Effects of furanocoumarin derivatives in grapefruit juice on nifedipine pharmacokinetics in rats

Pharmaceutical Research

Volumn 18, Issue 2, 2001, Pages 177-182

  Mohri, K ^a   Uesawa, Y ^a  

^a MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Bergamottin; First pass effect; Furanocoumarin; Grapefruit juice; Nifedipine; Pharmacokinetic interaction

Indexed keywords

6',7' DIHYDROXYBERGAMOTTIN; BERGAMOTTIN; BERGAPTOL; CYTOCHROME P450; FUROCOUMARIN DERIVATIVE; NIFEDIPINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; ENZYME INHIBITION; FIRST PASS EFFECT; FOOD DRUG INTERACTION; FRUIT JUICE; GRAPEFRUIT JUICE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTESTINE ABSORPTION; MALE; MICROSOME; NONHUMAN; ORANGE JUICE; PRIORITY JOURNAL; RAT;

ANIMALS; AREA UNDER CURVE; CALCIUM CHANNEL BLOCKERS; CITRUS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; FOOD-DRUG INTERACTIONS; MALE; NIFEDIPINE; PSORALENS; RATS; RATS, WISTAR;

EID: 0034948448     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011028401189     Document Type: Article

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