blood-brain barrier, a dynamic regulatory interface
    • CORNFORD, E. M.: The blood-brain barrier, a dynamic regulatory interface. Mol. Physiol. 7: 219-260, 1985.
    • (1985) Mol. Physiol. , vol.7 , pp. 219-260
    • Cornford, E.M.1
  • 14
    • 0021807216 scopus 로고
    • Blood-brain barrier transport of valproic acid
    • CORNFORD, E. M., DIEP, C. P. AND PARDRIDGE, W. M.: Blood-brain barrier transport of valproic acid. J. Neurochem. 44: 1541-1550, 1985.
    • (1985) J. Neurochem. , vol.44 , pp. 1541-1550
    • Cornford, E.M.1    Diep, C.P.2    Pardridge, W.M.3
  • 15
    • 0016284260 scopus 로고
    • Bulk flow of interstitial fluid after intracranial injection of blue dextran 2000
    • CSERR, H. F. AND OSTRACH L. H.: Bulk flow of interstitial fluid after intracranial injection of blue dextran 2000. Exp. Neurol. 45: 50-60, 1974.
    • (1974) Exp. Neurol. , vol.45 , pp. 50-60
    • Cserr, H.F.1    Ostrach, L.H.2
  • 16
    • 0018025773 scopus 로고
    • Iodide and thiocyanate efflux from brain following injection into rat caudate nucleus
    • CSERR, H. F. AND BERMAN, B. J.: Iodide and thiocyanate efflux from brain following injection into rat caudate nucleus. Am. J. Physiol. 235: F331-F337, 1978.
    • (1978) Am. J. Physiol. , vol.235
    • Cserr, H.F.1    Berman, B.J.2
  • 17
    • 0026002719 scopus 로고
    • Muscle microdialysis as a model study to relate the drug concentration in tissue intersitital fluid and dialysate
    • DEGUCHI, Y., TERASAKI, T., KAWASAKI, S. AND TSUJI, A.: Muscle microdialysis as a model study to relate the drug concentration in tissue intersitital fluid and dialysate. J. Pharmacobio-dyn. 14: 483-492, 1991.
    • (1991) J. Pharmacobio-dyn. , vol.14 , pp. 483-492
    • Deguchi, Y.1    Terasaki, T.2    Kawasaki, S.3    Tsuji, A.4
  • 18
    • 0023553388 scopus 로고
    • Probenecid-induced accumulation of 5-hydroxyindoleacetic acid and homovanillic acid in rat brain
    • EMANUELSSON, B.-M., PAALZOW, L. AND SUNZEL, M.: Probenecid-induced accumulation of 5-hydroxyindoleacetic acid and homovanillic acid in rat brain. J. Pharm. Pharmacol. 39: 705-710, 1987.
    • (1987) J. Pharm. Pharmacol. , vol.39 , pp. 705-710
    • Emanuelsson, B.-M.1    Paalzow, L.2    Sunzel, M.3
  • 19
    • 0019783061 scopus 로고
    • Methods for quantifying the transport of drugs across brain barrier systems
    • FENSTERMACHER, J., BLASBERG, R. AND PATLAK, C.: Methods for quantifying the transport of drugs across brain barrier systems. Pharmacol. Ther. 14: 217-248, 1981.
    • (1981) Pharmacol. Ther. , vol.14 , pp. 217-248
    • Fenstermacher, J.1    Blasberg, R.2    Patlak, C.3
  • 20
    • 0023731412 scopus 로고
    • Drug "Diffusion" within the brain
    • FENSTERMACHER, J. AND KAYE, T.: Drug "Diffusion" within the brain. Ann. NY Acad. Sci. 531: 29-39, 1988.
    • (1988) Ann. NY Acad. Sci. , vol.531 , pp. 29-39
    • Fenstermacher, J.1    Kaye, T.2
  • 21
    • 0344144082 scopus 로고
    • The brain barrier system. III: The efflux of intracerebrally administered amino acids from the brain
    • LAJTHA, A. AND TOTH, J.: The brain barrier system. III: The efflux of intracerebrally administered amino acids from the brain. J. Neurochem. 9: 199-212, 1962.
    • (1962) J. Neurochem. , vol.9 , pp. 199-212
    • Lajtha, A.1    Toth, J.2
  • 22
    • 0025980945 scopus 로고
    • In vivo study of the elimination from rat brain of an intracerebrally formed xenobiotic metabolite, 1-naphthyl-β-D-glucuronide
    • LEININGER, B., GHERSI-EGEA, J. F., SIEST, G. AND MINN, A.: In vivo study of the elimination from rat brain of an intracerebrally formed xenobiotic metabolite, 1-naphthyl-β-D-glucuronide. J. Neurochem. 56: 1163-1168, 1991.
    • (1991) J. Neurochem. , vol.56 , pp. 1163-1168
    • Leininger, B.1    Ghersi-Egea, J.F.2    Siest, G.3    Minn, A.4
  • 25
    • 0014888279 scopus 로고
    • Measurement of brain uptake of radiolabeled substances using a tritiated water internal standard
    • OLDENDORF, W. H.: Measurement of brain uptake of radiolabeled substances using a tritiated water internal standard. Brain Res. 24: 372-376, 1970.
    • (1970) Brain Res. , vol.24 , pp. 372-376
    • Oldendorf, W.H.1
  • 26
    • 0020325558 scopus 로고
    • Measurement of cerebral glucose utilization using washout after carotid injection in the rat
    • OLDENDORF, W. H., PARDRIDGE, W. M., BRAUN, L. D. AND CRANE, P. D.: Measurement of cerebral glucose utilization using washout after carotid injection in the rat. J. Neurochem. 38: 1413-1418, 1982.
    • (1982) J. Neurochem. , vol.38 , pp. 1413-1418
    • Oldendorf, W.H.1    Pardridge, W.M.2    Braun, L.D.3    Crane, P.D.4
  • 27
    • 0017600519 scopus 로고
    • Transport of metabolic substrates through the blood-brain barrier
    • PARDRIDGE, W. M. AND OLDENDORF, W. H.: Transport of metabolic substrates through the blood-brain barrier. J. Neurochem. 28: 5-12, 1977.
    • (1977) J. Neurochem. , vol.28 , pp. 5-12
    • Pardridge, W.M.1    Oldendorf, W.H.2
  • 28
    • 0021020420 scopus 로고
    • Brain metabolism: A perspective from the blood-brain barrier
    • PARDRIDGE, W. M.: Brain metabolism: A perspective from the blood-brain barrier. Physiol. Rev. 63: 1481-1535, 1983.
    • (1983) Physiol. Rev. , vol.63 , pp. 1481-1535
    • Pardridge, W.M.1
  • 29
    • 0022003372 scopus 로고
    • Blood-brain barrier transport of butanol and water relative to N-isopropyl-p-iodoamphetamine as the internal reference
    • PARDRIDGE, W. M. AND FIERER, G.: Blood-brain barrier transport of butanol and water relative to N-isopropyl-p-iodoamphetamine as the internal reference. J. Cereb. Blood Flow Metab. 5: 275-281, 1985.
    • (1985) J. Cereb. Blood Flow Metab. , vol.5 , pp. 275-281
    • Pardridge, W.M.1    Fierer, G.2
  • 30
    • 0025223675 scopus 로고
    • Evaluation of cationized rat albumin as a potential blood-brain barrier drug transport vector
    • PARDRIDGE, W. M., TRIGUERO, D., BUCIAK, J. AND YANG, J.: Evaluation of cationized rat albumin as a potential blood-brain barrier drug transport vector. J. Pharmacol. Exp. Ther. 255: 893-899, 1990.
    • (1990) J. Pharmacol. Exp. Ther. , vol.255 , pp. 893-899
    • Pardridge, W.M.1    Triguero, D.2    Buciak, J.3    Yang, J.4
  • 32
    • 0023634699 scopus 로고
    • Kinetics of neutral amino acid transport across the blood-brain barrier
    • SMITH, Q. R., MOMMA, S., AOYAGI, M. AND RAPOPORT, S. I.: Kinetics of neutral amino acid transport across the blood-brain barrier. J. Neurochem. 49: 1651-1658, 1987.
    • (1987) J. Neurochem. , vol.49 , pp. 1651-1658
    • Smith, Q.R.1    Momma, S.2    Aoyagi, M.3    Rapoport, S.I.4
  • 33
    • 0021918465 scopus 로고
    • Saturable transport of cimetidine from cerebrospinal fluid to blood in rats
    • SUZUKI, H., SAWADA, Y., SUGIYAMA, Y., IGA, T. AND HANANO, M.: Saturable transport of cimetidine from cerebrospinal fluid to blood in rats. J. Pharmacobio-dyn. 8: 73-76, 1985.
    • (1985) J. Pharmacobio-dyn. , vol.8 , pp. 73-76
    • Suzuki, H.1    Sawada, Y.2    Sugiyama, Y.3    Iga, T.4    Hanano, M.5
  • 35
    • 0023572367 scopus 로고
    • Anion exchanger mediates benzylpenicillin transport in rat choroid plexus
    • SUZUKI, H., SAWADA, Y., SUGIYAMA, Y., IGA, T. AND HANANO, M.: Anion exchanger mediates benzylpenicillin transport in rat choroid plexus. J. Pharmacol. Exp. Ther. 243: 1147-1152, 1987b.
    • (1987) J. Pharmacol. Exp. Ther. , vol.243 , pp. 1147-1152
    • Suzuki, H.1    Sawada, Y.2    Sugiyama, Y.3    Iga, T.4    Hanano, M.5
  • 36
    • 0026293045 scopus 로고
    • Blood-brain barrier: Transport studies in isolated brain capillaries and in cultured brain endothelial cells
    • TAKAKURA, Y., AUDUS, K. L. AND BORCHARDT, R. T.: Blood-brain barrier: Transport studies in isolated brain capillaries and in cultured brain endothelial cells. Adv. Pharmacol. 22: 137-165, 1991a.
    • (1991) Adv. Pharmacol. , vol.22 , pp. 137-165
    • Takakura, Y.1    Audus, K.L.2    Borchardt, R.T.3
  • 37
    • 0025935897 scopus 로고
    • Hexose uptake in primary cultures of bovine brain microvessel endothelial cells. I. Basic characteristics and effects of D-glucose and insulin
    • TAKAKURA, Y., KUENTZEL, S. L., RAUB, T. J., DAVIES, A., BALDWIN, S. A. AND BORCHARDT, R. T.: Hexose uptake in primary cultures of bovine brain microvessel endothelial cells. I. Basic characteristics and effects of D-glucose and insulin. Biochim. Biophys. Acta 1070: 1-10, 1991b.
    • (1991) Biochim. Biophys. Acta , vol.1070 , pp. 1-10
    • Takakura, Y.1    Kuentzel, S.L.2    Raub, T.J.3    Davies, A.4    Baldwin, S.A.5    Borchardt, R.T.6
  • 38
    • 0026669192 scopus 로고
    • Functional involvement of P-glycoprotein in blood-brain barrier
    • TATSUTA, T., NAITO, M., OH-HARA, T., SUGAWARA, I. AND TSURUO, T.: Functional involvement of P-glycoprotein in blood-brain barrier. J. Biol. Chem. 267: 20383-20391, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 20383-20391
    • Tatsuta, T.1    Naito, M.2    Oh-Hara, T.3    Sugawara, I.4    Tsuruo, T.5
  • 39
    • 0022873824 scopus 로고
    • Differential effect of plasma protein binding of bupivacaine on its in vivo transfer into the brain and salivary gland of rats
    • TERASAKI, T., PABDRIDGE, W. M. AND DENSON, D. D.: Differential effect of plasma protein binding of bupivacaine on its in vivo transfer into the brain and salivary gland of rats. J. Pharmacol. Exp. Ther. 239: 724-729, 1986.
    • (1986) J. Pharmacol. Exp. Ther. , vol.239 , pp. 724-729
    • Terasaki, T.1    Pabdridge, W.M.2    Denson, D.D.3
  • 40
    • 0025989302 scopus 로고
    • Transport of monocarboxylic acids at the blood-brain barrier: Studies with monolayers of primary cultured bovine brain capillary endothelial cells
    • TERASAKI, T., TAKAKUWA, S., MORITANI, S. AND TSUJI, A.: Transport of monocarboxylic acids at the blood-brain barrier: Studies with monolayers of primary cultured bovine brain capillary endothelial cells. J. Pharmacol. Exp. Ther. 258: 932-937, 1991.
    • (1991) J. Pharmacol. Exp. Ther. , vol.258 , pp. 932-937
    • Terasaki, T.1    Takakuwa, S.2    Moritani, S.3    Tsuji, A.4
  • 42
    • 0027290876 scopus 로고
    • Restricted transport of cyclosporin A across the blood-brain barrier by a multidrug transporter, P-glycoprotein
    • TSUJI, A., TAMAI, I., SAKATA, A., TENDA, Y. AND TERASAKI, T.: Restricted transport of cyclosporin A across the blood-brain barrier by a multidrug transporter, P-glycoprotein. Biochem. Pharmacol. 48: 1096-1099, 1993.
    • (1993) Biochem. Pharmacol. , vol.48 , pp. 1096-1099
    • Tsuji, A.1    Tamai, I.2    Sakata, A.3    Tenda, Y.4    Terasaki, T.5
  • 43
    • 0029013672 scopus 로고
    • Zidovudine transport in the rabbit brain during intravenous and intracerebroventricular infusion
    • WANG, Y. AND SAWCHUK, R. J.: Zidovudine transport in the rabbit brain during intravenous and intracerebroventricular infusion. J. Pharm. Res. 84: 871-876, 1995.
    • (1995) J. Pharm. Res. , vol.84 , pp. 871-876
    • Wang, Y.1    Sawchuk, R.J.2
  • 44
    • 0024673048 scopus 로고
    • cDNA cloning and sequence analysis of the glucose transporter from porcine blood-brain barrier
    • WEILER-GUTTLER, H., ZINKE, H., MOCKEL, B., FREY, A. AND GASSEN, H. G.: cDNA cloning and sequence analysis of the glucose transporter from porcine blood-brain barrier. Biol. Chem. Hoppe-Seyler 370: 467-473, 1989.
    • (1989) Biol. Chem. Hoppe-Seyler , vol.370 , pp. 467-473
    • Weiler-Guttler, H.1    Zinke, H.2    Mockel, B.3    Frey, A.4    Gassen, H.G.5
  • 45
    • 0027769788 scopus 로고
    • Distributional transport kinetics of zidovudine between plasma and brain extracellular fluid/ cerebrospinal fluid in the rabbit: Investigation of the inhibitory effect of probenecid utilizing microdialysis
    • WONG, S. L., VAN BELLE, K. AND SAWCHUK, R. J.: Distributional transport kinetics of zidovudine between plasma and brain extracellular fluid/ cerebrospinal fluid in the rabbit: Investigation of the inhibitory effect of probenecid utilizing microdialysis. J. Pharmacol. Exp. Ther. 264: 899-909, 1993.
    • (1993) J. Pharmacol. Exp. Ther. , vol.264 , pp. 899-909
    • Wong, S.L.1    Van Belle, K.2    Sawchuk, R.J.3
  • 46
    • 0019854279 scopus 로고
    • A pharmacokinetic analysis program (MULTI) for microcomputer
    • YAMAOKA, K., TANIGAWARA, Y., NAKAGAWA, T. AND UNO, T.: A pharmacokinetic analysis program (MULTI) for microcomputer. J. Pharmacobio-dyn. 4: 879-885, 1981.
    • (1981) J. Pharmacobio-dyn. , vol.4 , pp. 879-885
    • Yamaoka, K.1    Tanigawara, Y.2    Nakagawa, T.3    Uno, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.