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Volumn 8, Issue , 2007, Pages 317-351

11 HPLC method development for drug discovery LC-MS assays in rapid PK applications

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EID: 40649127453     PISSN: 01496395     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0149-6395(07)80017-1     Document Type: Article
Times cited : (3)

References (84)
  • 1
    • 85056517731 scopus 로고    scopus 로고
    • Bioanalytical assays in a drug discovery environment
    • Korfmacher W. (Ed), CRC Press, New York
    • Korfmacher W.A. Bioanalytical assays in a drug discovery environment. In: Korfmacher W. (Ed). Using Mass Spectrometry for Drug Metabolism Studies (2005), CRC Press, New York 1-26
    • (2005) Using Mass Spectrometry for Drug Metabolism Studies , pp. 1-26
    • Korfmacher, W.A.1
  • 2
    • 0042530416 scopus 로고    scopus 로고
    • Lead optimization strategies as part of a drug metabolism environment
    • Korfmacher W.A. Lead optimization strategies as part of a drug metabolism environment. Curr. Opin. Drug Discov. Dev. 6 (2003) 481-485
    • (2003) Curr. Opin. Drug Discov. Dev. , vol.6 , pp. 481-485
    • Korfmacher, W.A.1
  • 3
    • 0030857345 scopus 로고    scopus 로고
    • Pharmacokinetic screening for the selection of new drug discovery candidates is greatly enhanced through the use of liquid chromatography-atmospheric pressure ionization tandem mass spectrometry
    • Bryant M.S., Korfmacher W.A., Wang S., Nardo C., Normeir A.A., and Lin C.C. Pharmacokinetic screening for the selection of new drug discovery candidates is greatly enhanced through the use of liquid chromatography-atmospheric pressure ionization tandem mass spectrometry. J. Chromatogr. A 777 (1997) 61-66
    • (1997) J. Chromatogr. A , vol.777 , pp. 61-66
    • Bryant, M.S.1    Korfmacher, W.A.2    Wang, S.3    Nardo, C.4    Normeir, A.A.5    Lin, C.C.6
  • 4
    • 0034034259 scopus 로고    scopus 로고
    • High-throughput screening in drug metabolism and pharmacokinetic support of drug discovery
    • White R.E. High-throughput screening in drug metabolism and pharmacokinetic support of drug discovery. Annu. Rev. Pharmacol. Toxicol. 40 (2000) 133-157
    • (2000) Annu. Rev. Pharmacol. Toxicol. , vol.40 , pp. 133-157
    • White, R.E.1
  • 5
    • 0035100437 scopus 로고    scopus 로고
    • Cassette-accelerated rapid rat screen: a systematic procedure for the dosing and liquid chromatography/atmospheric pressure ionization tandem mass spectrometric analysis of new chemical entities as part of new drug discovery
    • Korfmacher W.A., Cox K.A., Ng K., Veals J., Hsieh Y., Wainhaus S., Broske L., Prelusky D., Nomeir A., and White R.E. Cassette-accelerated rapid rat screen: a systematic procedure for the dosing and liquid chromatography/atmospheric pressure ionization tandem mass spectrometric analysis of new chemical entities as part of new drug discovery. Rapid Commun. Mass Spectrom. 15 (2001) 335-340
    • (2001) Rapid Commun. Mass Spectrom. , vol.15 , pp. 335-340
    • Korfmacher, W.A.1    Cox, K.A.2    Ng, K.3    Veals, J.4    Hsieh, Y.5    Wainhaus, S.6    Broske, L.7    Prelusky, D.8    Nomeir, A.9    White, R.E.10
  • 6
    • 0036218957 scopus 로고    scopus 로고
    • Rapid determination of pharmacokinetic properties of new chemical entities: in vivo approaches
    • Cox K.A., White R.E., and Korfmacher W.A. Rapid determination of pharmacokinetic properties of new chemical entities: in vivo approaches. Comb. Chem. High Throughput Screen. 5 (2002) 29-37
    • (2002) Comb. Chem. High Throughput Screen. , vol.5 , pp. 29-37
    • Cox, K.A.1    White, R.E.2    Korfmacher, W.A.3
  • 7
    • 26444450077 scopus 로고    scopus 로고
    • Rapid LC/MS/MS method development for drug discovery
    • Xu X., Lan J., and Korfmacher W.A. Rapid LC/MS/MS method development for drug discovery. Anal. Chem. 77 19 (2005) 389A-394A
    • (2005) Anal. Chem. , vol.77 , Issue.19
    • Xu, X.1    Lan, J.2    Korfmacher, W.A.3
  • 8
    • 0020614023 scopus 로고
    • Determination of drugs in blood serum by mass spectrometry/mass spectrometry
    • Brotherton H.O., and Yost R.A. Determination of drugs in blood serum by mass spectrometry/mass spectrometry. Anal. Chem. 55 (1983) 549-553
    • (1983) Anal. Chem. , vol.55 , pp. 549-553
    • Brotherton, H.O.1    Yost, R.A.2
  • 10
    • 0033788742 scopus 로고    scopus 로고
    • AutoScan: an automated workstation for rapid determination of mass and tandem mass spectrometry conditions for quantitative bioanalytical mass spectrometry
    • Whalen K.M., Roger K.J., Cole M.J., and Janiszewski J.S. AutoScan: an automated workstation for rapid determination of mass and tandem mass spectrometry conditions for quantitative bioanalytical mass spectrometry. Rapid Commun. Mass Spectrom. 14 (2000) 2074-2079
    • (2000) Rapid Commun. Mass Spectrom. , vol.14 , pp. 2074-2079
    • Whalen, K.M.1    Roger, K.J.2    Cole, M.J.3    Janiszewski, J.S.4
  • 11
    • 0034778504 scopus 로고    scopus 로고
    • A rapid, automated approach to optimization of multiple reaction monitoring conditions for quantitative bioanalytical mass spectrometry
    • Higton D.M. A rapid, automated approach to optimization of multiple reaction monitoring conditions for quantitative bioanalytical mass spectrometry. Rapid Commun. Mass Spectrom. 15 (2001) 1922-1930
    • (2001) Rapid Commun. Mass Spectrom. , vol.15 , pp. 1922-1930
    • Higton, D.M.1
  • 12
    • 40649085920 scopus 로고    scopus 로고
    • Rapid Pharmacokinetic Screening Using UPLC-MS/MS
    • Somerset, NJ
    • Wainhaus S. Rapid Pharmacokinetic Screening Using UPLC-MS/MS. NJAC-SMS Discussion Group Meeting. Somerset, NJ (2005)
    • (2005) NJAC-SMS Discussion Group Meeting
    • Wainhaus, S.1
  • 13
    • 40649101384 scopus 로고    scopus 로고
    • Evaluating and implementing QuickQuan™ automatic LC-MS/MS method development on ThermoElectron Finnigan TSQ Quantum supporting discovery bioanalytical assays
    • San Antonio, TX, American Society for Mass Spectrometry, New York, NY
    • Caporuscio C., Drexler D., D'Arienzo C., Sleczka B., Cornelius G., Wang J., Sanders M., and Olah T. Evaluating and implementing QuickQuan™ automatic LC-MS/MS method development on ThermoElectron Finnigan TSQ Quantum supporting discovery bioanalytical assays. Proceedings of the 53rd ASMS Conference on Mass Spectrometry and Allied Topics. San Antonio, TX (2005), American Society for Mass Spectrometry, New York, NY
    • (2005) Proceedings of the 53rd ASMS Conference on Mass Spectrometry and Allied Topics
    • Caporuscio, C.1    Drexler, D.2    D'Arienzo, C.3    Sleczka, B.4    Cornelius, G.5    Wang, J.6    Sanders, M.7    Olah, T.8
  • 14
    • 33745125997 scopus 로고    scopus 로고
    • The effect of LC eluent composition on MS responses using electrospray ionization
    • Temesi D., and Law B. The effect of LC eluent composition on MS responses using electrospray ionization. LC-GC 17 (1999) 626-632
    • (1999) LC-GC , vol.17 , pp. 626-632
    • Temesi, D.1    Law, B.2
  • 15
    • 40649084458 scopus 로고    scopus 로고
    • Ultrapressure liquid chromatography
    • Merrimac, WI, University of Wisconsin-Madison, Santa Fe, NM
    • Finch J.W. Ultrapressure liquid chromatography. The 6th Annual Land O'Lakes Bioanalytical Conference. Merrimac, WI (2005), University of Wisconsin-Madison, Santa Fe, NM
    • (2005) The 6th Annual Land O'Lakes Bioanalytical Conference
    • Finch, J.W.1
  • 16
    • 4644265806 scopus 로고    scopus 로고
    • Ultra-performance liquid chromatography coupled to quadrupole-orthogonal time-of-flight mass spectrometry
    • Plumb R., Castro-Perez J., Granger J., Beattie I., Joncour K., and Wright A. Ultra-performance liquid chromatography coupled to quadrupole-orthogonal time-of-flight mass spectrometry. Rapid Commun. Mass Spectrom. 18 (2004) 2331-2337
    • (2004) Rapid Commun. Mass Spectrom. , vol.18 , pp. 2331-2337
    • Plumb, R.1    Castro-Perez, J.2    Granger, J.3    Beattie, I.4    Joncour, K.5    Wright, A.6
  • 17
    • 26444507780 scopus 로고    scopus 로고
    • Improving LC-MS sensitivity through increases in chromatographic performance: comparison of UPLC-ES/MS/MS to HPLC-ES/MS/MS
    • Churchwell M.I., Twaddle N.C., Meeker L.R., and Doerge D.R. Improving LC-MS sensitivity through increases in chromatographic performance: comparison of UPLC-ES/MS/MS to HPLC-ES/MS/MS. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 825 (2005) 134-143
    • (2005) J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. , vol.825 , pp. 134-143
    • Churchwell, M.I.1    Twaddle, N.C.2    Meeker, L.R.3    Doerge, D.R.4
  • 18
    • 40649096238 scopus 로고    scopus 로고
    • A novel approach for the quantification and identification of diuretics by LC/MS/MS and LC/TOF
    • Nashville, TN, American Society for Mass Spectrometry, Madison, WI
    • Swartz M.Z., Granger J.H., and Plumb R.S. A novel approach for the quantification and identification of diuretics by LC/MS/MS and LC/TOF. Proceedings of the 52nd ASMS Conference on Mass Spectrometry and Allied Topics. Nashville, TN (2004), American Society for Mass Spectrometry, Madison, WI
    • (2004) Proceedings of the 52nd ASMS Conference on Mass Spectrometry and Allied Topics
    • Swartz, M.Z.1    Granger, J.H.2    Plumb, R.S.3
  • 21
    • 1642298855 scopus 로고    scopus 로고
    • Simultaneous quantification of cyclophosphamide, 4-hydroxycyclophosphamide, N,N′,N″-triethylenethiophosphoramide (thiotepa) and N,N′,N″-triethylenephosphoramide (tepa) in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry
    • de Jonge M.E., van Dam S.M., Hillebrand M.J., Rosing H., Huitema A.D., Rodenhuis S., and Beijnen J.H. Simultaneous quantification of cyclophosphamide, 4-hydroxycyclophosphamide, N,N′,N″-triethylenethiophosphoramide (thiotepa) and N,N′,N″-triethylenephosphoramide (tepa) in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. J. Mass Spectrom. 39 (2004) 262-271
    • (2004) J. Mass Spectrom. , vol.39 , pp. 262-271
    • de Jonge, M.E.1    van Dam, S.M.2    Hillebrand, M.J.3    Rosing, H.4    Huitema, A.D.5    Rodenhuis, S.6    Beijnen, J.H.7
  • 22
    • 1842787877 scopus 로고    scopus 로고
    • Simultaneous quantification of the new HIV protease inhibitors atazanavir and tipranavir in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry
    • Crommentuyn K.M., Rosing H., Hillebrand M.J., Huitema A.D., and Beijnen J.H. Simultaneous quantification of the new HIV protease inhibitors atazanavir and tipranavir in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 804 (2004) 359-367
    • (2004) J. Chromatogr. B Anal. Technol. Biomed. Life Sci. , vol.804 , pp. 359-367
    • Crommentuyn, K.M.1    Rosing, H.2    Hillebrand, M.J.3    Huitema, A.D.4    Beijnen, J.H.5
  • 23
    • 0019767942 scopus 로고
    • Evaluation of the relative efficacy of various techniques for deproteinizing plasma samples prior to high-performance liquid chromatographic analysis
    • Blanchard J. Evaluation of the relative efficacy of various techniques for deproteinizing plasma samples prior to high-performance liquid chromatographic analysis. J. Chromatogr. 226 (1981) 455-460
    • (1981) J. Chromatogr. , vol.226 , pp. 455-460
    • Blanchard, J.1
  • 24
    • 23044464523 scopus 로고    scopus 로고
    • Development of a low volume plasma sample procedure for LC-MS/MS assays used for drug discovery applications
    • Xu X., Zhou Q., and Korfmacher W. Development of a low volume plasma sample procedure for LC-MS/MS assays used for drug discovery applications. Rapid Commun. Mass Spectrom. 19 (2005) 2131-2136
    • (2005) Rapid Commun. Mass Spectrom. , vol.19 , pp. 2131-2136
    • Xu, X.1    Zhou, Q.2    Korfmacher, W.3
  • 25
    • 0036001218 scopus 로고    scopus 로고
    • Determination of drug concentrations in plasma by a highly automated, generic and flexible protein precipitation and liquid chromatography/tandem mass spectrometry method applicable to the drug discovery environment
    • O'Connor D., Clarke D.E., Morrison D., and Watt A.P. Determination of drug concentrations in plasma by a highly automated, generic and flexible protein precipitation and liquid chromatography/tandem mass spectrometry method applicable to the drug discovery environment. Rapid Commun. Mass Spectrom. 16 (2002) 1065-1071
    • (2002) Rapid Commun. Mass Spectrom. , vol.16 , pp. 1065-1071
    • O'Connor, D.1    Clarke, D.E.2    Morrison, D.3    Watt, A.P.4
  • 26
    • 0344665701 scopus 로고    scopus 로고
    • Validation and application of a liquid chromatography-tandem mass spectrometric method for the determination of SCH 211803 in rat and monkey plasma using automated 96-well protein precipitation
    • Yang L., Wu N., Clement R.P., and Rudewicz P.J. Validation and application of a liquid chromatography-tandem mass spectrometric method for the determination of SCH 211803 in rat and monkey plasma using automated 96-well protein precipitation. J. Chromatogr. B 799 (2004) 271-280
    • (2004) J. Chromatogr. B , vol.799 , pp. 271-280
    • Yang, L.1    Wu, N.2    Clement, R.P.3    Rudewicz, P.J.4
  • 27
    • 0033962676 scopus 로고    scopus 로고
    • Semi-automated 96-well liquid-liquid extraction for quantitation of drugs in biological fluids
    • Zhang N., Hoffman K.L., Li W., and Rossi D.T. Semi-automated 96-well liquid-liquid extraction for quantitation of drugs in biological fluids. J. Pharm. Biomed. Anal. 22 (2000) 131-138
    • (2000) J. Pharm. Biomed. Anal. , vol.22 , pp. 131-138
    • Zhang, N.1    Hoffman, K.L.2    Li, W.3    Rossi, D.T.4
  • 28
    • 0033168125 scopus 로고    scopus 로고
    • Liquid-liquid extraction in the 96-well plate format with SRM LC/MS quantitative determination of methotrexate and its major metabolite in human plasma
    • Steinborner S., and Henion J. Liquid-liquid extraction in the 96-well plate format with SRM LC/MS quantitative determination of methotrexate and its major metabolite in human plasma. Anal. Chem. 71 (1999) 2340-2345
    • (1999) Anal. Chem. , vol.71 , pp. 2340-2345
    • Steinborner, S.1    Henion, J.2
  • 29
    • 0034074783 scopus 로고    scopus 로고
    • Liquid-liquid extraction using 96-well plate format in conjunction with liquid chromatography/tandem mass spectrometry for quantitative determination of methylphenidate (Ritalin) in human plasma
    • Ramos L., Bakhtiar R., and Tse F.S.L. Liquid-liquid extraction using 96-well plate format in conjunction with liquid chromatography/tandem mass spectrometry for quantitative determination of methylphenidate (Ritalin) in human plasma. Rapid Commun. Mass Spectrom. 14 (2000) 740-745
    • (2000) Rapid Commun. Mass Spectrom. , vol.14 , pp. 740-745
    • Ramos, L.1    Bakhtiar, R.2    Tse, F.S.L.3
  • 30
    • 17144413342 scopus 로고    scopus 로고
    • Fully automated liquid-liquid extraction for the determination of a novel insulin sensitizer in human plasma by heated nebulizer and turbo ionspray liquid chromatography-tandem mass spectrometry
    • Riffel K.A., Groff M.A., Wenning L., Song H., and Lo M.W. Fully automated liquid-liquid extraction for the determination of a novel insulin sensitizer in human plasma by heated nebulizer and turbo ionspray liquid chromatography-tandem mass spectrometry. J. Chromatogr. B 819 (2005) 293-300
    • (2005) J. Chromatogr. B , vol.819 , pp. 293-300
    • Riffel, K.A.1    Groff, M.A.2    Wenning, L.3    Song, H.4    Lo, M.W.5
  • 31
    • 1642452675 scopus 로고    scopus 로고
    • Quantitative analysis of simvastatin and its beta-hydroxy acid in human plasma using automated liquid-liquid extraction based on 96-well plate format and liquid chromatography-tandem mass spectrometry
    • Zhang N., Yang A., Rogers J.D., and Zhao J.J. Quantitative analysis of simvastatin and its beta-hydroxy acid in human plasma using automated liquid-liquid extraction based on 96-well plate format and liquid chromatography-tandem mass spectrometry. J. Pharm. Biomed. Anal. 34 (2004) 175-187
    • (2004) J. Pharm. Biomed. Anal. , vol.34 , pp. 175-187
    • Zhang, N.1    Yang, A.2    Rogers, J.D.3    Zhao, J.J.4
  • 32
    • 0028302364 scopus 로고
    • Solid-phase extraction technique for the analysis of biological samples
    • Krishnan T.R., and Ibraham I. Solid-phase extraction technique for the analysis of biological samples. J. Pharm. Biomed. Anal. 12 (1994) 287-294
    • (1994) J. Pharm. Biomed. Anal. , vol.12 , pp. 287-294
    • Krishnan, T.R.1    Ibraham, I.2
  • 33
    • 0030582628 scopus 로고    scopus 로고
    • Use of reduced sorbent bed and disk membrane solid-phase extraction for the analysis of pharmaceutical compounds in biological fluids, with applications in the 96-well format
    • Plumb R.S., Gray R.D., Harker A.J., and Taylor S.J. Use of reduced sorbent bed and disk membrane solid-phase extraction for the analysis of pharmaceutical compounds in biological fluids, with applications in the 96-well format. J. Chromatogr. B 687 (1996) 457-461
    • (1996) J. Chromatogr. B , vol.687 , pp. 457-461
    • Plumb, R.S.1    Gray, R.D.2    Harker, A.J.3    Taylor, S.J.4
  • 34
    • 0031975107 scopus 로고    scopus 로고
    • High throughput liquid chromatography/mass spectrometry bioanalysis using 96-well disk solid-phase extraction plate for the sample preparation
    • Simpson H., Berthemy A., Buhrman D., Burton R., Newton J., Kealy M., Wells D., and Wu D. High throughput liquid chromatography/mass spectrometry bioanalysis using 96-well disk solid-phase extraction plate for the sample preparation. Rapid Commun. Mass Spectrom. 12 (1998) 75-82
    • (1998) Rapid Commun. Mass Spectrom. , vol.12 , pp. 75-82
    • Simpson, H.1    Berthemy, A.2    Buhrman, D.3    Burton, R.4    Newton, J.5    Kealy, M.6    Wells, D.7    Wu, D.8
  • 36
    • 0033047741 scopus 로고    scopus 로고
    • Fully automated analytical method for codeine quantification in human plasma using on-line solid-phase extraction and high-performance liquid chromatography with ultraviolet detection
    • Pascual J.A., and Sanagustin J. Fully automated analytical method for codeine quantification in human plasma using on-line solid-phase extraction and high-performance liquid chromatography with ultraviolet detection. J. Chromatogr. 724 (1999) 295-302
    • (1999) J. Chromatogr. , vol.724 , pp. 295-302
    • Pascual, J.A.1    Sanagustin, J.2
  • 37
    • 0031685139 scopus 로고    scopus 로고
    • The use of high-flow high performance liquid chromatography coupled with positive and negative ion electrospray tandem mass spectrometry for quantitative bioanalysis via direct injection of the plasma/serum samples
    • Jemal M., Xia Y.Q., and Whigan D.B. The use of high-flow high performance liquid chromatography coupled with positive and negative ion electrospray tandem mass spectrometry for quantitative bioanalysis via direct injection of the plasma/serum samples. Rapid Commun. Mass Spectrom. 12 (1998) 1389-1399
    • (1998) Rapid Commun. Mass Spectrom. , vol.12 , pp. 1389-1399
    • Jemal, M.1    Xia, Y.Q.2    Whigan, D.B.3
  • 38
    • 0036498075 scopus 로고    scopus 로고
    • The investigation and the use of high flow column-switching LC/MS/MS as a high-throughput approach for direct plasma sample analysis of single and multiple components in pharmacokinetic studies
    • Zeng H., Wu J.T., and Unger S.E. The investigation and the use of high flow column-switching LC/MS/MS as a high-throughput approach for direct plasma sample analysis of single and multiple components in pharmacokinetic studies. J. Pharm. Biomed. Anal. 27 (2002) 967-982
    • (2002) J. Pharm. Biomed. Anal. , vol.27 , pp. 967-982
    • Zeng, H.1    Wu, J.T.2    Unger, S.E.3
  • 39
    • 0033964293 scopus 로고    scopus 로고
    • Ternary-column system for high-throughput direct-injection bioanalysis by liquid chromatography/tandem mass spectrometry
    • Xia Y.Q., Whigan D.B., Powell M.L., and Jamal M. Ternary-column system for high-throughput direct-injection bioanalysis by liquid chromatography/tandem mass spectrometry. Rapid Commun. Mass Spectrom. 14 (2000) 105-111
    • (2000) Rapid Commun. Mass Spectrom. , vol.14 , pp. 105-111
    • Xia, Y.Q.1    Whigan, D.B.2    Powell, M.L.3    Jamal, M.4
  • 40
    • 85153991893 scopus 로고    scopus 로고
    • Ayrton, J., Dear, G. J., Leavens, W. J., Mallett, D. N., and Plumb, R. S. (197). The use of turbulent flow chromatography/mass spectrometry for the rapid, direct analysis of a novel pharmaceutical compound in plasma. Rapid Commun. Mass Spectrom. 11, 1953-1958.
    • Ayrton, J., Dear, G. J., Leavens, W. J., Mallett, D. N., and Plumb, R. S. (197). The use of turbulent flow chromatography/mass spectrometry for the rapid, direct analysis of a novel pharmaceutical compound in plasma. Rapid Commun. Mass Spectrom. 11, 1953-1958.
  • 41
    • 0037446554 scopus 로고    scopus 로고
    • Direct plasma analysis of drug compounds using monolithic column liquid chromatography and tandem mass spectrometry
    • Hsieh Y., Wang G., Wang Y., Chackalamannil S., and Korfmacher W.A. Direct plasma analysis of drug compounds using monolithic column liquid chromatography and tandem mass spectrometry. Anal. Chem. 75 (2003) 1812-1818
    • (2003) Anal. Chem. , vol.75 , pp. 1812-1818
    • Hsieh, Y.1    Wang, G.2    Wang, Y.3    Chackalamannil, S.4    Korfmacher, W.A.5
  • 43
    • 1842594494 scopus 로고    scopus 로고
    • Monolithic columns for liquid chromatography
    • Tanaka N., and Kobayashi H. Monolithic columns for liquid chromatography. Anal. Bioanal. Chem. 376 (2003) 298-301
    • (2003) Anal. Bioanal. Chem. , vol.376 , pp. 298-301
    • Tanaka, N.1    Kobayashi, H.2
  • 44
    • 0033861328 scopus 로고    scopus 로고
    • Direct analysis of plasma samples for drug discovery compounds using mixed-function column liquid chromatography tandem mass spectrometry
    • Hsieh Y., Bryant M.S., Gruela G., Brisson J.M., and Korfmacher W.A. Direct analysis of plasma samples for drug discovery compounds using mixed-function column liquid chromatography tandem mass spectrometry. Rapid Commun. Mass Spectrom. 14 (2000) 1384-1390
    • (2000) Rapid Commun. Mass Spectrom. , vol.14 , pp. 1384-1390
    • Hsieh, Y.1    Bryant, M.S.2    Gruela, G.3    Brisson, J.M.4    Korfmacher, W.A.5
  • 45
    • 0035879905 scopus 로고    scopus 로고
    • Direct analysis of urinary trans,trans-muconic acid by coupled column liquid chromatography and spectrophotometric ultraviolet detection: method applicability to human urine
    • Marrubini G., Coccini T., and Manzo L. Direct analysis of urinary trans,trans-muconic acid by coupled column liquid chromatography and spectrophotometric ultraviolet detection: method applicability to human urine. J. Chromatogr. B Biomed. Sci. Appl. 758 (2001) 295-303
    • (2001) J. Chromatogr. B Biomed. Sci. Appl. , vol.758 , pp. 295-303
    • Marrubini, G.1    Coccini, T.2    Manzo, L.3
  • 46
    • 0032851625 scopus 로고    scopus 로고
    • Semi-permeable surface analytical reversed-phase column for the improved trace analysis of acidic pesticides in water with coupled-column reversed-phase liquid chromatography with UV detection. Determination of bromoxynil and bentazone in surface water
    • Hogendoorn E.A., Westhuis K., Dijkman E., Heusinkveld H.A., den Boer A.C., Evers E.A., and Baumann R.A. Semi-permeable surface analytical reversed-phase column for the improved trace analysis of acidic pesticides in water with coupled-column reversed-phase liquid chromatography with UV detection. Determination of bromoxynil and bentazone in surface water. J. Chromatogr. A 858 (1999) 45-54
    • (1999) J. Chromatogr. A , vol.858 , pp. 45-54
    • Hogendoorn, E.A.1    Westhuis, K.2    Dijkman, E.3    Heusinkveld, H.A.4    den Boer, A.C.5    Evers, E.A.6    Baumann, R.A.7
  • 47
    • 75249102235 scopus 로고    scopus 로고
    • Matrix effects: causes and solutions
    • Korfmacher W. (Ed), CRC Press, New York, NY
    • Mei H. Matrix effects: causes and solutions. In: Korfmacher W. (Ed). Using Mass Spectrometry for Drug Metabolism Studies (2005), CRC Press, New York, NY 103-150
    • (2005) Using Mass Spectrometry for Drug Metabolism Studies , pp. 103-150
    • Mei, H.1
  • 49
    • 0033404430 scopus 로고    scopus 로고
    • Effects of salt concentration on analyte response using electrospray ionization mass spectrometry
    • Constantopoulos T.L., Jackson G.S., and Enke C.G. Effects of salt concentration on analyte response using electrospray ionization mass spectrometry. J. Am. Soc. Mass Spectrom. 10 (1999) 625-634
    • (1999) J. Am. Soc. Mass Spectrom. , vol.10 , pp. 625-634
    • Constantopoulos, T.L.1    Jackson, G.S.2    Enke, C.G.3
  • 51
    • 0037214121 scopus 로고    scopus 로고
    • Investigation of matrix effects in bioanalytical high-performance liquid chromatography/tandem mass spectrometric assays: application to drug discovery
    • Mei H., Hsieh Y., Nardo C., Xu X., Wang S., Ng K., and Korfmacher W.A. Investigation of matrix effects in bioanalytical high-performance liquid chromatography/tandem mass spectrometric assays: application to drug discovery. Rapid Commun. Mass Spectrom. 17 (2003) 97-103
    • (2003) Rapid Commun. Mass Spectrom. , vol.17 , pp. 97-103
    • Mei, H.1    Hsieh, Y.2    Nardo, C.3    Xu, X.4    Wang, S.5    Ng, K.6    Korfmacher, W.A.7
  • 52
    • 25144469720 scopus 로고    scopus 로고
    • A study of common discovery dosing formulation components and their potential for causing time-dependent matrix effects in high-performance liquid chromatography tandem mass spectrometry assays
    • Xu X., Mei H., Wang S., Zhou Q., Wang G., Broske L., Pena A., and Korfmacher W.A. A study of common discovery dosing formulation components and their potential for causing time-dependent matrix effects in high-performance liquid chromatography tandem mass spectrometry assays. Rapid Commun. Mass Spectrom. 19 (2005) 2643-2650
    • (2005) Rapid Commun. Mass Spectrom. , vol.19 , pp. 2643-2650
    • Xu, X.1    Mei, H.2    Wang, S.3    Zhou, Q.4    Wang, G.5    Broske, L.6    Pena, A.7    Korfmacher, W.A.8
  • 53
    • 0034461768 scopus 로고    scopus 로고
    • Drug-like properties and the causes of poor solubility and poor permeability
    • Lipinski C. Drug-like properties and the causes of poor solubility and poor permeability. J. Pharmacol. Toxicol. Methods 44 (2000) 235-249
    • (2000) J. Pharmacol. Toxicol. Methods , vol.44 , pp. 235-249
    • Lipinski, C.1
  • 54
    • 40649095122 scopus 로고    scopus 로고
    • Characterisation of serum albumin and LysoPCs as major contributors to plasma sample matrix effects on electrospray ionisation efficiency
    • Montreal, Canada, American Society for Mass Spectrometry, Boca Raton, FL
    • Ahnoff M., Wurzer A., Lindmark B., and Jussila R. Characterisation of serum albumin and LysoPCs as major contributors to plasma sample matrix effects on electrospray ionisation efficiency. Proceedings of the 51st ASMS Conference on Mass Spectrometry and Allied Topics. Montreal, Canada (2003), American Society for Mass Spectrometry, Boca Raton, FL
    • (2003) Proceedings of the 51st ASMS Conference on Mass Spectrometry and Allied Topics
    • Ahnoff, M.1    Wurzer, A.2    Lindmark, B.3    Jussila, R.4
  • 55
    • 0035847160 scopus 로고    scopus 로고
    • Effect of liquid chromatography separation of complex matrices on liquid chromatography-tandem mass spectrometry signal suppression
    • Choi B.K., Hercules D.M., and Gusev A.I. Effect of liquid chromatography separation of complex matrices on liquid chromatography-tandem mass spectrometry signal suppression. J. Chromatogr. A 907 (2001) 337-342
    • (2001) J. Chromatogr. A , vol.907 , pp. 337-342
    • Choi, B.K.1    Hercules, D.M.2    Gusev, A.I.3
  • 56
    • 0034930266 scopus 로고    scopus 로고
    • LC-MS/MS signal suppression effects in the analysis of pesticides in complex environmental matrices
    • Choi B.K., Hercules D.M., and Gusev A.I. LC-MS/MS signal suppression effects in the analysis of pesticides in complex environmental matrices. Fresenius J. Anal. Chem. 369 (2001) 370-377
    • (2001) Fresenius J. Anal. Chem. , vol.369 , pp. 370-377
    • Choi, B.K.1    Hercules, D.M.2    Gusev, A.I.3
  • 57
    • 0035894197 scopus 로고    scopus 로고
    • Reduction in matrix-related signal suppression effects in electrospray ionization mass spectrometry using on-line two-dimensional liquid chromatography
    • Pascoe R., Foley J.P., and Gusev A.I. Reduction in matrix-related signal suppression effects in electrospray ionization mass spectrometry using on-line two-dimensional liquid chromatography. Anal. Chem. 73 (2001) 6014-6023
    • (2001) Anal. Chem. , vol.73 , pp. 6014-6023
    • Pascoe, R.1    Foley, J.P.2    Gusev, A.I.3
  • 58
    • 0032011562 scopus 로고    scopus 로고
    • Matrix effect in quantitative LC/MS/MS analyses of biological fluids: a method for determination of finasteride in human plasma at picogram per milliliter concentrations
    • Matuszewski B.K., Constanzer M.L., and Chevez-Eng C.M. Matrix effect in quantitative LC/MS/MS analyses of biological fluids: a method for determination of finasteride in human plasma at picogram per milliliter concentrations. Anal. Chem. 70 (1998) 882-889
    • (1998) Anal. Chem. , vol.70 , pp. 882-889
    • Matuszewski, B.K.1    Constanzer, M.L.2    Chevez-Eng, C.M.3
  • 59
    • 0032186343 scopus 로고
    • Sample preparation for LC/MS/MS: analyzing biological and environmental samples
    • Henion J., Brewer E., and Rule G. Sample preparation for LC/MS/MS: analyzing biological and environmental samples. Anal. Chem. 70 (1988) 650A-656A
    • (1988) Anal. Chem. , vol.70
    • Henion, J.1    Brewer, E.2    Rule, G.3
  • 60
    • 0037115384 scopus 로고    scopus 로고
    • Effect of signal interference from dosing excipients on pharmacokinetic screening of drug candidates by liquid chromatography/mass spectrometry
    • Tong X.S., Wang J., Zheng S., Pivnichny J.V., Griffin P.R., Shen X., Donnelly M., Vakerich K., Nunes C., and Fenyk-Melody J. Effect of signal interference from dosing excipients on pharmacokinetic screening of drug candidates by liquid chromatography/mass spectrometry. Anal. Chem. 74 (2002) 6305-6313
    • (2002) Anal. Chem. , vol.74 , pp. 6305-6313
    • Tong, X.S.1    Wang, J.2    Zheng, S.3    Pivnichny, J.V.4    Griffin, P.R.5    Shen, X.6    Donnelly, M.7    Vakerich, K.8    Nunes, C.9    Fenyk-Melody, J.10
  • 61
    • 0037234906 scopus 로고    scopus 로고
    • Post-column infusion study of the 'dosing vehicle effect' in the liquid chromatography/tandem mass spectrometric analysis of discovery pharmacokinetic samples
    • Shou W.Z., and Naidong W. Post-column infusion study of the 'dosing vehicle effect' in the liquid chromatography/tandem mass spectrometric analysis of discovery pharmacokinetic samples. Rapid Commun. Mass Spectrom. 17 (2003) 589-597
    • (2003) Rapid Commun. Mass Spectrom. , vol.17 , pp. 589-597
    • Shou, W.Z.1    Naidong, W.2
  • 62
    • 40649128211 scopus 로고    scopus 로고
    • Investigation of ion-suppression from a formulation agent in quantitative LC-MS/MS bioanalysis: a case study on Tween 80
    • Montreal, Canada, American Society for Mass Spectrometry, Santa Fe, NM
    • Larger P.J., Breda M., James C.A., Hughes H.J., and Pisano R. Investigation of ion-suppression from a formulation agent in quantitative LC-MS/MS bioanalysis: a case study on Tween 80. Proceedings of the 51st ASMS Conference on Mass Spectrometry and Allied Topics. Montreal, Canada (2003), American Society for Mass Spectrometry, Santa Fe, NM
    • (2003) Proceedings of the 51st ASMS Conference on Mass Spectrometry and Allied Topics
    • Larger, P.J.1    Breda, M.2    James, C.A.3    Hughes, H.J.4    Pisano, R.5
  • 63
    • 0035543080 scopus 로고    scopus 로고
    • Quantitative screening and matrix effect studies of drug discovery compounds in monkey plasma using fast-gradient liquid chromatography/tandem mass spectrometry
    • Hsieh Y., Chintala M., Mei H., Agans J., Brisson J.M., Ng K., and Korfmacher W.A. Quantitative screening and matrix effect studies of drug discovery compounds in monkey plasma using fast-gradient liquid chromatography/tandem mass spectrometry. Rapid Commun. Mass Spectrom. 15 (2001) 2481-2487
    • (2001) Rapid Commun. Mass Spectrom. , vol.15 , pp. 2481-2487
    • Hsieh, Y.1    Chintala, M.2    Mei, H.3    Agans, J.4    Brisson, J.M.5    Ng, K.6    Korfmacher, W.A.7
  • 64
    • 0037663202 scopus 로고    scopus 로고
    • Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS
    • Matuszewski B.K., Constanzer M.L., and Chavez-Eng C.M. Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS. Anal. Chem. 75 (2003) 3019-3030
    • (2003) Anal. Chem. , vol.75 , pp. 3019-3030
    • Matuszewski, B.K.1    Constanzer, M.L.2    Chavez-Eng, C.M.3
  • 65
    • 0032986050 scopus 로고    scopus 로고
    • The effects of sample preparation methods on the variability of the electrospray ionization response for model drug compounds
    • Bonfiglio R., King R.C., Olah T.V., and Merkle K. The effects of sample preparation methods on the variability of the electrospray ionization response for model drug compounds. Rapid Commun. Mass Spectrom. 13 (1999) 1175-1185
    • (1999) Rapid Commun. Mass Spectrom. , vol.13 , pp. 1175-1185
    • Bonfiglio, R.1    King, R.C.2    Olah, T.V.3    Merkle, K.4
  • 67
    • 0037059579 scopus 로고    scopus 로고
    • Matrix effect and correction by standard addition in quantitative liquid chromatographic-mass spectrometric analysis of diarrhetic shellfish poisoning toxins
    • Ito S., and Tsukada K. Matrix effect and correction by standard addition in quantitative liquid chromatographic-mass spectrometric analysis of diarrhetic shellfish poisoning toxins. J. Chromatogr. A 943 (2002) 39-46
    • (2002) J. Chromatogr. A , vol.943 , pp. 39-46
    • Ito, S.1    Tsukada, K.2
  • 68
    • 0034654478 scopus 로고    scopus 로고
    • Liquid chromatography/mass spectrometry methods for distinguishing N-oxides from hydroxylated compounds
    • Ramanathan R., Su A.D., Alvarez N., Blumenkrantz N., Chowdhury S.K., Alton K., and Patrick J. Liquid chromatography/mass spectrometry methods for distinguishing N-oxides from hydroxylated compounds. Anal. Chem. 72 (2000) 1352-1359
    • (2000) Anal. Chem. , vol.72 , pp. 1352-1359
    • Ramanathan, R.1    Su, A.D.2    Alvarez, N.3    Blumenkrantz, N.4    Chowdhury, S.K.5    Alton, K.6    Patrick, J.7
  • 69
    • 0032896493 scopus 로고    scopus 로고
    • The need for adequate chromatographic separation in the quantitative determination of drugs in biological samples by high performance liquid chromatography with tandem mass spectrometry
    • Jemal M., and Xia Y.Q. The need for adequate chromatographic separation in the quantitative determination of drugs in biological samples by high performance liquid chromatography with tandem mass spectrometry. Rapid Commun. Mass Spectrom. 13 (1999) 97
    • (1999) Rapid Commun. Mass Spectrom. , vol.13 , pp. 97
    • Jemal, M.1    Xia, Y.Q.2
  • 70
    • 0034283830 scopus 로고    scopus 로고
    • Development and validation of a sensitive method for hydromorphone in human plasma by normal phase liquid chromatography-tandem mass spectrometry
    • Weng N., Naidong W., Jiang X., Newland K., Coe R., Lin P., and Lee J. Development and validation of a sensitive method for hydromorphone in human plasma by normal phase liquid chromatography-tandem mass spectrometry. J. Pharm. Biomed. Anal. 23 (2000) 697-704
    • (2000) J. Pharm. Biomed. Anal. , vol.23 , pp. 697-704
    • Weng, N.1    Naidong, W.2    Jiang, X.3    Newland, K.4    Coe, R.5    Lin, P.6    Lee, J.7
  • 71
    • 0033794790 scopus 로고    scopus 로고
    • The need for chromatographic and mass resolution in liquid chromatography/tandem mass spectrometric methods used for quantitation of lactones and corresponding hydroxy acids in biological samples
    • Jemal M., and Ouyang Z. The need for chromatographic and mass resolution in liquid chromatography/tandem mass spectrometric methods used for quantitation of lactones and corresponding hydroxy acids in biological samples. Rapid Commun. Mass Spectrom. 14 (2000) 1757-1765
    • (2000) Rapid Commun. Mass Spectrom. , vol.14 , pp. 1757-1765
    • Jemal, M.1    Ouyang, Z.2
  • 72
    • 0033827448 scopus 로고    scopus 로고
    • Bioanalytical applications of 'fast chromatography' to high-throughput liquid chromatography/tandem mass spectrometric quantitation
    • Romanyshyn L., Tiller P.R., and Hop C.E.C.A. Bioanalytical applications of 'fast chromatography' to high-throughput liquid chromatography/tandem mass spectrometric quantitation. Rapid Commun. Mass Spectrom. 14 (2000) 1662-1668
    • (2000) Rapid Commun. Mass Spectrom. , vol.14 , pp. 1662-1668
    • Romanyshyn, L.1    Tiller, P.R.2    Hop, C.E.C.A.3
  • 73
    • 40649083413 scopus 로고    scopus 로고
    • A mass spectrometry primer
    • Rossi D.T., and Sinz M.W. (Eds), Marcel Dekker, Santa Fe, NM
    • Fountain S.T. A mass spectrometry primer. In: Rossi D.T., and Sinz M.W. (Eds). Mass Spectrometry in Drug Discovery (2002), Marcel Dekker, Santa Fe, NM 25-84
    • (2002) Mass Spectrometry in Drug Discovery , pp. 25-84
    • Fountain, S.T.1
  • 74
    • 85056511400 scopus 로고    scopus 로고
    • Using higher mass resolution in quantitative assays
    • Korfmacher W. (Ed), CRC Press, New York, NY
    • Xu X. Using higher mass resolution in quantitative assays. In: Korfmacher W. (Ed). Using Mass Spectrometry for Drug Metabolism Studies (2005), CRC Press, New York, NY 203-228
    • (2005) Using Mass Spectrometry for Drug Metabolism Studies , pp. 203-228
    • Xu, X.1
  • 75
    • 0037260829 scopus 로고    scopus 로고
    • Comparison of conventional and enhanced mass resolution triple-quadrupole mass spectrometers for discovery bioanalytical applications
    • Xu X., Veals J., and Korfmacher W.A. Comparison of conventional and enhanced mass resolution triple-quadrupole mass spectrometers for discovery bioanalytical applications. Rapid Commun. Mass Spectrom. 17 (2003) 832-837
    • (2003) Rapid Commun. Mass Spectrom. , vol.17 , pp. 832-837
    • Xu, X.1    Veals, J.2    Korfmacher, W.A.3
  • 76
    • 0037216382 scopus 로고    scopus 로고
    • Enhanced resolution triple-quadrupole mass spectrometry for fast quantitative bioanalysis using liquid chromatography/tandem mass spectrometry: investigations of parameters that affect ruggedness
    • Jemal M., and Ouyang Z. Enhanced resolution triple-quadrupole mass spectrometry for fast quantitative bioanalysis using liquid chromatography/tandem mass spectrometry: investigations of parameters that affect ruggedness. Rapid Commun. Mass Spectrom. 17 (2003) 24-38
    • (2003) Rapid Commun. Mass Spectrom. , vol.17 , pp. 24-38
    • Jemal, M.1    Ouyang, Z.2
  • 77
    • 0037216382 scopus 로고    scopus 로고
    • Enhanced resolution triple-quadrupole mass spectrometry for fast quantitative bioanalysis using liquid chromatography/tandem mass spectrometry: investigations of parameters that affect ruggedness
    • Jemal M., and Ouyang Z. Enhanced resolution triple-quadrupole mass spectrometry for fast quantitative bioanalysis using liquid chromatography/tandem mass spectrometry: investigations of parameters that affect ruggedness. Rapid Commun. Mass Spectrom. 17 (2003) 24-38
    • (2003) Rapid Commun. Mass Spectrom. , vol.17 , pp. 24-38
    • Jemal, M.1    Ouyang, Z.2
  • 79
    • 0036032589 scopus 로고    scopus 로고
    • Investigation of an enhanced resolution triple quadrupole mass spectrometer for high-throughput liquid chromatography/tandem mass spectrometry assays
    • Yang L., Amad M., Winnik W.M., Schoen A.E., Schweingruber H., Mylchreest I., and Rudewicz P.J. Investigation of an enhanced resolution triple quadrupole mass spectrometer for high-throughput liquid chromatography/tandem mass spectrometry assays. Rapid Commun. Mass Spectrom. 16 (2002) 2060-2066
    • (2002) Rapid Commun. Mass Spectrom. , vol.16 , pp. 2060-2066
    • Yang, L.1    Amad, M.2    Winnik, W.M.3    Schoen, A.E.4    Schweingruber, H.5    Mylchreest, I.6    Rudewicz, P.J.7
  • 81
    • 40649091252 scopus 로고    scopus 로고
    • Determination of alprazolam in the presence of polypropylene glycol utilizing the high resolution capability of a triple quadrupole mass spectrometer
    • Chicago, IL, American Society for Mass Spectrometry, Santa Fe, NM
    • Amad M., Winnik W., Schweingruber H., Mylchreest I., and Paul G. Determination of alprazolam in the presence of polypropylene glycol utilizing the high resolution capability of a triple quadrupole mass spectrometer. Proceeding of the 49th ASMS Conference on Mass Spectrometry and Allied Topics. Chicago, IL (2001), American Society for Mass Spectrometry, Santa Fe, NM
    • (2001) Proceeding of the 49th ASMS Conference on Mass Spectrometry and Allied Topics
    • Amad, M.1    Winnik, W.2    Schweingruber, H.3    Mylchreest, I.4    Paul, G.5
  • 83
    • 0012613145 scopus 로고    scopus 로고
    • Cassette dosing in drug discovery
    • Rossi D.T., and Sinz M.W. (Eds), Marcel Dekker, Santa Fe, NM
    • Vora J., Rossi D.T., and Kindt E.K. Cassette dosing in drug discovery. In: Rossi D.T., and Sinz M.W. (Eds). Mass Spectrometry in Drug Discovery (2002), Marcel Dekker, Santa Fe, NM 357-375
    • (2002) Mass Spectrometry in Drug Discovery , pp. 357-375
    • Vora, J.1    Rossi, D.T.2    Kindt, E.K.3
  • 84
    • 0034955150 scopus 로고    scopus 로고
    • Pharmacokinetic theory of cassette dosing in drug discovery screening
    • White R.E., and Manitpisitkul P. Pharmacokinetic theory of cassette dosing in drug discovery screening. Drug Metab. Dispos. 29 (2001) 957-966
    • (2001) Drug Metab. Dispos. , vol.29 , pp. 957-966
    • White, R.E.1    Manitpisitkul, P.2


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