Evaluation of Biocoat® intestinal epithelium differentiation environment (3-day cultured Caco-2 cells) as an absorption screening model with improved productivity

Pharmaceutical Research

Volumn 14, Issue 12, 1997, Pages 1830-1834

  Chong, Saeho ^a   Dando, Sandra A ^b   Morrison, Richard A ^b  

^a BRISTOL MYERS SQUIBB   (United States)

^b NONE

Author keywords

Biocoat intestinal epithelium differentiation environment; Caco 2 cells; In vitro epithelial model

Indexed keywords

5 BROMOURACIL DERIVATIVE; ACETBUTALOL; ATENOLOL; CAFFEINE; CARBON 14; DESIPRAMINE; DRUG; GUANABENZ; HYDRALAZINE; IBUPROFEN; INULIN; KETOCONAZOLE; LOSARTAN; MANNITOL; METHOXYINULIN; NADOLOL; PARACETAMOL; PRAVASTATIN; PROPRANOLOL; SALICYLIC ACID; TERBUTALINE; UNCLASSIFIED DRUG;

ARTICLE; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; INTESTINE EPITHELIUM; MONOLAYER CULTURE; PRIORITY JOURNAL; PRODUCTIVITY; SCREENING; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; COMPARATIVE STUDY; CULTURE MEDIUM; DRUG SCREENING; METABOLISM; METHODOLOGY; PHARMACOKINETICS;

CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; CULTURE MEDIA; DRUG EVALUATION, PRECLINICAL; HUMANS; INTESTINAL ABSORPTION; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS;

EID: 0031422699     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012160703533     Document Type: Article

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