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Volumn 23, Issue 1, 2008, Pages 6-16

Toward biologically targeted therapy of calcium cycling defects in heart failure

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOTONIC AGENT; CYCLIC AMP DEPENDENT PROTEIN KINASE; PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 1; PROTEIN KINASE; PROTEIN KINASE (CALCIUM,CALMODULIN) II; RYANODINE RECEPTOR;

EID: 40349088965     PISSN: 15489213     EISSN: 15489221     Source Type: Journal    
DOI: 10.1152/physiol.00033.2007     Document Type: Review
Times cited : (34)

References (118)
  • 1
    • 40349084496 scopus 로고    scopus 로고
    • Calcium Up-Regulation by Percutaneous Administration of Gene Therapy In Cardiac Disease (C.U.P.I.D. Trial) (Online). http://www. celladon.net/press_may1707.php.
    • Calcium Up-Regulation by Percutaneous Administration of Gene Therapy In Cardiac Disease (C.U.P.I.D. Trial) (Online). http://www. celladon.net/press_may1707.php.
  • 4
    • 34547578672 scopus 로고    scopus 로고
    • Augmented protein kinase C-alpha-induced myofilament protein phosphorylation contributes to myofilament dysfunction in experimental congestive heart failure
    • Belin RJ, Sumandea MP, Allen EJ, Schoenfelt K, Wang H, Solaro RJ, de Tombe PP. Augmented protein kinase C-alpha-induced myofilament protein phosphorylation contributes to myofilament dysfunction in experimental congestive heart failure. Circ Res 101: 195-204, 2007.
    • (2007) Circ Res , vol.101 , pp. 195-204
    • Belin, R.J.1    Sumandea, M.P.2    Allen, E.J.3    Schoenfelt, K.4    Wang, H.5    Solaro, R.J.6    de Tombe, P.P.7
  • 5
    • 0031731303 scopus 로고    scopus 로고
    • Biophysical interaction between phospholamban and protein phosphatase 1 regulatory subunit GM
    • Berrebi-Bertrand I, Souchet M, Camelin JC, Laville MP, Calmels T, Bril A. Biophysical interaction between phospholamban and protein phosphatase 1 regulatory subunit GM. FEBS Lett 439: 224-230, 1998.
    • (1998) FEBS Lett , vol.439 , pp. 224-230
    • Berrebi-Bertrand, I.1    Souchet, M.2    Camelin, J.C.3    Laville, M.P.4    Calmels, T.5    Bril, A.6
  • 6
    • 0037049977 scopus 로고    scopus 로고
    • Cardiac excitation-contraction coupling
    • Bers DM. Cardiac excitation-contraction coupling. Nature 415: 198-205, 2002.
    • (2002) Nature , vol.415 , pp. 198-205
    • Bers, D.M.1
  • 7
    • 3242692393 scopus 로고    scopus 로고
    • Macromolecular complexes regulating cardiac ryanodine receptor function
    • Bers DM. Macromolecular complexes regulating cardiac ryanodine receptor function. J Mol Cell Cardiol 37: 417-429, 2004.
    • (2004) J Mol Cell Cardiol , vol.37 , pp. 417-429
    • Bers, D.M.1
  • 10
    • 85047679474 scopus 로고
    • cAMP concentrations, cAMP dependent protein kinase activity, and phospholamban in non-failing and failing myocardium
    • Bohm M, Reiger B, Schwinger RH, Erdmann E. cAMP concentrations, cAMP dependent protein kinase activity, and phospholamban in non-failing and failing myocardium. Cardiovasc Res 28: 1713-1719, 1994.
    • (1994) Cardiovasc Res , vol.28 , pp. 1713-1719
    • Bohm, M.1    Reiger, B.2    Schwinger, R.H.3    Erdmann, E.4
  • 11
    • 25444528255 scopus 로고    scopus 로고
    • Expression and phosphorylation of the napump regulatory subunit phospholemman in heart failure
    • Bossuyt J, Ai X, Moorman JR, Pogwizd SM, Bers DM. Expression and phosphorylation of the napump regulatory subunit phospholemman in heart failure. Circ Res 97: 558-565, 2005.
    • (2005) Circ Res , vol.97 , pp. 558-565
    • Bossuyt, J.1    Ai, X.2    Moorman, J.R.3    Pogwizd, S.M.4    Bers, D.M.5
  • 14
    • 33745839745 scopus 로고    scopus 로고
    • Maximum phosphorylation of the cardiac ryanodine receptor at serine-2809 by protein kinase a produces unique modifications to channel gating and conductance not observed at lower levels of phosphorylation
    • Carter S, Colyer J, Sitsapesan R. Maximum phosphorylation of the cardiac ryanodine receptor at serine-2809 by protein kinase a produces unique modifications to channel gating and conductance not observed at lower levels of phosphorylation. Circ Res 98: 1506-1513, 2006.
    • (2006) Circ Res , vol.98 , pp. 1506-1513
    • Carter, S.1    Colyer, J.2    Sitsapesan, R.3
  • 16
    • 0037144097 scopus 로고    scopus 로고
    • 2+ channel density and regulation are altered in failing human ventricular myocytes and recover after support with mechanical assist devices
    • 2+ channel density and regulation are altered in failing human ventricular myocytes and recover after support with mechanical assist devices. Circ Res 91: 517-524, 2002.
    • (2002) Circ Res , vol.91 , pp. 517-524
    • Chen, X.1    Piacentino 3rd, V.2    Furukawa, S.3    Goldman, B.4    Margulies, K.B.5    Houser, S.R.6
  • 19
    • 39049174776 scopus 로고    scopus 로고
    • Beyond small molecule drugs for heart failure: Prospects for gene therapy
    • discussion 256-259, 272-276
    • Chien KR. Beyond small molecule drugs for heart failure: prospects for gene therapy. Novartis Found Symp 274: 244-256; discussion 256-259, 272-276, 2006.
    • (2006) Novartis Found Symp , vol.274 , pp. 244-256
    • Chien, K.R.1
  • 20
    • 0034648805 scopus 로고    scopus 로고
    • Genomic circuits and the integrative biology of cardiac diseases
    • Chien KR. Genomic circuits and the integrative biology of cardiac diseases. Nature 407: 227-232, 2000.
    • (2000) Nature , vol.407 , pp. 227-232
    • Chien, K.R.1
  • 21
    • 0033520388 scopus 로고    scopus 로고
    • Stress pathways and heart failure
    • Chien KR. Stress pathways and heart failure. Cell 98: 555-558, 1999.
    • (1999) Cell , vol.98 , pp. 555-558
    • Chien, K.R.1
  • 22
    • 0038578664 scopus 로고    scopus 로고
    • Calcium and heart failure: The cycle game
    • Chien KR, Ross J Jr, Hoshijima M. Calcium and heart failure: the cycle game. Nat Med 9: 508-509, 2003.
    • (2003) Nat Med , vol.9 , pp. 508-509
    • Chien, K.R.1    Ross Jr, J.2    Hoshijima, M.3
  • 23
    • 33847058737 scopus 로고    scopus 로고
    • Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase
    • Curran J, Hinton MJ, Rios E, Bers DM, Shannon TR. Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase. Circ Res 100: 391-398, 2007.
    • (2007) Circ Res , vol.100 , pp. 391-398
    • Curran, J.1    Hinton, M.J.2    Rios, E.3    Bers, D.M.4    Shannon, T.R.5
  • 25
    • 0012300264 scopus 로고    scopus 로고
    • Re-evaluating sarcoplasmic reticulum function in heart failure
    • Delling U, Sussman MA, Molkentin JD. Re-evaluating sarcoplasmic reticulum function in heart failure. Nat Med 6: 942-943, 2000.
    • (2000) Nat Med , vol.6 , pp. 942-943
    • Delling, U.1    Sussman, M.A.2    Molkentin, J.D.3
  • 27
    • 33646777831 scopus 로고    scopus 로고
    • Compartmentation of cyclic nucleotide signaling in the heart: The role of A-kinase anchoring proteins
    • Dodge-Kafka KL, Langeberg L, Scott JD. Compartmentation of cyclic nucleotide signaling in the heart: the role of A-kinase anchoring proteins. Circ Res 98: 993-1001, 2006.
    • (2006) Circ Res , vol.98 , pp. 993-1001
    • Dodge-Kafka, K.L.1    Langeberg, L.2    Scott, J.D.3
  • 30
    • 33748751670 scopus 로고    scopus 로고
    • Trafficking of G protein-coupled receptors
    • Drake MT, Shenoy SK, Lefkowitz RJ. Trafficking of G protein-coupled receptors. Circ Res 99: 570-582, 2006.
    • (2006) Circ Res , vol.99 , pp. 570-582
    • Drake, M.T.1    Shenoy, S.K.2    Lefkowitz, R.J.3
  • 31
    • 0028175067 scopus 로고
    • 2+/calmodulin-dependent protein kinase isoforms
    • 2+/calmodulin-dependent protein kinase isoforms. Biochim Biophys Acta 1221: 89-101, 1994.
    • (1994) Biochim Biophys Acta , vol.1221 , pp. 89-101
    • Edman, C.F.1    Schulman, H.2
  • 32
    • 0347357650 scopus 로고    scopus 로고
    • Decreased protein and phosphorylation level of the protein phosphatase inhibitor-1 in failing human hearts
    • El-Armouche A, Pamminger T, Ditz D, Zolk O, Eschenhagen T. Decreased protein and phosphorylation level of the protein phosphatase inhibitor-1 in failing human hearts. Cardiovasc Res 61: 87-93, 2004.
    • (2004) Cardiovasc Res , vol.61 , pp. 87-93
    • El-Armouche, A.1    Pamminger, T.2    Ditz, D.3    Zolk, O.4    Eschenhagen, T.5
  • 34
    • 0141817953 scopus 로고    scopus 로고
    • Sorcin inhibits calcium release and modulates excitation-contraction coupling in the heart
    • Farrell EF, Antaramian A, Rueda A, Gomez AM, Valdivia HH. Sorcin inhibits calcium release and modulates excitation-contraction coupling in the heart. J Biol Chem 278: 34660-34666, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 34660-34666
    • Farrell, E.F.1    Antaramian, A.2    Rueda, A.3    Gomez, A.M.4    Valdivia, H.H.5
  • 36
    • 33747431210 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II phosphorylation of ryanodine receptor does affect calcium sparks in mouse ventricular myocytes
    • 2+/calmodulin-dependent protein kinase II phosphorylation of ryanodine receptor does affect calcium sparks in mouse ventricular myocytes. Circ Res 99: 398-406, 2006.
    • (2006) Circ Res , vol.99 , pp. 398-406
    • Guo, T.1    Zhang, T.2    Mestril, R.3    Bers, D.M.4
  • 37
    • 0344009618 scopus 로고    scopus 로고
    • Cardiac SR-coupled PP1 activity and expression are increased and inhibitor 1 protein expression is decreased in failing hearts
    • Gupta RC, Mishra S, Rastogi S, Imai M, Habib O, Sabbah HN. Cardiac SR-coupled PP1 activity and expression are increased and inhibitor 1 protein expression is decreased in failing hearts. Am J Physiol Heart Circ Physiol 285: H2373-H2381, 2003.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Gupta, R.C.1    Mishra, S.2    Rastogi, S.3    Imai, M.4    Habib, O.5    Sabbah, H.N.6
  • 38
    • 14244249503 scopus 로고    scopus 로고
    • Reduced inhibitor 1 and 2 activity is associated with increased protein phosphatase type 1 activity in left ventricular myocardium of one-kidney, one-clip hypertensive rats
    • Gupta RC, Mishra S, Yang XP, Sabbah HN. Reduced inhibitor 1 and 2 activity is associated with increased protein phosphatase type 1 activity in left ventricular myocardium of one-kidney, one-clip hypertensive rats. Mol Cell Biochem 269: 49-57, 2005.
    • (2005) Mol Cell Biochem , vol.269 , pp. 49-57
    • Gupta, R.C.1    Mishra, S.2    Yang, X.P.3    Sabbah, H.N.4
  • 42
    • 0036702666 scopus 로고    scopus 로고
    • Calcium cycling in congestive heart failure
    • Hasenfuss G, Pieske B. Calcium cycling in congestive heart failure. J Mol Cell Cardiol 34: 951-969, 2002.
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 951-969
    • Hasenfuss, G.1    Pieske, B.2
  • 44
    • 14344252909 scopus 로고    scopus 로고
    • Gene therapy targeted at calcium handling as an approach to the treatment of heart failure
    • Hoshijima M. Gene therapy targeted at calcium handling as an approach to the treatment of heart failure. Pharmacol Ther 105: 211-228, 2005.
    • (2005) Pharmacol Ther , vol.105 , pp. 211-228
    • Hoshijima, M.1
  • 45
    • 0036213057 scopus 로고    scopus 로고
    • Mixed signals in heart failure: Cancer rules
    • Hoshijima M, Chien KR. Mixed signals in heart failure: cancer rules. J Clin Invest 109: 849-855, 2002.
    • (2002) J Clin Invest , vol.109 , pp. 849-855
    • Hoshijima, M.1    Chien, K.R.2
  • 47
    • 33751065132 scopus 로고    scopus 로고
    • Reversal of calcium cycling defects in advanced heart failure toward molecular therapy
    • Hoshijima M, Knoll R, Pashmforoush M, Chien KR. Reversal of calcium cycling defects in advanced heart failure toward molecular therapy. J Am Coll Cardiol 48: 15-23, 2006.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 15-23
    • Hoshijima, M.1    Knoll, R.2    Pashmforoush, M.3    Chien, K.R.4
  • 48
    • 0032724685 scopus 로고    scopus 로고
    • Diminished basal phosphorylation level of phospholamban in the postinfarction remodeled rat ventricle: Role of beta-adrenergic pathway, G(i) protein, phosphodiesterase, and phosphatases
    • Huang B, Wang S, Qin D, Boutjdir M, El-Sherif N. Diminished basal phosphorylation level of phospholamban in the postinfarction remodeled rat ventricle: role of beta-adrenergic pathway, G(i) protein, phosphodiesterase, and phosphatases. Circ Res 85: 848-855, 1999.
    • (1999) Circ Res , vol.85 , pp. 848-855
    • Huang, B.1    Wang, S.2    Qin, D.3    Boutjdir, M.4    El-Sherif, N.5
  • 49
    • 0033592754 scopus 로고    scopus 로고
    • Signaling pathways for cardiac hypertrophy and failure
    • Hunter JJ, Chien KR. Signaling pathways for cardiac hypertrophy and failure. N Engl J Med 341: 1276-1283, 1999.
    • (1999) N Engl J Med , vol.341 , pp. 1276-1283
    • Hunter, J.J.1    Chien, K.R.2
  • 52
    • 0036073345 scopus 로고    scopus 로고
    • Contributions of protein kinase A anchoring proteins to compartmentation of cAMP signaling in the heart
    • Kapiloff MS. Contributions of protein kinase A anchoring proteins to compartmentation of cAMP signaling in the heart. Mol Pharmacol 62: 193-199, 2002.
    • (2002) Mol Pharmacol , vol.62 , pp. 193-199
    • Kapiloff, M.S.1
  • 59
    • 0035955601 scopus 로고    scopus 로고
    • 2+-binding protein) and triadin in the lumen of sarcoplasmic reticulum
    • 2+-binding protein) and triadin in the lumen of sarcoplasmic reticulum. J Biol Chem 276: 39533-39538, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 39533-39538
    • Lee, H.G.1    Kang, H.2    Kim, D.H.3    Park, W.J.4
  • 61
    • 0037155056 scopus 로고    scopus 로고
    • Protein kinase A phosphorylation of the ryanodine receptor does not affect calcium sparks in mouse ventricular myocytes
    • Li Y, Kranias EG, Mignery GA, Bers DM. Protein kinase A phosphorylation of the ryanodine receptor does not affect calcium sparks in mouse ventricular myocytes. Circ Res 90: 309-316, 2002.
    • (2002) Circ Res , vol.90 , pp. 309-316
    • Li, Y.1    Kranias, E.G.2    Mignery, G.A.3    Bers, D.M.4
  • 64
    • 0026016543 scopus 로고
    • Identification of the major protein phosphatases in mammalian cardiac muscle which dephosphorylate phospholamban
    • MacDougall LK, Jones LR, Cohen P. Identification of the major protein phosphatases in mammalian cardiac muscle which dephosphorylate phospholamban. Eur J Biochem 196: 725-734, 1991.
    • (1991) Eur J Biochem , vol.196 , pp. 725-734
    • MacDougall, L.K.1    Jones, L.R.2    Cohen, P.3
  • 65
    • 33846894117 scopus 로고    scopus 로고
    • 2+/calmodulin kinases in the heart: Physiology and pathophysiology
    • 2+/calmodulin kinases in the heart: physiology and pathophysiology. Cardiovasc Res 73: 629-630, 2007.
    • (2007) Cardiovasc Res , vol.73 , pp. 629-630
    • Maier, L.S.1    Bers, D.M.2    Brown, J.H.3
  • 67
    • 0034640113 scopus 로고    scopus 로고
    • PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts
    • Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, Marks AR. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 101: 365-376, 2000.
    • (2000) Cell , vol.101 , pp. 365-376
    • Marx, S.O.1    Reiken, S.2    Hisamatsu, Y.3    Jayaraman, T.4    Burkhoff, D.5    Rosemblit, N.6    Marks, A.R.7
  • 69
    • 1042302791 scopus 로고    scopus 로고
    • Covalent and noncovalent modification of thin filament action: The essential role of troponin in cardiac muscle regulation
    • Metzger JM, Westfall MV. Covalent and noncovalent modification of thin filament action: the essential role of troponin in cardiac muscle regulation. Circ Res 94: 146-158, 2004.
    • (2004) Circ Res , vol.94 , pp. 146-158
    • Metzger, J.M.1    Westfall, M.V.2
  • 72
    • 0038237303 scopus 로고    scopus 로고
    • Atrial chamber-specific expression of sarcolipin is regulated during development and hypertrophic remodeling
    • Minamisawa S, Wang Y, Chen J, Ishikawa Y, Chien KR, Matsuoka R. Atrial chamber-specific expression of sarcolipin is regulated during development and hypertrophic remodeling. J Biol Chem 278: 9570-9575, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 9570-9575
    • Minamisawa, S.1    Wang, Y.2    Chen, J.3    Ishikawa, Y.4    Chien, K.R.5    Matsuoka, R.6
  • 74
    • 0037362521 scopus 로고    scopus 로고
    • 2+- calmodulin-dependent protein kinase activity and expression in LV myocardium of dogs with heart failure
    • 2+- calmodulin-dependent protein kinase activity and expression in LV myocardium of dogs with heart failure. Am J Physiol Heart Circ Physiol 284: H876-H883, 2003.
    • (2003) Am J Physiol Heart Circ Physiol , vol.284
    • Mishra, S.1    Sabbah, H.N.2    Jain, J.C.3    Gupta, R.C.4
  • 76
    • 33646737382 scopus 로고    scopus 로고
    • Monitoring of cAMP synthesis and degradation in living cells
    • Nikolaev VO, Lohse MJ. Monitoring of cAMP synthesis and degradation in living cells. Physiology Bethesda 21: 86-92, 2006.
    • (2006) Physiology Bethesda , vol.21 , pp. 86-92
    • Nikolaev, V.O.1    Lohse, M.J.2
  • 79
    • 0029095444 scopus 로고
    • Alterations in intracellular calcium handling associated with the inverse force-frequency relation in human dilated cardiomyopathy
    • Pieske B, Kretschmann B, Meyer M, Holubarsch C, Weirich J, Posival H, Minami K, Just H, Hasenfuss G. Alterations in intracellular calcium handling associated with the inverse force-frequency relation in human dilated cardiomyopathy. Circulation 92: 1169-1178, 1995.
    • (1995) Circulation , vol.92 , pp. 1169-1178
    • Pieske, B.1    Kretschmann, B.2    Meyer, M.3    Holubarsch, C.4    Weirich, J.5    Posival, H.6    Minami, K.7    Just, H.8    Hasenfuss, G.9
  • 80
    • 34547113756 scopus 로고    scopus 로고
    • Phosphorylation of human inhibitor-1 at Ser67 and/or Thr75 attenuates stimulatory effects of protein kinase A signaling in cardiac myocytes
    • Rodriguez P, Mitton B, Nicolaou P, Chen G, Kranias EG. Phosphorylation of human inhibitor-1 at Ser67 and/or Thr75 attenuates stimulatory effects of protein kinase A signaling in cardiac myocytes. Am J Physiol Heart Circ Physiol 293: H762-H769, 2007.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Rodriguez, P.1    Mitton, B.2    Nicolaou, P.3    Chen, G.4    Kranias, E.G.5
  • 81
    • 33845996595 scopus 로고    scopus 로고
    • Identification of a novel phosphorylation site in protein phosphatase inhibitor-1 as a negative regulator of cardiac function
    • Rodriguez P, Mitton B, Waggoner JR, Kranias EG. Identification of a novel phosphorylation site in protein phosphatase inhibitor-1 as a negative regulator of cardiac function. J Biol Chem 281: 38599-38608, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 38599-38608
    • Rodriguez, P.1    Mitton, B.2    Waggoner, J.R.3    Kranias, E.G.4
  • 83
    • 0036164778 scopus 로고    scopus 로고
    • Reduced level of serine(16) phosphorylated phospholamban in the failing rat myocardium: A major contributor to reduced SERCA2 activity
    • Sande JB, Sjaastad I, Hoen IB, Bokenes J, Tonnessen T, Holt E, Lunde PK, Christensen G. Reduced level of serine(16) phosphorylated phospholamban in the failing rat myocardium: a major contributor to reduced SERCA2 activity. Cardiovasc Res 53: 382-391, 2002.
    • (2002) Cardiovasc Res , vol.53 , pp. 382-391
    • Sande, J.B.1    Sjaastad, I.2    Hoen, I.B.3    Bokenes, J.4    Tonnessen, T.5    Holt, E.6    Lunde, P.K.7    Christensen, G.8
  • 88
    • 33847083224 scopus 로고    scopus 로고
    • CaM or cAMP: Linking beta-adrenergic stimulation to 'leaky' RyRs
    • Sipido KR. CaM or cAMP: linking beta-adrenergic stimulation to 'leaky' RyRs. Circ Res 100: 296-298, 2007.
    • (2007) Circ Res , vol.100 , pp. 296-298
    • Sipido, K.R.1
  • 90
    • 0345803003 scopus 로고    scopus 로고
    • Characterization of recombinant skeletal muscle (Ser-2843) and cardiac muscle (Ser-2809) ryanodine receptor phosphorylation mutants
    • Stange M, Xu L, Balshaw D, Yamaguchi N, Meissner G. Characterization of recombinant skeletal muscle (Ser-2843) and cardiac muscle (Ser-2809) ryanodine receptor phosphorylation mutants. J Biol Chem 278: 51693-51702, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 51693-51702
    • Stange, M.1    Xu, L.2    Balshaw, D.3    Yamaguchi, N.4    Meissner, G.5
  • 91
    • 0035029169 scopus 로고    scopus 로고
    • Compartmentation of G protein-coupled signaling pathways in cardiac myocytes
    • Steinberg SF, Brunton LL. Compartmentation of G protein-coupled signaling pathways in cardiac myocytes. Annu Rev Pharmacol Toxicol 41: 751-773, 2001.
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 751-773
    • Steinberg, S.F.1    Brunton, L.L.2
  • 94
    • 0035815666 scopus 로고    scopus 로고
    • Myomegalin is a novel protein of the golgi/centrosome that interacts with a cyclic nucleotide phosphodiesterase
    • Verde I, Pahlke G, Salanova M, Zhang G, Wang S, Coletti D, Onuffer J, Jin SL, Conti M. Myomegalin is a novel protein of the golgi/centrosome that interacts with a cyclic nucleotide phosphodiesterase. J Biol Chem 276: 11189-11198, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 11189-11198
    • Verde, I.1    Pahlke, G.2    Salanova, M.3    Zhang, G.4    Wang, S.5    Coletti, D.6    Onuffer, J.7    Jin, S.L.8    Conti, M.9
  • 98
    • 3042763171 scopus 로고    scopus 로고
    • 2+/calmodulin- dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor
    • 2+/calmodulin- dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor. Circ Res 94: e61-e70, 2004.
    • (2004) Circ Res , vol.94
    • Wehrens, X.H.1    Lehnart, S.E.2    Reiken, S.R.3    Marks, A.R.4
  • 101
  • 102
    • 0035957010 scopus 로고    scopus 로고
    • Calmodulin kinase is a molecular switch for cardiac excitation-contraction coupling
    • Wu Y, Colbran RJ, Anderson ME. Calmodulin kinase is a molecular switch for cardiac excitation-contraction coupling. Proc Natl Acad Sci USA 98: 2877-2881, 2001.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 2877-2881
    • Wu, Y.1    Colbran, R.J.2    Anderson, M.E.3
  • 103
    • 17144439929 scopus 로고    scopus 로고
    • Beta-adrenergic signaling in the heart: Dual coupling of the beta2-adrenergic receptor to Gs and Gi proteins
    • Xiao RP. Beta-adrenergic signaling in the heart: dual coupling of the beta2-adrenergic receptor to Gs and Gi proteins. Sci STKE 2001: RE15, 2001.
    • (2001) Sci STKE , vol.2001
    • Xiao, R.P.1
  • 104
    • 33845611066 scopus 로고    scopus 로고
    • Inhibition of protein phosphatase 1 by inhibitor-2 gene delivery ameliorates heart failure progression in genetic cardiomyopathy
    • Yamada M, Ikeda Y, Yano M, Yoshimura K, Nishino S, Aoyama H, Wang L, Aoki H, Matsuzaki M. Inhibition of protein phosphatase 1 by inhibitor-2 gene delivery ameliorates heart failure progression in genetic cardiomyopathy. FASEB J 20: 1197-1199, 2006.
    • (2006) FASEB J , vol.20 , pp. 1197-1199
    • Yamada, M.1    Ikeda, Y.2    Yano, M.3    Yoshimura, K.4    Nishino, S.5    Aoyama, H.6    Wang, L.7    Aoki, H.8    Matsuzaki, M.9
  • 105
    • 33847040677 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase deltaC activate or inhibit the cardiac ryanodine receptor ion channel?
    • 2+/calmodulin-dependent protein kinase deltaC activate or inhibit the cardiac ryanodine receptor ion channel? Circ Res 100: 293-295, 2007.
    • (2007) Circ Res , vol.100 , pp. 293-295
    • Yamaguchi, N.1    Meissner, G.2
  • 106
    • 33947494913 scopus 로고    scopus 로고
    • Regulation of phosphodiesterase 3 and inducible cAMP early repressor in the heart
    • Yan C, Miller CL, Abe J. Regulation of phosphodiesterase 3 and inducible cAMP early repressor in the heart. Circ Res 100: 489-501, 2007.
    • (2007) Circ Res , vol.100 , pp. 489-501
    • Yan, C.1    Miller, C.L.2    Abe, J.3
  • 111
    • 34250156365 scopus 로고    scopus 로고
    • cAMP and cGMP signaling cross-talk: Role of phosphodiesterases and implications for cardiac pathophysiology
    • Zaccolo M, Movsesian MA. cAMP and cGMP signaling cross-talk: role of phosphodiesterases and implications for cardiac pathophysiology. Circ Res 100: 1569-1578, 2007.
    • (2007) Circ Res , vol.100 , pp. 1569-1578
    • Zaccolo, M.1    Movsesian, M.A.2
  • 112
    • 0030770826 scopus 로고    scopus 로고
    • Complex formation between junctin, triadin, calsequestrin, and the ryanodine receptor. Proteins of the cardiac junctional sarcoplasmic reticulum membrane
    • Zhang L, Kelley J, Schmeisser G, Kobayashi YM, Jones LR. Complex formation between junctin, triadin, calsequestrin, and the ryanodine receptor. Proteins of the cardiac junctional sarcoplasmic reticulum membrane. J Biol Chem 272: 23389-23397, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 23389-23397
    • Zhang, L.1    Kelley, J.2    Schmeisser, G.3    Kobayashi, Y.M.4    Jones, L.R.5
  • 114
    • 3242744450 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II in cardiac hypertrophy and heart failure
    • 2+/calmodulin-dependent protein kinase II in cardiac hypertrophy and heart failure. Cardiovasc Res 63: 476-486, 2004.
    • (2004) Cardiovasc Res , vol.63 , pp. 476-486
    • Zhang, T.1    Brown, J.H.2
  • 116
    • 0038643573 scopus 로고    scopus 로고
    • The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure
    • Zhang T, Maier LS, Dalton ND, Miyamoto S, Ross J Jr, Bers DM, Brown JH. The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure. Circ Res 92: 912-919, 2003.
    • (2003) Circ Res , vol.92 , pp. 912-919
    • Zhang, T.1    Maier, L.S.2    Dalton, N.D.3    Miyamoto, S.4    Ross Jr, J.5    Bers, D.M.6    Brown, J.H.7


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