Laurenditerpenol, a new diterpene from the tropical marine alga Laurencia intricata that potently inhibits HIF-1 mediated hypoxic signaling in breast tumor cells

Journal of Natural Products

Volumn 67, Issue 12, 2004, Pages 2002-2007

  Mohammed, Kaleem A ^a   Hossain, Chowdhury Faiz ^a,b   Zhang, Lei ^c   Bruick, Richard K ^c   Zhou, Yu Dong ^a,b   Nagle, Dale G ^a  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DITERPENE; HYPOXIA INDUCIBLE FACTOR 1; IRON CHELATING AGENT; LAURENDITERPENOL; UNCLASSIFIED DRUG; VASCULOTROPIN;

ARTICLE; BIOASSAY; BREAST TUMOR; CANCER INHIBITION; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG INHIBITION; DRUG STRUCTURE; FRACTIONATION; HUMAN; HUMAN CELL; HYPOXIA; LAURENCIA; MITOCHONDRIAL RESPIRATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; OXYGEN CONSUMPTION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; SPECTROSCOPY; TUMOR CELL; TUMOR CELL LINE;

ALGAE, RED; ANOXIA; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; DITERPENES; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MITOCHONDRIA; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEAR PROTEINS; STEREOISOMERISM; TRANSCRIPTION FACTORS;

ALGAE; EUKARYOTA; LAURENCIA; LAURENCIA INTRICATA; RHODOPHYTA;

EID: 11844270484     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np049753f     Document Type: Article

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