p16(MTS1/CDK41) mutations and concomitant loss of heterozygosity at 9p21-23 are frequent events in squamous cell carcinoma of the larynx

Oncogene

Volumn 15, Issue 12, 1997, Pages 1445-1453

  Jares, Pedro ^a,b   Fernández, Pedro L ^a   Nadal, Alfons ^c   Cazorla, Maite ^a   Hernández, Lluís ^a   Pinyol, Magda ^a   Hernández, Silvia ^a   Traserra, Jose ^a   Cardesa, Antonio ^a   Campo, Elías ^a,b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITY OF LLEIDA   (Spain)

^c Hospital Casa de Maternitat   (Spain)

Author keywords

Larynx; LOH 9p21 23; p16(MTS1 CDK41); Squamous cell carcinoma

Indexed keywords

CYCLIN D1; PROTEIN P16; MICROSATELLITE DNA; PROTEIN P16INK4A;

ARTICLE; CHROMOSOME 9P; CLINICAL ARTICLE; DNA METHYLATION; GENE AMPLIFICATION; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LARYNX CARCINOMA; LYMPH NODE METASTASIS; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; AGED; AMINO ACID SUBSTITUTION; BIOSYNTHESIS; CANCER INVASION; CANCER STAGING; CHROMOSOME 9; CHROMOSOME MAP; FEMALE; FRAMESHIFT MUTATION; GENE DELETION; GENETICS; LARYNX TUMOR; MALE; MIDDLE AGED; MUTATION; PATHOLOGY; POINT MUTATION; POLYMERASE CHAIN REACTION; RNA SPLICING;

AGED; AMINO ACID SUBSTITUTION; CARCINOMA, SQUAMOUS CELL; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 9; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P16; FEMALE; FRAMESHIFT MUTATION; HUMANS; LARYNGEAL NEOPLASMS; LOSS OF HETEROZYGOSITY; LYMPHATIC METASTASIS; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; MUTATION; NEOPLASM INVASIVENESS; NEOPLASM STAGING; POINT MUTATION; POLYMERASE CHAIN REACTION; RNA SPLICING; SEQUENCE DELETION;

EID: 0030611596     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1201309     Document Type: Article

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