Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development

Genes and Development

Volumn 22, Issue 6, 2008, Pages 722-727

  Zhao, Haotian ^a   Ayrault, Olivier ^a   Zindy, Frederique ^a   Kim, Jee Hae ^b   Roussel, Martine F ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Atoh1 Math1; Bone morphogenic protein; Medulloblastoma; Mycn; Sonic hedgehog

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; NUCLEAR PROTEIN; PROTEASOME; PROTEIN MYCN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ATOH1; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR MATH1; UNCLASSIFIED DRUG;

ARTICLE; BRAIN DEVELOPMENT; BRAIN NERVE CELL; CANCER GROWTH; CELL CYCLE ARREST; CELL DIFFERENTIATION; CELL PROLIFERATION; CEREBELLUM CORTEX; DOWN REGULATION; DRUG INHIBITION; GENE CONTROL; GENE REPRESSION; GENETIC TRANSCRIPTION; IN VITRO STUDY; IN VIVO STUDY; MEDULLOBLASTOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; STEM CELL;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BLOTTING, WESTERN; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CEREBELLAR NEOPLASMS; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; IMMUNOENZYME TECHNIQUES; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MEDULLOBLASTOMA; MICE; NEURONS; NUCLEAR PROTEINS; ONCOGENE PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER;

ERINACEIDAE;

EID: 41149130332     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1636408     Document Type: Article

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