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Volumn 290, Issue 3, 1999, Pages 1212-1221

A conditionally immortalized epithelial cell line for studies of intestinal drug transport

Author keywords

[No Author keywords available]

Indexed keywords

ALPRENOLOL; ATENOLOL; FOSCARNET; LACTULOSE; METOLAZONE; METOPROLOL TARTRATE; OLSALAZINE; PHENAZONE;

EID: 0032773855     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (77)

References (36)
  • 1
    • 0029062132 scopus 로고
    • cAMP-mediated signals as determinants for apoptosis in primary granulosa cells
    • Aharoni D, Dantes A, Oren M and Amsterdam A (1995) cAMP-mediated signals as determinants for apoptosis in primary granulosa cells. Exp Cell Res 218:271-282.
    • (1995) Exp Cell Res , vol.218 , pp. 271-282
    • Aharoni, D.1    Dantes, A.2    Oren, M.3    Amsterdam, A.4
  • 2
    • 0025311288 scopus 로고
    • Epithelial transport of drugs in cell culture. I. A model for studying the passive diffusion of drugs over intestinal absorptive (Caco-2) cells
    • Artursson P (1990) Epithelial transport of drugs in cell culture. I. A model for studying the passive diffusion of drugs over intestinal absorptive (Caco-2) cells. J Pharm Sci 79:476-482.
    • (1990) J Pharm Sci , vol.79 , pp. 476-482
    • Artursson, P.1
  • 3
    • 0031413702 scopus 로고    scopus 로고
    • Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond
    • Artursson P and Borchardt RT (1997) Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond. Pharm Res 14:1655-1658.
    • (1997) Pharm Res , vol.14 , pp. 1655-1658
    • Artursson, P.1    Borchardt, R.T.2
  • 4
    • 0025804183 scopus 로고
    • Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells
    • Artursson P and Karlsson J (1991) Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells. Biochem Biophys Res Commun 175:880-885.
    • (1991) Biochem Biophys Res Commun , vol.175 , pp. 880-885
    • Artursson, P.1    Karlsson, J.2
  • 6
    • 0027312774 scopus 로고
    • Selective paracellular permeability in two models of intestinal absorption: Cultured monolayers of human intestinal epithelial cells and rat intestinal segments
    • Artursson P, Ungell AL and Löfroth JE (1993) Selective paracellular permeability in two models of intestinal absorption: Cultured monolayers of human intestinal epithelial cells and rat intestinal segments. Pharm Res 10:1123-1129.
    • (1993) Pharm Res , vol.10 , pp. 1123-1129
    • Artursson, P.1    Ungell, A.L.2    Löfroth, J.E.3
  • 7
    • 0025775541 scopus 로고
    • Isolation, characterization and attachment of rabbit distal colon epithelial cells
    • Benya RV, Schmidt LN, Sahi J, Layden TJ and Rao MC (1991) Isolation, characterization and attachment of rabbit distal colon epithelial cells. Gastroenterology 101:692-702.
    • (1991) Gastroenterology , vol.101 , pp. 692-702
    • Benya, R.V.1    Schmidt, L.N.2    Sahi, J.3    Layden, T.J.4    Rao, M.C.5
  • 8
    • 0017410222 scopus 로고
    • Measurements of intestinal permeability using low molecular weight polyethylene glycols (PEG 400). II. Application to normal and abnormal permeability states in man and animals
    • Chadwick VS, Phillips SF and Hofmann AF (1977) Measurements of intestinal permeability using low molecular weight polyethylene glycols (PEG 400). II. Application to normal and abnormal permeability states in man and animals. Gastroenterology 73:247-251.
    • (1977) Gastroenterology , vol.73 , pp. 247-251
    • Chadwick, V.S.1    Phillips, S.F.2    Hofmann, A.F.3
  • 9
    • 0030030387 scopus 로고    scopus 로고
    • Comparison of HT29-18-C1 and Caco-2 cell lines as models for studying intestinal paracellular drug absorption
    • Collett A, Sims E, Walker D, He YL, Ayrton J, Rowland M and Warhurst G (1996) Comparison of HT29-18-C1 and Caco-2 cell lines as models for studying intestinal paracellular drug absorption. Pharm Res 13:216-221.
    • (1996) Pharm Res , vol.13 , pp. 216-221
    • Collett, A.1    Sims, E.2    Walker, D.3    He, Y.L.4    Ayrton, J.5    Rowland, M.6    Warhurst, G.7
  • 10
    • 0000811506 scopus 로고
    • Mechanics and thermodynamics of transcapillary exchange
    • (Renkin E and Michel C eds) American Physiological Society, Bethesda
    • Curry F (1984) Mechanics and thermodynamics of transcapillary exchange, in Handbook of Physiology (Renkin E and Michel C eds) pp 309-374, American Physiological Society, Bethesda.
    • (1984) Handbook of Physiology , pp. 309-374
    • Curry, F.1
  • 11
    • 0030826965 scopus 로고    scopus 로고
    • Comparison of permeability characteristics of the human colonic Caco-2 and rat small intestinal IEC-18 cell lines
    • Duizer E, Penninks AH, Stenhuis WH and Groten JP (1997) Comparison of permeability characteristics of the human colonic Caco-2 and rat small intestinal IEC-18 cell lines. J Control Release 49:39-49.
    • (1997) J Control Release , vol.49 , pp. 39-49
    • Duizer, E.1    Penninks, A.H.2    Stenhuis, W.H.3    Groten, J.P.4
  • 12
    • 0025071701 scopus 로고
    • Immortalisation and neoplastic transformation of foetal rat intestinal epithelial cells: Morphological and cytogenetic analysis, protooncogene expression and effect of gamma-interferon on cell growth
    • Emami S, Chastre E, Nizard S, Di Gioia Y, Barbu V, Taillemite JL, Ito S and Gespach C (1990) Immortalisation and neoplastic transformation of foetal rat intestinal epithelial cells: Morphological and cytogenetic analysis, protooncogene expression and effect of gamma-interferon on cell growth. Digestion 46 (Suppl 2):74-91.
    • (1990) Digestion , vol.46 , Issue.SUPPL. 2 , pp. 74-91
    • Emami, S.1    Chastre, E.2    Nizard, S.3    Di Gioia, Y.4    Barbu, V.5    Taillemite, J.L.6    Ito, S.7    Gespach, C.8
  • 13
    • 0026724311 scopus 로고
    • Structure and function of simian virus 40 large tumor antigen
    • Fanning E and Knippers R (1992) Structure and function of simian virus 40 large tumor antigen. Annu Rev Biochem 61:55-85.
    • (1992) Annu Rev Biochem , vol.61 , pp. 55-85
    • Fanning, E.1    Knippers, R.2
  • 14
    • 0028903847 scopus 로고
    • Effect of changing intestinal flow rate on a measurement of intestinal permeability
    • Fine KD, Santa Ana CA, Porter JL and Fordtran JS (1995) Effect of changing intestinal flow rate on a measurement of intestinal permeability. Gastroenterology 108:983-989.
    • (1995) Gastroenterology , vol.108 , pp. 983-989
    • Fine, K.D.1    Santa Ana, C.A.2    Porter, J.L.3    Fordtran, J.S.4
  • 15
    • 0021490671 scopus 로고
    • Epithelial properties of human colonic carcinoma cell line Caco-2: Electrical parameters
    • Grasset E, Pinto M, Dussaulx E, Zweibaum A and Desjeux JF (1984) Epithelial properties of human colonic carcinoma cell line Caco-2: Electrical parameters. Am J Physiol 247:C260-267.
    • (1984) Am J Physiol , vol.247
    • Grasset, E.1    Pinto, M.2    Dussaulx, E.3    Zweibaum, A.4    Desjeux, J.F.5
  • 16
    • 0027411562 scopus 로고
    • Active secretion of the fluoroquinolone ciprofloxacin by human intestinal epithelial Caco-2 cell layers
    • Griffiths NM, Hirst BH and Simmons NL (1993) Active secretion of the fluoroquinolone ciprofloxacin by human intestinal epithelial Caco-2 cell layers. Br J Pharmacol 108:575-576.
    • (1993) Br J Pharmacol , vol.108 , pp. 575-576
    • Griffiths, N.M.1    Hirst, B.H.2    Simmons, N.L.3
  • 17
    • 0024592630 scopus 로고
    • Cell lines established by a temperature-sensitive simian virus 40 large-T-antigen gene are growth restricted at the nonpermissive temperature
    • Jat PS and Sharp PA (1989) Cell lines established by a temperature-sensitive simian virus 40 large-T-antigen gene are growth restricted at the nonpermissive temperature. Mol Cell Biol 9:1672-1681.
    • (1989) Mol Cell Biol , vol.9 , pp. 1672-1681
    • Jat, P.S.1    Sharp, P.A.2
  • 18
    • 0002169455 scopus 로고
    • Amino acid arylamidase
    • (Beergmeyer H ed) Verlag Chemie, Weinheim
    • Joannes CM and Hafkenscheid M (1984) Amino acid arylamidase, in Methods of Enzymatic Analysis (Beergmeyer H ed) pp 11-15, Verlag Chemie, Weinheim.
    • (1984) Methods of Enzymatic Analysis , pp. 11-15
    • Joannes, C.M.1    Hafkenscheid, M.2
  • 19
    • 0027146389 scopus 로고
    • Transport of celiprolol across human intestinal epithelial (Caco-2) cells: Mediation of secretion by multiple transporters including P-glycoprotein
    • Karlsson J, Kuo SM, Ziemniak J and Artursson P (1993) Transport of celiprolol across human intestinal epithelial (Caco-2) cells: Mediation of secretion by multiple transporters including P-glycoprotein. Br J Pharmacol 110:1009-1016.
    • (1993) Br J Pharmacol , vol.110 , pp. 1009-1016
    • Karlsson, J.1    Kuo, S.M.2    Ziemniak, J.3    Artursson, P.4
  • 20
    • 0020393263 scopus 로고
    • Evaluation of mannitol for use as a probe marker of gastrointestinal permeability in man
    • Laker MF, Bull HJ and Menzies IS (1982) Evaluation of mannitol for use as a probe marker of gastrointestinal permeability in man. Eur J Clin Invest 12:485-491.
    • (1982) Eur J Clin Invest , vol.12 , pp. 485-491
    • Laker, M.F.1    Bull, H.J.2    Menzies, I.S.3
  • 21
    • 0030905160 scopus 로고    scopus 로고
    • Jejunal permeability: A comparison between the ussing chamber technique and the single-pass perfusion in humans
    • Lennernäs H, Nylander S and Ungell AL (1997) Jejunal permeability: A comparison between the ussing chamber technique and the single-pass perfusion in humans. Pharm Res 14:667-671.
    • (1997) Pharm Res , vol.14 , pp. 667-671
    • Lennernäs, H.1    Nylander, S.2    Ungell, A.L.3
  • 22
    • 0030023536 scopus 로고    scopus 로고
    • Comparison between active and passive drug transport in human intestinal epithelial (Caco-2) cells in 0itro and human jejunum in vivo
    • Lennernäs H, Palm K, Fagerholm U and Artursson P (1996) Comparison between active and passive drug transport in human intestinal epithelial (Caco-2) cells in 0itro and human jejunum in vivo. Int J Pharm 127:103-107.
    • (1996) Int J Pharm , vol.127 , pp. 103-107
    • Lennernäs, H.1    Palm, K.2    Fagerholm, U.3    Artursson, P.4
  • 23
    • 0029610127 scopus 로고
    • Mechanisms of absorption enhancement by medium chain fatty acids in intestinal epithelial Caco-2 cell monolayers
    • Lindmark T, Nikkilä T and Artursson P (1995) Mechanisms of absorption enhancement by medium chain fatty acids in intestinal epithelial Caco-2 cell monolayers. J Pharmacol Exp Ther 275:958-964.
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 958-964
    • Lindmark, T.1    Nikkilä, T.2    Artursson, P.3
  • 24
    • 0031024171 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski CA, Lombardo F, Dominy BW and Feeney PJ (1997) Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Delivery Rev 23:3-25.
    • (1997) Adv Drug Delivery Rev , vol.23 , pp. 3-25
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 25
    • 0013891296 scopus 로고
    • A one-step ultramicro method for the assay of intestinal disaccharidases
    • Messier M and Dahlqvist A (1966) A one-step ultramicro method for the assay of intestinal disaccharidases. Anal Biochem 14:376-392.
    • (1966) Anal Biochem , vol.14 , pp. 376-392
    • Messier, M.1    Dahlqvist, A.2
  • 27
    • 0032585545 scopus 로고    scopus 로고
    • Evaluation of dynamic polar molecular surface area as predictor of drug absorption: Comparison with other computational and experimental predictors
    • Palm K, Luthman K, Ungell AL, Strandlund G, Beigi F, Lundahl P and Artursson P (1998) Evaluation of dynamic polar molecular surface area as predictor of drug absorption: Comparison with other computational and experimental predictors. J Med Chem 41:5382-5392.
    • (1998) J Med Chem , vol.41 , pp. 5382-5392
    • Palm, K.1    Luthman, K.2    Ungell, A.L.3    Strandlund, G.4    Beigi, F.5    Lundahl, P.6    Artursson, P.7
  • 28
    • 0030914681 scopus 로고    scopus 로고
    • Polar molecular surface properties predict the intestinal absorption of drugs in humans
    • Palm K, Stenberg P, Luthman K and Artursson P (1997) Polar molecular surface properties predict the intestinal absorption of drugs in humans. Pharm Res 14: 568-571.
    • (1997) Pharm Res , vol.14 , pp. 568-571
    • Palm, K.1    Stenberg, P.2    Luthman, K.3    Artursson, P.4
  • 29
    • 0027325809 scopus 로고
    • Conditionally immortalized intestinal epithelial cells. Novel approach for study of differentiated enterocytes
    • Paul ECA, Hochman J and Quaroni A (1993) Conditionally immortalized intestinal epithelial cells. Novel approach for study of differentiated enterocytes. Am J Physiol 265:C266-C278.
    • (1993) Am J Physiol , vol.265
    • Paul, E.C.A.1    Hochman, J.2    Quaroni, A.3
  • 30
    • 0002833727 scopus 로고
    • Intestinal water and electrolyte transport
    • (Johnson LR ed) Raven Press, New York
    • Powell D (1987) Intestinal water and electrolyte transport, in Physiology of the Gastrointestinal Tract (Johnson LR ed) pp 1267-1305, Raven Press, New York.
    • (1987) Physiology of the Gastrointestinal Tract , pp. 1267-1305
    • Powell, D.1
  • 31
    • 0030870173 scopus 로고    scopus 로고
    • Cell dynamics and differentiation of conditionally immortalized human intestinal epithelial cells
    • Quaroni A and Beaulieu JF (1997) Cell dynamics and differentiation of conditionally immortalized human intestinal epithelial cells. Gastroenterology 113:1198-1213.
    • (1997) Gastroenterology , vol.113 , pp. 1198-1213
    • Quaroni, A.1    Beaulieu, J.F.2
  • 32
    • 0030588649 scopus 로고    scopus 로고
    • Development of intestinal cell culture models for drug transport and metabolism studies
    • Quaroni A and Hochman J (1996) Development of intestinal cell culture models for drug transport and metabolism studies. Adv Drug Delivery Rev 22:3-52.
    • (1996) Adv Drug Delivery Rev , vol.22 , pp. 3-52
    • Quaroni, A.1    Hochman, J.2
  • 33
    • 0031780252 scopus 로고    scopus 로고
    • Jejunal absorption and metabolism of R/S-verapamil in humans
    • Sandström R, Karlsson A, Knutson L and Lennernäs H (1998) Jejunal absorption and metabolism of R/S-verapamil in humans. Pharm Res 15:856-862.
    • (1998) Pharm Res , vol.15 , pp. 856-862
    • Sandström, R.1    Karlsson, A.2    Knutson, L.3    Lennernäs, H.4
  • 34
    • 0029090391 scopus 로고
    • Co-cultures of human intestinal goblet (HT29-H) and absorptive (Caco-2) cells for studies on 0pithelial transport and integrity
    • Wikman Larhed A and Artursson P (1995) Co-cultures of human intestinal goblet (HT29-H) and absorptive (Caco-2) cells for studies on 0pithelial transport and integrity. Eur J Pharm Sci 3:171-183.
    • (1995) Eur J Pharm Sci , vol.3 , pp. 171-183
    • Wikman Larhed, A.1    Artursson, P.2
  • 35
    • 0028113469 scopus 로고
    • Differentiated intestinal epithelial cell lines as in vitro models for predicting the intestinal absorption of drugs
    • Wils P, Warnery A, Phung-Ba V and Scherman D (1994) Differentiated intestinal epithelial cell lines as in vitro models for predicting the intestinal absorption of drugs. Cell Biol Toxicol 10:393-397.
    • (1994) Cell Biol Toxicol , vol.10 , pp. 393-397
    • Wils, P.1    Warnery, A.2    Phung-Ba, V.3    Scherman, D.4
  • 36
    • 0028306624 scopus 로고
    • Apoptosis is induced at nonpermissive temperature by a transient increase in p53 in cell lines immortalized with temperature-sensitive SV40 large T-antigen gene
    • Yanai N and Obinata M (1994) Apoptosis is induced at nonpermissive temperature by a transient increase in p53 in cell lines immortalized with temperature-sensitive SV40 large T-antigen gene. Exp Cell Res 211:296-300.
    • (1994) Exp Cell Res , vol.211 , pp. 296-300
    • Yanai, N.1    Obinata, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.