-
1
-
-
0032499401
-
Modes of interactions between signaling pathways
-
Jordan JD, Iyengar R (1998) Modes of interactions between signaling pathways. Biochem Pharmacol 55:1347-1352.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 1347-1352
-
-
Jordan, J.D.1
Iyengar, R.2
-
2
-
-
0033001953
-
Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes
-
Fambrough D, McClure K, Kazlauskas A, Lander ES (1999) Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes. Cell 97:727-741.
-
(1999)
Cell
, vol.97
, pp. 727-741
-
-
Fambrough, D.1
McClure, K.2
Kazlauskas, A.3
Lander, E.S.4
-
3
-
-
0034644509
-
Signaling networks: The origins of cellular multitasking
-
Jordan JD, Landau EM, Iyengar R (2000) Signaling networks: the origins of cellular multitasking. Cell 103:193-200.
-
(2000)
Cell
, vol.103
, pp. 193-200
-
-
Jordan, J.D.1
Landau, E.M.2
Iyengar, R.3
-
4
-
-
0025276049
-
Intracellular signalling as a parallel distributed process
-
Bray D (1990) Intracellular signalling as a parallel distributed process. J Theor Biol 143:215-231.
-
(1990)
J Theor Biol
, vol.143
, pp. 215-231
-
-
Bray, D.1
-
5
-
-
0029037739
-
Protein molecules as computational elements in living cells
-
Bray D (1995) Protein molecules as computational elements in living cells. Nature 376:307-312.
-
(1995)
Nature
, vol.376
, pp. 307-312
-
-
Bray, D.1
-
6
-
-
0029796238
-
Signal transduction: Specificity of growth factors explained by parallel distributed processing
-
Schamel WW, Dick TP (1996) Signal transduction: Specificity of growth factors explained by parallel distributed processing. Med Hypotheses 47:249-255.
-
(1996)
Med Hypotheses
, vol.47
, pp. 249-255
-
-
Schamel, W.W.1
Dick, T.P.2
-
7
-
-
0033555859
-
Emergent properties of networks of biological signaling pathways
-
Bhalla US, Iyengar R (1999) Emergent properties of networks of biological signaling pathways. Science 283:381-387.
-
(1999)
Science
, vol.283
, pp. 381-387
-
-
Bhalla, U.S.1
Iyengar, R.2
-
8
-
-
33846864345
-
-
eds Koonin EV, Wolf YI, Karev GP Springer, New York, pp
-
Fernandez P, Sole RV (2005) in Power Laws. Scale-Free Networks and Genome Biology, eds Koonin EV, Wolf YI, Karev GP (Springer, New York), pp 206-224.
-
(2005)
Power Laws. Scale-Free Networks and Genome Biology
, pp. 206-224
-
-
Fernandez, P.1
Sole, R.V.2
-
9
-
-
0027940353
-
Physics, computation, and why biology looks so different
-
Hopfield JJ (1994) Physics, computation, and why biology looks so different. J Theor Biol 171:53-60.
-
(1994)
J Theor Biol
, vol.171
, pp. 53-60
-
-
Hopfield, J.J.1
-
11
-
-
0036500993
-
Systems biology: A brief overview
-
Kitano H (2002) Systems biology: A brief overview. Science 295:1662-1664.
-
(2002)
Science
, vol.295
, pp. 1662-1664
-
-
Kitano, H.1
-
12
-
-
0346876288
-
Analysis and modelling of signal transduction pathways in systems biology
-
Cho K, Wolkenhauer O (2003) Analysis and modelling of signal transduction pathways in systems biology. Biochem Soc Trans 31:1503-1509.
-
(2003)
Biochem Soc Trans
, vol.31
, pp. 1503-1509
-
-
Cho, K.1
Wolkenhauer, O.2
-
13
-
-
10044298236
-
Reductionism and complexity in molecular biology. Scientists now have the tools to unravel biological and overcome the limitations of reductionism
-
Van Regenmortel MHV (2004) Reductionism and complexity in molecular biology. Scientists now have the tools to unravel biological and overcome the limitations of reductionism. EMBO Rep 5:1016-1020.
-
(2004)
EMBO Rep
, vol.5
, pp. 1016-1020
-
-
Van Regenmortel, M.H.V.1
-
14
-
-
27944493925
-
Scale-free networks in cell biology
-
Albert R (2005) Scale-free networks in cell biology. J Cell Sci 118:4947-4957.
-
(2005)
J Cell Sci
, vol.118
, pp. 4947-4957
-
-
Albert, R.1
-
15
-
-
0347004632
-
The next step in systems biology: Simulating the temporospatial dynamics of molecular network
-
Zhu H, Huang S, Dhar P (2003) The next step in systems biology: Simulating the temporospatial dynamics of molecular network. BioEssays 26:68-72.
-
(2003)
BioEssays
, vol.26
, pp. 68-72
-
-
Zhu, H.1
Huang, S.2
Dhar, P.3
-
16
-
-
32044474451
-
A hybrid approach for efficient and robust parameter estimation in biochemical pathways
-
Rodriguez-Fernandez M, Mendes P, Banga JR (2006) A hybrid approach for efficient and robust parameter estimation in biochemical pathways. Biosystems 83:248-265.
-
(2006)
Biosystems
, vol.83
, pp. 248-265
-
-
Rodriguez-Fernandez, M.1
Mendes, P.2
Banga, J.R.3
-
17
-
-
33749340654
-
Parameter estimation in biochemical systems models with alternating regression
-
Chou I, Martens H, Voit EO (2006) Parameter estimation in biochemical systems models with alternating regression. Theor Biol Med Model 3:25.
-
(2006)
Theor Biol Med Model
, vol.3
, pp. 25
-
-
Chou, I.1
Martens, H.2
Voit, E.O.3
-
18
-
-
33747876155
-
A decompositional approach to parameter estimation in pathway modeling: A case study of the Akt and MAPK pathways and their crosstalk
-
Koh G, Teong HFC, Clément M, Hsu D, Thiagarajan PS (2006) A decompositional approach to parameter estimation in pathway modeling: A case study of the Akt and MAPK pathways and their crosstalk. Bioinformatics 22:e271-80.
-
(2006)
Bioinformatics
, vol.22
-
-
Koh, G.1
Teong, H.F.C.2
Clément, M.3
Hsu, D.4
Thiagarajan, P.S.5
-
19
-
-
0034850921
-
Genomics, complexity and drug discovery: Insights from Boolean network models of cellular regulation
-
Huang S (2001) Genomics, complexity and drug discovery: Insights from Boolean network models of cellular regulation. Pharmacogenomics 2:203-222.
-
(2001)
Pharmacogenomics
, vol.2
, pp. 203-222
-
-
Huang, S.1
-
20
-
-
0345983657
-
From Boolean to probabilistic Boolean networks as models of genetic regulatory networks
-
Shmulevich I, Dougherty ER, Zhang W (2002) From Boolean to probabilistic Boolean networks as models of genetic regulatory networks. Proc IEEE 90:1778-1792.
-
(2002)
Proc IEEE
, vol.90
, pp. 1778-1792
-
-
Shmulevich, I.1
Dougherty, E.R.2
Zhang, W.3
-
21
-
-
0004161153
-
-
Oxford Univ Press, New York, pp
-
Kauffman SA (1993) in The Origins of Order (Oxford Univ Press, New York), pp 188-235.
-
(1993)
The Origins of Order
, pp. 188-235
-
-
Kauffman, S.A.1
-
22
-
-
0042808605
-
A natural class of robust networks
-
Aldana M, Cluzel P (2003) A natural class of robust networks. Proc Natl Acad Sci USA 100:8710-8714.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8710-8714
-
-
Aldana, M.1
Cluzel, P.2
-
23
-
-
0004161153
-
-
Oxford Univ Press, New York, pp
-
Kauffman SA (1993) in The Origins of Order (Oxford Univ Press, New York), pp 441-481.
-
(1993)
The Origins of Order
, pp. 441-481
-
-
Kauffman, S.A.1
-
24
-
-
27844553839
-
AKT crystal structure and AKT-specific inhibitors
-
Kumar CC, Madison V (2005) AKT crystal structure and AKT-specific inhibitors. Oncogene 24:7493-7501.
-
(2005)
Oncogene
, vol.24
, pp. 7493-7501
-
-
Kumar, C.C.1
Madison, V.2
-
25
-
-
27844601539
-
Regulation of the Akt kinase by interacting proteins
-
Du K, Tsichlis PN (2005) Regulation of the Akt kinase by interacting proteins. Oncogene 24:7401-7409.
-
(2005)
Oncogene
, vol.24
, pp. 7401-7409
-
-
Du, K.1
Tsichlis, P.N.2
-
26
-
-
0037067728
-
Inhibition of Src family kinases blocks epidermal growth factor (EGF)-induced activation of Akt, phosphorylation of c-Cbl, and ubiquitination of the EGF receptor
-
Kassenbrock CK, Hunter S, Garl P, Johnson GL, Anderson SM (2002) Inhibition of Src family kinases blocks epidermal growth factor (EGF)-induced activation of Akt, phosphorylation of c-Cbl, and ubiquitination of the EGF receptor. J Biol Chem 277:24967-24975.
-
(2002)
J Biol Chem
, vol.277
, pp. 24967-24975
-
-
Kassenbrock, C.K.1
Hunter, S.2
Garl, P.3
Johnson, G.L.4
Anderson, S.M.5
-
27
-
-
18944400789
-
Raf-1 serine 338 phosphorylation plays a key role in adhesion-dependent activation of extracellular signal-regulated kinase by epidermal growth factor
-
Edin ML, Juliano RL (2005) Raf-1 serine 338 phosphorylation plays a key role in adhesion-dependent activation of extracellular signal-regulated kinase by epidermal growth factor. Mol Cell Biol 25:4466-4475.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 4466-4475
-
-
Edin, M.L.1
Juliano, R.L.2
-
28
-
-
0031844821
-
Activation of Rac and Cdc42 by integrins mediates cell spreading
-
Price LS, Leng J, Schwartz MA, Bokoch GM (1998) Activation of Rac and Cdc42 by integrins mediates cell spreading. Mol Biol Cell 9:1863-1871.
-
(1998)
Mol Biol Cell
, vol.9
, pp. 1863-1871
-
-
Price, L.S.1
Leng, J.2
Schwartz, M.A.3
Bokoch, G.M.4
-
29
-
-
2542430932
-
-
eds Berrar DP, Dubitzky W, Granzow M Kluwer, Boston, pp
-
Wall ME, Rechtsteiner A, Rocha LM (2003) in A practical approach to microarray data analysis, eds Berrar DP, Dubitzky W, Granzow M (Kluwer, Boston), pp 91-109.
-
(2003)
A practical approach to microarray data analysis
, pp. 91-109
-
-
Wall, M.E.1
Rechtsteiner, A.2
Rocha, L.M.3
-
30
-
-
0003413187
-
-
Prentice-Hall, Englewood Cliffs, NJ, pp
-
Haykin S (1999) in Neural Networks, A Comprehensive Foundation (Prentice-Hall, Englewood Cliffs, NJ), pp 66-67.
-
(1999)
Neural Networks, A Comprehensive Foundation
, pp. 66-67
-
-
Haykin, S.1
-
31
-
-
0141596113
-
Molecular networks: The top-down view
-
Bray D (2003) Molecular networks: The top-down view. Science 301:1864-1865.
-
(2003)
Science
, vol.301
, pp. 1864-1865
-
-
Bray, D.1
-
32
-
-
23644437498
-
Formation of regulatory patterns during signal propagation in a mammalian cellular network
-
Ma'ayan A, et al. (2005) Formation of regulatory patterns during signal propagation in a mammalian cellular network. Science 309:1078-1083.
-
(2005)
Science
, vol.309
, pp. 1078-1083
-
-
Ma'ayan, A.1
-
34
-
-
2942530310
-
ERK and p38 MAPK-activated protein kinases: A family of protein kinases with diverse biological functions
-
Roux PP, Blenis J (2004) ERK and p38 MAPK-activated protein kinases: A family of protein kinases with diverse biological functions. Microbiol Mol Biol Rev 68:320-344.
-
(2004)
Microbiol Mol Biol Rev
, vol.68
, pp. 320-344
-
-
Roux, P.P.1
Blenis, J.2
-
35
-
-
1942421320
-
Calcium pumps of plasma membrane and cell interior
-
Strehler EE, Treiman M (2004) Calcium pumps of plasma membrane and cell interior. Curr Mol Med 4:323-335.
-
(2004)
Curr Mol Med
, vol.4
, pp. 323-335
-
-
Strehler, E.E.1
Treiman, M.2
-
36
-
-
0036117920
-
Integrins in invasive growth
-
Brakebusch C, Bouvard D, Stanchi F, Sakai T, Fässler R (2002) Integrins in invasive growth. J Clin Invest 109:999-1006.
-
(2002)
J Clin Invest
, vol.109
, pp. 999-1006
-
-
Brakebusch, C.1
Bouvard, D.2
Stanchi, F.3
Sakai, T.4
Fässler, R.5
-
37
-
-
0035478746
-
Protein-protein interactions at G-protein-coupled receptors
-
Milligan G, White JH (2001) Protein-protein interactions at G-protein-coupled receptors. Trends Pharmacol Sci 22:513-518.
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 513-518
-
-
Milligan, G.1
White, J.H.2
-
38
-
-
0032033682
-
G protein-coupled-receptor cross-talk: The fine-tuning of multiple receptor-signalling pathways
-
Selbie LA, Hill SJ (1998) G protein-coupled-receptor cross-talk: the fine-tuning of multiple receptor-signalling pathways. Trends Pharmacol Sci 19:87-93.
-
(1998)
Trends Pharmacol Sci
, vol.19
, pp. 87-93
-
-
Selbie, L.A.1
Hill, S.J.2
-
39
-
-
0034119581
-
Activation of MAPK cascades by G-protein-coupled receptors: The case of gonadotropin-releasing hormone receptor
-
Naor Z, Benard O, Seger R (2000) Activation of MAPK cascades by G-protein-coupled receptors: the case of gonadotropin-releasing hormone receptor. Trends Endocrinol Metab 11:91-99.
-
(2000)
Trends Endocrinol Metab
, vol.11
, pp. 91-99
-
-
Naor, Z.1
Benard, O.2
Seger, R.3
-
40
-
-
0035952656
-
Cell communication networks: Epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission
-
Gschwind A, Zwick E, Prenzel N, Leserer M, Ullrich A (2001) Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission. Oncogene 20:1594-1600.
-
(2001)
Oncogene
, vol.20
, pp. 1594-1600
-
-
Gschwind, A.1
Zwick, E.2
Prenzel, N.3
Leserer, M.4
Ullrich, A.5
-
41
-
-
18044387648
-
Raf kinase as a target for anticancer therapeutics
-
Sridhar SS, Hedley D, Siu LL (2005) Raf kinase as a target for anticancer therapeutics. Mol Cancer Ther 4:677-685.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 677-685
-
-
Sridhar, S.S.1
Hedley, D.2
Siu, L.L.3
|