Effect of common anesthetics on dendritic properties in layer 5 neocortical pyramidal neurons

Journal of Neurophysiology

Volumn 99, Issue 3, 2008, Pages 1394-1407

  Potez, Sarah ^a   Larkum, Matthew E ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANESTHETIC AGENT; KETAMINE PLUS XYLAZINE; LIDOCAINE; PENTOBARBITAL; UNCLASSIFIED DRUG; URETHAN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; DRUG MECHANISM; IN VITRO STUDY; IN VIVO STUDY; NEOCORTEX; NERVE EXCITABILITY; NERVE POTENTIAL; NONHUMAN; PAIN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; WHOLE CELL;

ACTION POTENTIALS; ANALYSIS OF VARIANCE; ANESTHETICS; ANIMALS; ANIMALS, NEWBORN; CALCIUM; DENDRITES; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRIC STIMULATION; NEOCORTEX; PATCH-CLAMP TECHNIQUES; PYRAMIDAL CELLS; RATS; RATS, WISTAR;

EID: 40949163812     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.01126.2007     Document Type: Article

References (73)

1. Accorsi-Mendonca D, Leao RM, Aguiar JF, Varanda WA, Machado BH. Urethane inhibits the GABAergic neurotransmission in the nucleus of the solitary tract of rat brain stem slices. Am J Physiol Regul Integr Comp Physiol 292: R396-R402, 2007.
2. Adelsberger H, Garaschuk O, Konnerth A. Cortical calcium waves in resting newborn mice. Nat Neurosci 8: 988-990, 2005.
3. Antkowiak B. Different actions of general anesthetics on the firing patterns of neocortical neurons mediated by the GABA(A) receptor. Anesthesiology 91: 500-511, 1999.
4. Antkowiak B. In vitro networks: cortical mechanisms of anaesthetic action. Br J Anaesth 89: 102-111, 2002.
5. Arhem P, Klement G, Nilsson J. Mechanisms of anesthesia: towards integrating network, cellular, and molecular level modeling. Neuropsychopharmacology 28, Suppl. 1: S40-S47, 2003.
6. h disconnects somatic and dendritic spike initiation zones in layer V pyramidal neurons. J Neurophysiol 90: 2428-2437, 2003.
7. Cabral AD, Kapusta DR, Kenigs VA, Varner KJ. Central alpha2-receptor mechanisms contribute to enhanced renal responses during ketamine-xylazine anesthesia. Am J Physiol Regul Integr Comp Physiol 275: R1867-R1874, 1998.
8. Christophe E, Doerflinger N, Lavery DJ, Molnar Z, Charpak S, Audinat E. Two populations of layer V pyramidal cells of the mouse neocortex: development and sensitivity to anesthetics. J Neurophysiol 94: 3357-3367, 2005.
9. Dilger JP. The effects of general anaesthetics on ligand-gated ion channels. Br J Anaesth 89: 41-51, 2002.
10. Drafts BC, Fisher JL. Identification of structures within GABAA receptor alpha subunits that regulate the agonist action of pentobarbital. J Pharmacol Exp Ther 318: 1094-1101, 2006.
11. Farrant M, Nusser Z. Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors. Nat Rev Neurosci 6: 215-229, 2005.
12. - current. J Neurosci 13: 3211-3221, 1993.
13. Field KJ, Lang CM. Hazards of urethane (ethyl carbamate): a review of the literature. Lab Anim 22: 255-262, 1988.
14. Franks NP. Molecular targets underlying general anaesthesia. Br J Pharmacol 147, Suppl. 1: S72-S81, 2006.
15. Franks NP, Lieb WR. Molecular and cellular mechanisms of general anaesthesia. Nature 367: 607-614, 1994.
16. Friederich P, Benzenberg D, Urban BW. Ketamine and propofol differentially inhibit human neuronal K(+-) channels. Eur J Anaesthesiol 18: 177-183, 2001.
17. Gage PW, Robertson B. Prolongation of inhibitory postsynaptic currents by pentobarbitone, halothane and ketamine in CA1 pyramidal cells in rat hippocampus. Br J Pharmacol 85: 675-681, 1985.
18. Garrett KM, Gan J. Enhancement of gamma-aminobutyric acid A receptor activity by alpha-chloralose. J Pharmacol Exp Ther 285: 680-686, 1998.
19. Green CJ, Knight J, Precious S, Simpkin S. Ketamine alone and combined with diazepam or xylazine in laboratory animals: a 10 year experience. Lab Anim 15: 163-170, 1981.
20. Hara K, Harris RA. The anesthetic mechanism of urethane: the effects on neurotransmitter-gated ion channels. Anesth Analg 94: 313-318, 2002.
21. Hara Y, Chugun A, Nakaya H, Kondo H. Tonic block of the sodium and calcium currents by ketamine in isolated guinea pig ventricular myocytes. J Vet Med Sci 60: 479-483, 1998.
22. Hatakeyama N, Yamazaki M, Shibuya N, Yamamura S, Momose Y. Effects of ketamine on voltage-dependent calcium currents and membrane potentials in single bullfrog atrial cells. J Anesth 15: 149-153, 2001.
23. Helmchen F, Svoboda K, Denk W, Tank DW. In vivo dendritic calcium dynamics in deep-layer cortical pyramidal neurons. Nat Neurosci 2: 989-996, 1999.
24. Hirota K, Lambert DG. Ketamine: its mechanism(s) of action and unusual clinical uses. Br J Anaesth 77: 441-444, 1996.
25. Hirsch JA, Alonso JM, Reid RC. Visually evoked calcium action-potentials in cat striate cortex. Nature 378: 612-616, 1995.
26. Iansek R, Redman SJ. The amplitude, time course and charge of unitary excitatory post-synaptic potentials evoked in spinal motoneurone dendrites. J Physiol 234: 665-688, 1973.
27. Irifune M, Sato T, Kamata Y, Nishikawa T, Dohi T, Kawahara M. Evidence for GABA(A) receptor agonistic properties of ketamine: convulsive and anesthetic behavioral models in mice. Anesth Analg 91: 230-236, 2000.
28. Kapur S, Seeman P. NMDA receptor antagonists ketamine and PCP have direct effects on the dopamine D(2) and serotonin 5-HT(2) receptors: implications for models of schizophrenia. Mol Psychiatry 7: 837-844, 2002.
29. Kim HG, Connors BW. Apical dendrites of the neocortex: correlation between sodium- and calcium-dependent spiking and pyramidal cell morphology. J Neurosci 13: 5301-5311, 1993.
30. Kitayama M, Hirota K, Kudo M, Kudo T, Ishihara H, Matsuki A. Inhibitory effects of intravenous anaesthetic agents on K(+-)-evoked glutamate release from rat cerebrocortical slices. Involvement of voltage-sensitive Ca(2-+) channels and GABA(A) receptors. Naunyn Schmiedebergs Arch Pharmacol 366: 246-253, 2002.
31. 2-+ channels. Biol Reprod 43: 614-618, 1990.
32. Krystal JH, Karper LP, Seibyl JP, Freeman GK, Delaney R, Bremner JD, Heninger GR, Bowers MB Jr, Charney DS. Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch Gen Psychiatry 51: 199-214, 1994.
33. Larkum ME, Kaiser KM, Sakmann B. Calcium electrogenesis in distal apical dendrites of layer 5 pyramidal cells at a critical frequency of back-propagating action potentials. Proc Natl Acad Sci USA 96: 14600-14604, 1999a.
34. -+ action potentials in distal and terminal dendrites of rat neocortical pyramidal neurons in vitro and in vivo. J Neurosci 22: 6991-7005, 2002.
35. Larkum ME, Zhu JJ, Sakmann B. A new cellular mechanism for coupling inputs arriving at different cortical layers. Nature 398: 338-341, 1999b.
36. Larkum ME, Zhu JJ, Sakmann B. Dendritic mechanisms underlying the coupling of the dendritic with the axonal action potential initiation zone of adult rat layer 5 pyramidal neurons. J Physiol 533: 447-466, 2001.
37. Letzkus JJ, Kampa BM, Stuart GJ. Learning rules for spike timing-dependent plasticity depend on dendritic synapse location. J Neurosci 26: 10420-10429, 2006.
38. 2+- channels, and GABA(A) receptors. Br J Anaesth 90: 199-211, 2003.
39. Liu J, Ji XQ, Zhu XZ. Comparison of psychic emergence reactions after (-+/-)-ketamine and (+-)-ketamine in mice. Life Sci 78: 1839-1844, 2006.
40. Macdonald RL, Rogers CJ, Twyman RE. Barbiturate regulation of kinetic properties of the GABAA receptor channel of mouse spinal neurones in culture. J Physiol 417: 483-500, 1989.
41. Maggi CA, Meli A. Suitability of urethane anesthesia for physiopharmacological investigations in various systems. Part 1. General considerations. Experientia 42: 109-114, 1986.
42. Margrie TW, Brecht M, Sakmann B. In vivo, low-resistance, whole-cell recordings from neurons in the anaesthetized and awake mammalian brain. Pfluegers Arch 444: 491-498, 2002.
43. Parker I, Gundersen CB, Miledi R. Actions of pentobarbital on rat brain receptors expressed in Xenopus oocytes. J Neurosci 6: 2290-2297, 1986.
44. Pei X, Volgushev M, Vidyasagar TR, Creutzfeldt OD. Whole cell recording and conductance measurements in cat visual cortex in-vivo. Neuroreport 2: 485-488, 1991.
45. Pérez-Garci E, Gassmann M, Bettler B, Larkum ME. The GABA(B1b) isoform mediates long-lasting inhibition of dendritic Ca(2+-) spikes in layer 5 somatosensory pyramidal neurons. Neuron 50: 603-616, 2006.
46. Pittson S, Himmel AM, MacIver MB. Multiple synaptic and membrane sites of anesthetic action in the CA1 region of rat hippocampal slices. BMC Neurosci 5: 52-59, 2004.
47. Richards CD. Anaesthetic modulation of synaptic transmission in the mammalian CNS. Br J Anaesth 89: 79-90, 2002.
48. Rojas MJ, Navas JA, Rector DM. Evoked response potential markers for anesthetic and behavioral states. Am J Physiol Regul Integr Comp Physiol 291: R189-R196, 2006.
49. Rowland LM. Subanesthetic ketamine: how it alters physiology and behavior in humans. Aviat Space Environ Med 76: C52-C58, 2005.
50. Rudolph M, Pospischil M, Timofeev I, Destexhe A. Inhibition determines membrane potential dynamics and controls action potential generation in awake and sleeping cat cortex. J Neurosci 27: 5280-5290, 2007.
51. Sceniak MP, MacIver MB. Cellular actions of urethane on rat visual cortical neurons in vitro. J Neurophysiol 95: 3865-3874, 2006.
52. Schiller J, Schiller Y, Stuart G, Sakmann B. Calcium action potentials restricted to distal apical dendrites of rat neocortical pyramidal neurons. J Physiol 505: 605-616, 1997.
53. Schnoebel R, Wolff M, Peters SC, Brau ME, Scholz A, Hempelmann G, Olschewski H, Olschewski A. Ketamine impairs excitability in superficial dorsal horn neurones by blocking sodium and voltage-gated potassium currents. Br J Pharmacol 146: 826-833, 2005.
54. Scholfield CN. Potentiation of inhibition by general anaesthetics in neurones of the olfactory cortex in vitro. Pfluegers Arch 383: 249-255, 1980.
55. Schwartz DD, Clark TP. Affinity of detomidine, medetomidine and xylazine for alpha-2 adrenergic receptor subtypes. J Vet Pharmacol Ther 21: 107-111, 1998.
56. Schwindt P, Crill W. Mechanisms underlying burst and regular spiking evoked by dendritic depolarization in layer 5 cortical pyramidal neurons. J Neurophysiol 81: 1341-1354, 1999.
57. Shiraishi M, Harris RA. Effects of alcohols and anesthetics on recombinant voltage-gated Na- channels. J Pharmacol Exp Ther 309: 987-994, 2004.
58. Sjöström PJ, Häusser M. A cooperative switch determines the sign of synaptic plasticity in distal dendrites of neocortical pyramidal neurons. Neuron 51: 227-238, 2006.
59. Svoboda K, Denk W, Kleinfeld D, Tank DW. In vivo dendritic calcium dynamics in neocortical pyramidal neurons. Nature 385: 161-165, 1997.
60. 2+- current in adult rat sensory neurons: effects of anticonvulsant and anesthetic agents. J Neurophysiol 79: 240-252, 1998.
61. Todorovic SM, Perez-Reyes E, Lingle CJ. Anticonvulsants but not general anesthetics have differential blocking effects on different T-type current variants. Mol Pharmacol 58: 98-108, 2000.
62. Urban BW. Current assessment of targets and theories of anaesthesia. Br J Anaesth 89: 167-183, 2002.
63. Vahle-Hinz C, Detsch O. What can in vivo electrophysiology in animal models tell us about mechanisms of anaesthesia? Br J Anaesth 89: 123-142, 2002.
64. Wang M, Ramos BP, Paspalas CD, Shu Y, Simen A, Duque A, Vijayraghavan S, Brennan A, Dudley A, Nou E, Mazer JA, McCormick DA, Arnsten AF. Alpha2A-adrenoceptors strengthen working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex. Cell 129: 397-410, 2007.
65. Wartenberg HC, Urban BW, Duch DS. Distinct molecular sites of anaesthetic action: pentobarbital block of human brain sodium channels is alleviated by removal of fast inactivation. Br J Anaesth 82: 74-80, 1999.
66. Waters J, Helmchen F. Boosting of action potential backpropagation by neocortical network activity in vivo. J Neurosci 24: 11127-11136, 2004.
67. 2+- influx into dendritic tufts of layer 2/3 neocortical pyramidal neurons in vitro and in vivo. J Neurosci 23: 8558-8567, 2003.
68. Williams SR, Stuart GJ. Mechanisms and consequences of action potential burst firing in rat neocortical pyramidal neurons. J Physiol 521: 467-482, 1999.
69. Wong RK, Prince DA. Participation of calcium spikes during intrinsic burst firing in hippocampal neurons. Brain Res 159: 385-390, 1978.
70. Yamakura T, Chavez-Noriega LE, Harris RA. Subunit-dependent inhibition of human neuronal nicotinic acetylcholine receptors and other ligand-gated ion channels by dissociative anesthetics ketamine and dizocilpine. Anesthesiology 92: 1144-1153, 2000.
71. Zhou ZS, Zhao ZQ. Ketamine blockage of both tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels of rat dorsal root ganglion neurons. Brain Res Bull 52: 427-433, 2000.
72. 2+- action potentials in adult rat tuft dendrites. J Physiol 526: 571-587, 2000.
73. Zhu JJ, Connors BW. Intrinsic firing patterns and whisker-evoked synaptic responses of neurons in the rat barrel cortex. J Neurophysiol 81: 1171-1183, 1999.