Genomic instability, mutations and expression analysis of the tumour suppressor genes p14ARF, p15INK4b, p16INK4a and p53 in actinic keratosis

Cancer Letters

Volumn 264, Issue 1, 2008, Pages 145-161

  Kanellou, P ^a   Zaravinos, A ^a   Zioga, M ^b   Stratigos, A ^b   Baritaki, S ^a,c   Soufla, G ^a   Zoras, O ^a   Spandidos, D A ^a  

^a UNIVERSITY OF CRETE   (Greece)

^b ANDREAS SYGROS HOSPITAL   (Greece)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Actinic keratosis; CDKN2A; CDKN2B; mRNA expression; MSI LOH; Mutations

Indexed keywords

ALANINE; ARGININE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; GLUTAMIC ACID; MESSENGER RNA; PROTEIN P53; THREONINE; VALINE;

ACTINIC KERATOSIS; ADULT; AGED; ALLELE; ARTICLE; CHROMOSOME 9P; CODON; DOWN REGULATION; EXON; FEMALE; GENE EXPRESSION PROFILING; GENE FREQUENCY; GENE LOCUS; GENE MUTATION; GENETIC POLYMORPHISM; GENOMIC INSTABILITY; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MALE; MICROSATELLITE INSTABILITY; MISSENSE MUTATION; MUTATIONAL ANALYSIS; P14ARF GENE; P15INK4B GENE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; SUN EXPOSURE; TUMOR SUPPRESSOR GENE;

AGED; AGED, 80 AND OVER; BASE SEQUENCE; CARCINOMA, SQUAMOUS CELL; CYCLIN-DEPENDENT KINASE INHIBITOR P15; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA MUTATIONAL ANALYSIS; FEMALE; GENOMIC INSTABILITY; HUMANS; KERATOSIS; LOSS OF HETEROZYGOSITY; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PRECANCEROUS CONDITIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P14ARF; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 42649116089     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2008.01.042     Document Type: Article

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