Investigation of an enhanced resolution triple quadrupole mass spectrometer for high-throughput liquid chromatography/tandem mass spectrometry assays

Rapid Communications in Mass Spectrometry

Volumn 16, Issue 21, 2002, Pages 2060-2066

  Yang, Liyu ^a   Amad, Ma'an ^b   Winnik, Witold M ^b   Schoen, Alan E ^b   Schweingruber, Hans ^b   Mylchreest, Iain ^b   Rudewicz, Patrick J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Thermo Finnigan   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; DEGRADATION; DRUG PRODUCTS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; POLYPROPYLENES; SIGNAL TO NOISE RATIO; THROUGHPUT;

DYNAMIC RANGE; ENHANCED RESOLUTIONS; FULL WIDTHS AT HALF MAXIMUMS; HIGH-THROUGHPUT; MASS RESOLUTION; PROPYLENE GLYCOLS; QUADRUPOLE INSTRUMENT; TRIPLE QUADRUPOLE; TRIPLE-QUADRUPOLE MASS SPECTROMETER; UNIT RESOLUTIONS;

ASSAYS;

DESLORATADINE; DRUG; LORATADINE; MOMETASONE FUROATE; PIPERIDINE DERIVATIVE; POLYPROPYLENE; PREGNANE DERIVATIVE; PYRIDINE DERIVATIVE;

ARTICLE; CALIBRATION; CHROMATOGRAPHY; DIAGNOSTIC ACCURACY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHODOLOGY; MOLECULAR DYNAMICS; PROTON TRANSPORT; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; SIGNAL NOISE RATIO; TANDEM MASS SPECTROMETRY;

EID: 0036032589     PISSN: 09514198     EISSN: None     Source Type: Journal    
DOI: 10.1002/rcm.824     Document Type: Article

References (15)

1. Rule G, Chapple M, Henion J. Anal. Chem. 2001; 73: 439.
2. Zweigenbaum J, Heinig K, Steinborner S, Wachs T, Henion J. Anal. Chem. 1999; 71: 2294.
3. Watt AP, Morrison D, Locker KL, Evans DC. Anal. Chem. 2000; 72: 979.
4. Kaye B, Herron W, Macrae PV, Robinson S, Stopher DA, Venn RF, Wild W. Anal. Chem. 1996; 86: 1658.
5. Yang L, Wu N, Rudewicz P. J. Chromatogr. A 2001; 926: 43.
6. Zimmer D, Pickard V, Czembor W, Muller C. J. Chromatogr. A 1999; 854: 23.
7. McLoughlin DA, Olah TV, Gilbert JD. J. Pharm. Biomed. Anal. 1997; 15: 1893.
8. Yang L, Mann TD, Little D, Wu N, Clement R, Rudewicz P. Anal. Chem. 2001; 73: 1740.
9. Feng B, McQueney MS, Mezzasalma TM, Slemmon JR. Anal. Chem. 2001; 73: 5691.
10. Wu JT, Zeng H, Deng Y, Unger SE. Rapid Commun. Mass Spectrom. 2001; 15: 1113.
11. Hsieh Y, Wang G, Wang Y, Chackalamannil S, Brisson J, Ng K, Korfmacher WA. Rapid Commun. Mass Spectrom. 2002; 16: 944.
12. Shin YG, van Breemen RB. Biopharm. Drug Dispos. 2001; 22: 353.
13. Siuzdak G, Lewis JK. Biotechnol. Bioeng. 1998; 61: 127.
14. Clauwaert KM, Van Bocxlaer JF, Major HJ, Claereboudt JA, Lambert WE, Van den Eeckhout EM, Van Peteghem CH, De Leenheer AP. Rapid Commun. Mass Spectrom. 1999; 13: 1540.
15. Wang X, Plomley JB, Newman RA, Cisneros A. Anal. Chem. 2000; 72: 3547.