Liquid-liquid extraction using 96-well plate format in conjunction with liquid chromatography/tandem mass spectrometry for quantitative determination of methylphenidate (Ritalin®) in human plasma

Rapid Communications in Mass Spectrometry

Volumn 14, Issue 9, 2000, Pages 740-745

  Ramos, L ^a   Bakhtiar, R ^a,b   Tse, F L S ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOMATION; CURVE FITTING; ENANTIOSELECTIVITY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PLASMA (HUMAN); SOLVENT EXTRACTION;

96-WELL PLATE; ENANTIOSELECTIVE; HUMAN PLASMAS; LC-MS-MS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY; LIQUID-LIQUID EXTRACTION; LOWER LIMIT OF QUANTIFICATIONS; METHYLPHENIDATE; RITALIN;

REGRESSION ANALYSIS;

METHYLPHENIDATE;

ACCURACY; ARTICLE; ATTENTION DEFICIT DISORDER; AUTOMATION; BLOOD; BLOOD ANALYSIS; CALIBRATION; CONTROLLED STUDY; CURVE FITTING; DRUG DETERMINATION; HUMAN; INTERMETHOD COMPARISON; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MASS SPECTROMETRY; METHODOLOGY; NARCOLEPSY; REGRESSION ANALYSIS; REPRODUCIBILITY; ROBOTICS; STEREOISOMERISM; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

EID: 0034074783     PISSN: 09514198     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0231(20000515)14:9<740::AID-RCM938>3.0.CO;2-C     Document Type: Article

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