Development of an MFG-based retroviral vector system for secretion of high levels of functionally active human BMP4

Molecular Therapy

Volumn 4, Issue 2, 2001, Pages 95-104

  Peng, Hairong ^a   Chen, Shin Tai ^a   Wergedal, Jon E ^a   Polo, John M ^b   Yee, Jiing Kuan ^c   Lau, K H William ^a   Baylink, David J ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

^c CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

Bone formation; Bone morphogenetic protein 4; Hybrid vector; Marrow stromal cells; Retroviral vector (MFG)

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; HEMAGGLUTININ; HYBRID PROTEIN; STOMATITIS VESCULAR VIRUS G PROTEIN; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS VECTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BONE MARROW CELL; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CULTURE MEDIUM; FIBROBLAST; GENE CONSTRUCT; GENE DELETION; GENE EXPRESSION; GENETIC TRANSDUCTION; HUMAN; IMMUNOCOMPETENCE; MALE; NONHUMAN; OSSIFICATION; PROTEIN SECRETION; RAT; RETROVIRUS; STROMA CELL;

EID: 0034887774     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2001.0423     Document Type: Article

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