메뉴 건너뛰기




Volumn 82, Issue 7, 2008, Pages 3612-3623

Cdc55p-mediated E4orf4 growth inhibition in Saccharomyces cerevisiae is mediated only in part via the catalytic subunit of protein phosphatase 2A

Author keywords

[No Author keywords available]

Indexed keywords

EARLY REGION 4 OPEN READING FRAME PROTEIN; HOLOENZYME; PHOSPHOPROTEIN PHOSPHATASE 2A; PHOSPHOPROTEIN PHOSPHATASE CDC55P; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; PROTEIN P53; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 41149122572     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02435-07     Document Type: Article
Times cited : (12)

References (60)
  • 2
    • 0035049981 scopus 로고    scopus 로고
    • Selection of apoptosis-deficient adenovirus E4orf4 mutants in Saccharomyces cerevisiae
    • Afifi, R., R. Sharf, R. Shtrichman, and T. Kleinberger. 2001. Selection of apoptosis-deficient adenovirus E4orf4 mutants in Saccharomyces cerevisiae. J. Virol. 75:4444-4447.
    • (2001) J. Virol , vol.75 , pp. 4444-4447
    • Afifi, R.1    Sharf, R.2    Shtrichman, R.3    Kleinberger, T.4
  • 3
    • 0037031930 scopus 로고    scopus 로고
    • Angeles de la Torre-Ruiz, M., J. Torres, J. Arino, and E. Herrero. 2002. Sit4 is required for proper modulation of the biological functions mediated by Pkc1 and the cell integrity pathway in Saccharomyces cerevisiae. J. Biol. Chem. 277:33468-33476.
    • Angeles de la Torre-Ruiz, M., J. Torres, J. Arino, and E. Herrero. 2002. Sit4 is required for proper modulation of the biological functions mediated by Pkc1 and the cell integrity pathway in Saccharomyces cerevisiae. J. Biol. Chem. 277:33468-33476.
  • 4
    • 0030475875 scopus 로고    scopus 로고
    • The novel human protein serine/threonine phosphatase 6 is a functional homologue of budding yeast Sit4p and fission yeast ppe1, which are involved in cell cycle regulation
    • Bastians, H., and H. Ponstingl. 1996. The novel human protein serine/threonine phosphatase 6 is a functional homologue of budding yeast Sit4p and fission yeast ppe1, which are involved in cell cycle regulation. J. Cell Sci. 109:2865-2874.
    • (1996) J. Cell Sci , vol.109 , pp. 2865-2874
    • Bastians, H.1    Ponstingl, H.2
  • 6
    • 0029940998 scopus 로고    scopus 로고
    • Adenovirus E4 open reading frame 4 protein autoregulates E4 transcription by inhibiting E1A transactivation of the E4 promoter
    • Bondesson, M., K. Ohman, M. Manervik, S. Fan, and G. Akusjarvi. 1996. Adenovirus E4 open reading frame 4 protein autoregulates E4 transcription by inhibiting E1A transactivation of the E4 promoter. J. Virol. 70:3844-3851.
    • (1996) J. Virol , vol.70 , pp. 3844-3851
    • Bondesson, M.1    Ohman, K.2    Manervik, M.3    Fan, S.4    Akusjarvi, G.5
  • 7
    • 0026599048 scopus 로고
    • One-step transformation of yeast in stationary phase
    • Chen, D. C., B. C. Yang, and T. T. Kuo. 1992. One-step transformation of yeast in stationary phase. Curr. Genet. 21:83-84.
    • (1992) Curr. Genet , vol.21 , pp. 83-84
    • Chen, D.C.1    Yang, B.C.2    Kuo, T.T.3
  • 10
    • 0033738776 scopus 로고    scopus 로고
    • Mutation of the C-terminal leucine residue of PP2Ac inhibits PR55/B subunit binding and confers supersensitivity to microtubule destabilization in Saccharomyces cerevisiae
    • Evans, D. R., and B. A. Hemmings. 2000. Mutation of the C-terminal leucine residue of PP2Ac inhibits PR55/B subunit binding and confers supersensitivity to microtubule destabilization in Saccharomyces cerevisiae. Mol. Gen. Genet. 264:425-432.
    • (2000) Mol. Gen. Genet , vol.264 , pp. 425-432
    • Evans, D.R.1    Hemmings, B.A.2
  • 11
    • 0031014433 scopus 로고    scopus 로고
    • Mutations in the Saccharomyces cerevisiae type 2a protein phosphatase catalytic subunit reveal roles in cell wall integrity, actin cytoskeleton organization and mitosis
    • Evans, D. R., and M. J. Stark. 1997. Mutations in the Saccharomyces cerevisiae type 2a protein phosphatase catalytic subunit reveal roles in cell wall integrity, actin cytoskeleton organization and mitosis. Genetics 145:227-241.
    • (1997) Genetics , vol.145 , pp. 227-241
    • Evans, D.R.1    Stark, M.J.2
  • 12
    • 0035458366 scopus 로고    scopus 로고
    • The art and design of genetic screens: Yeast
    • Forsburg, S. L. 2001. The art and design of genetic screens: yeast. Nat. Rev. Genet. 2:659-668.
    • (2001) Nat. Rev. Genet , vol.2 , pp. 659-668
    • Forsburg, S.L.1
  • 14
    • 0037050026 scopus 로고    scopus 로고
    • Gavin, A. C., M. Bosche, R. Krause, P. Grandi, M. Marzioch, A. Bauer, J. Schultz, J. M. Rick, A. M. Michon, C. M. Cruciat, M. Remor, C. Hofert, M. Schelder, M. Brajenovic, H. Ruffner, A. Merino, K. Klein, M. Hudak, D. Dickson, T. Rudi, V. Gnau, A. Bauch, S. Bastuck, B. Huhse, C. Leutwein, M. A. Heurtier, R. R. Copley, A. Edelmann, E. Querfurth, V. Rybin, G. Drewes, M. Raida, T. Bouwmeester, P. Bork, B. Seraphin, B. Kuster, G. Neubauer, and G. Superti-Furga. 2002. Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature 415:141-147.
    • Gavin, A. C., M. Bosche, R. Krause, P. Grandi, M. Marzioch, A. Bauer, J. Schultz, J. M. Rick, A. M. Michon, C. M. Cruciat, M. Remor, C. Hofert, M. Schelder, M. Brajenovic, H. Ruffner, A. Merino, K. Klein, M. Hudak, D. Dickson, T. Rudi, V. Gnau, A. Bauch, S. Bastuck, B. Huhse, C. Leutwein, M. A. Heurtier, R. R. Copley, A. Edelmann, E. Querfurth, V. Rybin, G. Drewes, M. Raida, T. Bouwmeester, P. Bork, B. Seraphin, B. Kuster, G. Neubauer, and G. Superti-Furga. 2002. Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature 415:141-147.
  • 15
    • 34447276926 scopus 로고    scopus 로고
    • An in vivo assay to quantify stable protein phosphatase 2A (PP2A) heterotrimeric species
    • Gentry, M. S., R. L. Hallberg, and D. C. Pallas. 2006. An in vivo assay to quantify stable protein phosphatase 2A (PP2A) heterotrimeric species. Methods Mol. Biol. 365:71-84.
    • (2006) Methods Mol. Biol , vol.365 , pp. 71-84
    • Gentry, M.S.1    Hallberg, R.L.2    Pallas, D.C.3
  • 16
    • 20444485337 scopus 로고    scopus 로고
    • A novel assay for protein phosphatase 2A (PP2A) complexes in vivo reveals differential effects of covalent modifications on different Saccharomyces cerevisiae PP2A heterotrimers
    • Gentry, M. S., Y. Li, H. Wei, F. F. Syed, S. H. Patel, R. L. Hallberg, and D. C. Pallas. 2005. A novel assay for protein phosphatase 2A (PP2A) complexes in vivo reveals differential effects of covalent modifications on different Saccharomyces cerevisiae PP2A heterotrimers. Eukaryot. Cell 4:1029-1040.
    • (2005) Eukaryot. Cell , vol.4 , pp. 1029-1040
    • Gentry, M.S.1    Li, Y.2    Wei, H.3    Syed, F.F.4    Patel, S.H.5    Hallberg, R.L.6    Pallas, D.C.7
  • 17
    • 0032873415 scopus 로고    scopus 로고
    • Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae
    • Goldstein, A. L., and J. H. McCusker. 1999. Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae. Yeast 15:1541-1553.
    • (1999) Yeast , vol.15 , pp. 1541-1553
    • Goldstein, A.L.1    McCusker, J.H.2
  • 18
    • 0026091769 scopus 로고
    • CDC55, a Saccharomyces cerevisiae gene involved in cellular morphogenesis: Identification, characterization, and homology to the B subunit of mammalian type 2A protein phosphatase
    • Healy, A. M., S. Zolnierowicz, A. E. Stapleton, M. Goebl, A. A. DePaoli-Roach, and J. R. Pringle. 1991. CDC55, a Saccharomyces cerevisiae gene involved in cellular morphogenesis: identification, characterization, and homology to the B subunit of mammalian type 2A protein phosphatase. Mol. Cell. Biol. 11:5767-5780.
    • (1991) Mol. Cell. Biol , vol.11 , pp. 5767-5780
    • Healy, A.M.1    Zolnierowicz, S.2    Stapleton, A.E.3    Goebl, M.4    DePaoli-Roach, A.A.5    Pringle, J.R.6
  • 19
    • 0036032778 scopus 로고    scopus 로고
    • Regulators of serine/threonine protein phosphatases at the dawn of a clinical era?
    • Honkanen, R. E., and T. Golden. 2002. Regulators of serine/threonine protein phosphatases at the dawn of a clinical era? Curr. Med. Chem. 9:2055-2075.
    • (2002) Curr. Med. Chem , vol.9 , pp. 2055-2075
    • Honkanen, R.E.1    Golden, T.2
  • 20
    • 0001778394 scopus 로고
    • Phosphatases: New respect for cellular second banana
    • Hopkin, K. 1995. Phosphatases: new respect for cellular second banana. J. NIH Res. 7:27-30.
    • (1995) J. NIH Res , vol.7 , pp. 27-30
    • Hopkin, K.1
  • 21
    • 0035252894 scopus 로고    scopus 로고
    • Protein phosphatase 2A: A highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
    • Janssens, V., and J. Goris. 2001. Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling. Biochem. J. 353:417-439.
    • (2001) Biochem. J , vol.353 , pp. 417-439
    • Janssens, V.1    Goris, J.2
  • 22
    • 0032516168 scopus 로고    scopus 로고
    • Regulation of adenovirus alternative RNA splicing by dephosphorylation of SR proteins
    • Kanopka, A., O. Muhlemann, S. Petersen-Mahrt, C. Estmer, C. Ohrmalm, and G. Akusjarvi. 1998. Regulation of adenovirus alternative RNA splicing by dephosphorylation of SR proteins. Nature 393:185-187.
    • (1998) Nature , vol.393 , pp. 185-187
    • Kanopka, A.1    Muhlemann, O.2    Petersen-Mahrt, S.3    Estmer, C.4    Ohrmalm, C.5    Akusjarvi, G.6
  • 23
    • 0028073155 scopus 로고
    • Control of cellular morphogenesis by the Ip12/Bem2 GTPase-activating protein: Possible role of protein phosphorylation
    • Kim, Y. J., L. Francisco, G. C. Chen, E. Marcotte, and C. S. Chan. 1994. Control of cellular morphogenesis by the Ip12/Bem2 GTPase-activating protein: possible role of protein phosphorylation. J. Cell Biol. 127:1381-1394.
    • (1994) J. Cell Biol , vol.127 , pp. 1381-1394
    • Kim, Y.J.1    Francisco, L.2    Chen, G.C.3    Marcotte, E.4    Chan, C.S.5
  • 24
    • 0027360098 scopus 로고
    • Adenovirus E4orf4 protein binds to protein phosphatase 2A, and the complex down regulates E1A-enhanced junB transcription
    • Kleinberger, T., and T. Shenk. 1993. Adenovirus E4orf4 protein binds to protein phosphatase 2A, and the complex down regulates E1A-enhanced junB transcription. J. Virol. 67:7556-7560.
    • (1993) J. Virol , vol.67 , pp. 7556-7560
    • Kleinberger, T.1    Shenk, T.2
  • 25
    • 0035939670 scopus 로고    scopus 로고
    • Adenovirus E4orf4 protein induces PP2A-dependent growth arrest in Saccharomyces cerevisiae and interacts with the anaphase-promoting complex/cyclosome
    • Kornitzer, D., R. Sharf, and T. Kleinberger. 2001. Adenovirus E4orf4 protein induces PP2A-dependent growth arrest in Saccharomyces cerevisiae and interacts with the anaphase-promoting complex/cyclosome. J. Cell Biol. 154: 331-344.
    • (2001) J. Cell Biol , vol.154 , pp. 331-344
    • Kornitzer, D.1    Sharf, R.2    Kleinberger, T.3
  • 26
    • 0036096778 scopus 로고    scopus 로고
    • B56-associated protein phosphatase 2A is required for survival and protects from apoptosis in Drosophila melanogaster
    • Li, X., A. Scuderi, A. Letsou, and D. M. Virshup. 2002. B56-associated protein phosphatase 2A is required for survival and protects from apoptosis in Drosophila melanogaster. Mol. Cell. Biol. 22:3674-3684.
    • (2002) Mol. Cell. Biol , vol.22 , pp. 3674-3684
    • Li, X.1    Scuderi, A.2    Letsou, A.3    Virshup, D.M.4
  • 27
    • 0035163836 scopus 로고    scopus 로고
    • Caspase activation by adenovirus e4orf4 protein is cell line specific and is mediated by the death receptor pathway
    • Livne, A., R. Shtrichman, and T. Kleinberger. 2001. Caspase activation by adenovirus e4orf4 protein is cell line specific and is mediated by the death receptor pathway. J. Virol. 75:789-798.
    • (2001) J. Virol , vol.75 , pp. 789-798
    • Livne, A.1    Shtrichman, R.2    Kleinberger, T.3
  • 28
    • 0035914309 scopus 로고    scopus 로고
    • Interaction between protein phosphatase 5 and the A subunit of protein phosphatase 2A: Evidence for a heterotrimeric form of protein phosphatase 5
    • Lubert, E. J., Y. Hong, and K. D. Sarge. 2001. Interaction between protein phosphatase 5 and the A subunit of protein phosphatase 2A: evidence for a heterotrimeric form of protein phosphatase 5. J. Biol. Chem. 276:38582-38587.
    • (2001) J. Biol. Chem , vol.276 , pp. 38582-38587
    • Lubert, E.J.1    Hong, Y.2    Sarge, K.D.3
  • 29
    • 20444419344 scopus 로고    scopus 로고
    • Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
    • MacKeigan, J. P., L. O. Murphy, and J. Blenis. 2005. Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance. Nat. Cell Biol. 7:591-600.
    • (2005) Nat. Cell Biol , vol.7 , pp. 591-600
    • MacKeigan, J.P.1    Murphy, L.O.2    Blenis, J.3
  • 30
    • 0033541370 scopus 로고    scopus 로고
    • Adenovirus E4 open reading frame 4-induced dephosphorylation inhibits E1A activation of the E2 promoter and E2F-1-mediated transactivation independently of the retinoblastoma tumor suppressor protein
    • Mannervik, M., S. Fan, A. C. Strom, K. Helin, and G. Akusjarvi. 1999. Adenovirus E4 open reading frame 4-induced dephosphorylation inhibits E1A activation of the E2 promoter and E2F-1-mediated transactivation independently of the retinoblastoma tumor suppressor protein. Virology 256:313-321.
    • (1999) Virology , vol.256 , pp. 313-321
    • Mannervik, M.1    Fan, S.2    Strom, A.C.3    Helin, K.4    Akusjarvi, G.5
  • 31
    • 0033881446 scopus 로고    scopus 로고
    • Induction of p53-independent apoptosis by the adenovirus E4orf4 protein requires binding to the Bα subunit of protein phosphatase 2A
    • Marcellus, R. C., H. Chan, D. Paquette, S. Thirlwell, D. Boivin, and P. E. Branton. 2000. Induction of p53-independent apoptosis by the adenovirus E4orf4 protein requires binding to the Bα subunit of protein phosphatase 2A. J. Virol. 74:7869-7877.
    • (2000) J. Virol , vol.74 , pp. 7869-7877
    • Marcellus, R.C.1    Chan, H.2    Paquette, D.3    Thirlwell, S.4    Boivin, D.5    Branton, P.E.6
  • 32
    • 0031816872 scopus 로고    scopus 로고
    • The early region 4 orf4 protein of human adenovirus type 5 induces p53-independent cell death by apoptosis
    • Marcellus, R. C., J. N. Lavoie, D. Boivin, G. C. Shore, G. Ketner, and P. E. Branton. 1998. The early region 4 orf4 protein of human adenovirus type 5 induces p53-independent cell death by apoptosis. J. Virol. 72:7144-7153.
    • (1998) J. Virol , vol.72 , pp. 7144-7153
    • Marcellus, R.C.1    Lavoie, J.N.2    Boivin, D.3    Shore, G.C.4    Ketner, G.5    Branton, P.E.6
  • 33
    • 0030464317 scopus 로고    scopus 로고
    • Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast
    • Minshull, J., A. Straight, A. D. Rudner, A. F. Dernburg, A. Belmont, and A. W. Murray. 1996. Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast. Curr. Biol. 6:1609-1620.
    • (1996) Curr. Biol , vol.6 , pp. 1609-1620
    • Minshull, J.1    Straight, A.2    Rudner, A.D.3    Dernburg, A.F.4    Belmont, A.5    Murray, A.W.6
  • 35
    • 0022504637 scopus 로고
    • Genealogy of principal strains of the yeast genetic stock center
    • Mortimer, R. K., and J. R. Johnston. 1986. Genealogy of principal strains of the yeast genetic stock center. Genetics 113:35-43.
    • (1986) Genetics , vol.113 , pp. 35-43
    • Mortimer, R.K.1    Johnston, J.R.2
  • 36
    • 0026669557 scopus 로고
    • Adenovirus E4orf4 protein reduces phosphorylation of c-Fos and E1A proteins while simultaneously reducing the level of AP-1
    • Muller, U., T. Kleinberger, and T. Shenk. 1992. Adenovirus E4orf4 protein reduces phosphorylation of c-Fos and E1A proteins while simultaneously reducing the level of AP-1. J. Virol. 66:5867-5878.
    • (1992) J. Virol , vol.66 , pp. 5867-5878
    • Muller, U.1    Kleinberger, T.2    Shenk, T.3
  • 37
    • 0027143725 scopus 로고
    • Protein serine/threonine phosphatases: Structure, regulation, and functions in cell growth
    • Mumby, M. C., and G. Walter. 1993. Protein serine/threonine phosphatases: structure, regulation, and functions in cell growth. Physiol. Rev. 73:673-699.
    • (1993) Physiol. Rev , vol.73 , pp. 673-699
    • Mumby, M.C.1    Walter, G.2
  • 38
    • 0029915925 scopus 로고    scopus 로고
    • 1 arrest of Saccharomyces cerevisiae
    • 1 arrest of Saccharomyces cerevisiae. Genes Dev. 10:382-394.
    • (1996) Genes Dev , vol.10 , pp. 382-394
    • Nickels, J.T.1    Broach, J.R.2
  • 40
    • 0025936172 scopus 로고
    • Protein phosphatase 2A in Saccharomyces cerevisiae: Effects on cell growth and bud morphogenesis
    • Ronne, H., M. Carlberg, G. Z. Hu, and J. O. Nehlin. 1991. Protein phosphatase 2A in Saccharomyces cerevisiae: effects on cell growth and bud morphogenesis. Mol. Cell. Biol. 11:4876-4884.
    • (1991) Mol. Cell. Biol , vol.11 , pp. 4876-4884
    • Ronne, H.1    Carlberg, M.2    Hu, G.Z.3    Nehlin, J.O.4
  • 41
    • 0035974917 scopus 로고    scopus 로고
    • Toxicity of human adenovirus E4orf4 protein in Saccharomyces cerevisiae results from interactions with the Cdc55 regulatory B subunit of PP2A
    • Roopchand, D. E., J. M. Lee, S. Shahinian, D. Paquette, H. Bussey, and P. E. Branton. 2001. Toxicity of human adenovirus E4orf4 protein in Saccharomyces cerevisiae results from interactions with the Cdc55 regulatory B subunit of PP2A. Oncogene 20:5279-5290.
    • (2001) Oncogene , vol.20 , pp. 5279-5290
    • Roopchand, D.E.1    Lee, J.M.2    Shahinian, S.3    Paquette, D.4    Bussey, H.5    Branton, P.E.6
  • 42
    • 0031949940 scopus 로고    scopus 로고
    • Adenovirus type 5 E4 open reading frame 4 protein induces apoptosis in transformed cells
    • Shtrichman, R., and T. Kleinberger. 1998. Adenovirus type 5 E4 open reading frame 4 protein induces apoptosis in transformed cells. J. Virol. 72:2975-2982.
    • (1998) J. Virol , vol.72 , pp. 2975-2982
    • Shtrichman, R.1    Kleinberger, T.2
  • 43
    • 0033621057 scopus 로고    scopus 로고
    • Induction of apoptosis by adenovirus E4orf4 protein is specific to transformed cells and requires an interaction with protein phosphatase 2A
    • Shtrichman, R., R. Sharf, H. Barr, T. Dobner, and T. Kleinberger. 1999. Induction of apoptosis by adenovirus E4orf4 protein is specific to transformed cells and requires an interaction with protein phosphatase 2A. Proc. Natl. Acad. Sci. USA 96:10080-10085.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 10080-10085
    • Shtrichman, R.1    Sharf, R.2    Barr, H.3    Dobner, T.4    Kleinberger, T.5
  • 44
    • 0034601367 scopus 로고    scopus 로고
    • Adenovirus E4orf4 protein interacts with both Bα and B′ subunits of protein phosphatase 2A, but E4orf4-induced apoptosis is mediated only by the interaction with Bα
    • Shtrichman, R., R. Sharf, and T. Kleinberger. 2000. Adenovirus E4orf4 protein interacts with both Bα and B′ subunits of protein phosphatase 2A, but E4orf4-induced apoptosis is mediated only by the interaction with Bα. Oncogene 19:3757-3765.
    • (2000) Oncogene , vol.19 , pp. 3757-3765
    • Shtrichman, R.1    Sharf, R.2    Kleinberger, T.3
  • 45
    • 0030973160 scopus 로고    scopus 로고
    • Molecular genetic analysis of Rts1p, a B′ regulatory subunit of Saccharomyces cerevisiae protein phosphatase 2A
    • Shu, Y., H. Yang, E. Hallberg, and R. Hallberg. 1997. Molecular genetic analysis of Rts1p, a B′ regulatory subunit of Saccharomyces cerevisiae protein phosphatase 2A. Mol. Cell. Biol. 17:3242-3253.
    • (1997) Mol. Cell. Biol , vol.17 , pp. 3242-3253
    • Shu, Y.1    Yang, H.2    Hallberg, E.3    Hallberg, R.4
  • 46
    • 0024669291 scopus 로고
    • A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
    • Sikorski, R. S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27.
    • (1989) Genetics , vol.122 , pp. 19-27
    • Sikorski, R.S.1    Hieter, P.2
  • 47
    • 0037007096 scopus 로고    scopus 로고
    • Actions of PP2A on the MAP kinase pathway and apoptosis are mediated by distinct regulatory subunits
    • Silverstein, A. M., C. A. Barrow, A. J. Davis, and M. C. Mumby. 2002. Actions of PP2A on the MAP kinase pathway and apoptosis are mediated by distinct regulatory subunits. Proc. Natl. Acad. Sci. USA 99:4221-4226.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 4221-4226
    • Silverstein, A.M.1    Barrow, C.A.2    Davis, A.J.3    Mumby, M.C.4
  • 48
    • 9144223779 scopus 로고    scopus 로고
    • Critical role for protein phosphatase 2A heterotrimers in mammalian cell survival
    • Strack, S., J. T. Cribbs, and L. Gomez. 2004. Critical role for protein phosphatase 2A heterotrimers in mammalian cell survival. J. Biol. Chem. 279:47732-47739.
    • (2004) J. Biol. Chem , vol.279 , pp. 47732-47739
    • Strack, S.1    Cribbs, J.T.2    Gomez, L.3
  • 50
    • 0034331359 scopus 로고    scopus 로고
    • Carboxyl methylation regulates phosphoprotein phosphatase 2A by controlling the association of regulatory B subunits
    • Tolstykh, T., J. Lee, S. Vafai, and J. B. Stock. 2000. Carboxyl methylation regulates phosphoprotein phosphatase 2A by controlling the association of regulatory B subunits. EMBO J. 19:5682-5691.
    • (2000) EMBO J , vol.19 , pp. 5682-5691
    • Tolstykh, T.1    Lee, J.2    Vafai, S.3    Stock, J.B.4
  • 51
    • 10744230485 scopus 로고    scopus 로고
    • Tong, A. H., G. Lesage, G. D. Bader, H. Ding, H. Xu, X. Xin, J. Young, G. F. Berriz, R. L. Brost, M. Chang, Y. Chen, X. Cheng, G. Chua, H. Friesen, D. S. Goldberg, J. Haynes, C. Humphries, G. He, S. Hussein, L. Ke, N. Krogan, Z. Li, J. N. Levinson, H. Lu, P. Menard, C. Munyana, A. B. Parsons, O. Ryan, R. Tonikian, T. Roberts, A. M. Sdicu, J. Shapiro, B. Sheikh, B. Suter, S. L. Wong, L. V. Zhang, H. Zhu, C. G. Burd, S. Munro, C. Sander, J. Rine, J. Greenblatt, M. Peter, A. Bretscher, G. Bell, F. P. Roth, G. W. Brown, B. Andrews, H. Bussey, and C. Boone. 2004. Global mapping of the yeast genetic interaction network. Science 303:808-813.
    • Tong, A. H., G. Lesage, G. D. Bader, H. Ding, H. Xu, X. Xin, J. Young, G. F. Berriz, R. L. Brost, M. Chang, Y. Chen, X. Cheng, G. Chua, H. Friesen, D. S. Goldberg, J. Haynes, C. Humphries, G. He, S. Hussein, L. Ke, N. Krogan, Z. Li, J. N. Levinson, H. Lu, P. Menard, C. Munyana, A. B. Parsons, O. Ryan, R. Tonikian, T. Roberts, A. M. Sdicu, J. Shapiro, B. Sheikh, B. Suter, S. L. Wong, L. V. Zhang, H. Zhu, C. G. Burd, S. Munro, C. Sander, J. Rine, J. Greenblatt, M. Peter, A. Bretscher, G. Bell, F. P. Roth, G. W. Brown, B. Andrews, H. Bussey, and C. Boone. 2004. Global mapping of the yeast genetic interaction network. Science 303:808-813.
  • 52
    • 0037044801 scopus 로고    scopus 로고
    • Regulation of the cell integrity pathway by rapamycin-sensitive TOR function in budding yeast
    • Torres, J., C. J. Di Como, E. Herrero, and M. A. De La Torre-Ruiz. 2002. Regulation of the cell integrity pathway by rapamycin-sensitive TOR function in budding yeast. J. Biol. Chem. 277:43495-43504.
    • (2002) J. Biol. Chem , vol.277 , pp. 43495-43504
    • Torres, J.1    Di Como, C.J.2    Herrero, E.3    De La Torre-Ruiz, M.A.4
  • 54
    • 0026646041 scopus 로고
    • Inactivation of the protein phosphatase 2A regulatory subunit A results in morphological and transcriptional defects in Saccharomyces cerevisiae
    • van Zyl, W., W. Huang, A. A. Sneddon, M. Stark, S. Camier, M. Werner, C. Marck, A. Sentenac, and J. R. Broach. 1992. Inactivation of the protein phosphatase 2A regulatory subunit A results in morphological and transcriptional defects in Saccharomyces cerevisiae. Mol. Cell. Biol. 12:4946-4959.
    • (1992) Mol. Cell. Biol , vol.12 , pp. 4946-4959
    • van Zyl, W.1    Huang, W.2    Sneddon, A.A.3    Stark, M.4    Camier, S.5    Werner, M.6    Marck, C.7    Sentenac, A.8    Broach, J.R.9
  • 55
    • 0030693087 scopus 로고    scopus 로고
    • CDC20 and CDH1: A family of substrate-specific activators of APC-dependent proteolysis
    • Visintin, R., S. Prinz, and A. Amon. 1997. CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis. Science 278:460-463.
    • (1997) Science , vol.278 , pp. 460-463
    • Visintin, R.1    Prinz, S.2    Amon, A.3
  • 56
    • 0028676232 scopus 로고
    • New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae
    • Wach, A., A. Brachat, R. Pohlmann, and P. Philippsen. 1994. New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae. Yeast 10:1793-1808.
    • (1994) Yeast , vol.10 , pp. 1793-1808
    • Wach, A.1    Brachat, A.2    Pohlmann, R.3    Philippsen, P.4
  • 57
    • 0031046069 scopus 로고    scopus 로고
    • Cdc55p, the B-type regulatory subunit of protein phosphatase 2A, has multiple functions in mitosis and is required for the kinetochore/spindle checkpoint in Saccharomyces cerevisiae
    • Wang, Y., and D. J. Burke. 1997. Cdc55p, the B-type regulatory subunit of protein phosphatase 2A, has multiple functions in mitosis and is required for the kinetochore/spindle checkpoint in Saccharomyces cerevisiae. Mol. Cell. Biol. 17:620-626.
    • (1997) Mol. Cell. Biol , vol.17 , pp. 620-626
    • Wang, Y.1    Burke, D.J.2
  • 58
    • 0035846951 scopus 로고    scopus 로고
    • Carboxymethylation of the PP2A catalytic subunit in Saccharomyces cerevisiae is required for efficient interaction with the B-type subunits Cdc55p and Rts1p
    • Wei, H., D. G. Ashby, C. S. Moreno, E. Ogris, F. M. Yeong, A. H. Corbett, and D. C. Pallas. 2001. Carboxymethylation of the PP2A catalytic subunit in Saccharomyces cerevisiae is required for efficient interaction with the B-type subunits Cdc55p and Rts1p. J. Biol. Chem. 276:1570-1577.
    • (2001) J. Biol. Chem , vol.276 , pp. 1570-1577
    • Wei, H.1    Ashby, D.G.2    Moreno, C.S.3    Ogris, E.4    Yeong, F.M.5    Corbett, A.H.6    Pallas, D.C.7
  • 59
    • 0034331296 scopus 로고    scopus 로고
    • Carboxyl methylation of the phosphoprotein phosphatase 2A catalytic subunit promotes its functional association with regulatory subunits in vivo
    • Wu, J., T. Tolstykh, J. Lee, K. Boyd, J. B. Stock, and J. R. Broach. 2000. Carboxyl methylation of the phosphoprotein phosphatase 2A catalytic subunit promotes its functional association with regulatory subunits in vivo. EMBO J. 19:5672-5681.
    • (2000) EMBO J , vol.19 , pp. 5672-5681
    • Wu, J.1    Tolstykh, T.2    Lee, J.3    Boyd, K.4    Stock, J.B.5    Broach, J.R.6
  • 60
    • 0035177048 scopus 로고    scopus 로고
    • Methylation of the protein phosphatase 2A catalytic subunit is essential for association of Balpha regulatory subunit but not SG2NA, striatin, or polyomavirus middle tumor antigen
    • Yu, X. X., X. Du, C. S. Moreno, R. E. Green, E. Ogris, Q. Feng, L. Chou, M. J. McQuoid, and D. C. Pallas. 2001. Methylation of the protein phosphatase 2A catalytic subunit is essential for association of Balpha regulatory subunit but not SG2NA, striatin, or polyomavirus middle tumor antigen. Mol. Biol. Cell 12:185-199.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 185-199
    • Yu, X.X.1    Du, X.2    Moreno, C.S.3    Green, R.E.4    Ogris, E.5    Feng, Q.6    Chou, L.7    McQuoid, M.J.8    Pallas, D.C.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.