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Volumn 221, Issue 1-2, 2001, Pages 87-94

Development of a new system for prediction of drug absorption that takes into account drug dissolution and pH change in the gastro-intestinal tract

(5) Kobayashi, Michiya a Sada, Noriaki a Sugawara, Mitsuru a Iseki, Ken a Miyazaki, Katsumi a

a HOKKAIDO UNIVERSITY HOSPITAL (Japan)

Author keywords

Caco 2; Human; Intestinal absorption; Prediction; Screening

Indexed keywords

ALBENDAZOLE; CAFFEINE; CEFDINIR; CIMETIDINE; ENOXACIN; ESCAZOL; LEVOFLOXACIN; METOPROLOL; OZAGREL; POLYMER; RANITIDINE; RITODRINE; THEOPHYLLINE;

ARTICLE; CELL STRAIN CACO 2; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG FORMULATION; DRUG PENETRATION; DRUG SCREENING; DRUG SOLUBILITY; GASTROINTESTINAL TRACT; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; PH; PREDICTION; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; CACO-2 CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; HYDROGEN-ION CONCENTRATION; INTESTINAL ABSORPTION; PHARMACOKINETICS; PREDICTIVE VALUE OF TESTS; SOLUBILITY;

EID: 0035912914 PISSN: 03785173 EISSN: None Source Type: Journal
DOI: 10.1016/S0378-5173(01)00663-9 Document Type: Article

Times cited : (94)

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