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Volumn 38, Issue 4, 2008, Pages 566-578

Immunogenetic characteristics of immunoglobulin E in allergic disease

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN E; IMMUNOGLOBULIN E ANTIBODY;

EID: 40949098183     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2008.02941.x     Document Type: Review
Times cited : (19)

References (88)
  • 1
    • 0033836197 scopus 로고    scopus 로고
    • Increasing prevalence of specific IgE to aeroallergens in an adult population: Two cross-sectional surveys 8 years apart: The Copenhagen Allergy Study
    • Linneberg A, Nielsen NH, Madsen F, Frolund L, Dirksen A, Jorgensen T. Increasing prevalence of specific IgE to aeroallergens in an adult population: two cross-sectional surveys 8 years apart: the Copenhagen Allergy Study. J Allergy Clin Immunol 2000 106 : 247 52.
    • (2000) J Allergy Clin Immunol , vol.106 , pp. 247-52
    • Linneberg, A.1    Nielsen, N.H.2    Madsen, F.3    Frolund, L.4    Dirksen, A.5    Jorgensen, T.6
  • 2
    • 0025969722 scopus 로고
    • Frequency analysis of IgE-secreting B lymphocytes in persons with normal or elevated serum IgE levels
    • King CL, Poindexter RW, Ragunathan J, Fleisher TA, Ottesen EA, Nutman TB. Frequency analysis of IgE-secreting B lymphocytes in persons with normal or elevated serum IgE levels. J Immunol 1991 146 : 1478 83.
    • (1991) J Immunol , vol.146 , pp. 1478-83
    • King, C.L.1    Poindexter, R.W.2    Ragunathan, J.3    Fleisher, T.A.4    Ottesen, E.A.5    Nutman, T.B.6
  • 3
    • 33746217857 scopus 로고    scopus 로고
    • Inefficient processing of mRNA for the membrane form of IgE is a genetic mechanism to limit recruitment of IgE-secreting cells
    • Karnowski A, Achatz-Straussberger G, Klockenbusch C, Achatz G, Lamers MC. Inefficient processing of mRNA for the membrane form of IgE is a genetic mechanism to limit recruitment of IgE-secreting cells. Eur J Immunol 2006 36 : 1917 25.
    • (2006) Eur J Immunol , vol.36 , pp. 1917-25
    • Karnowski, A.1    Achatz-Straussberger, G.2    Klockenbusch, C.3    Achatz, G.4    Lamers, M.C.5
  • 4
    • 0034691520 scopus 로고    scopus 로고
    • Structure of the Fc fragment of human IgE bound to its high-affinity receptor Fc epsilonRI alpha
    • Garman SC, Wurzburg BA, Tarchevskaya SS, Kinet JP, Jardetzky TS. Structure of the Fc fragment of human IgE bound to its high-affinity receptor Fc epsilonRI alpha. Nature 2000 406 : 259 66.
    • (2000) Nature , vol.406 , pp. 259-66
    • Garman, S.C.1    Wurzburg, B.A.2    Tarchevskaya, S.S.3    Kinet, J.P.4    Jardetzky, T.S.5
  • 5
    • 0036308980 scopus 로고    scopus 로고
    • The crystal structure of IgE Fc reveals an asymmetrically bent conformation
    • Wan T, Beavil RL, Fabiane SM et al. The crystal structure of IgE Fc reveals an asymmetrically bent conformation. Nat Immunol 2002 3 : 681 6.
    • (2002) Nat Immunol , vol.3 , pp. 681-6
    • Wan, T.1    Beavil, R.L.2    Fabiane, S.M.3
  • 6
    • 0030006070 scopus 로고    scopus 로고
    • Clonal selection and learning in the antibody system
    • Rajewsky K. Clonal selection and learning in the antibody system. Nature 1996 381 : 751 8.
    • (1996) Nature , vol.381 , pp. 751-8
    • Rajewsky, K.1
  • 7
    • 0036212917 scopus 로고    scopus 로고
    • Molecular mechanism of class switch recombination: Linkage with somatic hypermutation
    • Honjo T, Kinoshita K, Muramatsu M. Molecular mechanism of class switch recombination: linkage with somatic hypermutation. Annu Rev Immunol 2002 20 : 165 96.
    • (2002) Annu Rev Immunol , vol.20 , pp. 165-96
    • Honjo, T.1    Kinoshita, K.2    Muramatsu, M.3
  • 9
    • 33745498089 scopus 로고    scopus 로고
    • DNA repair in antibody somatic hypermutation
    • Casali P, Pal Z, Xu Z, Zan H. DNA repair in antibody somatic hypermutation. Trends Immunol 2006 27 : 313 21.
    • (2006) Trends Immunol , vol.27 , pp. 313-21
    • Casali, P.1    Pal, Z.2    Xu, Z.3    Zan, H.4
  • 10
    • 0027227311 scopus 로고
    • Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes
    • Betz AG, Neuberger MS, Milstein C. Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes. Immunol Today 1993 14 : 405 11.
    • (1993) Immunol Today , vol.14 , pp. 405-11
    • Betz, A.G.1    Neuberger, M.S.2    Milstein, C.3
  • 11
    • 0031945415 scopus 로고    scopus 로고
    • Analysis of the targeting of the hypermutational machinery and the impact of subsequent selection on the distribution of nucleotide changes in human VHDJH rearrangements
    • Dorner T, Foster SJ, Brezinschek HP, Lipsky PE. Analysis of the targeting of the hypermutational machinery and the impact of subsequent selection on the distribution of nucleotide changes in human VHDJH rearrangements. Immunol Rev 1998 162 : 161 71.
    • (1998) Immunol Rev , vol.162 , pp. 161-71
    • Dorner, T.1    Foster, S.J.2    Brezinschek, H.P.3    Lipsky, P.E.4
  • 12
    • 0024327901 scopus 로고
    • Stable expression and somatic hypermutation of antibody V regions in B-cell developmental pathways
    • Kocks C, Rajewsky K. Stable expression and somatic hypermutation of antibody V regions in B-cell developmental pathways. Annu Rev Immunol 1989 7 : 537 59.
    • (1989) Annu Rev Immunol , vol.7 , pp. 537-59
    • Kocks, C.1    Rajewsky, K.2
  • 13
    • 0035881820 scopus 로고    scopus 로고
    • The intrinsic hypermutability of antibody heavy and light chain genes decays exponentially
    • Rada C, Milstein C. The intrinsic hypermutability of antibody heavy and light chain genes decays exponentially. EMBO J 2001 20 : 4570 6.
    • (2001) EMBO J , vol.20 , pp. 4570-6
    • Rada, C.1    Milstein, C.2
  • 15
    • 0035974865 scopus 로고    scopus 로고
    • Immunology. Antibody alterations
    • Martin A, Scharff MD. Immunology. Antibody alterations. Nature 2001 412 : 870 1.
    • (2001) Nature , vol.412 , pp. 870-1
    • Martin, A.1    Scharff, M.D.2
  • 16
    • 33745323376 scopus 로고    scopus 로고
    • Trends in antibody sequence changes during the somatic hypermutation process
    • Clark LA, Ganesan S, Papp S, van Vlijmen HW. Trends in antibody sequence changes during the somatic hypermutation process. J Immunol 2006 177 : 333 40.
    • (2006) J Immunol , vol.177 , pp. 333-40
    • Clark, L.A.1    Ganesan, S.2    Papp, S.3    Van Vlijmen, H.W.4
  • 17
    • 33745053586 scopus 로고    scopus 로고
    • Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production
    • Ippolito GC, Schelonka RL, Zemlin M et al. Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production. J Exp Med 2006 203 : 1567 78.
    • (2006) J Exp Med , vol.203 , pp. 1567-78
    • Ippolito, G.C.1    Schelonka, R.L.2    Zemlin, M.3
  • 18
    • 0035958618 scopus 로고    scopus 로고
    • Role of receptor editing and revision in shaping the B and T lymphocyte repertoire
    • Kouskoff V, Nemazee D. Role of receptor editing and revision in shaping the B and T lymphocyte repertoire. Life Sci 2001 69 : 1105 13.
    • (2001) Life Sci , vol.69 , pp. 1105-13
    • Kouskoff, V.1    Nemazee, D.2
  • 19
    • 0034608480 scopus 로고    scopus 로고
    • Receptor revision of immunoglobulin heavy chain variable region genes in normal human B lymphocytes
    • Wilson PC, Wilson K, Liu YJ, Banchereau J, Pascual V, Capra JD. Receptor revision of immunoglobulin heavy chain variable region genes in normal human B lymphocytes. J Exp Med 2000 191 : 1881 94.
    • (2000) J Exp Med , vol.191 , pp. 1881-94
    • Wilson, P.C.1    Wilson, K.2    Liu, Y.J.3    Banchereau, J.4    Pascual, V.5    Capra, J.D.6
  • 20
    • 33646521258 scopus 로고    scopus 로고
    • Regulatory mechanisms of immunoglobulin e synthesis by human B cells
    • Yanagihara Y. Regulatory mechanisms of immunoglobulin E synthesis by human B cells. Clin Exp Allergy Rev 2006 6 : 101 5.
    • (2006) Clin Exp Allergy Rev , vol.6 , pp. 101-5
    • Yanagihara, Y.1
  • 21
    • 0023278330 scopus 로고
    • Canonical structures for the hypervariable regions of immunoglobulins
    • Chothia C, Lesk AM. Canonical structures for the hypervariable regions of immunoglobulins. J Mol Biol 1987 196 : 901 17.
    • (1987) J Mol Biol , vol.196 , pp. 901-17
    • Chothia, C.1    Lesk, A.M.2
  • 22
    • 0032568959 scopus 로고    scopus 로고
    • Automated classification of antibody complementarity determining region 3 of the heavy chain (H3) loops into canonical forms and its application to protein structure prediction
    • Oliva B, Bates PA, Querol E, Aviles FX, Sternberg MJ. Automated classification of antibody complementarity determining region 3 of the heavy chain (H3) loops into canonical forms and its application to protein structure prediction. J Mol Biol 1998 279 : 1193 210.
    • (1998) J Mol Biol , vol.279 , pp. 1193-210
    • Oliva, B.1    Bates, P.A.2    Querol, E.3    Aviles, F.X.4    Sternberg, M.J.5
  • 23
    • 33748138991 scopus 로고    scopus 로고
    • Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations
    • Lieber MR, Yu K, Raghavan SC. Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations. DNA Repair (Amsterdam) 2006 5 : 1234 45.
    • (2006) DNA Repair (Amsterdam) , vol.5 , pp. 1234-45
    • Lieber, M.R.1    Yu, K.2    Raghavan, S.C.3
  • 24
    • 0025781883 scopus 로고
    • Multiple mechanisms participate in the generation of diversity of human H chain CDR3 regions
    • Sanz I. Multiple mechanisms participate in the generation of diversity of human H chain CDR3 regions. J Immunol 1991 147 : 1720 9.
    • (1991) J Immunol , vol.147 , pp. 1720-9
    • Sanz, I.1
  • 26
    • 0031013906 scopus 로고    scopus 로고
    • Pattern of usage and somatic hypermutation in the V(H)5 gene segments of a patient with asthma: Implications for IgE
    • Snow RE, Chapman CJ, Frew AJ, Holgate ST, Stevenson FK. Pattern of usage and somatic hypermutation in the V(H)5 gene segments of a patient with asthma: implications for IgE. Eur J Immunol 1997 27 : 162 70.
    • (1997) Eur J Immunol , vol.27 , pp. 162-70
    • Snow, R.E.1    Chapman, C.J.2    Frew, A.J.3    Holgate, S.T.4    Stevenson, F.K.5
  • 27
    • 33745872580 scopus 로고    scopus 로고
    • Paucity of V-D-D-J rearrangements and VH replacement events in lupus prone and nonautoimmune TdT-/- and TdT+/+ mice
    • Watson LC, Moffatt-Blue CS, McDonald RZ et al. Paucity of V-D-D-J rearrangements and VH replacement events in lupus prone and nonautoimmune TdT-/- and TdT+/+ mice. J Immunol 2006 177 : 1120 8.
    • (2006) J Immunol , vol.177 , pp. 1120-8
    • Watson, L.C.1    Moffatt-Blue, C.S.2    McDonald, R.Z.3
  • 28
    • 0031832662 scopus 로고    scopus 로고
    • IMGT, the International ImMunoGeneTics database
    • Lefranc MP, Giudicelli V, Busin C et al. IMGT, the International ImMunoGeneTics database. Nucleic Acids Res 1998 26 : 297 303.
    • (1998) Nucleic Acids Res , vol.26 , pp. 297-303
    • Lefranc, M.P.1    Giudicelli, V.2    Busin, C.3
  • 29
    • 0242469155 scopus 로고    scopus 로고
    • Immunoglobulin gene rearrangement, repertoire diversity, and the allergic response
    • Collins AM, Sewell WA, Edwards MR. Immunoglobulin gene rearrangement, repertoire diversity, and the allergic response. Pharmacol Ther 2003 100 : 157 70.
    • (2003) Pharmacol Ther , vol.100 , pp. 157-70
    • Collins, A.M.1    Sewell, W.A.2    Edwards, M.R.3
  • 30
    • 0033711628 scopus 로고    scopus 로고
    • Diversity in the CDR3 region of V(H) is sufficient for most antibody specificities
    • Xu JL, Davis MM. Diversity in the CDR3 region of V(H) is sufficient for most antibody specificities. Immunity 2000 13 : 37 45.
    • (2000) Immunity , vol.13 , pp. 37-45
    • Xu, J.L.1    Davis, M.M.2
  • 31
    • 0027460052 scopus 로고
    • Molecular evolution of the human immunoglobulin e response: High incidence of shared mutations and clonal relatedness among epsilon VH5 transcripts from three unrelated patients with atopic dermatitis
    • van der Stoep N, van der Linden J, Logtenberg T. Molecular evolution of the human immunoglobulin E response: high incidence of shared mutations and clonal relatedness among epsilon VH5 transcripts from three unrelated patients with atopic dermatitis. J Exp Med 1993 177 : 99 107.
    • (1993) J Exp Med , vol.177 , pp. 99-107
    • Van Der Stoep, N.1    Van Der Linden, J.2    Logtenberg, T.3
  • 32
    • 0028989605 scopus 로고
    • Analysis of Ig VH region genes encoding IgE antibodies in splenic B lymphocytes of a patient with asthma
    • Snow RE, Chapman CJ, Frew AJ, Holgate ST, Stevenson FK. Analysis of Ig VH region genes encoding IgE antibodies in splenic B lymphocytes of a patient with asthma. J Immunol 1995 154 : 5576 81.
    • (1995) J Immunol , vol.154 , pp. 5576-81
    • Snow, R.E.1    Chapman, C.J.2    Frew, A.J.3    Holgate, S.T.4    Stevenson, F.K.5
  • 34
    • 0033407143 scopus 로고    scopus 로고
    • Analysis of immunoglobulin e VH transcripts in a bronchial biopsy of an asthmatic patient confirms bias towards VH5, and indicates local clonal expansion, somatic mutation and isotype switch events
    • Snow RE, Djukanovic R, Stevenson FK. Analysis of immunoglobulin E VH transcripts in a bronchial biopsy of an asthmatic patient confirms bias towards VH5, and indicates local clonal expansion, somatic mutation and isotype switch events. Immunology 1999 98 : 646 51.
    • (1999) Immunology , vol.98 , pp. 646-51
    • Snow, R.E.1    Djukanovic, R.2    Stevenson, F.K.3
  • 35
    • 0030615094 scopus 로고    scopus 로고
    • VH genes expressed in peripheral blood IgE-producing B cells from patients with atopic dermatitis
    • Tilgner J, Golembowski S, Kersten B, Sterry W, Jahn S. VH genes expressed in peripheral blood IgE-producing B cells from patients with atopic dermatitis. Clin Exp Immunol 1997 107 : 528 35.
    • (1997) Clin Exp Immunol , vol.107 , pp. 528-35
    • Tilgner, J.1    Golembowski, S.2    Kersten, B.3    Sterry, W.4    Jahn, S.5
  • 36
    • 0031681234 scopus 로고    scopus 로고
    • Clonally related IgE and IgG4 transcripts in blood lymphocytes of patients with asthma reveal differing patterns of somatic mutation
    • Snow RE, Chapman CJ, Holgate ST, Stevenson FK. Clonally related IgE and IgG4 transcripts in blood lymphocytes of patients with asthma reveal differing patterns of somatic mutation. Eur J Immunol 1998 28 : 3354 61.
    • (1998) Eur J Immunol , vol.28 , pp. 3354-61
    • Snow, R.E.1    Chapman, C.J.2    Holgate, S.T.3    Stevenson, F.K.4
  • 37
    • 0029919595 scopus 로고    scopus 로고
    • Construction of a combinatorial IgE library from an allergic patient. Isolation and characterization of human IgE Fabs with specificity for the major timothy grass pollen allergen, Phl p 5
    • Steinberger P, Kraft D, Valenta R. Construction of a combinatorial IgE library from an allergic patient. Isolation and characterization of human IgE Fabs with specificity for the major timothy grass pollen allergen, Phl p 5. J Biol Chem 1996 271 : 10967 72.
    • (1996) J Biol Chem , vol.271 , pp. 10967-72
    • Steinberger, P.1    Kraft, D.2    Valenta, R.3
  • 39
    • 0037097646 scopus 로고    scopus 로고
    • Analysis of IgE antibodies from a patient with atopic dermatitis: Biased V gene usage and evidence for polyreactive IgE heavy chain complementarity- determining region 3
    • Edwards MR, Brouwer W, Choi CH, Ruhno J, Ward RL, Collins AM. Analysis of IgE antibodies from a patient with atopic dermatitis: biased V gene usage and evidence for polyreactive IgE heavy chain complementarity-determining region 3. J Immunol 2002 168 : 6305 13.
    • (2002) J Immunol , vol.168 , pp. 6305-13
    • Edwards, M.R.1    Brouwer, W.2    Choi, C.H.3    Ruhno, J.4    Ward, R.L.5    Collins, A.M.6
  • 40
    • 0242494188 scopus 로고    scopus 로고
    • Local somatic hypermutation and class switch recombination in the nasal mucosa of allergic rhinitis patients
    • Coker HA, Durham SR, Gould HJ. Local somatic hypermutation and class switch recombination in the nasal mucosa of allergic rhinitis patients. J Immunol 2003 171 : 5602 10.
    • (2003) J Immunol , vol.171 , pp. 5602-10
    • Coker, H.A.1    Durham, S.R.2    Gould, H.J.3
  • 41
    • 1642312176 scopus 로고    scopus 로고
    • VH gene usage in immunoglobulin e responses of seasonal rhinitis patients allergic to grass pollen is oligoclonal and antigen driven
    • Davies JM, O'Hehir RE. VH gene usage in immunoglobulin E responses of seasonal rhinitis patients allergic to grass pollen is oligoclonal and antigen driven. Clin Exp Allergy 2004 34 : 429 36.
    • (2004) Clin Exp Allergy , vol.34 , pp. 429-36
    • Davies, J.M.1    O'Hehir, R.E.2
  • 42
    • 3242734675 scopus 로고    scopus 로고
    • Characterization of VHepsilon gene expressed in PBL from children with atopic diseases: Detection of homologous VH1-69 derived transcripts from three unrelated patients
    • Bando Y, Shimizu A, Ra C. Characterization of VHepsilon gene expressed in PBL from children with atopic diseases: detection of homologous VH1-69 derived transcripts from three unrelated patients. Immunol Lett 2004 94 : 99 106.
    • (2004) Immunol Lett , vol.94 , pp. 99-106
    • Bando, Y.1    Shimizu, A.2    Ra, C.3
  • 43
    • 23244457657 scopus 로고    scopus 로고
    • Biased use of VH5 IgE-positive B cells in the nasal mucosa in allergic rhinitis
    • Coker HA, Harries HE, Banfield GK et al. Biased use of VH5 IgE-positive B cells in the nasal mucosa in allergic rhinitis. J Allergy Clin Immunol 2005 116 : 445 52.
    • (2005) J Allergy Clin Immunol , vol.116 , pp. 445-52
    • Coker, H.A.1    Harries, H.E.2    Banfield, G.K.3
  • 44
    • 33747790631 scopus 로고    scopus 로고
    • The human IgE-encoding transcriptome to assess antibody repertoires and repertoire evolution
    • Andreasson U, Flicker S, Lindstedt M et al. The human IgE-encoding transcriptome to assess antibody repertoires and repertoire evolution. J Mol Biol 2006 362 : 212 27.
    • (2006) J Mol Biol , vol.362 , pp. 212-27
    • Andreasson, U.1    Flicker, S.2    Lindstedt, M.3
  • 45
    • 34548329663 scopus 로고    scopus 로고
    • The IgE repertoire in PBMCs of atopic patients is characterized by individual rearrangements without variable region of the heavy immunoglobulin chain bias
    • Lim A, Luderschmidt S, Weidinger A et al. The IgE repertoire in PBMCs of atopic patients is characterized by individual rearrangements without variable region of the heavy immunoglobulin chain bias. J Allergy Clin Immunol 2007 120 : 696 706.
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 696-706
    • Lim, A.1    Luderschmidt, S.2    Weidinger, A.3
  • 46
    • 17044377561 scopus 로고    scopus 로고
    • Allergen drives class switching to IgE in the nasal mucosa in allergic rhinitis
    • Takhar P, Smurthwaite L, Coker HA et al. Allergen drives class switching to IgE in the nasal mucosa in allergic rhinitis. J Immunol 2005 174 : 5024 32.
    • (2005) J Immunol , vol.174 , pp. 5024-32
    • Takhar, P.1    Smurthwaite, L.2    Coker, H.A.3
  • 47
    • 0032101960 scopus 로고    scopus 로고
    • In vivo inflammatory response to a prototypic B cell superantigen: Elicitation of an Arthus reaction by staphylococcal protein a
    • Kozlowski LM, Li W, Goldschmidt M, Levinson AI. In vivo inflammatory response to a prototypic B cell superantigen: elicitation of an Arthus reaction by staphylococcal protein A. J Immunol 1998 160 : 5246 52.
    • (1998) J Immunol , vol.160 , pp. 5246-52
    • Kozlowski, L.M.1    Li, W.2    Goldschmidt, M.3    Levinson, A.I.4
  • 48
    • 0023720830 scopus 로고
    • MHC class II restriction specificity of cloned human T lymphocytes reactive with Dermatophagoides farinae (house dust mite)
    • O'Hehir RE, Eckels DD, Frew AJ, Kay AB, Lamb JR. MHC class II restriction specificity of cloned human T lymphocytes reactive with Dermatophagoides farinae (house dust mite). Immunology 1988 64 : 627 31.
    • (1988) Immunology , vol.64 , pp. 627-31
    • O'Hehir, R.E.1    Eckels, D.D.2    Frew, A.J.3    Kay, A.B.4    Lamb, J.R.5
  • 49
    • 0025003823 scopus 로고
    • Direct evidence for a functional role of HLA-DRB1 and - DRB3 gene products in the recognition of Dermatophagoides spp. (house dust mite) by helper T lymphocytes
    • O'Hehir RE, Mach B, Berte C et al. Direct evidence for a functional role of HLA-DRB1 and - DRB3 gene products in the recognition of Dermatophagoides spp. (house dust mite) by helper T lymphocytes. Int Immunol 1990 2 : 885 92.
    • (1990) Int Immunol , vol.2 , pp. 885-92
    • O'Hehir, R.E.1    MacH, B.2    Berte, C.3
  • 50
    • 0033796926 scopus 로고    scopus 로고
    • Immunoglobulin e antibodies of atopic individuals exhibit a broad usage of VH-gene families
    • Eibensteiner P, Spitzauer S, Steinberger P, Kraft D, Valenta R. Immunoglobulin E antibodies of atopic individuals exhibit a broad usage of VH-gene families. Immunology 2000 101 : 112 9.
    • (2000) Immunology , vol.101 , pp. 112-9
    • Eibensteiner, P.1    Spitzauer, S.2    Steinberger, P.3    Kraft, D.4    Valenta, R.5
  • 51
    • 0036217975 scopus 로고    scopus 로고
    • Origins and functions of B-1 cells with notes on the role of CD5
    • Berland R, Wortis HH. Origins and functions of B-1 cells with notes on the role of CD5. Annu Rev Immunol 2002 20 : 253 300.
    • (2002) Annu Rev Immunol , vol.20 , pp. 253-300
    • Berland, R.1    Wortis, H.H.2
  • 52
    • 0029063311 scopus 로고
    • Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction
    • Brezinschek HP, Brezinschek RI, Lipsky PE. Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction. J Immunol 1995 155 : 190 202.
    • (1995) J Immunol , vol.155 , pp. 190-202
    • Brezinschek, H.P.1    Brezinschek, R.I.2    Lipsky, P.E.3
  • 53
    • 0027181619 scopus 로고
    • Molecular analysis of IgE H-chain transcripts expressed in vivo by peripheral blood lymphocytes from normal and atopic individuals
    • Efremov DG, Batista FD, Burrone OR. Molecular analysis of IgE H-chain transcripts expressed in vivo by peripheral blood lymphocytes from normal and atopic individuals. J Immunol 1993 151 : 2195 207.
    • (1993) J Immunol , vol.151 , pp. 2195-207
    • Efremov, D.G.1    Batista, F.D.2    Burrone, O.R.3
  • 54
    • 33845952641 scopus 로고    scopus 로고
    • Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma
    • Takhar P, Corrigan CJ, Smurthwaite L et al. Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma. J Allergy Clin Immunol 2007 119 : 213 8.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 213-8
    • Takhar, P.1    Corrigan, C.J.2    Smurthwaite, L.3
  • 56
    • 0026099589 scopus 로고
    • Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes
    • Yamada M, Wasserman R, Reichard BA, Shane S, Caton AJ, Rovera G. Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes. J Exp Med 1991 173 : 395 407.
    • (1991) J Exp Med , vol.173 , pp. 395-407
    • Yamada, M.1    Wasserman, R.2    Reichard, B.A.3    Shane, S.4    Caton, A.J.5    Rovera, G.6
  • 57
    • 0026567277 scopus 로고
    • Use of family specific leader region primers for PCR amplification of the human heavy chain variable region gene repertoire
    • Campbell MJ, Zelenetz AD, Levy S, Levy R. Use of family specific leader region primers for PCR amplification of the human heavy chain variable region gene repertoire. Mol Immunol 1992 29 : 193 203.
    • (1992) Mol Immunol , vol.29 , pp. 193-203
    • Campbell, M.J.1    Zelenetz, A.D.2    Levy, S.3    Levy, R.4
  • 58
    • 0026785856 scopus 로고
    • The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops
    • Tomlinson IM, Walter G, Marks JD, Llewelyn MB, Winter G. The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops. J Mol Biol 1992 227 : 776 98.
    • (1992) J Mol Biol , vol.227 , pp. 776-98
    • Tomlinson, I.M.1    Walter, G.2    Marks, J.D.3    Llewelyn, M.B.4    Winter, G.5
  • 59
    • 0030130977 scopus 로고    scopus 로고
    • Non-stochastic utilization of Ig V region genes in unselected human peripheral B cells
    • Huang SC, Jiang R, Glas AM, Milner EC. Non-stochastic utilization of Ig V region genes in unselected human peripheral B cells. Mol Immunol 1996 33 : 553 60.
    • (1996) Mol Immunol , vol.33 , pp. 553-60
    • Huang, S.C.1    Jiang, R.2    Glas, A.M.3    Milner, E.C.4
  • 60
    • 0035384899 scopus 로고    scopus 로고
    • Unequal VH gene rearrangement frequency within the large VH7183 gene family is not due to recombination signal sequence variation, and mapping of the genes shows a bias of rearrangement based on chromosomal location
    • Williams GS, Martinez A, Montalbano A et al. Unequal VH gene rearrangement frequency within the large VH7183 gene family is not due to recombination signal sequence variation, and mapping of the genes shows a bias of rearrangement based on chromosomal location. J Immunol 2001 167 : 257 63.
    • (2001) J Immunol , vol.167 , pp. 257-63
    • Williams, G.S.1    Martinez, A.2    Montalbano, A.3
  • 61
    • 0034854733 scopus 로고    scopus 로고
    • The application of phage display in allergy research: Characterization of IgE, identification of allergens and development of novel therapeutics
    • Edwards MR, Collins AM, Ward RL. The application of phage display in allergy research: characterization of IgE, identification of allergens and development of novel therapeutics. Curr Pharm Biotechnol 2001 2 : 225 40.
    • (2001) Curr Pharm Biotechnol , vol.2 , pp. 225-40
    • Edwards, M.R.1    Collins, A.M.2    Ward, R.L.3
  • 62
    • 0033945481 scopus 로고    scopus 로고
    • Use of phage display technology to investigate allergen-antibody interactions
    • Davies JM, O'Hehir RE, Suphioglu C. Use of phage display technology to investigate allergen-antibody interactions. J Allergy Clin Immunol 2000 105 : 1085 92.
    • (2000) J Allergy Clin Immunol , vol.105 , pp. 1085-92
    • Davies, J.M.1    O'Hehir, R.E.2    Suphioglu, C.3
  • 63
    • 0030456345 scopus 로고    scopus 로고
    • Germinal center formation and local immunoglobulin e (IgE) production in the lung after an airway antigenic challenge
    • Chvatchko Y, Kosco-Vilbois MH, Herren S, Lefort J, Bonnefoy JY. Germinal center formation and local immunoglobulin E (IgE) production in the lung after an airway antigenic challenge. J Exp Med 1996 184 : 2353 60.
    • (1996) J Exp Med , vol.184 , pp. 2353-60
    • Chvatchko, Y.1    Kosco-Vilbois, M.H.2    Herren, S.3    Lefort, J.4    Bonnefoy, J.Y.5
  • 64
    • 0031092642 scopus 로고    scopus 로고
    • Combined diesel exhaust particulate and ragweed allergen challenge markedly enhances human in vivo nasal ragweed-specific IgE and skews cytokine production to a T helper cell 2-type pattern
    • Diaz-Sanchez D, Tsien A, Fleming J, Saxon A. Combined diesel exhaust particulate and ragweed allergen challenge markedly enhances human in vivo nasal ragweed-specific IgE and skews cytokine production to a T helper cell 2-type pattern. J Immunol 1997 158 : 2406 13.
    • (1997) J Immunol , vol.158 , pp. 2406-13
    • Diaz-Sanchez, D.1    Tsien, A.2    Fleming, J.3    Saxon, A.4
  • 65
    • 0031953750 scopus 로고    scopus 로고
    • Expression of IL-4, Cepsilon RNA, and Iepsilon RNA in the nasal mucosa of patients with seasonal rhinitis: Effect of topical corticosteroids
    • Cameron LA, Durham SR, Jacobson MR et al. Expression of IL-4, Cepsilon RNA, and Iepsilon RNA in the nasal mucosa of patients with seasonal rhinitis: effect of topical corticosteroids. J Allergy Clin Immunol 1998 101 : 330 6.
    • (1998) J Allergy Clin Immunol , vol.101 , pp. 330-6
    • Cameron, L.A.1    Durham, S.R.2    Jacobson, M.R.3
  • 66
    • 0034222961 scopus 로고    scopus 로고
    • Local synthesis of epsilon germline gene transcripts, IL-4, and IL-13 in allergic nasal mucosa after ex vivo allergen exposure
    • Cameron L, Hamid Q, Wright E et al. Local synthesis of epsilon germline gene transcripts, IL-4, and IL-13 in allergic nasal mucosa after ex vivo allergen exposure. J Allergy Clin Immunol 2000 106 : 46 52.
    • (2000) J Allergy Clin Immunol , vol.106 , pp. 46-52
    • Cameron, L.1    Hamid, Q.2    Wright, E.3
  • 67
    • 0034744489 scopus 로고    scopus 로고
    • Local expression of epsilon germline gene transcripts and RNA for the epsilon heavy chain of IgE in the bronchial mucosa in atopic and nonatopic asthma
    • Ying S, Humbert M, Meng Q et al. Local expression of epsilon germline gene transcripts and RNA for the epsilon heavy chain of IgE in the bronchial mucosa in atopic and nonatopic asthma. J Allergy Clin Immunol 2001 107 : 686 92.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 686-92
    • Ying, S.1    Humbert, M.2    Meng, Q.3
  • 68
    • 0027297244 scopus 로고
    • Immunolocalization of cytokines in the nasal mucosa of normal and perennial rhinitic subjects. the mast cell as a source of IL-4, IL-5, and IL-6 in human allergic mucosal inflammation
    • Bradding P, Feather IH, Wilson S et al. Immunolocalization of cytokines in the nasal mucosa of normal and perennial rhinitic subjects. The mast cell as a source of IL-4, IL-5, and IL-6 in human allergic mucosal inflammation. J Immunol 1993 151 : 3853 65.
    • (1993) J Immunol , vol.151 , pp. 3853-65
    • Bradding, P.1    Feather, I.H.2    Wilson, S.3
  • 69
    • 0030922389 scopus 로고    scopus 로고
    • Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma
    • Humbert M, Durham SR, Kimmitt P et al. Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma. J Allergy Clin Immunol 1997 99 : 657 65.
    • (1997) J Allergy Clin Immunol , vol.99 , pp. 657-65
    • Humbert, M.1    Durham, S.R.2    Kimmitt, P.3
  • 70
    • 0028863602 scopus 로고
    • Interleukin-13 expression in the nasal mucosa of perennial allergic rhinitis
    • Pawankar RU, Okuda M, Hasegawa S et al. Interleukin-13 expression in the nasal mucosa of perennial allergic rhinitis. Am J Respir Crit Care Med 1995 152 : 2059 67.
    • (1995) Am J Respir Crit Care Med , vol.152 , pp. 2059-67
    • Pawankar, R.U.1    Okuda, M.2    Hasegawa, S.3
  • 71
    • 0031181409 scopus 로고    scopus 로고
    • IL-13 mRNA and immunoreactivity in allergen-induced rhinitis: Comparison with IL-4 expression and modulation by topical glucocorticoid therapy
    • Ghaffar O, Laberge S, Jacobson MR et al. IL-13 mRNA and immunoreactivity in allergen-induced rhinitis: comparison with IL-4 expression and modulation by topical glucocorticoid therapy. Am J Respir Cell Mol Biol 1997 17 : 17 24.
    • (1997) Am J Respir Cell Mol Biol , vol.17 , pp. 17-24
    • Ghaffar, O.1    Laberge, S.2    Jacobson, M.R.3
  • 72
    • 2542565699 scopus 로고    scopus 로고
    • Interleukin-21 is a T-helper cytokine that regulates humoral immunity and cell-mediated anti-tumour responses
    • Sivakumar PV, Foster DC, Clegg CH. Interleukin-21 is a T-helper cytokine that regulates humoral immunity and cell-mediated anti-tumour responses. Immunology 2004 112 : 177 82.
    • (2004) Immunology , vol.112 , pp. 177-82
    • Sivakumar, P.V.1    Foster, D.C.2    Clegg, C.H.3
  • 75
    • 0035664093 scopus 로고    scopus 로고
    • Persistent IgE synthesis in the nasal mucosa of hay fever patients
    • Smurthwaite L, Walker SN, Wilson DR et al. Persistent IgE synthesis in the nasal mucosa of hay fever patients. Eur J Immunol 2001 31 : 3422 31.
    • (2001) Eur J Immunol , vol.31 , pp. 3422-31
    • Smurthwaite, L.1    Walker, S.N.2    Wilson, D.R.3
  • 76
    • 0036142354 scopus 로고    scopus 로고
    • Increases in allergen-specific IgE in BAL after segmental allergen challenge in atopic asthmatics
    • Wilson DR, Merrett TG, Varga EM et al. Increases in allergen-specific IgE in BAL after segmental allergen challenge in atopic asthmatics. Am J Respir Crit Care Med 2002 165 : 22 6.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 22-6
    • Wilson, D.R.1    Merrett, T.G.2    Varga, E.M.3
  • 77
    • 0034114471 scopus 로고    scopus 로고
    • Local production and detection of (specific) IgE in nasal B-cells and plasma cells of allergic rhinitis patients
    • KleinJan A, Vinke JG, Severijnen LW, Fokkens WJ. Local production and detection of (specific) IgE in nasal B-cells and plasma cells of allergic rhinitis patients. Eur Respir J 2000 15 : 491 7.
    • (2000) Eur Respir J , vol.15 , pp. 491-7
    • Kleinjan, A.1    Vinke, J.G.2    Severijnen, L.W.3    Fokkens, W.J.4
  • 78
    • 0030999135 scopus 로고    scopus 로고
    • Nasal mast cells in perennial allergic rhinitics exhibit increased expression of the Fc epsilonRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells
    • Pawankar R, Okuda M, Yssel H, Okumura K, Ra C. Nasal mast cells in perennial allergic rhinitics exhibit increased expression of the Fc epsilonRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells. J Clin Invest 1997 99 : 1492 9.
    • (1997) J Clin Invest , vol.99 , pp. 1492-9
    • Pawankar, R.1    Okuda, M.2    Yssel, H.3    Okumura, K.4    Ra, C.5
  • 79
    • 34249687716 scopus 로고    scopus 로고
    • Mast cells in allergy: Innate instructors of adaptive responses
    • Stelekati E, Orinska Z, Bulfone-Paus S. Mast cells in allergy: innate instructors of adaptive responses. Immunobiology 2007 212 : 505 19.
    • (2007) Immunobiology , vol.212 , pp. 505-19
    • Stelekati, E.1    Orinska, Z.2    Bulfone-Paus, S.3
  • 80
    • 0016684351 scopus 로고
    • Local production of specific IgE antibodies in allergic-rhinitis patients with negative skin tests
    • Huggins KG, Brostoff J. Local production of specific IgE antibodies in allergic-rhinitis patients with negative skin tests. Lancet 1975 306 : 148 50.
    • (1975) Lancet , vol.306 , pp. 148-50
    • Huggins, K.G.1    Brostoff, J.2
  • 81
    • 33750562775 scopus 로고    scopus 로고
    • Local mucosal immunoglobulin e production: Does allergy exist in non-allergic rhinitis?
    • Powe DG, Jones NS. Local mucosal immunoglobulin E production: does allergy exist in non-allergic rhinitis? Clin Exp Allergy 2006 36 : 1367 72.
    • (2006) Clin Exp Allergy , vol.36 , pp. 1367-72
    • Powe, D.G.1    Jones, N.S.2
  • 82
    • 33846239232 scopus 로고    scopus 로고
    • Antigens drive memory IgE responses in human allergy via the nasal mucosa
    • Niederberger V, Ring J, Rakoski J et al. Antigens drive memory IgE responses in human allergy via the nasal mucosa. Int Arch Allergy Immunol 2007 142 : 133 44.
    • (2007) Int Arch Allergy Immunol , vol.142 , pp. 133-44
    • Niederberger, V.1    Ring, J.2    Rakoski, J.3
  • 83
    • 18744414752 scopus 로고    scopus 로고
    • Detection and characterization of plasma cells in peripheral blood: Correlation of IgE+plasma cell frequency with IgE serum titre
    • Horst A, Hunzelmann N, Arce S et al. Detection and characterization of plasma cells in peripheral blood: correlation of IgE+plasma cell frequency with IgE serum titre. Clin Exp Immunol 2002 130 : 370 8.
    • (2002) Clin Exp Immunol , vol.130 , pp. 370-8
    • Horst, A.1    Hunzelmann, N.2    Arce, S.3
  • 84
    • 33846899053 scopus 로고    scopus 로고
    • Antigen-specific immunoglobulin E(+) B cells are preferentially localized within germinal centres
    • Kelly KA, Butch AW. Antigen-specific immunoglobulin E(+) B cells are preferentially localized within germinal centres. Immunology 2006 120 : 345 53.
    • (2006) Immunology , vol.120 , pp. 345-53
    • Kelly, K.A.1    Butch, A.W.2
  • 85
    • 33847273161 scopus 로고    scopus 로고
    • Unique maturation program of the IgE response in vivo
    • Erazo A, Kutchukhidze N, Leung M et al. Unique maturation program of the IgE response in vivo. Immunity 2007 26 : 191 203.
    • (2007) Immunity , vol.26 , pp. 191-203
    • Erazo, A.1    Kutchukhidze, N.2    Leung, M.3
  • 86
    • 14844300188 scopus 로고    scopus 로고
    • The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation
    • Holgate S, Casale T, Wenzel S, Bousquet J, Deniz Y, Reisner C. The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation. J Allergy Clin Immunol 2005 115 : 459 65.
    • (2005) J Allergy Clin Immunol , vol.115 , pp. 459-65
    • Holgate, S.1    Casale, T.2    Wenzel, S.3    Bousquet, J.4    Deniz, Y.5    Reisner, C.6
  • 87
    • 2042448420 scopus 로고    scopus 로고
    • Blocking antibodies in allergen immunotherapy: The Yin and Yang
    • Hardy CL, Rolland JM, O'Hehir RE. Blocking antibodies in allergen immunotherapy: the Yin and Yang. Clin Exp Allergy 2004 34 : 510 2.
    • (2004) Clin Exp Allergy , vol.34 , pp. 510-2
    • Hardy, C.L.1    Rolland, J.M.2    O'Hehir, R.E.3
  • 88
    • 33750336249 scopus 로고    scopus 로고
    • Healthy immune response to allergens: T regulatory cells and more
    • Akdis M. Healthy immune response to allergens: T regulatory cells and more. Curr Opin Immunol 2006 18 : 738 44.
    • (2006) Curr Opin Immunol , vol.18 , pp. 738-44
    • Akdis, M.1


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