Melatonin: Its intracellular and genomic actions

Trends in Endocrinology and Metabolism

Volumn 7, Issue 1, 1996, Pages 22-27

  Reiter, Russel J ^a   Oh, Chang Seok ^a   Fujimori, Osamu ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; BUTHIONINE SULFOXIMINE; CARBON TETRACHLORIDE; FREE RADICAL; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; LIPOPOLYSACCHARIDE; MELATONIN; MELATONIN RECEPTOR; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SAFROLE; SCAVENGER; SINGLET OXYGEN;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; BINDING SITE; CATARACTOGENESIS; CONTROLLED STUDY; DNA DAMAGE; GENE EXPRESSION REGULATION; GENOME; HORMONE ACTION; HUMAN; HUMAN CELL; IONIZING RADIATION; LIGHT DARK CYCLE; LIPID PEROXIDATION; MEMBRANE BINDING; NEUROENDOCRINOLOGY; NEWBORN; NONHUMAN; PINEAL BODY; PRIORITY JOURNAL; RAT; SHORT SURVEY; TRANSCRIPTION REGULATION;

EID: 0030047670     PISSN: 10432760     EISSN: None     Source Type: Journal    
DOI: 10.1016/1043-2760(95)00192-1     Document Type: Short Survey

References (41)

1. Abe M, Reiter RJ, Orhii PB, Hara M, Poeggeler B: 1994. Inhibitory effect of melatonin on cataract formation in newborn rats: evidence for an antioxidant role for melatonin. J Pineal Res 17:94-100.
2. Acuña-Castroviejo D, Reiter RJ, Menendez-Pelaez A, Pablos MI, Burgos A: 1994. Characterization of high affinity melatonin binding sites in purified cell nuclei of rat liver. J Pineal Res 16:100-113.
3. Barlow-Walden LR, Reiter RJ, Abe M, et al.: 1995. Melatonin stimulates brain glutathione peroxidase activity. Neurochem Int 26:497-502.
4. Becker-Andre M, Wisenberg I, Scharren-Wiemers N, et al.: 1994. Pineal gland hormone melatonin binds and activates an orphan of the nuclear receptor superfamily. J Biol Chem 269:28,531-28,534.
5. Cagnoli CM, Atabay C, Kharlamova E, Manev E: 1995. Melatonin protects neurons from singlet oxygen-induced apoptosis. J Pineal Res 18:222-226.
6. Daniels WMU, Reiter RJ, Melchiorri D, Sewerynek E, Pablos MI, Ortiz GG: 1995. Melatonin counteracts lipid peroxidation induced by carbon tetrachloride but does not restore glucose-6-phosphatase activity. J Pineal Res 19:1-6.
7. Giusti P, Gusella M, Liparetti M, et al.: 1995. Melatonin protects primary cultures of cerebellar granule neurons from kainate but not from A'-methyl-asparate neurotoxicity. Exp Neurol 131:39-46.
8. Harman D: 1992. Free radical theory of aging. Mutat Res 275:257-266.
9. Huerto-Delgadillo L, Anton-Tay F, Benitz-King G: 1994. Effects of melatonin on microtubule assembly depend on hormone concentration: role of melatonin as a calmodulin antagonist. J Pineal Res 17:55-62.
10. Knight JA: 1995. Diseases related to oxygen-derived free radicals. Ann Clin Lab Sci 25: 111-121.
11. Kukreja RC, Loesser KE, Kearns AA, Naseem SA, Heas ML: 1993. Protective effect of histidine during ischemia-reperfusion in isolated perfused rat hearts. Am J Physiol 264: H1370-H1381.
12. Malpaux B, Daveau A, Maurice F, Locatelli A, Threry JC: 1994. Evidence that melatonin binding sites in the pars tuberalis do not mediate the photoperiodic actions of melatonin on LH and prolactin secretion in ewes. J Reprod Fertil 101:625-632.
13. Melchiorri D, Reiter RJ, Attia AM, Hara M, Burgos A, Nistico G: 1994. Potent protective effect of melatonin on in vivo paraquat-induced oxidative damage in rats. Life Sci 56:83-89.
14. Melchiorri D, Reiter RJ, Sewerynek E, Chen LD, Nistico G: 1995. Melatonin reduces kainate-induced lipid peroxidation in homogenates of different brain regions. FASEB J 9:1205-1210.
15. Menendez-Pelaez A, Rodriguez C, Dominguez D: 1991. 5-Aminolevulinate synthase mRNA levels in the Harderian gland of Syrian hamsters: correlation with porphyrin concentrations and regulation by androgens and melatonin. Mol Cell Endocrinol 80:177-182.
16. Menendez-Pelaez A, Poeggeler B, Reiter RJ, Barlow-Walden LR, Pablos MI, Tan DX: 1993. Nuclear localization of melatonin in different mammalian tissues: immunocytochemical and radioimmunoassay evidence. J Cell Biochem 53:372-382.
17. Morgan PJ, Mercer JG: 1994. Control seasonality by melatonin. Proc Nutr Soc 53:483-493.
18. Packer L: 1994. Vitamin E is nature's master antioxidant. Sci Am (Sci Technol) Mar/Apr pp 54-63.
19. Pieri C, Marra M, Moroni F, Recchioni R Marcheselli F: 1994. Melatonin: a peroxyl radical scavenger more effective than vitamin E. Life Sci 55:PL271-PL276.
20. Pierrefiche G, Laborit H: 1995. Oxygen free radicals, melatonin and aging. Exp Gerontol 30:213-227.
21. Poeggeler B, Balzer I, Hardeland R, Lerchl A 1991. Pineal hormone melatonin oscillates also in the dinoflagellate Gonyaulax polye-dra. Naturwissenschaften 78:268-269.
22. Poeggeler B, Reiter RJ, Tan DX, Chen LC Manchester LC: 1993. Melatonin, hydroxyl radical-mediated oxidative damage, and aging: a hypothesis. J Pineal Res 14:151-168.
23. Poeggeler B, Reiter RJ, Hardeland R, Sewerynek E, Melchiorri D, Barlow-Walden LR: 1995. Melatonin, a mediator of electron transfer and repair reactions, acts synergistically with the chain-breaking antioxidants ascorbate, trolox and glutathione. Neuroendocrinol Lett 17:87-92.
24. Pozo D, Reiter RJ, Calvo JP, Guerrero JM 1994. Physiological concentrations of melatonin inhibit nitric oxide synthase in rat cerebellum. Life Sci 55:PL455-PL460.
25. Reiter RJ: 1991. Pineal melatonin: cell biology of its synthesis and of its physiological interactions. Endocr Rev 12:151-180.
26. Reiter RJ: 1992. Melatonin: that ubiquitously acting pineal hormone. News Physiol Sci 6:223-227.
27. Reiter RJ: 1995a. Oxidative processes and antioxidative defense mechanisms in the aging brain. FASEB J 9:526-533.
28. Reiter RJ: 1995b. The pineal gland and melatonin in relation to aging: a summary of the theories and of the data. Exp Gerontol 30: 199-212.
29. Reiter RJ, Tan DX, Poeggeler B, Menendez-Pelaez A, Chen LD, Saarela S: 1994. Melatonin as a free radical scavenger: implications for aging and age-related diseases. Ann NY Acad Sci 719:1-12.
30. Reiter RJ, Melchiorri D, Sewerynek E, et al.: 1995. A review of the evidence supporting melatonin's role as an antioxidant. J Pineal Res 18:1-11.
31. Reppert SM, Weaver DR, Ebisawa T: 1994. Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses. Neuron 13:1177-1185.
32. Scaiano JC: 1995. Exploratory laser flash photolysis study of free radical reactions and magnetic field effects in melatonin chemistry. J Pineal Res 19:109-195.
33. Sewerynek E, Abe M, Reiter RJ, et al.: 1995a. Melatonin administration prevents lipopolysaccharide-induced oxidative damage in pentobarbital-treated animals. J Cell Biochem 58:436-444.
34. Sewerynek E, Melchiorri D, Chen LD, Reiter RJ: 1995b. Melatonin reduces both basal and lipopolysaccharide-induced lipid peroxidation in vivo. Free Radic Biol Med 19: 903-909.
35. Shida CS, Castrucci AML, Larry-Freund MT: 1994. High melatonin solubility in aqueous medium. J Pineal Res 16:198-201.
36. Steinhilber D, Brungs M, Werz O, et al.: 1995. The nuclear receptor for melatonin represses 5-lipooxygenase gene expression in human B lymphocytes. J Biol Chem 270:7037-7040.
37. Tan DX, Chen LD, Poeggeler B, Manchester LC, Reiter RJ: 1993a. Melatonin: a potent, endogenous hydroxyl radical scavenge. Endocr J 1:57-60.
38. Tan DX, Poeggeler B, Reiter RJ, et al.: 1993b. The pineal hormone melatonin inhibits DNA adduct formation induced by the chemical carcinogen safrole in vivo. Cancer Lett 70:65-71.
39. Tan DX, Reiter RJ, Chen LD, Poeggeler B, Manchester LC, Barlow-Waiden LR: 1994. Both physiological and pharmacological levels of melatonin reduce DNA adduct for-mation induced by the chemical carcinogen safrole. Carcinogenesis 15:215-218.
40. Vijayalaxmi, Reiter RJ, Sewerynek E, Poeggeler B, Leal BZ, Meltz ML: 1995. Marked reduction of radiation-induced micronuclei in human blood lymphocytes pretreated with melatonin. Radiat Res 143: 102-106.
41. Wiesenberg I, Missbach M, Kohlen JP, Schroder M, Carlberg C: 1995. Transcriptional activation of the nuclear receptor RZRγ by the pineal hormone melatonin and identification of CGP 52608 as a synthetic ligand. Nucleic Acids Res 23: 317-338.