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Volumn 51, Issue 5, 2008, Pages 1402-1405

Strongylophorines: Natural product inhibitors of hypoxia-inducible factor-1 transcriptional pathway

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BIOLOGICAL PRODUCT; HYPOXIA INDUCIBLE FACTOR 1; STRONGLYPHORINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 41649084741     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm7010854     Document Type: Article
Times cited : (34)

References (30)
  • 1
    • 0028242772 scopus 로고
    • Measurement of human tumor oxygenation status by a polarographic needle electrode. An analysis of inter and intratumour heterogeneity
    • Nordsmark, M.; Bentzel, S. M.; Overgaard, J. Measurement of human tumor oxygenation status by a polarographic needle electrode. An analysis of inter and intratumour heterogeneity. Acta Oncol. 1994, 33, 383-389.
    • (1994) Acta Oncol , vol.33 , pp. 383-389
    • Nordsmark, M.1    Bentzel, S.M.2    Overgaard, J.3
  • 2
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia - a key regulatory factor in tumour growth
    • Harris, A. L. Hypoxia - a key regulatory factor in tumour growth. Nat. Rev. Cancer 2002, 2, 38-47.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 4
    • 0029753768 scopus 로고    scopus 로고
    • Genetic instability induced by the tumor microenvironment
    • Reynolds, T. Y.; Rockwell, S.; Glazer, P. M. Genetic instability induced by the tumor microenvironment. Cancer Res. 1996, 56, 5754-5757.
    • (1996) Cancer Res , vol.56 , pp. 5754-5757
    • Reynolds, T.Y.1    Rockwell, S.2    Glazer, P.M.3
  • 5
    • 0026468180 scopus 로고
    • A nuclear factor induced by hypoxia via de novo protein synthesis binds to human erythropoietin gene enhancer at a site required for transcriptional activation
    • Semenza, G. L.; Wang, G. L. A nuclear factor induced by hypoxia via de novo protein synthesis binds to human erythropoietin gene enhancer at a site required for transcriptional activation. Mol. Cell. Biol. 1992, 12, 5447-5454.
    • (1992) Mol. Cell. Biol , vol.12 , pp. 5447-5454
    • Semenza, G.L.1    Wang, G.L.2
  • 6
    • 0027427588 scopus 로고
    • Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia
    • Semenza, G. L.; Wang, G. L. Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia. J. Biol. Chem. 1993, 268, 21513-21518.
    • (1993) J. Biol. Chem , vol.268 , pp. 21513-21518
    • Semenza, G.L.1    Wang, G.L.2
  • 7
    • 0028816847 scopus 로고
    • Purification and characterization of hypoxia-inducible factor 1
    • Semenza, G. L.; Wang, G. L. Purification and characterization of hypoxia-inducible factor 1. J. Biol. Chem. 1995, 270, 1230-1237.
    • (1995) J. Biol. Chem , vol.270 , pp. 1230-1237
    • Semenza, G.L.1    Wang, G.L.2
  • 8
    • 0032053169 scopus 로고    scopus 로고
    • Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression
    • Ratcliffe, P. J.; O'Rourke, J. F.; Maxwell, P. H.; Pugh, C. W. Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression. J. Exp. Biol. 1998, 201, 1153-1162.
    • (1998) J. Exp. Biol , vol.201 , pp. 1153-1162
    • Ratcliffe, P.J.1    O'Rourke, J.F.2    Maxwell, P.H.3    Pugh, C.W.4
  • 9
    • 0031823016 scopus 로고    scopus 로고
    • The molecular basis of the hypoxia response pathway: Tumour hypoxia as a therapy target
    • Blancher, C.; Harris, A. L. The molecular basis of the hypoxia response pathway: tumour hypoxia as a therapy target. Cancer Metastasis Rev. 1998, 17, 187-194.
    • (1998) Cancer Metastasis Rev , vol.17 , pp. 187-194
    • Blancher, C.1    Harris, A.L.2
  • 10
    • 2542560545 scopus 로고    scopus 로고
    • Molecular-targeted antitumor agents: The Saururus cernuus dineolignans manassantin B and 4-O-demethylmanassantin B are potent inhibitors of hypoxia-activated HIF-1
    • Hodges, T.; Hossain, C.; Kim, Y-P.; Zhou, Y-D.; Nagle, D. G. Molecular-targeted antitumor agents: the Saururus cernuus dineolignans manassantin B and 4-O-demethylmanassantin B are potent inhibitors of hypoxia-activated HIF-1. J. Nat. Prod. 2004, 67, 767-771.
    • (2004) J. Nat. Prod , vol.67 , pp. 767-771
    • Hodges, T.1    Hossain, C.2    Kim, Y.-P.3    Zhou, Y.-D.4    Nagle, D.G.5
  • 11
    • 11844270484 scopus 로고    scopus 로고
    • Laurenditerpenol, a new diterpene from the tropical marine alga Laurencia intricata that potently inhibits HIF-1 mediated hypoxic signaling in breast tumor cells
    • Mohammed, K. A.; Hossain, C. F.; Zhang, L.; Bruick, R. K.; Zhou, Y-D.; Nagle, D. G. Laurenditerpenol, a new diterpene from the tropical marine alga Laurencia intricata that potently inhibits HIF-1 mediated hypoxic signaling in breast tumor cells. J. Nat. Prod. 2004, 67, 2002-2007.
    • (2004) J. Nat. Prod , vol.67 , pp. 2002-2007
    • Mohammed, K.A.1    Hossain, C.F.2    Zhang, L.3    Bruick, R.K.4    Zhou, Y.-D.5    Nagle, D.G.6
  • 13
    • 11144239579 scopus 로고    scopus 로고
    • 2 - Methoxyestradiol inhibits hypoxia-inducible factor 1 alpha tumor growth, and angiogenesis and augments paclitaxel efficacy in head and neck squamous cell carcinoma
    • Ricker, J. L.; Chen, Z.; Yang, X. P.; Pribluda, V. S.; Swartz, G. M.; Van Waes, C. 2 - Methoxyestradiol inhibits hypoxia-inducible factor 1 alpha tumor growth, and angiogenesis and augments paclitaxel efficacy in head and neck squamous cell carcinoma. Clin. Cancer Res. 2004, 10, 8665-8673.
    • (2004) Clin. Cancer Res , vol.10 , pp. 8665-8673
    • Ricker, J.L.1    Chen, Z.2    Yang, X.P.3    Pribluda, V.S.4    Swartz, G.M.5    Van Waes, C.6
  • 14
    • 0036682284 scopus 로고    scopus 로고
    • Rapisarda, A.; Uranchimeg, B.; Scudiero, D. A.; Selby, M.; Sausville, E. A; Shoemaker, R. H.; Melillo, G. Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway. Cancer Res. 2002, 62, 4316-4324.
    • Rapisarda, A.; Uranchimeg, B.; Scudiero, D. A.; Selby, M.; Sausville, E. A; Shoemaker, R. H.; Melillo, G. Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway. Cancer Res. 2002, 62, 4316-4324.
  • 15
    • 4444369682 scopus 로고    scopus 로고
    • Antitumor activity and pharmacodynamic properties of PX-478, an inhibitor of hypoxia-inducible factor-1α
    • Welsh, S.; Williams, R.; Kirkpatrick, D. L.; Paine-Murrieta, G.; Powis, G. Antitumor activity and pharmacodynamic properties of PX-478, an inhibitor of hypoxia-inducible factor-1α. Mol.Cancer Ther. 2004, 3, 233-244.
    • (2004) Mol.Cancer Ther , vol.3 , pp. 233-244
    • Welsh, S.1    Williams, R.2    Kirkpatrick, D.L.3    Paine-Murrieta, G.4    Powis, G.5
  • 16
    • 4444311880 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1α as a cancer drug target
    • Powis, G.; Kirkpatrick, D. L. Hypoxia inducible factor-1α as a cancer drug target. Mol. Cancer Ther. 2004, 3, 647-654.
    • (2004) Mol. Cancer Ther , vol.3 , pp. 647-654
    • Powis, G.1    Kirkpatrick, D.L.2
  • 17
    • 23244454418 scopus 로고    scopus 로고
    • New drugs target hypoxia response in tumors
    • Garber, K. New drugs target hypoxia response in tumors. J. Natl. Cancer Inst. 2005, 97, 1112-1114.
    • (2005) J. Natl. Cancer Inst , vol.97 , pp. 1112-1114
    • Garber, K.1
  • 18
    • 34247109045 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the last 25 years
    • Newman, D. J.; Cragg, G. M. Natural products as sources of new drugs over the last 25 years. J. Nat. Prod. 2007, 70, 461-477.
    • (2007) J. Nat. Prod , vol.70 , pp. 461-477
    • Newman, D.J.1    Cragg, G.M.2
  • 19
    • 1842450526 scopus 로고    scopus 로고
    • Punaglandins, chlorinated prostaglandins, function as potent Michael receptors to inhibit ubiquitin isopeptidase activity
    • Verbitski, S. M.; Mullally, J. E.; Fitzpatrick, F. A.; Ireland, C. M. Punaglandins, chlorinated prostaglandins, function as potent Michael receptors to inhibit ubiquitin isopeptidase activity. J. Med. Chem. 2004, 47, 2067-2070.
    • (2004) J. Med. Chem , vol.47 , pp. 2067-2070
    • Verbitski, S.M.1    Mullally, J.E.2    Fitzpatrick, F.A.3    Ireland, C.M.4
  • 20
    • 2942631728 scopus 로고    scopus 로고
    • Naamidine A intensifies the phosphotransferase activity of extracellular signal-regulated kinases causing A-431 cells to arrest in G1
    • James, R. D.; Jones, D. A.; Aalbersberg, W.; Ireland, C. M. Naamidine A intensifies the phosphotransferase activity of extracellular signal-regulated kinases causing A-431 cells to arrest in G1. Mol. Cancer Ther. 2003, 2, 747-751.
    • (2003) Mol. Cancer Ther , vol.2 , pp. 747-751
    • James, R.D.1    Jones, D.A.2    Aalbersberg, W.3    Ireland, C.M.4
  • 22
    • 84984198723 scopus 로고
    • Chemical studies of marine invertebrates. XXXVII. Three novel meroditerpenoids from the sponge Strongylophora durissima
    • Braekman, J. C.; Daloze, D.; Hulot, G.; Tursch, B.; Declercq, J. P.; Germain, G.; Van Meerssche, M. Chemical studies of marine invertebrates. XXXVII. Three novel meroditerpenoids from the sponge Strongylophora durissima. Bull. Soc. Chim. Belg. 1978, 87, 917-926.
    • (1978) Bull. Soc. Chim. Belg , vol.87 , pp. 917-926
    • Braekman, J.C.1    Daloze, D.2    Hulot, G.3    Tursch, B.4    Declercq, J.P.5    Germain, G.6    Van Meerssche, M.7
  • 23
    • 0000099314 scopus 로고
    • Metabolites of the sponge Strongylophora durissima from Maricaban Island, Philippines
    • Salva, J.; Faulkner, D. J. Metabolites of the sponge Strongylophora durissima from Maricaban Island, Philippines. J. Org. Chem. 1990, 55, 1941-1943.
    • (1990) J. Org. Chem , vol.55 , pp. 1941-1943
    • Salva, J.1    Faulkner, D.J.2
  • 24
    • 0031927695 scopus 로고    scopus 로고
    • A new meroditerpenoid dimer from an undescribed Philippine marine sponge of the genus Strongylophora
    • Balbin-Oliveros, M.; Edrada, R.; Proksch, P.; Wray, V.; Witte, W. M.; Van Soest, R. W. M. A new meroditerpenoid dimer from an undescribed Philippine marine sponge of the genus Strongylophora. J. Nat. Prod. 1998, 61, 948-952.
    • (1998) J. Nat. Prod , vol.61 , pp. 948-952
    • Balbin-Oliveros, M.1    Edrada, R.2    Proksch, P.3    Wray, V.4    Witte, W.M.5    Van Soest, R.W.M.6
  • 25
    • 21344467001 scopus 로고    scopus 로고
    • Seven new meroditerpenoids, from the marine sponge Strongylophora strongylata, that inhibited the maturation of starfish oocytes
    • Liu, H.; Namikoshi, M.; Akano, K.; Kobayashi, H.; Nagai, H.; Yao, X. Seven new meroditerpenoids, from the marine sponge Strongylophora strongylata, that inhibited the maturation of starfish oocytes. J. Asian Nat. Prod. Res. 2005, 7, 661-670.
    • (2005) J. Asian Nat. Prod. Res , vol.7 , pp. 661-670
    • Liu, H.1    Namikoshi, M.2    Akano, K.3    Kobayashi, H.4    Nagai, H.5    Yao, X.6
  • 26
    • 4344657965 scopus 로고    scopus 로고
    • Strongylophorine-26, a new meroditerpenoid isolated from the marine sponge Petrosia (Strongylophora) corticata that exhibits anti-invasion activity
    • Warabi, K.; McHardy, L. M.; Matainaho, L.; Van Soest, R. W. M.; Roskelley, C. D.; Roberge, M.; Andersen, R. J. Strongylophorine-26, a new meroditerpenoid isolated from the marine sponge Petrosia (Strongylophora) corticata that exhibits anti-invasion activity. J. Nat. Prod. 2004, 67, 1387-1389.
    • (2004) J. Nat. Prod , vol.67 , pp. 1387-1389
    • Warabi, K.1    McHardy, L.M.2    Matainaho, L.3    Van Soest, R.W.M.4    Roskelley, C.D.5    Roberge, M.6    Andersen, R.J.7
  • 29
    • 0041349558 scopus 로고    scopus 로고
    • The relevance of cell proliferation, vascular endothelial growth factor and basic fibroblast growth factor production to angiogenesis and tumori-genicity in human glioma cell lines
    • Ke, L. D.; Shi, Y. X.; Im, S. A.; Chen, X.; Yung, W. K. The relevance of cell proliferation, vascular endothelial growth factor and basic fibroblast growth factor production to angiogenesis and tumori-genicity in human glioma cell lines. Clin. Can. Res. 2000, 6, 2562-2572.
    • (2000) Clin. Can. Res , vol.6 , pp. 2562-2572
    • Ke, L.D.1    Shi, Y.X.2    Im, S.A.3    Chen, X.4    Yung, W.K.5
  • 30
    • 0029761644 scopus 로고    scopus 로고
    • Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
    • Forsythe, J. A.; Jiang, B. H.; Iyer, N. V.; Agani, F.; Leung, S. W.; Koos, R. D.; Semenza, G. L. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol. Cell. Biol. 1996, 16, 4604-4613.
    • (1996) Mol. Cell. Biol , vol.16 , pp. 4604-4613
    • Forsythe, J.A.1    Jiang, B.H.2    Iyer, N.V.3    Agani, F.4    Leung, S.W.5    Koos, R.D.6    Semenza, G.L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.