-
1
-
-
0037372571
-
P-glycoprotein limits the brain penetration of nonsedating but not sedating H1-antagonists
-
Chen C, Hanson E, Watson JW, Lee JS. P-glycoprotein limits the brain penetration of nonsedating but not sedating H1-antagonists. Drug Metab Dispos. 2003;31:312-318.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 312-318
-
-
Chen, C.1
Hanson, E.2
Watson, J.W.3
Lee, J.S.4
-
2
-
-
0025918361
-
Sedation and histamine H1-receptor antagonism: Studies in man with the enantiomers of chlorpheniramine and dimethindene
-
Nicholson AN, Pascoe PA, Turner C, Ganellin CR, Greengrass PM, Casy AF, et al. Sedation and histamine H1-receptor antagonism: studies in man with the enantiomers of chlorpheniramine and dimethindene. Br J Pharmacol. 1991;104:270-276.
-
(1991)
Br J Pharmacol
, vol.104
, pp. 270-276
-
-
Nicholson, A.N.1
Pascoe, P.A.2
Turner, C.3
Ganellin, C.R.4
Greengrass, P.M.5
Casy, A.F.6
-
3
-
-
0028343237
-
Neuropharmacology of the histaminergic neuron system in the brain and its relationship with behavioral disorders
-
Onodera K, Yamatodani A, Watanabe T, Wada H. Neuropharmacology of the histaminergic neuron system in the brain and its relationship with behavioral disorders. Prog Neurobiol. 1994;42:685-702.
-
(1994)
Prog Neurobiol
, vol.42
, pp. 685-702
-
-
Onodera, K.1
Yamatodani, A.2
Watanabe, T.3
Wada, H.4
-
4
-
-
0032784774
-
Histamine and the antiallergic antihistamines: A history of their discoveries
-
Emanuel MB. Histamine and the antiallergic antihistamines: a history of their discoveries. Clin Exp Allergy. 1999;29:1-11.
-
(1999)
Clin Exp Allergy
, vol.29
, pp. 1-11
-
-
Emanuel, M.B.1
-
5
-
-
0034888307
-
Affinity for the P-glycoprotein efflux pump at the blood-brain barrier may explain the lack of CNS side-effects of modern antihistamines
-
Chishty M, Reichel A, Siva J, Abbott NJ, Begley DJ. Affinity for the P-glycoprotein efflux pump at the blood-brain barrier may explain the lack of CNS side-effects of modern antihistamines. J Drug Target. 2001;9:223-228.
-
(2001)
J Drug Target
, vol.9
, pp. 223-228
-
-
Chishty, M.1
Reichel, A.2
Siva, J.3
Abbott, N.J.4
Begley, D.J.5
-
8
-
-
0037237882
-
Effect of diabetes on the blood brain barrier
-
Horani MH, Mooradian AD. Effect of diabetes on the blood brain barrier. Curr Pharm Des. 2003;9:833-840.
-
(2003)
Curr Pharm des
, vol.9
, pp. 833-840
-
-
Horani, M.H.1
Mooradian, A.D.2
-
10
-
-
0021404067
-
In vivo and electron microscopic study of the development of cerebral diabetic microangiography
-
McCuskey PA, McCuskey RS. In vivo and electron microscopic study of the development of cerebral diabetic microangiography. Microcirc Endothelium Lymphatics. 1984;1:221-244.
-
(1984)
Microcirc Endothelium Lymphatics
, vol.1
, pp. 221-244
-
-
McCuskey, P.A.1
McCuskey, R.S.2
-
11
-
-
0021933130
-
Basement membrane of hypothalamus and cortex capillaries from normotensive and spontaneously hypertensive rats with streptozotocin-induced diabetes
-
Junker U, Jaggi C, Bestetti G, Rossi GL. Basement membrane of hypothalamus and cortex capillaries from normotensive and spontaneously hypertensive rats with streptozotocin-induced diabetes. Acta Neuropathol. 1985;65:202-208.
-
(1985)
Acta Neuropathol
, vol.65
, pp. 202-208
-
-
Junker, U.1
Jaggi, C.2
Bestetti, G.3
Rossi, G.L.4
-
12
-
-
0023574767
-
Quantitative changes of cerebral neocortical structure in insulin-treated long-term streptozocin-induced diabetes in rats
-
Jakobsen J, Sidenius P, Gundersen HJ, Osterby R. Quantitative changes of cerebral neocortical structure in insulin-treated long-term streptozocin-induced diabetes in rats. Diabetes. 1987; 36:597-601.
-
(1987)
Diabetes
, vol.36
, pp. 597-601
-
-
Jakobsen, J.1
Sidenius, P.2
Gundersen, H.J.3
Osterby, R.4
-
13
-
-
0027167904
-
Cerebral circulation during diabetes mellitus
-
Mayhan WG. Cerebral circulation during diabetes mellitus. Pharmacol Ther. 1993;57:377-391.
-
(1993)
Pharmacol Ther
, vol.57
, pp. 377-391
-
-
Mayhan, W.G.1
-
14
-
-
0019492103
-
Selective extravascular escape of albumin into the cerebral cortex of the diabetic rat
-
Stauber WT, Ong SH, McCuskey RS. Selective extravascular escape of albumin into the cerebral cortex of the diabetic rat. Diabetes. 1981;30:500-503.
-
(1981)
Diabetes
, vol.30
, pp. 500-503
-
-
Stauber, W.T.1
Ong, S.H.2
McCuskey, R.S.3
-
15
-
-
0033526176
-
P-glycoprotein, a gatekeeper in the blood-brain barrier
-
Schinkel AH. P-glycoprotein, a gatekeeper in the blood-brain barrier. Adv Drug Deliv Rev. 1999;36:179-194.
-
(1999)
Adv Drug Deliv Rev
, vol.36
, pp. 179-194
-
-
Schinkel, A.H.1
-
16
-
-
0034452788
-
Blood-brain barrier transport of H1-antagonist ebastine and its metabolite carebastine
-
Tamai I, Kido Y, Yamashita J, Sai Y, Tsuji A. Blood-brain barrier transport of H1-antagonist ebastine and its metabolite carebastine. J Drug Target. 2000;8:383-393.
-
(2000)
J Drug Target
, vol.8
, pp. 383-393
-
-
Tamai, I.1
Kido, Y.2
Yamashita, J.3
Sai, Y.4
Tsuji, A.5
-
17
-
-
0141507948
-
P-glycoprotein influences the brain concentrations of cetirizine (Zyrtec), a second-generation non-sedating antihistamine
-
Polli JW, Baughman TM, Humphreys JE, Jordan KH, Mote AL, Salisbury JA, et al. P-glycoprotein influences the brain concentrations of cetirizine (Zyrtec), a second-generation non-sedating antihistamine. J Pharm Sci. 2003;92:2082-2089.
-
(2003)
J Pharm Sci
, vol.92
, pp. 2082-2089
-
-
Polli, J.W.1
Baughman, T.M.2
Humphreys, J.E.3
Jordan, K.H.4
Mote, A.L.5
Salisbury, J.A.6
-
18
-
-
0036086885
-
Differential effects of streptozotocin-induced diabetes on expression of hepatic ABC-transporters in rats
-
van Waarde WM, Verkade HJ, Wolters H, Havinga R, Baller J, Bloks V, et al. Differential effects of streptozotocin-induced diabetes on expression of hepatic ABC-transporters in rats. Gastroenterology. 2002;122:1842-1852.
-
(2002)
Gastroenterology
, vol.122
, pp. 1842-1852
-
-
Waarde, W.M.1
Verkade, H.J.2
Wolters, H.3
Havinga, R.4
Baller, J.5
Bloks, V.6
-
19
-
-
0016693262
-
Blood-brain barrier lesions in acute hypertension in rabbits after unilateral X-ray exposure of brain
-
Blomstrand C, Johansson B, Rosengren B. Blood-brain barrier lesions in acute hypertension in rabbits after unilateral X-ray exposure of brain. Acta Neuropathol. 1975;31:97-102.
-
(1975)
Acta Neuropathol
, vol.31
, pp. 97-102
-
-
Blomstrand, C.1
Johansson, B.2
Rosengren, B.3
-
20
-
-
0019404014
-
Evaluation of the dye-protein tracers in pathophysiology of the blood-brain barrier
-
Wolman M, Klatzo I, Chui E, Wilmes F, Nishimoto K, Fujiwara K, et al. Evaluation of the dye-protein tracers in pathophysiology of the blood-brain barrier. Acta Neuropathol. 1981;54:55-61.
-
(1981)
Acta Neuropathol
, vol.54
, pp. 55-61
-
-
Wolman, M.1
Klatzo, I.2
Chui, E.3
Wilmes, F.4
Nishimoto, K.5
Fujiwara, K.6
-
21
-
-
0242385616
-
Altered blood-brain barrier permeability and its effect on the distribution of evans blue and sodium fluorescein in the rat brain applied by intracarotid injection
-
Kozler P, Pokorny J. Altered blood-brain barrier permeability and its effect on the distribution of evans blue and sodium fluorescein in the rat brain applied by intracarotid injection. Physiol Res. 2003;52:607-614.
-
(2003)
Physiol Res
, vol.52
, pp. 607-614
-
-
Kozler, P.1
Pokorny, J.2
-
22
-
-
0023062616
-
Animal models utilized in the research of diabetes mellitus-with special reference in insulitis-associated diabetes
-
Tarui S, Yamada K, Hanafusa T. Animal models utilized in the research of diabetes mellitus-with special reference in insulitis-associated diabetes. Prog Clin Biol Res. 1987;229:211-223.
-
(1987)
Prog Clin Biol Res
, vol.229
, pp. 211-223
-
-
Tarui, S.1
Yamada, K.2
Hanafusa, T.3
-
23
-
-
0014034750
-
Light and electron microscopy of lesions in rats rendered diabetic with streptozotocin
-
Arison RN, Ciaccio EI, Glitzer MS, Cassaro JA, Pruss MP. Light and electron microscopy of lesions in rats rendered diabetic with streptozotocin. Diabetes. 1967;16:51-56.
-
(1967)
Diabetes
, vol.16
, pp. 51-56
-
-
Arison, R.N.1
Ciaccio, E.I.2
Glitzer, M.S.3
Cassaro, J.A.4
Pruss, M.P.5
-
24
-
-
0022538698
-
Differential effects of central nervous system depressants in long-sleep and short-sleep mice
-
Marley RJ, Miner LL, Wehner KM, Collins AC. Differential effects of central nervous system depressants in long-sleep and short-sleep mice. J Pharmacol Exp Ther. 1986;238:1028-1033.
-
(1986)
J Pharmacol Exp Ther
, vol.238
, pp. 1028-1033
-
-
Marley, R.J.1
Miner, L.L.2
Wehner, K.M.3
Collins, A.C.4
-
25
-
-
0036201150
-
Influence of the corticotrophin releasing hormone (CRH) on the brain-blood barrier permeability in cerebral ischemia in rats
-
Hendryk S, Jedrzefowska-szypulka H, Josko J, Jarzab B, Dohler KD. Influence of the corticotrophin releasing hormone (CRH) on the brain-blood barrier permeability in cerebral ischemia in rats. J Physiol Pharmacol. 2002;53:85-94.
-
(2002)
J Physiol Pharmacol
, vol.53
, pp. 85-94
-
-
Hendryk, S.1
Jedrzefowska-szypulka, H.2
Josko, J.3
Jarzab, B.4
Dohler, K.D.5
-
26
-
-
0041324708
-
Disruption of the type 1 inositol 1,4,5-trisphosphate receptor gene suppresses the morphine-induced antinociception in the mouse
-
Aoki T, Narita M, Ohnishi O, Mizuo K, Narita M, Yajima Y, et al. Disruption of the type 1 inositol 1,4,5-trisphosphate receptor gene suppresses the morphine-induced antinociception in the mouse. Neurosci Lett. 2003;350:69-72.
-
(2003)
Neurosci Lett
, vol.350
, pp. 69-72
-
-
Aoki, T.1
Narita, M.2
Ohnishi, O.3
Mizuo, K.4
Narita, M.5
Yajima, Y.6
-
27
-
-
0035108144
-
The effect of streptozotocin-induced diabetes on the release of excitotoxic and other amino acids from the ischemic rat cerebral cortex
-
discussion 390-391
-
Guyot LL, Diaz FG, O'Regan MH, Song D, Phillis JW. The effect of streptozotocin-induced diabetes on the release of excitotoxic and other amino acids from the ischemic rat cerebral cortex. Neurosurgery. 2001;48:385- 390;discussion 390-391.
-
(2001)
Neurosurgery
, vol.48
, pp. 385-390
-
-
Guyot, L.L.1
Diaz, F.G.2
O'Regan, M.H.3
Song, D.4
Phillis, J.W.5
-
28
-
-
0034992070
-
Modification of the effects of benzodiazepines on the exploratory behaviors of mice on a hole-board by diabetes
-
Kamei J, Ohsawa M, Tsuji M, Takeda H, Matsumiya T. Modification of the effects of benzodiazepines on the exploratory behaviors of mice on a hole-board by diabetes. Jpn J Pharmacol. 2001;86:47-54.
-
(2001)
Jpn J Pharmacol
, vol.86
, pp. 47-54
-
-
Kamei, J.1
Ohsawa, M.2
Tsuji, M.3
Takeda, H.4
Matsumiya, T.5
-
29
-
-
0032784403
-
Loratadine: A non-sedating antihistamine. Review of its effects on cognition, psychomotor performance, mood and sedation
-
Kay GG, Harris AG. Loratadine: a non-sedating antihistamine. Review of its effects on cognition, psychomotor performance, mood and sedation. Clin Exp Allergy. 1999;29 Suppl 3:147-150.
-
(1999)
Clin Exp Allergy
, vol.29
, Issue.SUPPL. 3
, pp. 147-150
-
-
Kay, G.G.1
Harris, A.G.2
-
30
-
-
0029567005
-
1-receptor occupancy in human subjects treated with epinastine, a second-generation antihistamine
-
1-receptor occupancy in human subjects treated with epinastine, a second-generation antihistamine. Methods Find Exp Clin Pharmacol. 1995;17:64-69.
-
(1995)
Methods Find Exp Clin Pharmacol
, vol.17
, pp. 64-69
-
-
Yanai, K.1
Ryu, J.H.2
Watanabe, T.3
Iwata, R.4
Ido, T.5
Asakura, M.6
-
31
-
-
0037228838
-
Increased blood-brain barrier permeability in type II diabetes demonstrated by gadolinium magnetic resonance imaging
-
Starr JM, Wardlaw J, Ferguson K, MacLullich A, Deary IJ, Marshall I. Increased blood-brain barrier permeability in type II diabetes demonstrated by gadolinium magnetic resonance imaging. J Neurol Neurosurg Psychiatry. 2003;74:70-76.
-
(2003)
J Neurol Neurosurg Psychiatry
, vol.74
, pp. 70-76
-
-
Starr, J.M.1
Wardlaw, J.2
Ferguson, K.3
MacLullich, A.4
Deary, I.J.5
Marshall, I.6
-
32
-
-
0021359214
-
Early changes in blood brain barrier permeability to small molecules after transient cerebral ischemia
-
Sage JI, Van Uitert RL, Duffy TE. Early changes in blood brain barrier permeability to small molecules after transient cerebral ischemia. Stroke. 1984;15:46-50.
-
(1984)
Stroke
, vol.15
, pp. 46-50
-
-
Sage, J.I.1
Van Uitert, R.L.2
Duffy, T.E.3
-
33
-
-
0020043377
-
The blood-brain barrier in renovascular hypertension
-
Mueller SM, Luft FC. The blood-brain barrier in renovascular hypertension. Stroke. 1982;13:229-234.
-
(1982)
Stroke
, vol.13
, pp. 229-234
-
-
Mueller, S.M.1
Luft, F.C.2
-
34
-
-
0037044901
-
Blood-brain barrier integrity is unaltered in human brain cortex with diabetes mellitus
-
Dai J, Vrensen GF, Schlingemann RO. Blood-brain barrier integrity is unaltered in human brain cortex with diabetes mellitus. Brain Res. 2002;954:311-316.
-
(2002)
Brain Res
, vol.954
, pp. 311-316
-
-
Dai, J.1
Vrensen, G.F.2
Schlingemann, R.O.3
-
35
-
-
0027339633
-
Terfenadine (Seldane®): A new drug for restoring sensitivity to multidrug resistant cancer cells
-
Hait WN, Gesmonde JF, Murren JR, Yang JM, Chen HX, Reiss M. Terfenadine (Seldane®): a new drug for restoring sensitivity to multidrug resistant cancer cells. Biochem Pharmacol. 1993;45:401-406.
-
(1993)
Biochem Pharmacol
, vol.45
, pp. 401-406
-
-
Hait, W.N.1
Gesmonde, J.F.2
Murren, J.R.3
Yang, J.M.4
Chen, H.X.5
Reiss, M.6
|