Subunit-dependent inhibition of human neuronal nicotinic acetylcholine receptors and other ligand-gated ion channels by dissociative anesthetics ketamine and dizocilpine

Anesthesiology

Volumn 92, Issue 4, 2000, Pages 1144-1153

  Yamakura, Tomohiro ^a   Chavez Noriega, Laura E ^b   Harris, R Adron ^c  

^a NIIGATA UNIVERSITY   (Japan)

^b MERCK RESEARCH LABORATORIES   (United States)

^c UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Cholinergic; Electrophysiology; Serotonin

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; CHOLINERGIC RECEPTOR STIMULATING AGENT; DIZOCILPINE; GLYCINE RECEPTOR; ION CHANNEL; KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NICOTINIC RECEPTOR; RECEPTOR SUBUNIT; SEROTONIN; SEROTONIN 3 RECEPTOR;

ANESTHESIA; ANIMAL CELL; ARTICLE; COMPETITIVE INHIBITION; ELECTROPHYSIOLOGY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; VOLTAGE CLAMP; XENOPUS LAEVIS;

EID: 0034126875     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-200004000-00033     Document Type: Article

References (45)

1. Yamakura T, Mori H, Masaki H, Shimoji K, Mishina M: Different sensitivities of NMDA receptor channel subtypes to non-competitive antagonists. NeuroReport 1993; 4:687-90
2. Grant IS, Nimmo WS, McNicol LR, Clements JA: Ketamine disposition in children and adults. Br J Anaesth 1983; 55:1107-11
3. Koek W, Woods JH, Winger GD: MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys. J Pharmacol Exp Ther 1988; 245:969-74
4. Kelland MD, Soltis RP, Boldry RC, Walters JR: Behavioral and electrophysiological comparison of ketamine with dizocilpine in the rat. Physiol Behav 1993; 54:547-54
5. Franks NP, Lieb WR: Molecular and cellular mechanisms of general anaesthesia. Nature 1994; 367:607-14
6. Sargent PB: The diversity of neuronal nicotinic acetylcholine receptors. Annu Rev Neurosci 1993; 16:403-43
7. Gotti C, Fornasari D, Clementi F: Human neuronal nicotinic receptors. Prog Neurobiol 1997; 53:199-237
8. Role LW, Berg DK: Nicotinic receptors in the development and modulation of CNS synapses. Neuron 1996; 16:1077-85
9. Zoli M, Lena C, Picciotto MR, Changeux JP: Identification of four classes of brain nicotinic receptors using β2 mutant mice. J Neurosci 1998; 18:4461-72
10. Chavez-Noriega LE, Crona JH, Washburn MS, Urrutia A, Elliott KJ, Johnson EC: Pharmacological characterization of recombinant human neuronal nicotinic acetylcholine receptors hα2β2, hα2β4, hα3β2, hα3β4, hα4β2, hα4β4 and hα7 expressed in Xenopus oocytes. J Pharmacol Exp Ther 1997; 280:346-56
11. Maleque MA, Warnick JE, Albuquerque EX: The mechanism and site of action of ketamine on skeletal muscle. J Pharmacol Exp Ther 1981; 219:638-45
12. Wachtel RE, Wegrzynowicz ES: Kinetics of nicotinic acetylcholine ion channels in the presence of intravenous anaesthetics and induction agents. Br J Pharmacol 1992; 106:623-7
13. Ramoa AS, Alkondon M, Aracava Y, Irons J, Lunt GG, Deshpande SS, Wonnacott S, Aronstam RS, Albuquerque EX: The anticonvulsant MK-801 interacts with peripheral and central nicotinic acetylcholine receptor ion channels. J Pharmacol Exp Ther 1990; 254:71-82
14. Amador M, Dani JA: MK-801 inhibition of nicotinic acetylcholine receptor channels. Synapse 1991; 7:207-15
15. 2x purinoceptors in PC12 cells. Anesth Analg 1999; 88:174-80
16. Halliwell RF, Peters JA, Lambert JJ: The mechanism of action and pharmacological specificity of the anticonvulsant NMDA antagonist MK-801: A voltage clamp study on neuronal cells in culture. Br J Pharmacol 1989; 96:480-94
17. Connolly J, Boulter J, Heinemann SF: α4-2β2 and other nicotinic acetylcholine receptor subtypes as targets of psychoactive and addictive drugs. Br J Pharmacol 1992; 105:657-66
18. Briggs CA, McKenna DG: Effect of MK-801 at the human α7 nicotinic acetylcholine receptor. Neuropharmacology 1996; 35:407-14
19. Elliott KJ, Ellis SB, Berckhan KJ, Urrutia A, Chavez-Noriega LE, Johnson EC, Velicelebi G, Harpold MM: Comparative structure of human neuronal α2-α7 and β2-β4 nicotinic acetylcholine receptor subunits and functional expression of the α2, α3, α4, α7, β2, and β4 subunits. J Mol Neurosci 1996; 7:217-28
20. 3 receptor, a serotoningated ion channel. Science 1991; 254:432-7
21. Hadingham KL, Wingrove PB, Wafford KA, Bain C, Kemp JA, Palmer KJ, Wilson AW, Wilcox AS, Sikela JM, Ragan CI, Whiting PJ: Role of the β subunit in determining the pharmacology of human γ-aminobutyric acid type A receptors. Mol Pharmacol 1993; 44:1211-8
22. Grenningloh G, Schmieden V, Schofield PR, Seeburg PH, Siddique T, Mohandas TK, Becker CM, Betz H: Alpha subunit variants of the human glycine receptor: Primary structures, functional expression and chromosomal localization of the corresponding genes. EMBO J 1990; 9:771-6
23. Cardoso RA, Yamakura T, Brozowski SJ, Chavez-Noriega LE, Harris RA: Human neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes predict efficacy of halogenated compounds that disobey the Meyer-Overton rule. ANESTHESIOLOGY 1999; 91:1370-7
24. A receptors expressed by Xenopus oocytes: Lack of involvement of intracellular calcium. J Pharmacol Exp Ther 1992; 263:569-78
25. Mak CK, Avalos M, Randall PK, Kwan SW, Abell CW, Neumeyer JL, Whisennand R, Wilcox RE: Improved models for pharmacological null experiments: Calculation of drug efficacy at recombinant D1A dopamine receptors stably expressed in clonal cell lines. Neuropharmacology 1996; 35:549-70
26. Flood P, Ramirez-Latorre J, Role L: α4β2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but α7-type nicotinic acetylcholine receptors are unaffected. ANESTHESIOLOGY 1997; 86:859-65
27. Lipton SA, Aizenman E, Loring RH: Neural nicotinic acetylcholine responses in solitary mammalian retinal ganglion cells. Pflugers Arch 1987; 410:37-43
28. Huettner JE, Bean BP: Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: Selective binding to open channels. Proc Natl Acad Sci USA 1988; 85:1307-11
29. MacDonald JF, Miljkovic Z, Pennefather P: Use-dependent block of excitatory amino acid currents in cultured neurons by ketamine. J Neurophysiol 1987; 58:251-66
30. Scheller M, Bufler J, Hertle I, Schneck HJ, Franke C, Kochs E: Ketamine blocks currents through mammalian nicotinic acetylcholine receptor channels by interaction with both the open and the closed state. Anesth Analg 1996; 83:830-6
31. Childs AM, Evans RH, Watkins JC: The pharmacological selectivity of three NMDA antagonists. Eur J Pharmacol 1988; 145:81-6
32. 3 receptor-mediated currents in rabbit nodose ganglion neurones. Br J Pharmacol 1991; 103:1623-5
33. 3 receptor of N1E-115 neuroblastoma cells. Naunyn Schmiedebergs Arch Pharmacol 1993; 347: 125-32
34. Nishimura M, Sato K, Okada T, Yoshiya I, Schloss P, Shimada S, Tohyama M: Ketamine inhibits monoamine transporters expressed in human embryonic kidney 293 cells. ANESTHESIOLOGY 1998; 88:768-74
35. Reich DL, Silvay G: Ketamine: An update on the first twenty-five years of clinical experience. Can J Anaesth 1989; 36:186-97
36. Cohen ML, Chan SL, Way WL, Trevor AJ: Distribution in the brain and metabolism of ketamine in the rat after intravenous administration. ANESTHESIOLOGY 1973; 39:370-6
37. Vezzani A, Serafini R, Stasi MA, Caccia S, Conti I, Tridico RV, Samanin R: Kinetics of MK-801 and its effect on quinolinic acid-induced seizures and neurotoxicity in rats. J Pharmacol Exp Ther 1989; 249:278-83
38. Dayton PG, Stiller RL, Cook DR, Perel JM: The binding of ketamine to plasma proteins: Emphasis on human plasma. Eur J Clin Pharmacol 1983; 24:825-31
39. Willis CL, Brazell C, Foster AC: Plasma and CSF levels of dizocilpine (MK-801) required for neuroprotection in the quinolinate-injected rat striatum. Eur J Pharmacol 1991; 196:285-90
40. Sumikawa K, Matsumoto T, Amenomori Y, Hirano H, Amakata Y: Selective actions of intravenous anesthetics on nicotinic and muscarinic-receptor-mediated responses of the dog adrenal medulla. ANESTHESIOLOGY 1983; 59:412-6
41. Eger II EI, Ionescu P, Laster MJ, Gong D, Hudlicky T, Kendig JJ, Harris RA, Trudell JR, Pohorille A: Minimum alveolar anesthetic concentration of fluorinated alkanols in rats: Relevance to theories of narcosis. Anesth Analg 1999; 88:867-76
42. Gonzales EL, Harris RA, Dunwiddie TV: The effects of alkanols on human neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes correlates with molecular volume. Soc Neurosci Abstr 1999; 25:1074
43. A receptors: Relevance to theories of narcosis. Anesth Analg 1999; 88:877-83
44. A receptor-mediated currents: Lack of subunit specificity. Eur J Pharmacol 1994; 268:209-14
45. Cardoso RA, Brozowski SJ, Chavez-Noriega LE, Harpold M, Valenzuela CF, Harris RA: Effects of ethanol on recombinant human neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. J Pharmacol Exp Ther 1999; 289:774-80