Genomics, complexity and drug discovery: Insights from Boolean network models of cellular regulation

Pharmacogenomics

Volumn 2, Issue 3, 2001, Pages 203-222

  Huang, S ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Attractor; Boolean network; Cell fate; Differentiation; Microarray; Signal transduction

Indexed keywords

BETA GALACTOSIDASE; CELL PROTEIN; CISPLATIN; CYCLIC AMP; CYCLIN DEPENDENT KINASE; DNA; DRUG; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; RNA POLYMERASE; SALICYLIC ACID; SIMVASTATIN;

APOPTOSIS; CELL ACTIVITY; CELL DIFFERENTIATION; CELL FATE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG RESEARCH; DRUG TARGETING; GENE ACTIVITY; HUMAN; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; PHARMACOGENOMICS; PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; CELL DIFFERENTIATION; DRUG DESIGN; GENOME, HUMAN; HUMANS; MODELS, GENETIC; NEURAL NETWORKS (COMPUTER); SIGNAL TRANSDUCTION;

EID: 0034850921     PISSN: 14622416     EISSN: None     Source Type: Journal    
DOI: 10.1517/14622416.2.3.203     Document Type: Review

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