Ketamine impairs excitability in superficial dorsal horn neurones by blocking sodium and voltage-gated potassium currents

British Journal of Pharmacology

Volumn 146, Issue 6, 2005, Pages 826-833

  Schnoebel, Rose ^a   Wolff, Matthias ^a   Peters, Saskia C ^b   Bräu, Michael E ^a   Scholz, Andreas ^b   Hempelmann, Gunter ^a   Olschewski, Horst ^c   Olschewski, Andrea ^a  

^a UNIVERSITY HOSPITAL GIESSEN   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Action potential; Electrophysiology; Ion channels; Pain; Pharmacology; Sensory neurones

Indexed keywords

KETAMINE; POTASSIUM CHANNEL BLOCKING AGENT; SODIUM CHANNEL BLOCKING AGENT; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; FREQUENCY ANALYSIS; IC 50; LUMBAR SPINAL CORD; MALE; NERVE CELL; NERVE CELL EXCITABILITY; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; SODIUM CURRENT; SPINAL ANESTHESIA; SPINAL CORD DORSAL HORN; STEREOCHEMISTRY;

ACTION POTENTIALS; ANESTHETICS, DISSOCIATIVE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; KETAMINE; PATCH-CLAMP TECHNIQUES; POSTERIOR HORN CELLS; POTASSIUM CHANNELS, VOLTAGE-GATED; RATS; SODIUM CHANNELS; SPINAL CORD;

EID: 27744578164     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706385     Document Type: Article

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