Phosphorylation-dependent regulation of ryanodine receptors: A novel role for leucine/isoleucine zippers

Journal of Cell Biology

Volumn 153, Issue 4, 2001, Pages 699-708

  Marx, Steven O ^a   Reiken, Steven ^a   Hisamatsu, Yuji ^a   Gaburjakova, Marta ^a   Gaburjakova, Jana ^a   Yang, Yi Ming ^a   Rosemblit, Nora ^a   Marks, Andrew R ^a  

^a The New York Presbyterian Hospital   (United States)

Author keywords

Calcium channel; Leucine zipper; Phosphatase; Phosphorylation; Ryanodine receptor

Indexed keywords

CALCIUM CHANNEL; ION CHANNEL; LEUCINE ZIPPER PROTEIN; PHOSPHATASE; PHOSPHOTRANSFERASE; RYANODINE RECEPTOR;

ARTICLE; BINDING SITE; CALCIUM TRANSPORT; CHANNEL GATING; DEPHOSPHORYLATION; ENZYME ACTIVATION; MACROMOLECULE; MUSCLE CONTRACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; REGULATORY MECHANISM;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CALCIUM CHANNELS; CARRIER PROTEINS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOGS; ISOLEUCINE; LEUCINE ZIPPERS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MYOCARDIUM; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL;

EID: 0035858868     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.153.4.699     Document Type: Article

References (47)

1. Replacements of Pro86 in phage T4 lysozyme extend an alpha-helix but do not alter protein stability
2. Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines
3. Molecular characterization of an anchor protein (AKAPCE) that binds the RI subunit (RCE) of type I protein kinase A from Caenorhabditis elegans
4. Helix geometry in proteins
5. Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein
6. Heptad breaks in α-helical coiled coils: Stutters and stammers
7. Interaction of the regulatory subunit (RII) of cAMP-dependent protein kinase with RII-anchoring proteins occurs through an amphipathic helix binding motif
8. Proline affects oligomerization of a coiled coil by inducing a kink in a long helix
9. Cloning and characterization of fiber type-specific ryanodine receptor isoforms in skeletal muscles of fish
10. Subunit oligomerization, and topology of the inositol 1,4,5-trisphosphate receptor
11. Primary structure and distribution of a novel ryanodine receptor/calcium release channel from rabbit brain
12. A switch between two-, three- and four-stranded coiled coils in GCN4 leucine zipper mutants
13. Structure of lamprey haemoglobin
14. Characterization of the neuronal targeting protein spinophilin and its interaction with protein phosphatase-1
15. Protein kinases and phosphatases: The yin and yang of protein phosphorylation and signaling
16. Functional coupling between glycolysis and excitation-contraction coupling underlies alternans in cat heart cells
17. FK506 binding protein associated with the calcium release channel (ryanodine receptor)
18. hSK4, a member of a novel subfamily of calcium-activated potassium channels
19. The roles of ion channels in an inherited heart disease: Molecular genetics of the long QT syndrome
20. SH2 and SH3 domains: Elements that control interactions of cytoplasmic signaling proteins
21. The leucine zipper: A hypothetical structure common to a new class of DNA binding proteins
22. Coiled coils: New structures and new functions
23. Cellular functions of immunophilins
24. Cardiac intracellular calcium release channels: Role in heart failure
25. Molecular cloning and characterization of the ryanodine receptor/junctional channel complex cDNA from skeletal muscle sarcoplasmic reticulum
26. 2+ release channels (ryanodine receptors)
27. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts
28. unc-68 encodes a ryanodine receptor involved in regulating C. elegans body-wall muscle contraction
29. Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation
30. + channels
31. Leucine is the most stabilizing aliphatic amino acid in the d position of a dimeric leucine zipper coiled coil
32. Primary structure and functional expression from cDNA of the cardiac ryanodine receptor/calcium release channel
33. 2+ release channel (ryanodine receptor) of rabbit cardiac muscle sarcoplasmic reticulum
34. Primary structure and distribution of ryanodine-binding protein isoforms of the bullfrog skeletal muscle
35. SH2 and SH3 domains: From structure to function
36. A leucine zipper stabilizes the pentameric membrane domain of phospholamban and forms a coiled-coil pore structure
37. Regulation of myosin phosphatase by a specific interaction with cGMP-dependent protein kinase I alpha
38. Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor
39. Isolation and characterization of a gene for a ryanodine receptor/calcium release channel in Drosophila melanogaster
40. Effects of side-chain characteristics on stability and oligomerization state of a de novo-designed model coiled-coil: 20 Amino acid substitutions in position "d"
41. Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers
42. The role of position a in determining the stability and oligomerization state of alpha-helical coiled coils: 20 Amino acid stability coefficients in the hydrophobic core of the proteins
43. Molecular cloning of cDNA encoding a drosophila ryanodine receptor and functional studies of the carboxyl-terminal calcium release channel
44. Protein phosphatase I modulation of neostriatal AMPA channels: Regulation by DARPP-32 and spinophilin
45. The catalytic subunits of Ser/Thr protein phosphatases from Caenorhabditis elegans
46. The variable subunit associated with protein phosphatase 2A0 defines a novel multimember family of regulatory subunits
47. 2+ release channel (ryanodine receptor) of skeletal muscle sarcoplasmic reticulum