-
1
-
-
0028948839
-
A theoretical basis for a biopharmaceutical drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability
-
AMIDON, G.L.; LENNERNÄS, H.; SHAH, V.P.; CRISON, J.R. A theoretical basis for a biopharmaceutical drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm. Res., v.12, n.3, p.413-420, 1995.
-
(1995)
Pharm. Res
, vol.12
, Issue.3
, pp. 413-420
-
-
AMIDON, G.L.1
LENNERNÄS, H.2
SHAH, V.P.3
CRISON, J.R.4
-
2
-
-
0031413702
-
Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond
-
ARTURSSON, P.; BORCHARD, R.T. Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond. Pharm. Res., v.14, n.12, p.1655-1658, 1997.
-
(1997)
Pharm. Res
, vol.14
, Issue.12
, pp. 1655-1658
-
-
ARTURSSON, P.1
BORCHARD, R.T.2
-
3
-
-
0025329248
-
Epithelial transport of drug in cell culture. II: Effect of extracellular calcium concentration on paracellular transport of drugs of different lipophilicities across monolayers of intestinal epithelial (Caco-2) cells
-
ARTURSSON, P.; MAGNUSSON, C. Epithelial transport of drug in cell culture. II: Effect of extracellular calcium concentration on paracellular transport of drugs of different lipophilicities across monolayers of intestinal epithelial (Caco-2) cells. J. Pharm. Sci., v.79, n.7, p.595-600, 1990.
-
(1990)
J. Pharm. Sci
, vol.79
, Issue.7
, pp. 595-600
-
-
ARTURSSON, P.1
MAGNUSSON, C.2
-
4
-
-
0029056705
-
Absorption characteristics of chemical modified-insulin derivatives with various fatty acids in the small and large intestine
-
ASADA, H.; DOUEN, T.; WAKI, M.; ADACHI, S.; FUJITA, T.; YAMAMOTO, A.; MURANISHI, S. Absorption characteristics of chemical modified-insulin derivatives with various fatty acids in the small and large intestine. J. Pharm. Sci., v.84, p.682-687, 1995.
-
(1995)
J. Pharm. Sci
, vol.84
, pp. 682-687
-
-
ASADA, H.1
DOUEN, T.2
WAKI, M.3
ADACHI, S.4
FUJITA, T.5
YAMAMOTO, A.6
MURANISHI, S.7
-
5
-
-
0025061063
-
Effects of phlorizin and sodium on glucose-elicited alterations of cell junctions in intestinal epithelia
-
ATISOOK, K.; CARLSON, S.; MADARA, J.L. Effects of phlorizin and sodium on glucose-elicited alterations of cell junctions in intestinal epithelia. Am. J. Physiol., v.258, p. c77-c85, 1990.
-
(1990)
Am. J. Physiol
, vol.258
-
-
ATISOOK, K.1
CARLSON, S.2
MADARA, J.L.3
-
6
-
-
42149195830
-
-
AUNGST, B.; SHEN, D.D. Gastrointestinal absorption of toxic agents. In: ROZMAN, K.; HANNINEN, O. (Eds.), gastrointestinal toxicology. Elsevier, Amsterdam, 1986. p 29-56.
-
AUNGST, B.; SHEN, D.D. Gastrointestinal absorption of toxic agents. In: ROZMAN, K.; HANNINEN, O. (Eds.), gastrointestinal toxicology. Elsevier, Amsterdam, 1986. p 29-56.
-
-
-
-
8
-
-
0034888569
-
In vitro-in vivo correlation (IVIVC) models for metformin after administration of modified-release (MR) oral dosage forms to healthy human volunteers
-
BALAN, G.; TIMMINS, P.; GREENE, D.S.; MARATHE, P.H. In vitro-in vivo correlation (IVIVC) models for metformin after administration of modified-release (MR) oral dosage forms to healthy human volunteers. J. Pharm. Sci., v.90, p.1176-1185, 2001.
-
(2001)
J. Pharm. Sci
, vol.90
, pp. 1176-1185
-
-
BALAN, G.1
TIMMINS, P.2
GREENE, D.S.3
MARATHE, P.H.4
-
9
-
-
0034458680
-
Current methodologies used for evaluation of intestinal permeability and absorption
-
BALIMANE, P.V.; CHONG, S.; MORRISON, R.A. Current methodologies used for evaluation of intestinal permeability and absorption. J. Pharmacol. Toxicol. Methods, v.44, p. 301-312, 2000.
-
(2000)
J. Pharmacol. Toxicol. Methods
, vol.44
, pp. 301-312
-
-
BALIMANE, P.V.1
CHONG, S.2
MORRISON, R.A.3
-
11
-
-
0031659639
-
An improved everted gut sac as a simple and accurate technique measure paracellular transport across the small intestine
-
BARTHE, L.; WOODLEY, J.F.; KENWORTHY, S.; HOUIN, G. An improved everted gut sac as a simple and accurate technique measure paracellular transport across the small intestine. Eur. J. Drug Metab. Pharmacokinet., v.23, n.2, p.313-323, 1998.
-
(1998)
Eur. J. Drug Metab. Pharmacokinet
, vol.23
, Issue.2
, pp. 313-323
-
-
BARTHE, L.1
WOODLEY, J.F.2
KENWORTHY, S.3
HOUIN, G.4
-
12
-
-
2442719906
-
Unmasking the dynamic interplay between efflux transporters and metabolic enzymes
-
BENET, L.Z.; CUMMINS, C.L.; WU, C.Y. Unmasking the dynamic interplay between efflux transporters and metabolic enzymes. Int. J. Pharm., v.277, p.3-9, 2004.
-
(2004)
Int. J. Pharm
, vol.277
, pp. 3-9
-
-
BENET, L.Z.1
CUMMINS, C.L.2
WU, C.Y.3
-
13
-
-
0037081788
-
Influence of t-buthylhydroquinone and b-naphythoflavone on formation and transport of 4-methylumbelliferone glucuronide in Caco-2/TC-7 cell monolayers
-
BOCK-HENNIG B.S.; KÖHLE C.; NILL K.; BOCK, K.W. Influence of t-buthylhydroquinone and b-naphythoflavone on formation and transport of 4-methylumbelliferone glucuronide in Caco-2/TC-7 cell monolayers. Biochem. Pharmacol., v.63, p.123-128, 2002.
-
(2002)
Biochem. Pharmacol
, vol.63
, pp. 123-128
-
-
BOCK-HENNIG, B.S.1
KÖHLE, C.2
NILL, K.3
BOCK, K.W.4
-
14
-
-
42149095750
-
-
BRASIL. RE no 482, de 19 de março de 2002. Guia para estudos de correlação in vitro in vivo (CIVIV). Via Internet, no endereço eletrônico. Disponível em http://e-legis.bvs.br/ leisref/public/showAct.php?id=1237&word=. Acesso em 10 jun 2005.
-
BRASIL. RE no 482, de 19 de março de 2002. "Guia para estudos de correlação in vitro in vivo (CIVIV)". Via Internet, no endereço eletrônico. Disponível em http://e-legis.bvs.br/ leisref/public/showAct.php?id=1237&word=. Acesso em 10 jun 2005.
-
-
-
-
15
-
-
0030069942
-
The past, present, and future of tableting technology
-
ÇELIK, M. The past, present, and future of tableting technology. Drug Develop. Ind. Pharm., v.22, n.1, p.1-10, 1996.
-
(1996)
Drug Develop. Ind. Pharm
, vol.22
, Issue.1
, pp. 1-10
-
-
ÇELIK, M.1
-
16
-
-
0030614844
-
Physicochemical and physiological mechanisms for the effects of food on drug absorption: The role of lipids and pH
-
CHARMAN, W.N.; PORTER, C.J.H.; MITHANI, S.; DRESSMAN, J.B. Physicochemical and physiological mechanisms for the effects of food on drug absorption: The role of lipids and pH. J. Pharm. Sci., v.86, n.3, p.269-279, 1997.
-
(1997)
J. Pharm. Sci
, vol.86
, Issue.3
, pp. 269-279
-
-
CHARMAN, W.N.1
PORTER, C.J.H.2
MITHANI, S.3
DRESSMAN, J.B.4
-
17
-
-
0035416240
-
Prediction of pharmacokinetics properties using experimental approaches during early drug discovery
-
CHATURVEDI, P.R.; DECKER, C.J.; ODINECS, A. Prediction of pharmacokinetics properties using experimental approaches during early drug discovery. Curr. Opin. Chem. Biol., v. 5, p. 452-463, 2001.
-
(2001)
Curr. Opin. Chem. Biol
, vol.5
, pp. 452-463
-
-
CHATURVEDI, P.R.1
DECKER, C.J.2
ODINECS, A.3
-
18
-
-
0043028198
-
The absorption behavior of cyclosporin A lecithin vesicles in rat intestinal tissue
-
CHEN, Y; PING Q.; GUO, J.; WENLI, L.; GAO, J. The absorption behavior of cyclosporin A lecithin vesicles in rat intestinal tissue. Int. J. Pharm., v. 261, p.21-26, 2003.
-
(2003)
Int. J. Pharm
, vol.261
, pp. 21-26
-
-
CHEN, Y.1
PING, Q.2
GUO, J.3
WENLI, L.4
GAO, J.5
-
19
-
-
0029939330
-
In vitro permeability through Caco-2 cells is not quantitatively predictive of in vivo absorption for pe0ptide like drugs absorbed via the dipeptide transporter system
-
CHONG, S.; DANDO, S.; SOUCEK, K.; MORRISON, R. In vitro permeability through Caco-2 cells is not quantitatively predictive of in vivo absorption for pe0ptide like drugs absorbed via the dipeptide transporter system. Pharm. Res., v.13, p.120-123, 1996.
-
(1996)
Pharm. Res
, vol.13
, pp. 120-123
-
-
CHONG, S.1
DANDO, S.2
SOUCEK, K.3
MORRISON, R.4
-
20
-
-
0031422699
-
Evaluation of Biocat intestinal epithelium differentiation environment (3-day cultured Caco-2 cells) as na absorption screening model with improved productivity
-
CHONG, S.; DANDO, S.; MORRISON, R. Evaluation of Biocat intestinal epithelium differentiation environment (3-day cultured Caco-2 cells) as na absorption screening model with improved productivity. Pharm. Res., v.14, p.1835-1837, 1997.
-
(1997)
Pharm. Res
, vol.14
, pp. 1835-1837
-
-
CHONG, S.1
DANDO, S.2
MORRISON, R.3
-
21
-
-
0033780930
-
Bioequivalência de medicamentos: Objetivos, parâmetros farmacocinéticos, delineamento experimental e critérios de avaliação.
-
São Paulo, v
-
CONCIGLIERI, V.O.; STORPIRITIS, S. Bioequivalência de medicamentos: objetivos, parâmetros farmacocinéticos, delineamento experimental e critérios de avaliação. Rev. Bras. Cienc. Farm., São Paulo, v.36, p.13-21, 2000.
-
(2000)
Rev. Bras. Cienc. Farm
, vol.36
, pp. 13-21
-
-
CONCIGLIERI, V.O.1
STORPIRITIS, S.2
-
22
-
-
0037416093
-
Intestinal permeability of chlropyrifos using the single-pass intestinal perfusion method in the rat
-
COOK, T.J.; SHENOY, S.S. Intestinal permeability of chlropyrifos using the single-pass intestinal perfusion method in the rat. Toxicol., v.184, p.125-133, 2003.
-
(2003)
Toxicol
, vol.184
, pp. 125-133
-
-
COOK, T.J.1
SHENOY, S.S.2
-
23
-
-
0002224078
-
Guidelines for dissolution testing
-
New York, v
-
COX, D.C.; DOUGLAS, C.C.; FURMAN, W.B.; KIRCHHOEFER, R.D.; MYRICK, J.W. Guidelines for dissolution testing. Pharm. Technol., New York, v.2, p.41-53, 1978.
-
(1978)
Pharm. Technol
, vol.2
, pp. 41-53
-
-
COX, D.C.1
DOUGLAS, C.C.2
FURMAN, W.B.3
KIRCHHOEFER, R.D.4
MYRICK, J.W.5
-
24
-
-
0031453871
-
Level B and C in vivo/in vitro correlations: Statistical considerations
-
CUTLER, D.J.; BEYSSAC, E.; AIACHE, J.M. Level B and C in vivo/in vitro correlations: statistical considerations. Int. J. Pharm., v.158, p.185-193, 1997.
-
(1997)
Int. J. Pharm
, vol.158
, pp. 185-193
-
-
CUTLER, D.J.1
BEYSSAC, E.2
AIACHE, J.M.3
-
25
-
-
0035078138
-
Anatomical and physiological parameters affecting gastrointestinal absorption in humans and rats
-
DESESSO, J.M.; JACOBSON, C.F. Anatomical and physiological parameters affecting gastrointestinal absorption in humans and rats. Food Chem. Toxicol., v.39, p.209-228, 2001.
-
(2001)
Food Chem. Toxicol
, vol.39
, pp. 209-228
-
-
DESESSO, J.M.1
JACOBSON, C.F.2
-
26
-
-
33747373878
-
A century of dissolution research: From Noyes and Whitney to the biopharmaceutics classification system
-
DOKOUMETZIDIS, A.; MACHERAS, P. A century of dissolution research: from Noyes and Whitney to the biopharmaceutics classification system. Int. J. Pharm., v. 321, p. 1-11, 2006.
-
(2006)
Int. J. Pharm
, vol.321
, pp. 1-11
-
-
DOKOUMETZIDIS, A.1
MACHERAS, P.2
-
27
-
-
0022070123
-
Absorption potential: Estimating the fraction absorbed for orally administered compounds
-
DRESSMAN, J.B.; AMIDON, G.L.; FLEISHER, D. Absorption potential: estimating the fraction absorbed for orally administered compounds. J. Pharm. Sci., v. 74, p. 598-599, 1985.
-
(1985)
J. Pharm. Sci
, vol.74
, pp. 598-599
-
-
DRESSMAN, J.B.1
AMIDON, G.L.2
FLEISHER, D.3
-
28
-
-
0031913402
-
Dissolution testing as a prognostic tool for oral drug absorption: Immediate release dosage forms
-
DRESSMAN, J.B.; AMIDON, G.L.; REPPAS, C.; SHAH, V.P. Dissolution testing as a prognostic tool for oral drug absorption: immediate release dosage forms. Pharm. Res., v. 15, n.1, 1998.
-
(1998)
Pharm. Res
, vol.15
, Issue.1
-
-
DRESSMAN, J.B.1
AMIDON, G.L.2
REPPAS, C.3
SHAH, V.P.4
-
29
-
-
0039697009
-
The relationship between in vitro drug dissolution and in vivo absorption
-
DUNE, A.; DEVANE, J.; O'HARA, T. The relationship between in vitro drug dissolution and in vivo absorption. Statistician, v.48, p.125-133, 1999.
-
(1999)
Statistician
, vol.48
, pp. 125-133
-
-
DUNE, A.1
DEVANE, J.2
O'HARA, T.3
-
30
-
-
0031900490
-
Development and internal validation of an in vitro-in vivo correlation for a hydrophilic metoprolol tartrate extended release tablet formulation
-
EDDINGTON, N.D.; MARROUM, P.; UPPOOR, R.; HUSSAIN, A.; AUGSBURGER, L. Development and internal validation of an in vitro-in vivo correlation for a hydrophilic metoprolol tartrate extended release tablet formulation. Pharm. Res., v.15, p.466-473, 1998.
-
(1998)
Pharm. Res
, vol.15
, pp. 466-473
-
-
EDDINGTON, N.D.1
MARROUM, P.2
UPPOOR, R.3
HUSSAIN, A.4
AUGSBURGER, L.5
-
31
-
-
42149180970
-
-
FARMACOPÉIA brasileira. 4.ed. São Paulo: Atheneu, 1988. pt.1.
-
FARMACOPÉIA brasileira. 4.ed. São Paulo: Atheneu, 1988. pt.1.
-
-
-
-
32
-
-
42149194803
-
Permeabilidade intestinal de intestino delgado de ratos, preservados hipotermicamente com as soluções da Universidade de Wisconsin e Euro-Collins
-
GALVÄO, F. H. F.; WAITZBERG, D. L.; GONÇALVES, E. L.; SOARES, A. D. C. Permeabilidade intestinal de intestino delgado de ratos, preservados hipotermicamente com as soluções da Universidade de Wisconsin e Euro-Collins. Acta Cir. Bras., v. 8, p.54-8, 1993.
-
(1993)
Acta Cir. Bras
, vol.8
, pp. 54-58
-
-
GALVÄO, F.H.F.1
WAITZBERG, D.L.2
GONÇALVES, E.L.3
SOARES, A.D.C.4
-
33
-
-
0034671698
-
Charge-dependent interaction of self-emulsifying oil formulations with Caco-2 cells monolayers: Binding, effects on barrier function and cytotoxicity
-
GERSHANIK, T.; HALTNER, E.; LEHR, C.-M.; BENITA, S. Charge-dependent interaction of self-emulsifying oil formulations with Caco-2 cells monolayers: binding, effects on barrier function and cytotoxicity. Int. J. Pharm., v. 211, p. 29-36, 2000.
-
(2000)
Int. J. Pharm
, vol.211
, pp. 29-36
-
-
GERSHANIK, T.1
HALTNER, E.2
LEHR, C.-M.3
BENITA, S.4
-
34
-
-
0032948943
-
Prediction of dissolution-absorption relationships from a dissolution/ Caco-2 system
-
GINSKI, J.M.; POLLI, J.E. Prediction of dissolution-absorption relationships from a dissolution/ Caco-2 system. Int. J. Pharm., v. 177, p. 117-125, 1999.
-
(1999)
Int. J. Pharm
, vol.177
, pp. 117-125
-
-
GINSKI, J.M.1
POLLI, J.E.2
-
35
-
-
33947276437
-
Prediction of dissolution- absorption relationships from a continuous dissolution/Caco-2 system
-
GINSKI, J.M.; TANEJA, R.; POLLI, J.E. Prediction of dissolution- absorption relationships from a continuous dissolution/Caco-2 system. AAPS Pharm. Sci., v.1, n. 3, p. 1-12, 1999.
-
(1999)
AAPS Pharm. Sci
, vol.1
, Issue.3
, pp. 1-12
-
-
GINSKI, J.M.1
TANEJA, R.2
POLLI, J.E.3
-
36
-
-
0024408848
-
A correlation for permeabilities of passively transported compounds in monkey and rabbit jejunum
-
GRASS, G; SWEETANA, S. A correlation for permeabilities of passively transported compounds in monkey and rabbit jejunum. Pharm. Res., v.6, p. 857-862, 1989.
-
(1989)
Pharm. Res
, vol.6
, pp. 857-862
-
-
GRASS, G.1
SWEETANA, S.2
-
37
-
-
0031780682
-
Correlation between oral drug absorption in human, and apparent drug permeability in TC-7cells, a human epithelial intestinal cell line: Comparison with the parenteral Caco-2 cell line
-
GRES M.; JULIAN B.; BOURRIE M.; ROQUES, C.; BERGER, M.; BOULENC, X.; BERGER, Y.; FABRE, G.; Correlation between oral drug absorption in human, and apparent drug permeability in TC-7cells, a human epithelial intestinal cell line: comparison with the parenteral Caco-2 cell line. Pharm. Res., v. 15, p. 726-733, 1998.
-
(1998)
Pharm. Res
, vol.15
, pp. 726-733
-
-
GRES, M.1
JULIAN, B.2
BOURRIE, M.3
ROQUES, C.4
BERGER, M.5
BOULENC, X.6
BERGER, Y.7
FABRE, G.8
-
38
-
-
0030737622
-
Studies on dissolution testing of the nifedipine gastrointestinal therapeutic system. I. description of a two phase in vitro dissolution test
-
GRUNDY, J.S.; ANDERSON, K.E.; ROGERS, J.A.; FOSTER, R.T. Studies on dissolution testing of the nifedipine gastrointestinal therapeutic system. I. description of a two phase in vitro dissolution test. J. Control. Release, v. 48, p. 1-8, 1997.
-
(1997)
J. Control. Release
, vol.48
, pp. 1-8
-
-
GRUNDY, J.S.1
ANDERSON, K.E.2
ROGERS, J.A.3
FOSTER, R.T.4
-
39
-
-
42149169522
-
-
GUIDANCE for industry: waiver of in vivo bioavailability and bioequivalence studies for immediate-release solid oral dosage forms based on biopharmaceutics classification system. Rockville: FDA. 2000. 13p.
-
GUIDANCE for industry: waiver of in vivo bioavailability and bioequivalence studies for immediate-release solid oral dosage forms based on biopharmaceutics classification system. Rockville: FDA. 2000. 13p.
-
-
-
-
40
-
-
0041882163
-
-
HE, X.; SUGAWARA, M.; KOBAYASHI, M.; TAKEKUMA, Y.; MIYAZAKI, K. Na in vitro system for prediction of oral absorption of relatively water-soluble drugs and ester prodrugs. Int. J. Pharm., v. 263, p. 35-44, 2003.
-
HE, X.; SUGAWARA, M.; KOBAYASHI, M.; TAKEKUMA, Y.; MIYAZAKI, K. Na in vitro system for prediction of oral absorption of relatively water-soluble drugs and ester prodrugs. Int. J. Pharm., v. 263, p. 35-44, 2003.
-
-
-
-
41
-
-
0003655637
-
The absorption window: Fact or fiction?
-
HITZ, J. The absorption window: fact or fiction? Pharm. Int., p. 175-178, 1984.
-
(1984)
Pharm. Int
, pp. 175-178
-
-
HITZ, J.1
-
42
-
-
0025203031
-
Gastrointestinal transit of nondisintegration, nonerodible oral dosage forms in pigs
-
HOSSAIN, M.; ABRAMOWITZ, W.; WATROUS, B.J.; SZPUNAR, G.J.; AYREES, J.W. Gastrointestinal transit of nondisintegration, nonerodible oral dosage forms in pigs. Pharm. Res., v. 7, p. 1163-1166, 1990.
-
(1990)
Pharm. Res
, vol.7
, pp. 1163-1166
-
-
HOSSAIN, M.1
ABRAMOWITZ, W.2
WATROUS, B.J.3
SZPUNAR, G.J.4
AYREES, J.W.5
-
43
-
-
0037331236
-
Isolation and characterization of Caco-2 subclones expressing high levels of multidrug resistance protein efflux transporter
-
HORIE, K.; TANG, F.; BORCHARDT, R.T. Isolation and characterization of Caco-2 subclones expressing high levels of multidrug resistance protein efflux transporter. Pharm. Res., v.20, p. 161-167, 2003.
-
(2003)
Pharm. Res
, vol.20
, pp. 161-167
-
-
HORIE, K.1
TANG, F.2
BORCHARDT, R.T.3
-
44
-
-
0032949615
-
MDCK (Madin-Darby canine kidney) cells: A tool for membrane permeability screening
-
IRVINE, J.D.; TAKAHASHI, L.; LOCKHART, K.; CHEONG, J.; TOLAN, J.W.; SELICK, H.E.; GROVE, J.R. MDCK (Madin-Darby canine kidney) cells: a tool for membrane permeability screening. J. Pharm. Sci., v. 88, p. 28-33, 1999.
-
(1999)
J. Pharm. Sci
, vol.88
, pp. 28-33
-
-
IRVINE, J.D.1
TAKAHASHI, L.2
LOCKHART, K.3
CHEONG, J.4
TOLAN, J.W.5
SELICK, H.E.6
GROVE, J.R.7
-
45
-
-
0141566892
-
Function expression of the human thiazide-sensitive NaCl cotransporter in Madin-Darby Canine Kidney Cells
-
JONG, J.C.; WILLEMS, P.H.G.M.; HEUVEL, L.P.W.J.V.D.; KNOERS, N.V.A.M.; BINDELS, R.J.M. Function expression of the human thiazide-sensitive NaCl cotransporter in Madin-Darby Canine Kidney Cells. J. Am. Soc. Nephrol., v. 14, p. 2428-2435, 2003.
-
(2003)
J. Am. Soc. Nephrol
, vol.14
, pp. 2428-2435
-
-
JONG, J.C.1
WILLEMS, P.H.G.M.2
V.D. HEUVEL, L.P.W.J.3
KNOERS, N.V.A.M.4
BINDELS, R.J.M.5
-
46
-
-
0025968837
-
Dietary regulation of intestinal ascorbate uptake in guinea pigs
-
KARASOV, W.H.; DARKEN, B.W.; BOTTUM, M.C. Dietary regulation of intestinal ascorbate uptake in guinea pigs. Am. J. Physiol., v. 260, p. G108-G118, 1991.
-
(1991)
Am. J. Physiol
, vol.260
-
-
KARASOV, W.H.1
DARKEN, B.W.2
BOTTUM, M.C.3
-
47
-
-
3242728351
-
Molecular properties of WHO essential drugs and provisional biopharmaceutical classification
-
KASSIN, N.A.; WHITEHOUSE, M.; RAMACHANDRAN, C.; BERMEJO, M.; LENNERNAS, H.; HUSSAIN, A.S.; JUNGINGER, H.E; STAVICHANSKY, S.A.; MIDHA, K.K.; SHAH, V.P.; AMIDON, G.L. Molecular properties of WHO essential drugs and provisional biopharmaceutical classification. Mol. Pharm., v. 1, p. 85-96, 2003.
-
(2003)
Mol. Pharm
, vol.1
, pp. 85-96
-
-
KASSIN, N.A.1
WHITEHOUSE, M.2
RAMACHANDRAN, C.3
BERMEJO, M.4
LENNERNAS, H.5
HUSSAIN, A.S.6
JUNGINGER, H.E.7
STAVICHANSKY, S.A.8
MIDHA, K.K.9
SHAH, V.P.10
AMIDON, G.L.11
-
48
-
-
85009583484
-
Intestinal absorption of drug mediated by drug transporters: Mechanisms and regulation
-
KATSURA, T.; INUI, K. Intestinal absorption of drug mediated by drug transporters: mechanisms and regulation. Drug Metab. Pharmacokin., v.18, n.1, p. 1-15, 2003.
-
(2003)
Drug Metab. Pharmacokin
, vol.18
, Issue.1
, pp. 1-15
-
-
KATSURA, T.1
INUI, K.2
-
49
-
-
0028906632
-
Estimation of agitation intensity in the GI tact in humans and dogs based on in vitro/in vivo correlation
-
KATORI, N.; AOYAGI, N.; TERAO, T. Estimation of agitation intensity in the GI tact in humans and dogs based on in vitro/in vivo correlation. Pharm. Res., v. 12, n. 2, p. 237-243, 1995.
-
(1995)
Pharm. Res
, vol.12
, Issue.2
, pp. 237-243
-
-
KATORI, N.1
AOYAGI, N.2
TERAO, T.3
-
50
-
-
0030606871
-
-
KHAN, M.Z.I. dissolution testing for sustained or controlled release oral dosage forms and correlation with in vivo data: challenges and opportunities. Int. J. Pharm., v. 140, p. 131-143, 1996.
-
KHAN, M.Z.I. dissolution testing for sustained or controlled release oral dosage forms and correlation with in vivo data: challenges and opportunities. Int. J. Pharm., v. 140, p. 131-143, 1996.
-
-
-
-
51
-
-
0035912914
-
Development of a new system for prediction of drug absorption that takes into account drug dissolution and pH change in the gastro-intestinal tract
-
KOBAYASHI, M.; SADA, N.; SUGAWARA, M.; ISEKI, K.; MIYAZAKI, K. Development of a new system for prediction of drug absorption that takes into account drug dissolution and pH change in the gastro-intestinal tract. Int. J. Pharm., v. 221, p. 87-94, 2001.
-
(2001)
Int. J. Pharm
, vol.221
, pp. 87-94
-
-
KOBAYASHI, M.1
SADA, N.2
SUGAWARA, M.3
ISEKI, K.4
MIYAZAKI, K.5
-
52
-
-
0027931130
-
Intestinal cell culture models
-
LABOISSE, C.L.; JARRY, A.; BOU-HANNA, C.; MELIN, D.; VALLETTE, G. Intestinal cell culture models. Eur. J. Pharm. Sci., v. 2, p. 32-38, 1994.
-
(1994)
Eur. J. Pharm. Sci
, vol.2
, pp. 32-38
-
-
LABOISSE, C.L.1
JARRY, A.2
BOU-HANNA, C.3
MELIN, D.4
VALLETTE, G.5
-
53
-
-
0034712893
-
Development of a more rapid, reduced serum culture system for Caco-2 monolayers and a application to the biopharmaceutics classification system
-
LENTZ, K.A.; HAYASHI, J.; LUCISANO, L.J.; POLLI, J.E. Development of a more rapid, reduced serum culture system for Caco-2 monolayers and a application to the biopharmaceutics classification system. Int. J. Pharm., v. 200, p. 41-51, 2000.
-
(2000)
Int. J. Pharm
, vol.200
, pp. 41-51
-
-
LENTZ, K.A.1
HAYASHI, J.2
LUCISANO, L.J.3
POLLI, J.E.4
-
54
-
-
0035987891
-
-
LUO, F.R.; PARANJPE, P.V.; GUO, A.; RUBIN, E.; SINKO, P. transport of irinotecan in Caco-2 cells and MDCK II cells over expressing efflux transporters Pgp, cMOAT, and MRP1. Drug Metab. Dispos., v. 30, p. 763-70, 2002.
-
LUO, F.R.; PARANJPE, P.V.; GUO, A.; RUBIN, E.; SINKO, P. transport of irinotecan in Caco-2 cells and MDCK II cells over expressing efflux transporters Pgp, cMOAT, and MRP1. Drug Metab. Dispos., v. 30, p. 763-70, 2002.
-
-
-
-
55
-
-
0030796952
-
Gastrointestinal drug absorption: Is it time to consider heterogeneity as well as homogeneity?
-
MACHERAS, P.; ARGYRAKIS, P. Gastrointestinal drug absorption: is it time to consider heterogeneity as well as homogeneity? Pharm. Res., v. 14, p. 842-847, 1997.
-
(1997)
Pharm. Res
, vol.14
, pp. 842-847
-
-
MACHERAS, P.1
ARGYRAKIS, P.2
-
56
-
-
0031719032
-
-
MAKHEY, V.D.; GUO, A.; NORRIS D.A.; H.U. P.; YAN, J., SINKO, P.J. Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells. Pharm Res., v. 15, p.1160-7, 1998.
-
MAKHEY, V.D.; GUO, A.; NORRIS D.A.; H.U. P.; YAN, J., SINKO, P.J. Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells. Pharm Res., v. 15, p.1160-7, 1998.
-
-
-
-
57
-
-
0036825614
-
A dissolução in vitro na previsã;o da absorção oral de fármacos em formas farmacêuticas de liberação modificada.
-
MANADAS, R.; PINA, M.E.; VEIGA, F. A dissolução in vitro na previsã;o da absorção oral de fármacos em formas farmacêuticas de liberação modificada. Brazilian J. Pharm. Sci., v. 38, p. 375-400, 2002.
-
(2002)
Brazilian J. Pharm. Sci
, vol.38
, pp. 375-400
-
-
MANADAS, R.1
PINA, M.E.2
VEIGA, F.3
-
58
-
-
24944523222
-
Evidence of efflux-mediated and saturable absorption of rifampicin in rat intestine using the ligated loop and everted gut sac techniques
-
MARIAPPAN T.T.; SINGH S. Evidence of efflux-mediated and saturable absorption of rifampicin in rat intestine using the ligated loop and everted gut sac techniques. Mol Pharm., v.1, p.363-7, 2004.
-
(2004)
Mol Pharm
, vol.1
, pp. 363-367
-
-
MARIAPPAN, T.T.1
SINGH, S.2
-
59
-
-
27244453798
-
Desenvolvimento e validação de métodos de dissolução para formas farmacêuticas sólidas orais.
-
MARQUES, M.R.C. Desenvolvimento e validação de métodos de dissolução para formas farmacêuticas sólidas orais. Rev. Analytica, n.1, p. 48-51, 2002.
-
(2002)
Rev. Analytica
, Issue.1
, pp. 48-51
-
-
MARQUES, M.R.C.1
-
60
-
-
0141928631
-
Comparison of ceftibuten transport across Caco-2 cells and rat jejunum mounted on modified Using chambers
-
MENON, R.M.; BARR, W.H. Comparison of ceftibuten transport across Caco-2 cells and rat jejunum mounted on modified Using chambers. Biopharm. Drug Dispos., v. 24, p. 299-308, 2003.
-
(2003)
Biopharm. Drug Dispos
, vol.24
, pp. 299-308
-
-
MENON, R.M.1
BARR, W.H.2
-
61
-
-
19444382806
-
Ph-dependent passive and active transport of acidic drugs across Caco-2 cell monolayers
-
NEULROFF, S.; UNGELL, A.L.; ZAMORA, I.; ARTUSSON, P. Ph-dependent passive and active transport of acidic drugs across Caco-2 cell monolayers. Eur. J. Pharm. Sci., v. 25, p. 211-220, 2005.
-
(2005)
Eur. J. Pharm. Sci
, vol.25
, pp. 211-220
-
-
NEULROFF, S.1
UNGELL, A.L.2
ZAMORA, I.3
ARTUSSON, P.4
-
62
-
-
0023521841
-
Contribution of solvent drag through intercellular junctions to absorption of nutrients by the small intestine of the rat
-
PAPPENHEIMER, J.R.; REISS, K.Z. 1987. Contribution of solvent drag through intercellular junctions to absorption of nutrients by the small intestine of the rat. J. Memb. Biol., v. 100, p. 123-136, 1987.
-
(1987)
J. Memb. Biol
, vol.100
, pp. 123-136
-
-
PAPPENHEIMER, J.R.1
REISS, K.Z.2
-
63
-
-
0036172860
-
Compromised integrity of excised porcine intestinal epithelium obtained from the abattoir effects the outcome of in vitro particle uptake studies
-
PIETZONKA, P.; WALTER, E.; DUDA-JOHNER, S.; LANGGUTH, P.; MERKLE, H.P. Compromised integrity of excised porcine intestinal epithelium obtained from the abattoir effects the outcome of in vitro particle uptake studies. Eur. J. Pharm. Sci., v. 15, p. 39-47, 2002.
-
(2002)
Eur. J. Pharm. Sci
, vol.15
, pp. 39-47
-
-
PIETZONKA, P.1
WALTER, E.2
DUDA-JOHNER, S.3
LANGGUTH, P.4
MERKLE, H.P.5
-
64
-
-
0030017609
-
Novel approach to the analysis of in vitro-in vivo relationships
-
POLLI, J.E.; CRISON, J.R.; AMIDON, G.L. Novel approach to the analysis of in vitro-in vivo relationships. J. Pharm. Sci., v. 85, p. 753-761, 1996.
-
(1996)
J. Pharm. Sci
, vol.85
, pp. 753-761
-
-
POLLI, J.E.1
CRISON, J.R.2
AMIDON, G.L.3
-
65
-
-
0036145297
-
Comparison of bidirectional cephalexin transport across MDCK and Caco-2 cell monolayers: Interactions with peptide transporters
-
PUTNAM, W.S.; PAN, L.; TSUTSUI, K.; TAKAHASHI, L.; BENET, L.Z. Comparison of bidirectional cephalexin transport across MDCK and Caco-2 cell monolayers: Interactions with peptide transporters. Pharm. Res., v.19, p. 27-33, 2002
-
(2002)
Pharm. Res
, vol.19
, pp. 27-33
-
-
PUTNAM, W.S.1
PAN, L.2
TSUTSUI, K.3
TAKAHASHI, L.4
BENET, L.Z.5
-
66
-
-
0035818461
-
Correlation of "in vitro" release and "in vivo" absorption characteristics of rifampicin from ethylcellulose coated nonpareil beads
-
RAO, B.S.; SESHASAYANA, A., SARADHI, S.V.P.; KUMAR, N.R.; NARAYAN, C.P.S.; MURTHY, K.V.R. Correlation of "in vitro" release and "in vivo" absorption characteristics of rifampicin from ethylcellulose coated nonpareil beads. Int. J. Pharm., v. 230, p. 1-9, 2001.
-
(2001)
Int. J. Pharm
, vol.230
, pp. 1-9
-
-
RAO, B.S.1
SESHASAYANA, A.2
SARADHI, S.V.P.3
KUMAR, N.R.4
NARAYAN, C.P.S.5
MURTHY, K.V.R.6
-
67
-
-
0029953050
-
Drug absorption sites in the gastrintestinal tract and dosage forms for site-specific delivery
-
ROUGE, N.; BURI, P.; DOELKER, E. Drug absorption sites in the gastrintestinal tract and dosage forms for site-specific delivery. Int. J. Pharm., v. 136, p. 117-139, 1996.
-
(1996)
Int. J. Pharm
, vol.136
, pp. 117-139
-
-
ROUGE, N.1
BURI, P.2
DOELKER, E.3
-
68
-
-
0019412116
-
The uptake of distearoylphosphatidylcholine/cholesterol liposomes by rat intestinal sac in vitro
-
ROWLAND, R.N. ; WOODLEY, J.F. The uptake of distearoylphosphatidylcholine/cholesterol liposomes by rat intestinal sac in vitro. Biochim. Biophys. Acta, v. 673, p. 217-223, 1981.
-
(1981)
Biochim. Biophys. Acta
, vol.673
, pp. 217-223
-
-
ROWLAND, R.N.1
WOODLEY, J.F.2
-
69
-
-
0027497560
-
Comparison of the permeability characteristics of a human colonic epithelial (Caco-2) cell line to colon of rabbit, monkey, and dog intestine and human drug absorption
-
RUBAS, W.; JEZYK, N.; GRASS, G.M. Comparison of the permeability characteristics of a human colonic epithelial (Caco-2) cell line to colon of rabbit, monkey, and dog intestine and human drug absorption. Pharm. Res., v. 10, p. 113-118, 1993.
-
(1993)
Pharm. Res
, vol.10
, pp. 113-118
-
-
RUBAS, W.1
JEZYK, N.2
GRASS, G.M.3
-
70
-
-
0032865950
-
Correlation of two bioadhesion assays: The everted sac technique and the CAHN microbalance
-
SANTOS, C.A.; JACOB, J.S.; HETZOG, B.A.; FREEDMAN, B.D.; PRESS, D.L.; HARNPICHARNCHAI, P.; MATHIOWITZ, E. Correlation of two bioadhesion assays: The everted sac technique and the CAHN microbalance. J. Control. Rel., v. 61, p. 113-122, 1999.
-
(1999)
J. Control. Rel
, vol.61
, pp. 113-122
-
-
SANTOS, C.A.1
JACOB, J.S.2
HETZOG, B.A.3
FREEDMAN, B.D.4
PRESS, D.L.5
HARNPICHARNCHAI, P.6
MATHIOWITZ, E.7
-
71
-
-
0030472470
-
In-vitro dissolution profile comparison: Statistic and analysis, model dependent approach
-
SATHE, P.M.; TSONG, Y.; SHAH, V.P. In-vitro dissolution profile comparison: Statistic and analysis, model dependent approach. Pharm. Res., v. 13, p. 1799-1803, 1996.
-
(1996)
Pharm. Res
, vol.13
, pp. 1799-1803
-
-
SATHE, P.M.1
TSONG, Y.2
SHAH, V.P.3
-
72
-
-
0026098838
-
Species differences in percutaneous adsorption of nicorandil
-
SATO, K.; SUGIBAYASHI, K.; MORIMOTO, Y. Species differences in percutaneous adsorption of nicorandil. J. Pharm. Sci., v.80, p. 104-107, 1991.
-
(1991)
J. Pharm. Sci
, vol.80
, pp. 104-107
-
-
SATO, K.1
SUGIBAYASHI, K.2
MORIMOTO, Y.3
-
73
-
-
0025147050
-
In vitro and in vivo testing and correlation for oral controlled/modified-release dosage forms
-
SKELLY, J.P.; AMIDON, G.L.; BARR, W.H.; BENET, L.Z.; CARTER, J.E.; ROBINSON, J.R.; SHAH, V.P.; YACOBI, A. In vitro and in vivo testing and correlation for oral controlled/modified-release dosage forms. Pharm. Res., v. 7, p. 975-982, 1990.
-
(1990)
Pharm. Res
, vol.7
, pp. 975-982
-
-
SKELLY, J.P.1
AMIDON, G.L.2
BARR, W.H.3
BENET, L.Z.4
CARTER, J.E.5
ROBINSON, J.R.6
SHAH, V.P.7
YACOBI, A.8
-
74
-
-
0029553223
-
Biodisponibilidade e bioequivalência de medicamentos: Aspectos fundamentais para o planejamento e execução de estudos.
-
STORPIRTIS, S.; CONSIGLIERI, O.V. Biodisponibilidade e bioequivalência de medicamentos: Aspectos fundamentais para o planejamento e execução de estudos. Rev. Bras. Cienc. Farm., v. 31, p. 63-70, 1995.
-
(1995)
Rev. Bras. Cienc. Farm
, vol.31
, pp. 63-70
-
-
STORPIRTIS, S.1
CONSIGLIERI, O.V.2
-
75
-
-
0032773855
-
A conditionally immortalized epithelial cell line for studies of intestinal drug transport
-
TAVELIN S.; MILOVIC V.; OCKLIND G.; OLSSON S.; ARTURSSON P. A conditionally immortalized epithelial cell line for studies of intestinal drug transport. J. Pharmacol. Exper. Ther., v. 290, p. 1212-1221, 1998.
-
(1998)
J. Pharmacol. Exper. Ther
, vol.290
, pp. 1212-1221
-
-
TAVELIN, S.1
MILOVIC, V.2
OCKLIND, G.3
OLSSON, S.4
ARTURSSON, P.5
-
76
-
-
0037336533
-
Prediction of the oral absorption of low-permeability drugs using small intestine-like 2/4/A1 cell monolayers
-
TAVELIN S.; TAIPALENSUU, J.; SÖDERBERG, L.; MORRISON, R.; CHONG, S.; ARTURSSON P. Prediction of the oral absorption of low-permeability drugs using small intestine-like 2/4/A1 cell monolayers. Pharm. Res., v. 20, p. 397-405, 2003a.
-
(2003)
Pharm. Res
, vol.20
, pp. 397-405
-
-
TAVELIN, S.1
TAIPALENSUU, J.2
SÖDERBERG, L.3
MORRISON, R.4
CHONG, S.5
ARTURSSON, P.6
-
77
-
-
0037335192
-
Na improved cell culture model based on 2/4/A1 cell monolayers for studies of intestinal drug transport: Characterization of transport routes
-
TAVELIN, S.; TAIPALENSUU, J.; HALLBÖÖK, F.; VELLONEN, K-S.; MOORE, V.; ARTURSSON P. Na improved cell culture model based on 2/4/A1 cell monolayers for studies of intestinal drug transport: characterization of transport routes. Pharm. Res., v. 20, p. 373-381, 2003b.
-
(2003)
Pharm. Res
, vol.20
, pp. 373-381
-
-
TAVELIN, S.1
TAIPALENSUU, J.2
HALLBÖÖK, F.3
VELLONEN, K.-S.4
MOORE, V.5
ARTURSSON, P.6
-
78
-
-
42149112676
-
-
UNITED States Pharmacopeia: USP 29: The National Formulary: NF 24. Rockville: United States Pharmacopeial Convention, 2005. p.1064-1065, 1961-1963.
-
UNITED States Pharmacopeia: USP 29: The National Formulary: NF 24. Rockville: United States Pharmacopeial Convention, 2005. p.1064-1065, 1961-1963.
-
-
-
-
79
-
-
0035858365
-
Regulatory perspectives on in vitro (dissolution)/in vivo (bioavailability) correlations
-
UPPOOR, V.R.S. Regulatory perspectives on in vitro (dissolution)/in vivo (bioavailability) correlations. J. Control. Rel., v. 72, p. 127-132, 2001.
-
(2001)
J. Control. Rel
, vol.72
, pp. 127-132
-
-
UPPOOR, V.R.S.1
-
80
-
-
0242288651
-
Prostaglandin E2 stimulates sodium reabsorption in MDCK C7 cells, a renal collection duct principal cell model
-
WEGMANN, M.; NÜSING, R.M. Prostaglandin E2 stimulates sodium reabsorption in MDCK C7 cells, a renal collection duct principal cell model. Prostaglandins, Leukot. Essent. Fat. Acids, v. 69, p. 315-322, 2003.
-
(2003)
Prostaglandins, Leukot. Essent. Fat. Acids
, vol.69
, pp. 315-322
-
-
WEGMANN, M.1
NÜSING, R.M.2
-
81
-
-
33344454616
-
Glutathione and thiolated chitosan inhibit multidrug resistance P-glycoprotein activity in excised small intestine
-
WERLE M; HOFFER M. Glutathione and thiolated chitosan inhibit multidrug resistance P-glycoprotein activity in excised small intestine. J. Control. Release., v. 111, p. 41-6, 2006.
-
(2006)
J. Control. Release
, vol.111
, pp. 41-46
-
-
WERLE, M.1
HOFFER, M.2
|