Improved antioxidant effect of idebenone-loaded polyethyl-2-cyanoacrylate nanocapsules tested on human fibroblasts

Pharmaceutical Research

Volumn 19, Issue 1, 2002, Pages 71-78

  Palumbo, M ^a   Russo, A ^a   Cardile, V ^a   Renis, M ^a   Paolino, D ^a   Puglisi, G ^a   Fresta, M ^b  

^a UNIVERSITY OF CATANIA   (Italy)

^b Department of Pharmacobiological Sciences   (Italy)

Author keywords

Antiapoptotic effect; COMET assay; Free radical induced damage; Idebenone; Oxidative stress; PECA nanocapsules

Indexed keywords

CASPASE 3; CELL NUCLEUS DNA; HYDROGEN PEROXIDE; IDEBENONE; MALEIC ACID DIETHYL ESTER; NANOCAPSULE; POLY(ETHYL 2 CYANOACRYLATE); POLYSORBATE 80; REACTIVE OXYGEN METABOLITE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DRUG EFFECT; DRUG FORMULATION; DRUG STRUCTURE; ENZYME ACTIVITY; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; OXIDATIVE STRESS; POLYMERIZATION; PRIORITY JOURNAL;

EID: 0036147315     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1013659516878     Document Type: Article

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